WO2005025492A3 - Novel compositions, pharmaceutical compositions, and methods for the treatment and prevention of heart disease - Google Patents
Novel compositions, pharmaceutical compositions, and methods for the treatment and prevention of heart disease Download PDFInfo
- Publication number
- WO2005025492A3 WO2005025492A3 PCT/US2004/022128 US2004022128W WO2005025492A3 WO 2005025492 A3 WO2005025492 A3 WO 2005025492A3 US 2004022128 W US2004022128 W US 2004022128W WO 2005025492 A3 WO2005025492 A3 WO 2005025492A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- prevention
- treatment
- methods
- heart disease
- compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/20—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention provides the following formula (I) and uses thereof wherein either R1 is hydrogen, and R2 is selected from the group consisting of alkyl, substituted alkyl, alkenyl, alkynyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, alkaryl, arylalkyl, heteroaryl, substituted heteroaryl, heterocycle, or substituted heterocycle; and R3 is selected from the group consisting of alkyl, substituted alkyl, C(O)R, and C(O)NHR.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48519103P | 2003-07-07 | 2003-07-07 | |
US60/485,191 | 2003-07-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005025492A2 WO2005025492A2 (en) | 2005-03-24 |
WO2005025492A3 true WO2005025492A3 (en) | 2005-08-11 |
Family
ID=34312155
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/022128 WO2005025492A2 (en) | 2003-07-07 | 2004-07-07 | Novel compositions, pharmaceutical compositions, and methods for the treatment and prevention of heart disease |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2005025492A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100004333A1 (en) * | 2004-12-17 | 2010-01-07 | Stocker Roland O | Compositions and methods for treating cardiovascular disorders |
CN106905208B (en) * | 2017-02-27 | 2018-09-07 | 江西瑞雅药业有限公司 | Probucol prodrug and preparation method thereof and pharmaceutical composition |
CN113209061A (en) * | 2020-03-16 | 2021-08-06 | 北京中美红格科技有限公司 | Pharmaceutical composition and preparation containing disulfotol and analogue for preventing and treating coronavirus pneumonia (containing COVID-19) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6121319A (en) * | 1997-05-14 | 2000-09-19 | Atherogenics, Inc. | Monoesters of probucol for the treatment of cardiovascular and inflammatory disease |
-
2004
- 2004-07-07 WO PCT/US2004/022128 patent/WO2005025492A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6121319A (en) * | 1997-05-14 | 2000-09-19 | Atherogenics, Inc. | Monoesters of probucol for the treatment of cardiovascular and inflammatory disease |
US6147250A (en) * | 1997-05-14 | 2000-11-14 | Atherogenics, Inc. | Compounds and methods for the inhibition of the expression of VCAM-1 |
Also Published As
Publication number | Publication date |
---|---|
WO2005025492A2 (en) | 2005-03-24 |
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