NO20083461L - Genekspresjonsmarkorer for kolorektal cancer-prognose - Google Patents

Genekspresjonsmarkorer for kolorektal cancer-prognose

Info

Publication number
NO20083461L
NO20083461L NO20083461A NO20083461A NO20083461L NO 20083461 L NO20083461 L NO 20083461L NO 20083461 A NO20083461 A NO 20083461A NO 20083461 A NO20083461 A NO 20083461A NO 20083461 L NO20083461 L NO 20083461L
Authority
NO
Norway
Prior art keywords
colorectal cancer
gene expression
cancer prognosis
expression markers
expression
Prior art date
Application number
NO20083461A
Other languages
English (en)
Inventor
Wayne Cowens
Joffre B Baker
Kim Clark
James Hackett
Drew Watson
Soonmyung Paik
Original Assignee
Nsabp Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nsabp Foundation Inc filed Critical Nsabp Foundation Inc
Publication of NO20083461L publication Critical patent/NO20083461L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57446—Specifically defined cancers of stomach or intestine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Fremgangsmåte for å forutse klinisk resultat i et individ som er diagnostisert med kolorektal kreft som omfatter å vise uttrykket av et eller flere av prediktive RNA-transkript eller deres uttrykksprodukter i en biologisk prøve av kreftceller som er tilveiebrakt fra individet.
NO20083461A 2006-01-11 2008-08-08 Genekspresjonsmarkorer for kolorektal cancer-prognose NO20083461L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US75839206P 2006-01-11 2006-01-11
US80027706P 2006-05-12 2006-05-12
US81007706P 2006-05-31 2006-05-31
PCT/US2007/000995 WO2007082099A2 (en) 2006-01-11 2007-01-11 Gene expression markers for colorectal cancer prognosis

Publications (1)

Publication Number Publication Date
NO20083461L true NO20083461L (no) 2008-10-10

Family

ID=38257063

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083461A NO20083461L (no) 2006-01-11 2008-08-08 Genekspresjonsmarkorer for kolorektal cancer-prognose

Country Status (15)

Country Link
US (10) US7695913B2 (no)
EP (9) EP1974058B1 (no)
JP (7) JP5297202B2 (no)
KR (1) KR20090003178A (no)
AU (1) AU2007204826B2 (no)
BR (1) BRPI0706511A2 (no)
CA (1) CA2636984A1 (no)
DK (1) DK1974058T3 (no)
ES (1) ES2491222T3 (no)
HK (1) HK1120089A1 (no)
IL (1) IL192794A (no)
MX (1) MX2008008973A (no)
NO (1) NO20083461L (no)
NZ (7) NZ593227A (no)
WO (1) WO2007082099A2 (no)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1570080A4 (en) 2002-11-15 2006-03-01 Genomic Health Inc GENE EXPRESSION PROFILING OF EGFR-POSITIVE CANCER DISEASE
CA2563074C (en) 2004-04-09 2014-05-20 Genomic Health, Inc. Gene expression markers for predicting response to chemotherapy
EP1974058B1 (en) * 2006-01-11 2014-06-11 Genomic Health, Inc. Gene expression markers for colorectal cancer prognosis
CN103424541B (zh) 2006-05-18 2018-01-30 分子压型学会股份有限公司 确定针对病状的个性化医疗介入的系统和方法
US8768629B2 (en) 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
US20090076734A1 (en) 2007-03-22 2009-03-19 Torres-Roca Javier F Gene Signature for the Prediction of Radiation Therapy Response
US20080234946A1 (en) * 2007-03-22 2008-09-25 University Of South Florida Predictive radiosensitivity network model
DK2140269T3 (da) 2007-03-27 2013-12-16 Immunovia Ab Proteinsignatur/markører til at detektere adenocarcinom
US20090123920A1 (en) * 2007-11-08 2009-05-14 Maher Albitar Jak2 mutations
ES2332167B1 (es) 2007-12-04 2010-10-25 Universidad Autonoma De Madrid Empleo de trefoil factor-family 3 (tff3) en el pronostico de sujetos diagnosticados con cancer colorectal.
WO2009123634A1 (en) * 2008-04-02 2009-10-08 Regents Of The University Of California Systems and methods for predicting response of biological samples
US8067178B2 (en) 2008-03-14 2011-11-29 Genomic Health, Inc. Gene expression markers for prediction of patient response to chemotherapy
NZ589143A (en) 2008-05-14 2012-02-24 Genomic Health Inc Colorectal cancer response prediction based on AREG EREG DUSP6 and SLC26A3 expression levels
US20100029748A1 (en) * 2008-08-04 2010-02-04 Sloan-Kettering Institute For Cancer Research Metastasis Promoting Genes and Proteins
US10359425B2 (en) * 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
US20100221752A2 (en) * 2008-10-06 2010-09-02 Somalogic, Inc. Ovarian Cancer Biomarkers and Uses Thereof
US20110257034A1 (en) * 2008-10-10 2011-10-20 Cornell University Methods for identifying genes which predict disease outcome for patients with colon cancer
US20120041274A1 (en) 2010-01-07 2012-02-16 Myriad Genetics, Incorporated Cancer biomarkers
US8765383B2 (en) * 2009-04-07 2014-07-01 Genomic Health, Inc. Methods of predicting cancer risk using gene expression in premalignant tissue
SG175832A1 (en) * 2009-05-01 2011-12-29 Genomic Health Inc Gene expression profile algorithm and test for likelihood of recurrence of colorectal cancer and response to chemotherapy
TWI513465B (zh) * 2009-06-25 2015-12-21 Regeneron Pharma 以ｄｌｌ４拮抗劑與化學治療劑治療癌症之方法
EP2591126B1 (en) 2010-07-07 2020-12-30 Myriad Genetics, Inc. Gene signatures for cancer prognosis
SG10201508656VA (en) 2010-07-09 2015-11-27 Somalogic Inc Lung cancer biomarkers and uses thereof
EP3556870B9 (en) 2010-07-27 2022-09-28 Genomic Health, Inc. Method for using gene expression to determine prognosis of prostate cancer
AU2011289284B2 (en) 2010-08-13 2015-04-09 Somalogic Operating Co., Inc. Pancreatic cancer biomarkers and uses thereof
WO2012030840A2 (en) 2010-08-30 2012-03-08 Myriad Genetics, Inc. Gene signatures for cancer diagnosis and prognosis
SG188397A1 (en) 2010-09-15 2013-04-30 Almac Diagnostics Ltd Molecular diagnostic test for cancer
AU2012209074A1 (en) 2011-01-25 2013-07-11 Almac Diagnostics Limited Colon cancer gene expression signatures and methods of use
AU2012330817A1 (en) 2011-11-04 2014-05-22 Oslo Universitetssykehus Hf Methods and biomarkers for analysis of colorectal cancer
US20140314662A1 (en) 2011-11-28 2014-10-23 Institucio Catalana De Recerca / Estudis Avancats Methods and kits for the prognosis of colorectal cancer
US10519506B2 (en) 2011-12-22 2019-12-31 Baylor Research Institute Identification of metastasis-specific miRNA and hypomethylation signatures in human colorectal cancer
JP2015503923A (ja) * 2012-01-09 2015-02-05 オスロ ウニヴェルスィテーツスィーケフース ハーエフＯｓｌｏ Ｕｎｉｖｅｒｓｉｔｅｔｓｓｙｋｅｈｕｓ Ｈｆ 結腸直腸癌の解析のための方法およびバイオマーカー
MX351626B (es) 2012-01-31 2017-10-23 Genomic Health Inc Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata.
WO2013150167A2 (es) 2012-04-03 2013-10-10 Servicio Andaluz De Salud Modelo de expresión de microarn como indicador de supervivencia en pacientes de cancer colorrectal metastásico
WO2014077915A1 (en) * 2012-11-14 2014-05-22 Mayo Foundation For Medical Education And Research Methods and materials for identifying malignant skin lesions
EP4190918A1 (en) 2012-11-16 2023-06-07 Myriad Genetics, Inc. Gene signatures for cancer prognosis
ES2475366B1 (es) * 2012-12-10 2015-05-05 Fundación Imdea Alimentación Métodos y kits para el pronóstico del cáncer colorrectal
WO2014159791A1 (en) 2013-03-14 2014-10-02 Abbott Molecular Inc. Materials and methods for assessment of colorectal adenoma
AR096507A1 (es) * 2013-05-30 2016-01-13 Fundació Institució Catalana De Recerca I Estudis Avançats Métodos y kits para el pronóstico del cáncer colorrectal
US10185809B1 (en) * 2013-10-15 2019-01-22 Iqvia Inc. Patient projection methodology
GB201319878D0 (en) * 2013-11-11 2013-12-25 Immunovia Ab Method, Array and use thereof
US20170176441A1 (en) * 2014-03-28 2017-06-22 Applied Proteomics, Inc. Protein biomarker profiles for detecting colorectal tumors
CA2947624A1 (en) 2014-05-13 2015-11-19 Myriad Genetics, Inc. Gene signatures for cancer prognosis
WO2016025717A1 (en) 2014-08-14 2016-02-18 Mayo Foundation For Medical Education And Research Methods and materials for identifying metastatic malignant skin lesions and treating skin cancer
JP7065609B6 (ja) 2014-10-24 2022-06-06 コーニンクレッカ フィリップス エヌ ヴェ 複数の細胞シグナル伝達経路活性を用いる治療応答の医学的予後及び予測
JP7065610B6 (ja) 2014-10-24 2022-06-06 コーニンクレッカ フィリップス エヌ ヴェ 複数の細胞シグナル伝達経路活性を用いる治療応答の医学的予後及び予測
WO2016062891A1 (en) 2014-10-24 2016-04-28 Koninklijke Philips N.V. ASSESSMENT OF TGF-β CELLULAR SIGNALING PATHWAY ACTIVITY USING MATHEMATICAL MODELLING OF TARGET GENE EXPRESSION
WO2016084130A1 (ja) 2014-11-25 2016-06-02 三菱電機株式会社 空圧式アクチュエータ
US20180148789A1 (en) * 2014-12-01 2018-05-31 University Of Southern California Methods for treating and assessing tumor invasion and metastasis
EP3073268A1 (en) * 2015-03-27 2016-09-28 Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts Biomarker panel for diagnosing cancer
JP2018517892A (ja) 2015-04-10 2018-07-05 アプライド プロテオミクス，インク． 結腸直腸癌と進行腺腫を検知するためのタンパク質バイオマーカーパネル
EP3316159A4 (en) * 2015-06-25 2019-08-14 Advanced Telecommunications Research Institute International PREDICTIVE EQUIPMENT BASED ON A SYSTEM ASSOCIATED WITH SEVERAL INSTITUTIONS AND PREDICTION PROGRAM
ES2861400T3 (es) 2015-08-14 2021-10-06 Koninklijke Philips Nv Evaluación de la actividad de la ruta de señalización celular de NFkB usando modelos matemáticos de la expresión de genes diana
WO2017170803A1 (ja) 2016-03-29 2017-10-05 株式会社国際電気通信基礎技術研究所 医薬組成物又は食品組成物、及び有効成分の体内での効果の評価方法
MX2018013815A (es) 2016-05-10 2019-07-04 Mayo Found Medical Education & Res Metodos y materiales para estadificar y tratar cancer de piel.
WO2018165532A1 (en) 2017-03-10 2018-09-13 Baylor Research Institute Methods for diagnosing and treating gastric cancer using mirna expression
WO2018224731A1 (en) * 2017-06-05 2018-12-13 Ls Cancerdiag Oy A method for determining whether a subject is at risk to develop cancer and tools related thereto
EP3461915A1 (en) 2017-10-02 2019-04-03 Koninklijke Philips N.V. Assessment of jak-stat1/2 cellular signaling pathway activity using mathematical modelling of target gene expression
EP3502279A1 (en) 2017-12-20 2019-06-26 Koninklijke Philips N.V. Assessment of mapk-ap 1 cellular signaling pathway activity using mathematical modelling of target gene expression
JP7027179B2 (ja) * 2018-01-24 2022-03-01 キヤノン株式会社 給送回転体、シート給送装置及び画像形成装置
EP3762493A4 (en) 2018-03-08 2021-11-24 University of Notre Dame du Lac SYSTEMS AND METHODS FOR EVALUATING THE MOLECULAR SUBTYPE AND RELIABILITY RISK OF COLON CANCER AND DETERMINING AND ADMINISTERING TREATMENT PROTOCOLS BASED ON THEM
KR102007450B1 (ko) * 2018-05-31 2019-08-05 한국과학기술연구원 대장암 치료제 발굴을 위한 신규 표적 치료 작용점의 스크리닝 방법 및 이를 이용하여 선별한 대장암 치료 예후 바이오마커
EP3886809A4 (en) 2018-11-28 2022-03-30 Genascence Corporation METHODS AND COMPOSITIONS FOR THE TREATMENT OF OSTEOARTHRITIS
WO2020123699A1 (en) * 2018-12-11 2020-06-18 The Trustees Of Columbia University In The City Of New York Compounds and compositions that cause mycn and/or cmyc degradation and methods of use thereof
CN110257518B (zh) * 2019-07-01 2022-08-02 复旦大学附属中山医院 一种用于预测转移性结直肠癌转化治疗疗效的基因集
KR102263984B1 (ko) * 2020-02-21 2021-06-11 재단법인 아산사회복지재단 직장암 환자에서 수술-전 화학방사선치료의 반응을 예측하기 위한 분석방법
KR102535150B1 (ko) * 2020-04-14 2023-05-23 주식회사 베르티스 암의 예후 예측용 조성물
WO2021222220A2 (en) * 2020-04-29 2021-11-04 Freenome Holdings, Inc. Rna markers and methods for identifying colon cell proliferative disorders
GB202010970D0 (en) 2020-07-16 2020-09-02 Immunovia Ab Methods, arrays and uses thereof
CN112322730B (zh) * 2020-10-16 2023-04-18 上海市第一人民医院 预测肿瘤耐药、复发的标志物kifc1及其抑制剂和应用
EP4026918A1 (en) 2021-01-12 2022-07-13 Koninklijke Philips N.V. Prediction of an outcome of a colorectal cancer subject
CN113667673B (zh) * 2021-07-15 2024-02-06 武汉血液中心 一种类孟买血型FUT1 236delG等位基因及其检测方法和应用
KR20230059642A (ko) * 2021-10-26 2023-05-03 사회복지법인 삼성생명공익재단 miRNA를 포함하는 대장암의 치료 및 전이 억제용 조성물 및 이의 용도
WO2024035653A1 (en) * 2022-08-06 2024-02-15 H. Lee Moffitt Cancer Center And Research Institute, Inc. Predictive biomarker in avastin in colon cancer

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020172987A1 (en) * 1998-02-12 2002-11-21 Terstappen Leon W.M.M. Methods and reagents for the rapid and efficient isolation of circulating cancer cells
WO1999064627A2 (en) 1998-06-06 1999-12-16 Genostic Pharma Limited Probes used for genetic profiling
CA2330929A1 (en) * 1998-06-06 1999-12-16 Genostic Pharma Limited Probes used for genetic profiling
WO2000024940A1 (en) 1998-10-28 2000-05-04 Vysis, Inc. Cellular arrays and methods of detecting and using genetic disorder markers
EP0999016B1 (en) * 1998-11-06 2001-07-11 Temco S. R. L. Cutter for cross cutting of webs
US6692916B2 (en) * 1999-06-28 2004-02-17 Source Precision Medicine, Inc. Systems and methods for characterizing a biological condition or agent using precision gene expression profiles
US6960439B2 (en) * 1999-06-28 2005-11-01 Source Precision Medicine, Inc. Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
AU7721500A (en) * 1999-09-29 2001-04-30 Human Genome Sciences, Inc. Colon and colon cancer associated polynucleotides and polypeptides
AU2088801A (en) * 1999-12-10 2001-06-18 Dana-Farber Cancer Institute, Inc. Metastasis genes and uses thereof
US7029677B2 (en) * 2000-01-25 2006-04-18 Nuvelo, Inc. Methods of therapy and diagnosis using immunotargeting of CD84Hy1-expressing cells
WO2001077164A2 (en) 2000-04-06 2001-10-18 Epigenomics Ag Diagnosis of diseases associated with apoptosis by means of assessing the methylation status of genes associated with apoptosis
WO2005000087A2 (en) 2003-06-03 2005-01-06 Chiron Corporation Gene products differentially expressed in cancerous colon cells and their methods of use ii
AU2001280982A1 (en) 2000-08-03 2002-02-18 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer
US20030166064A1 (en) * 2000-08-03 2003-09-04 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer
WO2002012280A2 (en) 2000-08-03 2002-02-14 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer
US20030077568A1 (en) * 2000-09-15 2003-04-24 Gish Kurt C. Methods of diagnosis of colorectal cancer, compositions and methods of screening for colorectal cancer modulators
EP1339872A2 (en) 2000-09-19 2003-09-03 Whitehead Institute For Biomedical Research Genetic markers for tumors
AU2002246519A1 (en) * 2000-11-20 2002-08-06 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer
US20030087818A1 (en) * 2001-02-02 2003-05-08 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer
AU2002311903A1 (en) * 2001-05-09 2002-11-18 University Hospitals Of Cleveland Evaluation of ultraviolet radiation damage to skin using new genemarkers, methods and compositions related thereto
US20030148314A1 (en) * 2001-08-01 2003-08-07 Millennium Pharmaceuticals, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of colon cancer
US7622260B2 (en) * 2001-09-05 2009-11-24 The Brigham And Women's Hospital, Inc. Diagnostic and prognostic tests
KR20040064275A (ko) * 2001-11-09 2004-07-16 소스 프리시전 메디슨, 인코포레이티드 유전자 발현 프로파일을 이용한 질병의 동정, 모니터링,치료 및 생물학적 상태의 확인
WO2003041562A2 (en) * 2001-11-14 2003-05-22 Whitehead Institute For Biomedical Research Molecular cancer diagnosis using tumor gene expression signature
US20030148410A1 (en) * 2001-12-10 2003-08-07 Millennium Pharmaceuticals, Inc. Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of colon cancer
EP1534739A4 (en) * 2002-01-18 2006-05-31 Bristol Myers Squibb Co IDENTIFICATION OF POLYNUCLEOTIDES AND POLYPEPTIDES FOR PREDICTING THE ACTIVITY OF COMPOUNDS THAT INTERACT WITH TYROSINE KINASE PROTEINS AND / OR TYROSINE KINASE PROTEIN PATHWAYS
US7955800B2 (en) * 2002-06-25 2011-06-07 Advpharma Inc. Metastasis-associated gene profiling for identification of tumor tissue, subtyping, and prediction of prognosis of patients
US20040053317A1 (en) * 2002-09-10 2004-03-18 Sidney Kimmel Cancer Center Gene segregation and biological sample classification methods
AU2003304203A1 (en) 2002-10-29 2005-01-04 Pharmacia Corporation Differentially expressed genes involved in cancer, the polypeptides encoded thereby, and methods of using the same
EP1597391B1 (en) * 2003-02-20 2008-10-29 Genomic Health, Inc. Use of intronic rna to measure gene expression
WO2005008213A2 (en) 2003-07-10 2005-01-27 Genomic Health, Inc. Expression profile algorithm and test for cancer prognosis
US20050014165A1 (en) * 2003-07-18 2005-01-20 California Pacific Medical Center Biomarker panel for colorectal cancer
WO2005015236A2 (en) 2003-07-18 2005-02-17 Roche Diagnostics Gmbh A method for predicting the progression of adenocarcinoma
WO2005012875A2 (en) * 2003-07-29 2005-02-10 Bristol-Myers Squibb Company Biomarkers of cyclin-dependent kinase modulation
EP1522594A3 (en) 2003-10-06 2005-06-22 Bayer HealthCare AG Methods and kits for investigating cancer
WO2005076005A2 (en) 2004-01-30 2005-08-18 Medizinische Universität Wien A method for classifying a tumor cell sample based upon differential expression of at least two genes
US20060195266A1 (en) * 2005-02-25 2006-08-31 Yeatman Timothy J Methods for predicting cancer outcome and gene signatures for use therein
WO2005100593A1 (en) 2004-04-16 2005-10-27 Monash University A method for monitoring the progress of cancer
CA2574447A1 (en) 2004-07-15 2006-01-26 University Of Utah Research Foundation Housekeeping genes and methods for identifying the same
US20060183893A1 (en) 2005-01-25 2006-08-17 North Don A Nucleic acids for apoptosis of cancer cells
WO2006110581A2 (en) 2005-04-07 2006-10-19 Novartis Vaccines And Diagnostics Inc. Cancer-related genes
CA2612021A1 (en) * 2005-06-13 2006-12-28 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
US20090299640A1 (en) 2005-11-23 2009-12-03 University Of Utah Research Foundation Methods and Compositions Involving Intrinsic Genes
WO2007070621A2 (en) 2005-12-13 2007-06-21 Children's Medical Center Corporation Prognosis indicators for solid human tumors
NZ544432A (en) 2005-12-23 2009-07-31 Pacific Edge Biotechnology Ltd Prognosis prediction for colorectal cancer using a prognositc signature comprising markers ME2 and FAS
EP1974058B1 (en) 2006-01-11 2014-06-11 Genomic Health, Inc. Gene expression markers for colorectal cancer prognosis
US20100009905A1 (en) 2006-03-24 2010-01-14 Macina Roberto A Compositions and Methods for Detection, Prognosis and Treatment of Colon Cancer
CA2680591A1 (en) * 2007-03-15 2008-09-25 Genomic Health, Inc. Gene expression markers for prediction of patient response to chemotherapy
US8067178B2 (en) * 2008-03-14 2011-11-29 Genomic Health, Inc. Gene expression markers for prediction of patient response to chemotherapy
US8765383B2 (en) * 2009-04-07 2014-07-01 Genomic Health, Inc. Methods of predicting cancer risk using gene expression in premalignant tissue
SG175832A1 (en) * 2009-05-01 2011-12-29 Genomic Health Inc Gene expression profile algorithm and test for likelihood of recurrence of colorectal cancer and response to chemotherapy

Also Published As

Publication number Publication date
US20110039269A1 (en) 2011-02-17
EP2412823B1 (en) 2014-09-03
MX2008008973A (es) 2008-11-26
EP2412821B1 (en) 2014-09-17
JP2013176398A (ja) 2013-09-09
US8153380B2 (en) 2012-04-10
JP5486717B2 (ja) 2014-05-07
AU2007204826B2 (en) 2013-01-10
US8153378B2 (en) 2012-04-10
JP2013074894A (ja) 2013-04-25
EP2412821A1 (en) 2012-02-01
EP2412824A1 (en) 2012-02-01
JP2013215201A (ja) 2013-10-24
EP2412820A1 (en) 2012-02-01
EP2377950B1 (en) 2014-09-17
BRPI0706511A2 (pt) 2011-03-29
AU2007204826A1 (en) 2007-07-19
US20120171688A1 (en) 2012-07-05
US8367345B2 (en) 2013-02-05
JP2013226151A (ja) 2013-11-07
JP5486718B2 (ja) 2014-05-07
US20100190173A1 (en) 2010-07-29
US20110111421A1 (en) 2011-05-12
IL192794A (en) 2013-07-31
NZ593229A (en) 2012-10-26
EP1974058A2 (en) 2008-10-01
EP2407553A1 (en) 2012-01-18
EP2377950A1 (en) 2011-10-19
US8026060B2 (en) 2011-09-27
WO2007082099A2 (en) 2007-07-19
US7695913B2 (en) 2010-04-13
EP2412822A1 (en) 2012-02-01
EP2412824B1 (en) 2014-10-08
IL192794A0 (en) 2009-02-11
JP2013226150A (ja) 2013-11-07
HK1120089A1 (en) 2009-03-20
JP2009523028A (ja) 2009-06-18
NZ593227A (en) 2012-10-26
US20110039270A1 (en) 2011-02-17
US20110039272A1 (en) 2011-02-17
EP2400036A1 (en) 2011-12-28
WO2007082099A3 (en) 2008-01-17
US8273537B2 (en) 2012-09-25
US20110097759A1 (en) 2011-04-28
CA2636984A1 (en) 2007-07-19
US8029995B2 (en) 2011-10-04
US20090291434A1 (en) 2009-11-26
NZ569788A (en) 2011-08-26
US20110039271A1 (en) 2011-02-17
EP1974058B1 (en) 2014-06-11
US20130102492A1 (en) 2013-04-25
EP2412823A1 (en) 2012-02-01
ES2491222T3 (es) 2014-09-05
JP5486719B2 (ja) 2014-05-07
DK1974058T3 (da) 2014-09-01
JP5486720B2 (ja) 2014-05-07
KR20090003178A (ko) 2009-01-09
NZ593224A (en) 2012-10-26
NZ593226A (en) 2012-10-26
US8153379B2 (en) 2012-04-10
NZ593225A (en) 2012-10-26
US8198024B2 (en) 2012-06-12
JP2013223503A (ja) 2013-10-31
JP5297202B2 (ja) 2013-09-25
JP5486664B2 (ja) 2014-05-07
NZ593228A (en) 2012-10-26

Similar Documents

Publication Publication Date Title
NO20083461L (no) Genekspresjonsmarkorer for kolorektal cancer-prognose
Hong et al. DNA methylation-based age prediction from saliva: High age predictability by combination of 7 CpG markers
WO2008115419A3 (en) Gene expression markers for prediction of patient response to chemotherapy
MX2011011571A (es) Algoritmo de perfil de expresion genica y prueba para probabilidad de recidiva de cancer colorrectal y respuesta a la quimioterapia.
WO2009113779A3 (ko) Ｓｎｐ 어레이를 이용한 염색체, 유전자, 또는 특정 뉴클레오티드 서열의 카피 수 측정방법
BRPI0816393A2 (pt) Método para determinar o número de cópias relativo de uma sequência de polinucleotídeo alvo em um genoma de um indivíduo
MX2018011725A (es) Metodo para emplear expresion genica para determinar pronostico de cancer de prostata.
WO2011056489A3 (en) Diagnostic methods for determining prognosis of non-small cell lung cancer
WO2008030845A8 (en) Methods of predicting distant metastasis of lymph node-negative primary breast cancer using biological pathway gene expression analysis
ATE526333T1 (de) Reagentien zum nachweis von hypochloriger säure
BR112012030813A2 (pt) "métodos e kits para detecção in situ de sequências de nucleotídeo"
WO2009055823A3 (en) Method to predict responsiveness of breast cancer to polyaminetype chemotherapy
BRPI0821698A2 (pt) Método para manipular, isolar, detectar ou amplificar um ácido nucleico alvo em uma amostra por hibridização com um conjugado de oligonucleotídeo-oligocátion.
DK2021794T3 (da) Anvendelse af protein S100A 12 som en markør for colorektal cancer
Langevin et al. Novel DNA methylation targets in oral rinse samples predict survival of patients with oral squamous cell carcinoma
EA201291228A1 (ru) Биомаркер для детекции высокогорной адаптации и высокогорного отека легких
MX2013008252A (es) Firma de pronostico para la recurrencia de cancer colorrectal.
WO2012106711A3 (en) A method for detecting chromosome structure and gene expression simultaneously in single cells
WO2011008814A3 (en) Multiplexed measurement of exogenous and endogenous dna
BR112013004044A2 (pt) composições e métodos para quantificação de uma sequência de ácido nucleico em uma amostra.
WO2008122447A3 (en) Dna methylation assay for the diagnosis or prognosis of medical conditions
WO2010077288A3 (en) Methods for identifying differences in alternative splicing between two rna samples
WO2009086000A3 (en) Biomarkers for trichogenicity
WO2010030167A3 (en) Method of detection and diagnosis of oral and nasopharyngeal cancers
BRPI0507392A (pt) método e kit para determinar a possibilidade de metástase de cáncer em um indivìduo

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application