NO20090214L - Proteinkinase C aktivitetsforsterker inneholdende alkyleterderivat eller et salt av denne - Google Patents
Proteinkinase C aktivitetsforsterker inneholdende alkyleterderivat eller et salt av denneInfo
- Publication number
- NO20090214L NO20090214L NO20090214A NO20090214A NO20090214L NO 20090214 L NO20090214 L NO 20090214L NO 20090214 A NO20090214 A NO 20090214A NO 20090214 A NO20090214 A NO 20090214A NO 20090214 L NO20090214 L NO 20090214L
- Authority
- NO
- Norway
- Prior art keywords
- group
- protein kinase
- salt
- ether derivative
- alkyl ether
- Prior art date
Links
- 102000003923 Protein Kinase C Human genes 0.000 title abstract 4
- 108090000315 Protein Kinase C Proteins 0.000 title abstract 4
- 239000003623 enhancer Substances 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 2
- 150000005215 alkyl ethers Chemical class 0.000 title 1
- 125000003277 amino group Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Beskrevet er en proteinkinase C forsterker karakterisert ved at den inneholder et benzotiofenalkyleterderivat representert ved den generelle formel nedenfor eller et salt derav. (I formelen, R1 og R2 kan være like eller forskjellige og representerer én eller flere grupper valgt fra et hydrogenatom, et halogenatom, en alkylgruppe, en arylgruppe, en aralkylgruppe, en alkoksygruppe, en aryloksygruppe, en alkenylgruppe, en aminogruppe, en heterocyklisk gruppe, en eventuelt beskyttet aminogruppe, en hydroksylgruppe, en karboksylgruppe, en oksogruppe og lignende; R3 representerer en alkylaminogruppe, en aminogruppe, en hydroksylgruppe eller lignende; og m og n kan være like eller forskjellige og representerer et helt tall på 1-6.) Denne proteinkinase C forsterker er anvendelige for behandling eller forebygging av forskjellige sykdommer forbundet med proteinkinase C.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006212722 | 2006-08-04 | ||
| PCT/JP2007/065165 WO2008016107A1 (fr) | 2006-08-04 | 2007-08-02 | Amplificateur de l'activité de la protéine kinase c contenant un dérivé d'éther d'alkyle ou un sel de celui-ci |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20090214L true NO20090214L (no) | 2009-01-30 |
Family
ID=38997281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20090214A NO20090214L (no) | 2006-08-04 | 2009-01-14 | Proteinkinase C aktivitetsforsterker inneholdende alkyleterderivat eller et salt av denne |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US8173633B2 (no) |
| EP (1) | EP2048145B9 (no) |
| JP (1) | JP5255441B2 (no) |
| KR (1) | KR20090038471A (no) |
| CN (1) | CN101501026B (no) |
| AT (1) | ATE491705T1 (no) |
| AU (1) | AU2007279673B2 (no) |
| BR (1) | BRPI0715056A2 (no) |
| CA (1) | CA2659835A1 (no) |
| CY (1) | CY1111691T1 (no) |
| DE (1) | DE602007011281D1 (no) |
| DK (1) | DK2048145T3 (no) |
| ES (1) | ES2355768T3 (no) |
| IL (1) | IL196754A0 (no) |
| MX (1) | MX2009001255A (no) |
| NO (1) | NO20090214L (no) |
| NZ (1) | NZ574551A (no) |
| PL (1) | PL2048145T3 (no) |
| PT (1) | PT2048145E (no) |
| SI (1) | SI2048145T1 (no) |
| WO (1) | WO2008016107A1 (no) |
| ZA (1) | ZA200900743B (no) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0213393B8 (pt) | 2001-10-19 | 2021-05-25 | Fujifilm Toyama Chemical Co Ltd | derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica |
| ATE491705T1 (de) * | 2006-08-04 | 2011-01-15 | Toyama Chemical Co Ltd | Verstärker der aktivität von proteinkinase c, enthaltend ein alkyletherderivat oder ein salz davon |
| CN102046620B (zh) * | 2008-05-28 | 2014-04-09 | 富山化学工业株式会社 | 新的苯并噻吩氧化物衍生物及其盐 |
| CA2853024C (en) | 2011-11-11 | 2017-08-22 | Pfizer Inc. | 2-thiopyrimidinones |
| US9872914B2 (en) | 2012-02-22 | 2018-01-23 | Toyama Chemical Co., Ltd. | Solid pharmaceutical composition containing 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salt thereof |
| US10238632B2 (en) | 2015-06-11 | 2019-03-26 | Fujifilm Toyama Chemical Co., Ltd. | Sigma receptor-binding agent |
| WO2017111005A1 (ja) * | 2015-12-25 | 2017-06-29 | 富山化学工業株式会社 | １－（３－（２－（１－ベンゾチオフェン－５－イル）エトキシ）プロピル）アゼチジン－３－オールまたはその塩を含む錠剤 |
| CN110139641B (zh) * | 2016-12-28 | 2022-09-09 | 富士胶片富山化学株式会社 | 外用组合物 |
| CN110121342A (zh) * | 2016-12-28 | 2019-08-13 | 富士胶片富山化学株式会社 | 医药组合物 |
| CN110167551B (zh) * | 2016-12-28 | 2022-06-14 | 富士胶片富山化学株式会社 | 医药组合物 |
| JP7079209B2 (ja) | 2016-12-28 | 2022-06-01 | 富士フイルム富山化学株式会社 | 医薬組成物およびその製造方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995017888A1 (en) | 1993-12-30 | 1995-07-06 | Smithkline Beecham Corporation | Phenylmethyl hexanamides, and the use thereof |
| US6809092B2 (en) | 2000-01-26 | 2004-10-26 | Ono Pharmaceutical Co., Ltd. | Benezene-fused heteroring derivatives and pharmaceutical agents comprising the same as active ingredient |
| JP4303435B2 (ja) * | 2001-02-26 | 2009-07-29 | 富山化学工業株式会社 | ミトコンドリア機能賦活剤 |
| BRPI0213393B8 (pt) * | 2001-10-19 | 2021-05-25 | Fujifilm Toyama Chemical Co Ltd | derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica |
| US6825229B2 (en) | 2002-03-07 | 2004-11-30 | Blanchette Rockefeller Neurosciences Institute | Methods for Alzheimer's Disease treatment and cognitive enhancement |
| SI1514542T1 (sl) * | 2002-06-14 | 2012-06-29 | Toyama Chemical Co Ltd | Farmacevtska sestava, vsebujoäśa takrin ali donepezil za izboljĺ anje moĺ˝ganske funkcije |
| EP1597223B1 (en) * | 2003-01-23 | 2017-02-22 | Esperion Therapeutics Inc. | Hydroxyl compounds and compositions for cholesterol management and related uses |
| ZA200508166B (en) * | 2003-04-17 | 2007-03-28 | Toyama Chemical Co Ltd | Preventive/remedy for retinal nerve diseases containing alkyl ether derivatives or salts thereof |
| SE529122C2 (sv) * | 2004-09-24 | 2007-05-02 | Jokab Safety Ab | Skyddsanordning för områdesbegränsning och övervakning |
| EP1864978A4 (en) * | 2005-03-28 | 2009-07-01 | Toyama Chemical Co Ltd | PROCESS FOR PRODUCING 1- (3- (2- (1-BENZOTHIOPHEN-5-YL) -ETHOXY) PROPYL) AZETIDIN-3-OL OR ITS SALTS |
| JP4902247B2 (ja) * | 2005-04-08 | 2012-03-21 | 富山化学工業株式会社 | ２−（１−ベンゾチオフェン−５−イル）エタノールの新規製造法およびその中間体 |
| ZA200808728B (en) * | 2006-04-26 | 2010-01-27 | Toyama Chemical Co Ltd | Neurogenesis inducer or neuropathy Therapeutic agent comprising alkyl ether derivative or salt thereof |
| ATE491705T1 (de) * | 2006-08-04 | 2011-01-15 | Toyama Chemical Co Ltd | Verstärker der aktivität von proteinkinase c, enthaltend ein alkyletherderivat oder ein salz davon |
-
2007
- 2007-08-02 AT AT07791845T patent/ATE491705T1/de active
- 2007-08-02 DE DE602007011281T patent/DE602007011281D1/de active Active
- 2007-08-02 PT PT07791845T patent/PT2048145E/pt unknown
- 2007-08-02 ES ES07791845T patent/ES2355768T3/es active Active
- 2007-08-02 BR BRPI0715056-3A patent/BRPI0715056A2/pt not_active IP Right Cessation
- 2007-08-02 JP JP2008527788A patent/JP5255441B2/ja not_active Expired - Fee Related
- 2007-08-02 MX MX2009001255A patent/MX2009001255A/es active IP Right Grant
- 2007-08-02 ZA ZA200900743A patent/ZA200900743B/xx unknown
- 2007-08-02 WO PCT/JP2007/065165 patent/WO2008016107A1/ja active Application Filing
- 2007-08-02 NZ NZ574551A patent/NZ574551A/en unknown
- 2007-08-02 CA CA002659835A patent/CA2659835A1/en not_active Abandoned
- 2007-08-02 US US12/376,296 patent/US8173633B2/en not_active Expired - Fee Related
- 2007-08-02 AU AU2007279673A patent/AU2007279673B2/en not_active Ceased
- 2007-08-02 DK DK07791845.6T patent/DK2048145T3/da active
- 2007-08-02 PL PL07791845T patent/PL2048145T3/pl unknown
- 2007-08-02 EP EP07791845A patent/EP2048145B9/en not_active Not-in-force
- 2007-08-02 CN CN2007800291310A patent/CN101501026B/zh not_active Expired - Fee Related
- 2007-08-02 SI SI200730516T patent/SI2048145T1/sl unknown
- 2007-08-02 KR KR1020097003927A patent/KR20090038471A/ko not_active Application Discontinuation
-
2009
- 2009-01-14 NO NO20090214A patent/NO20090214L/no not_active Application Discontinuation
- 2009-01-27 IL IL196754A patent/IL196754A0/en unknown
-
2011
- 2011-02-14 CY CY20111100176T patent/CY1111691T1/el unknown
- 2011-06-17 US US13/163,105 patent/US20110245228A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2048145B1 (en) | 2010-12-15 |
| PL2048145T3 (pl) | 2011-09-30 |
| CA2659835A1 (en) | 2008-02-07 |
| NZ574551A (en) | 2012-03-30 |
| CY1111691T1 (el) | 2015-10-07 |
| EP2048145B9 (en) | 2011-05-04 |
| DE602007011281D1 (de) | 2011-01-27 |
| EP2048145A1 (en) | 2009-04-15 |
| PT2048145E (pt) | 2011-01-14 |
| US20100184997A1 (en) | 2010-07-22 |
| EP2048145A4 (en) | 2009-09-09 |
| AU2007279673B2 (en) | 2012-04-19 |
| SI2048145T1 (sl) | 2011-04-29 |
| AU2007279673A1 (en) | 2008-02-07 |
| CN101501026B (zh) | 2012-04-04 |
| CN101501026A (zh) | 2009-08-05 |
| ZA200900743B (en) | 2010-05-26 |
| MX2009001255A (es) | 2009-06-12 |
| KR20090038471A (ko) | 2009-04-20 |
| ES2355768T3 (es) | 2011-03-30 |
| JP5255441B2 (ja) | 2013-08-07 |
| US8173633B2 (en) | 2012-05-08 |
| WO2008016107A1 (fr) | 2008-02-07 |
| US20110245228A1 (en) | 2011-10-06 |
| DK2048145T3 (da) | 2011-04-04 |
| BRPI0715056A2 (pt) | 2013-05-28 |
| JPWO2008016107A1 (ja) | 2009-12-24 |
| ATE491705T1 (de) | 2011-01-15 |
| IL196754A0 (en) | 2009-11-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |