NO20083641L - Dibenzylaminforbindelser, samt derivater derav - Google Patents

Dibenzylaminforbindelser, samt derivater derav

Info

Publication number
NO20083641L
NO20083641L NO20083641A NO20083641A NO20083641L NO 20083641 L NO20083641 L NO 20083641L NO 20083641 A NO20083641 A NO 20083641A NO 20083641 A NO20083641 A NO 20083641A NO 20083641 L NO20083641 L NO 20083641L
Authority
NO
Norway
Prior art keywords
compounds
derivatives
levels
cholesterol
well
Prior art date
Application number
NO20083641A
Other languages
English (en)
Inventor
David Austen Perry
Bruce Allen Lefker
Chang George
Ravi Shanker Gangipati
Dongxiang Zeng
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20083641L publication Critical patent/NO20083641L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C261/00—Derivatives of cyanic acid
    • C07C261/04—Cyanamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C07D257/06—Five-membered rings with nitrogen atoms directly attached to the ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

Det beskrives dibenzylaminforbindelser og derivater, farmasøytiske sammensetninger innholdende slike forbindelser og anvendelse av slike forbindelser for å forhøye nivået av visse plasmalipider, inkluderende høytetthet lipoprotein-kolesterol og å senke visse andre plasmalipid nivåer så som LDL kolesterol og triglyserider og således behandle sykdommer som forverres ved lave nivåer av HDL kolesterol og/eller nivåer av LDL kolesterol og triglyserider, så som aterosklerose og kardiovaskulære sykdommer i noen pattedyr, inkluderende mennesker.
NO20083641A 2006-03-10 2008-08-22 Dibenzylaminforbindelser, samt derivater derav NO20083641L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78099306P 2006-03-10 2006-03-10
US11/619,277 US7919506B2 (en) 2006-03-10 2007-01-03 Dibenzyl amine compounds and derivatives
PCT/IB2007/000527 WO2007105050A1 (en) 2006-03-10 2007-02-26 Dibenzyl amine compounds and derivatives

Publications (1)

Publication Number Publication Date
NO20083641L true NO20083641L (no) 2008-09-29

Family

ID=38088523

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083641A NO20083641L (no) 2006-03-10 2008-08-22 Dibenzylaminforbindelser, samt derivater derav

Country Status (26)

Country Link
US (1) US7919506B2 (no)
EP (1) EP1996564A1 (no)
JP (1) JP5075843B2 (no)
KR (1) KR101058312B1 (no)
AP (1) AP2008004604A0 (no)
AR (1) AR059803A1 (no)
AU (1) AU2007226261B2 (no)
BR (1) BRPI0709003A2 (no)
CA (2) CA2645294C (no)
CR (1) CR10264A (no)
DO (1) DOP2007000047A (no)
EA (1) EA200801815A1 (no)
EC (1) ECSP088729A (no)
GT (1) GT200700020A (no)
IL (1) IL193571A (no)
MA (1) MA30271B1 (no)
MX (1) MX2008010863A (no)
NL (1) NL2000514C2 (no)
NO (1) NO20083641L (no)
PE (1) PE20080118A1 (no)
RS (1) RS20080410A (no)
SG (1) SG176418A1 (no)
TN (1) TNSN08347A1 (no)
TW (1) TW200738652A (no)
UY (1) UY30196A1 (no)
WO (1) WO2007105050A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8383660B2 (en) * 2006-03-10 2013-02-26 Pfizer Inc. Dibenzyl amine compounds and derivatives
EP2612669A4 (en) 2010-08-31 2014-05-14 Snu R&Db Foundation USING THE FÖTAL REPROGRAMMING OF A PPAR AGONIST
CN103351354B (zh) * 2013-06-09 2015-08-12 西安近代化学研究所 1-甲基-5-氨基四唑合成方法
CN103524445A (zh) * 2013-09-09 2014-01-22 南通市华峰化工有限责任公司 一种1-甲基-5氨基四氮唑的合成生产方法
CN105793243A (zh) * 2013-12-05 2016-07-20 拜耳作物科学股份公司 N-环烷基-n-{[2-(1-取代的环烷基)苯基]亚甲基}-(硫代)甲酰胺衍生物

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Also Published As

Publication number Publication date
DOP2007000047A (es) 2007-09-15
KR20080091861A (ko) 2008-10-14
EP1996564A1 (en) 2008-12-03
SG176418A1 (en) 2011-12-29
US20070213371A1 (en) 2007-09-13
CR10264A (es) 2008-09-23
MX2008010863A (es) 2008-09-03
TNSN08347A1 (fr) 2009-12-29
IL193571A0 (en) 2009-05-04
CA2645294A1 (en) 2007-09-20
PE20080118A1 (es) 2008-02-22
EA200801815A1 (ru) 2009-02-27
CA2645294C (en) 2011-08-30
RS20080410A (en) 2009-09-08
AP2008004604A0 (en) 2008-10-31
JP5075843B2 (ja) 2012-11-21
AR059803A1 (es) 2008-04-30
GT200700020A (es) 2007-11-15
MA30271B1 (fr) 2009-03-02
UY30196A1 (es) 2007-10-31
ECSP088729A (es) 2008-10-31
US7919506B2 (en) 2011-04-05
TW200738652A (en) 2007-10-16
NL2000514C2 (nl) 2009-03-31
CA2717249A1 (en) 2007-09-20
IL193571A (en) 2012-12-31
KR101058312B1 (ko) 2011-08-22
AU2007226261A1 (en) 2007-09-20
WO2007105050A1 (en) 2007-09-20
NL2000514A1 (nl) 2007-09-11
JP2009531312A (ja) 2009-09-03
BRPI0709003A2 (pt) 2011-06-21
AU2007226261B2 (en) 2012-08-16

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