NO20082610L - Trihydrokloridformer av et dihydropteridonderivat og metoder for fremstilling - Google Patents

Trihydrokloridformer av et dihydropteridonderivat og metoder for fremstilling

Info

Publication number
NO20082610L
NO20082610L NO20082610A NO20082610A NO20082610L NO 20082610 L NO20082610 L NO 20082610L NO 20082610 A NO20082610 A NO 20082610A NO 20082610 A NO20082610 A NO 20082610A NO 20082610 L NO20082610 L NO 20082610L
Authority
NO
Norway
Prior art keywords
preparation
derivative
dihydropteridone
methods
trihydrochloride
Prior art date
Application number
NO20082610A
Other languages
English (en)
Norwegian (no)
Inventor
Guenter Linz
Rolf Schmid
Matthias Grauert
Peter Sieger
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of NO20082610L publication Critical patent/NO20082610L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
NO20082610A 2006-02-08 2008-06-04 Trihydrokloridformer av et dihydropteridonderivat og metoder for fremstilling NO20082610L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06101414 2006-02-08
PCT/EP2007/051139 WO2007090844A1 (en) 2006-02-08 2007-02-07 Trihydrochloride forms of a dihydropteridinone derivative and processes for preparation

Publications (1)

Publication Number Publication Date
NO20082610L true NO20082610L (no) 2008-08-26

Family

ID=38008126

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082610A NO20082610L (no) 2006-02-08 2008-06-04 Trihydrokloridformer av et dihydropteridonderivat og metoder for fremstilling

Country Status (22)

Country Link
US (3) US7439358B2 (zh)
EP (2) EP2543669A3 (zh)
JP (1) JP5134552B2 (zh)
KR (2) KR101445114B1 (zh)
CN (2) CN101379064B (zh)
AR (1) AR059349A1 (zh)
AU (1) AU2007213752B2 (zh)
BR (1) BRPI0707604A8 (zh)
CA (1) CA2635834C (zh)
EA (2) EA015389B1 (zh)
EC (1) ECSP088589A (zh)
HK (2) HK1127772A1 (zh)
IL (2) IL193217A (zh)
NO (1) NO20082610L (zh)
NZ (2) NZ570987A (zh)
PE (2) PE20110100A1 (zh)
SG (2) SG10201404755SA (zh)
TW (1) TW200738716A (zh)
UA (2) UA101060C2 (zh)
UY (1) UY30136A1 (zh)
WO (1) WO2007090844A1 (zh)
ZA (1) ZA200804587B (zh)

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US8546566B2 (en) * 2010-10-12 2013-10-01 Boehringer Ingelheim International Gmbh Process for manufacturing dihydropteridinones and intermediates thereof
US9358233B2 (en) 2010-11-29 2016-06-07 Boehringer Ingelheim International Gmbh Method for treating acute myeloid leukemia
US20130131069A1 (en) 2011-05-13 2013-05-23 Boehringer Ingelheim International Gmbh Method for treatment of solid malignancies including advanced or metastatic solid malignancies
US9370535B2 (en) * 2011-05-17 2016-06-21 Boehringer Ingelheim International Gmbh Method for treatment of advanced solid tumors
US20140154304A1 (en) 2012-11-30 2014-06-05 Boehringer Ingelheim International Gmbh Combination therapy with volasertib
JP2016525532A (ja) 2013-07-26 2016-08-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 骨髄異形成症候群の処置
CN105407893A (zh) * 2013-07-26 2016-03-16 勃林格殷格翰国际有限公司 伏拉塞替与地西他滨组合用于急性骨髓性白血病和骨髓增生异常综合征的治疗ii
CN104003989B (zh) * 2014-05-26 2015-11-11 苏州明锐医药科技有限公司 伏拉塞替及其中间体的制备方法
US9867831B2 (en) 2014-10-01 2018-01-16 Boehringer Ingelheim International Gmbh Combination treatment of acute myeloid leukemia and myelodysplastic syndrome
CN105646398B (zh) * 2014-12-05 2018-09-07 上海医药工业研究院 N-((1r,4r)-4-(4-(环丙基甲基)哌嗪-1-基)环己基)乙酰胺的制备方法
WO2016206619A1 (zh) * 2015-06-26 2016-12-29 苏州晶云药物科技有限公司 Volasertib及其三盐酸盐的新晶型
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Also Published As

Publication number Publication date
KR101462879B1 (ko) 2014-11-18
HK1158628A1 (zh) 2012-07-20
AU2007213752A1 (en) 2007-08-16
SG169397A1 (en) 2011-03-30
EA201100638A1 (ru) 2011-10-31
US20090030004A1 (en) 2009-01-29
CN102093360B (zh) 2014-11-05
CA2635834A1 (en) 2007-08-16
US7439358B2 (en) 2008-10-21
AR059349A1 (es) 2008-03-26
EP2543669A2 (en) 2013-01-09
JP5134552B2 (ja) 2013-01-30
KR101445114B1 (ko) 2014-09-29
JP2009526017A (ja) 2009-07-16
KR20080093068A (ko) 2008-10-17
UA95625C2 (ru) 2011-08-25
BRPI0707604A8 (pt) 2017-12-26
WO2007090844A1 (en) 2007-08-16
IL193217A (en) 2017-06-29
BRPI0707604A2 (pt) 2011-05-10
US20070203146A1 (en) 2007-08-30
US8664222B2 (en) 2014-03-04
WO2007090844A8 (en) 2007-10-11
IL193217A0 (en) 2009-02-11
NZ606264A (en) 2014-08-29
US20120214995A1 (en) 2012-08-23
CA2635834C (en) 2014-10-21
EA200801769A1 (ru) 2009-02-27
KR20140082837A (ko) 2014-07-02
AU2007213752B2 (en) 2013-01-17
TW200738716A (en) 2007-10-16
IL236736A0 (en) 2015-02-26
US8188086B2 (en) 2012-05-29
PE20071248A1 (es) 2008-01-15
EA018663B1 (ru) 2013-09-30
HK1127772A1 (en) 2009-10-09
CN101379064A (zh) 2009-03-04
UA101060C2 (ru) 2013-02-25
CN101379064B (zh) 2012-01-25
SG10201404755SA (en) 2014-10-30
EP2543669A3 (en) 2013-05-15
UY30136A1 (es) 2007-09-28
EP1984367A1 (en) 2008-10-29
ECSP088589A (es) 2008-07-30
NZ570987A (en) 2011-09-30
PE20110100A1 (es) 2011-02-18
ZA200804587B (en) 2009-04-29
EA015389B1 (ru) 2011-08-30
CN102093360A (zh) 2011-06-15

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