BRPI0912266B8 - composto derivado de óxido de benzotiofeno, e, composição farmacêutica - Google Patents
composto derivado de óxido de benzotiofeno, e, composição farmacêuticaInfo
- Publication number
- BRPI0912266B8 BRPI0912266B8 BRPI0912266A BRPI0912266A BRPI0912266B8 BR PI0912266 B8 BRPI0912266 B8 BR PI0912266B8 BR PI0912266 A BRPI0912266 A BR PI0912266A BR PI0912266 A BRPI0912266 A BR PI0912266A BR PI0912266 B8 BRPI0912266 B8 BR PI0912266B8
- Authority
- BR
- Brazil
- Prior art keywords
- group
- pharmaceutical composition
- benzothiophene
- salt
- benzothiophene oxide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
derivado de óxido de benzotiofeno ou um sal do mesmo, composto, e, composição farmacêutica. é divulgado um derivado de óxido de benzotiofeno representado pela fórmula geral (em que r1 e r2 são os mesmos ou diferentes e cada um representa um ou mais grupos selecionados entre um átomo de hidrogênio, um átomo de halogênio, um grupo alquila, um grupo arila, um grupo aralquila, um grupo alcóxi, um grupo arilóxi, um grupo alquenila, um grupo amino, um grupo heterocíclico, um grupo amino, um grupo hidroxila, um grupo carboxila, um grupo oxo e similares; r3 representa um grupo alquilamino, um gupo amino, um grupo hidroxila ou similares e m e n são os mesmos ou diferentes e cada um representa um número inteiro de 1-6) ou um sal do mesmo, que é útil como um pró fármaco de um derivado de benzotiofeno ou um sal do mesmo.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008139007 | 2008-05-28 | ||
| JP2008-139007 | 2008-05-28 | ||
| PCT/JP2009/059576 WO2009145171A1 (ja) | 2008-05-28 | 2009-05-26 | 新規なベンゾチオフェンオキシド誘導体またはその塩 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0912266A2 BRPI0912266A2 (pt) | 2015-10-13 |
| BRPI0912266B1 BRPI0912266B1 (pt) | 2019-07-09 |
| BRPI0912266B8 true BRPI0912266B8 (pt) | 2021-05-25 |
Family
ID=41377044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0912266A BRPI0912266B8 (pt) | 2008-05-28 | 2009-05-26 | composto derivado de óxido de benzotiofeno, e, composição farmacêutica |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US8026232B2 (pt) |
| EP (1) | EP2287160B1 (pt) |
| JP (1) | JP5552424B2 (pt) |
| KR (1) | KR101615114B1 (pt) |
| CN (1) | CN102046620B (pt) |
| AU (1) | AU2009252368B2 (pt) |
| BR (1) | BRPI0912266B8 (pt) |
| CA (1) | CA2725307C (pt) |
| CY (1) | CY1115355T1 (pt) |
| DK (1) | DK2287160T3 (pt) |
| ES (1) | ES2465005T3 (pt) |
| HR (1) | HRP20140495T1 (pt) |
| IL (1) | IL209443A (pt) |
| MX (1) | MX2010012787A (pt) |
| NZ (1) | NZ589448A (pt) |
| PL (1) | PL2287160T3 (pt) |
| PT (1) | PT2287160E (pt) |
| SI (1) | SI2287160T1 (pt) |
| WO (1) | WO2009145171A1 (pt) |
| ZA (1) | ZA201008354B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0213393B8 (pt) | 2001-10-19 | 2021-05-25 | Fujifilm Toyama Chemical Co Ltd | derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica |
| CN104159583B (zh) * | 2012-02-22 | 2018-04-13 | 富山化学工业株式会社 | 含有1‑(3‑(2‑(1‑苯并噻吩‑5‑基)乙氧基)丙基)氮杂环丁烷‑3‑醇或其盐的固体药物组合物 |
| JP7176957B2 (ja) * | 2016-12-28 | 2022-11-22 | 富士フイルム富山化学株式会社 | 外用組成物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7049443B2 (en) * | 2001-07-12 | 2006-05-23 | Pharmacia & Upjohn Company | Amide-containing compound having improved solubility and method of improving the solubility of an amide-containing compound |
| BRPI0213393B8 (pt) | 2001-10-19 | 2021-05-25 | Fujifilm Toyama Chemical Co Ltd | derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica |
| SI2389937T1 (sl) * | 2002-06-14 | 2018-10-30 | Toyama Chemical Co., Ltd, | Farmacevtska sestava za izboljšanje možganske funkcije |
| SI2011796T1 (sl) * | 2006-04-26 | 2015-02-27 | Toyama Chemical Co., Ltd. | Induktor nevrogeneze ali terapevtska uäśinkovina proti nevropatiji, vsebujoäśa derivat alkilnega etra ali sol le-tega |
| JP5255441B2 (ja) * | 2006-08-04 | 2013-08-07 | 富山化学工業株式会社 | アルキルエーテル誘導体またはその塩を含有するプロテインキナーゼｃ活性促進剤 |
-
2009
- 2009-05-26 SI SI200930987T patent/SI2287160T1/sl unknown
- 2009-05-26 AU AU2009252368A patent/AU2009252368B2/en active Active
- 2009-05-26 PT PT97546790T patent/PT2287160E/pt unknown
- 2009-05-26 BR BRPI0912266A patent/BRPI0912266B8/pt active IP Right Grant
- 2009-05-26 ES ES09754679.0T patent/ES2465005T3/es active Active
- 2009-05-26 CA CA2725307A patent/CA2725307C/en active Active
- 2009-05-26 WO PCT/JP2009/059576 patent/WO2009145171A1/ja active Application Filing
- 2009-05-26 JP JP2010514481A patent/JP5552424B2/ja active Active
- 2009-05-26 MX MX2010012787A patent/MX2010012787A/es active IP Right Grant
- 2009-05-26 EP EP09754679.0A patent/EP2287160B1/en active Active
- 2009-05-26 PL PL09754679T patent/PL2287160T3/pl unknown
- 2009-05-26 DK DK09754679.0T patent/DK2287160T3/da active
- 2009-05-26 NZ NZ589448A patent/NZ589448A/en unknown
- 2009-05-26 KR KR1020107026524A patent/KR101615114B1/ko active IP Right Grant
- 2009-05-26 US US12/994,837 patent/US8026232B2/en active Active
- 2009-05-26 CN CN200980119501.9A patent/CN102046620B/zh active Active
-
2010
- 2010-11-18 IL IL209443A patent/IL209443A/en active IP Right Grant
- 2010-11-22 ZA ZA2010/08354A patent/ZA201008354B/en unknown
-
2014
- 2014-05-29 HR HRP20140495AT patent/HRP20140495T1/hr unknown
- 2014-07-01 CY CY20141100486T patent/CY1115355T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2287160A1 (en) | 2011-02-23 |
| CN102046620A (zh) | 2011-05-04 |
| WO2009145171A1 (ja) | 2009-12-03 |
| IL209443A (en) | 2014-02-27 |
| MX2010012787A (es) | 2011-02-24 |
| BRPI0912266A2 (pt) | 2015-10-13 |
| JPWO2009145171A1 (ja) | 2011-10-13 |
| PT2287160E (pt) | 2014-06-24 |
| ZA201008354B (en) | 2012-02-29 |
| BRPI0912266B1 (pt) | 2019-07-09 |
| CA2725307A1 (en) | 2009-12-03 |
| EP2287160B1 (en) | 2014-05-07 |
| JP5552424B2 (ja) | 2014-07-16 |
| NZ589448A (en) | 2011-09-30 |
| US8026232B2 (en) | 2011-09-27 |
| CY1115355T1 (el) | 2017-01-04 |
| KR20110010741A (ko) | 2011-02-07 |
| AU2009252368A1 (en) | 2009-12-03 |
| US20110077413A1 (en) | 2011-03-31 |
| AU2009252368B2 (en) | 2013-10-03 |
| CN102046620B (zh) | 2014-04-09 |
| CA2725307C (en) | 2015-12-22 |
| DK2287160T3 (da) | 2014-06-10 |
| KR101615114B1 (ko) | 2016-04-25 |
| SI2287160T1 (sl) | 2014-09-30 |
| EP2287160A4 (en) | 2012-01-04 |
| PL2287160T3 (pl) | 2014-09-30 |
| IL209443A0 (en) | 2011-01-31 |
| ES2465005T3 (es) | 2014-06-04 |
| HRP20140495T1 (hr) | 2014-07-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DOP2011000281A (es) | Derivados de benzofurano | |
| BR112014010644A2 (pt) | novos derivados de aril-quinolina | |
| CY1123154T1 (el) | Παραγοντας ενισχυσης της επιδρασης αποκαταστασης μετα απο νευρικη βλαβη που περιλαμβανει ενα παραγωγο αλκυλαιθερα ή ενα αλας αυτου | |
| EA201690019A1 (ru) | Производное аминотриазина и содержащая его фармацевтическая композиция | |
| BR122019003178B1 (pt) | método de controle de pestes | |
| CY1120682T1 (el) | Ενωσεις για την προστασια κυτταρων | |
| CY1119220T1 (el) | Μονοκυκλικο παραγωγο πυριδινης | |
| BRPI0718966B8 (pt) | composto, composição farmacêutica, inibidor plk1 e agente antitumoral | |
| BR112014006660A2 (pt) | novos derivados de dihidroquinolina-2-ona bicíclicos | |
| CY1115643T1 (el) | Διεγερτης νευρογενεσης ή θεραπευτικος παραγων νευροπαθειας που περιλαμβανει παραγωγα αλκυλ αιθερα ή αλας αυτου | |
| BRPI1011683B8 (pt) | derivados de isoquinolina substituída, suas composições farmacêuticas e seus usos | |
| BR112015015275A2 (pt) | composto heterocíclico substituído por halogênio | |
| BR112013018732A2 (pt) | novos derivados de amida de aril-benzocicloalquila | |
| MY169043A (en) | New dihydroquinoline-2-one derivatives | |
| EA201170096A1 (ru) | Замещенные производные пиримидона | |
| BR112016001979A2 (pt) | composto de tetrazolinona e uso do mesmo | |
| AR080596A1 (es) | Compuestos alquilamido y composiciones farmaceuticas | |
| CO6460743A2 (es) | Derivados de 7-aza-espiro[3.5]nonano-7-carboxilatos, su preparación y su aplicación en terapéutica | |
| BR112017022654A2 (pt) | derivado heterocíclico de 6 membros e composição farmacêutica compreendendo o mesmo | |
| CY1121626T1 (el) | Νεο παραγωγο υδροξαμικου οξεος ή αλας αυτου | |
| CU24030B1 (es) | Nuevos derivados de benzotiadiazepinas, su procedimiento de preparación y composiciones farmacéuticas que los contienen | |
| CO2018010787A2 (es) | Compuesto de griseofulvina | |
| DK2048145T3 (da) | Forstærker af aktiviteten af proteinkinase C indeholdende alkyletherderivat eller et salt deraf | |
| BR112015017740A2 (pt) | composto heterocíclico condensado | |
| CY1117026T1 (el) | Ετεροκυκλικες ενωσεις για αντιμετωπιση ή προληψη διαταραχων που προκαλουνται απο μειωμενη νευροδιαβιβαση σεροτονινης, νορεπινεφρινης ή ντοπαμινης |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 09/07/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 09/07/2019, OBSERVADAS AS CONDICOES LEGAIS |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/05/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |