NO20081369L - Fenyl- og pyridinyl-1,2,4-oksadiazolonderivater, fremgangsmate for deres fremstilling og deres anvendelse som farmasoytika - Google Patents
Fenyl- og pyridinyl-1,2,4-oksadiazolonderivater, fremgangsmate for deres fremstilling og deres anvendelse som farmasoytikaInfo
- Publication number
- NO20081369L NO20081369L NO20081369A NO20081369A NO20081369L NO 20081369 L NO20081369 L NO 20081369L NO 20081369 A NO20081369 A NO 20081369A NO 20081369 A NO20081369 A NO 20081369A NO 20081369 L NO20081369 L NO 20081369L
- Authority
- NO
- Norway
- Prior art keywords
- disorders
- phenyl
- processes
- pyridinyl
- pharmaceuticals
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- ZJOUMXIJEUQGKJ-UHFFFAOYSA-N 5-pyridin-2-yl-1,2,4-oxadiazol-3-one Chemical class O1NC(=O)N=C1C1=CC=CC=N1 ZJOUMXIJEUQGKJ-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- INVHTFJJZGBKTM-UHFFFAOYSA-N 5-phenyl-1,2,4-oxadiazol-3-one Chemical class OC1=NOC(C=2C=CC=CC=2)=N1 INVHTFJJZGBKTM-UHFFFAOYSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 206010022489 Insulin Resistance Diseases 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000003210 demyelinating effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000004129 fatty acid metabolism Effects 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 210000001428 peripheral nervous system Anatomy 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Virology (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05021277 | 2005-09-29 | ||
| PCT/EP2006/009303 WO2007039177A2 (en) | 2005-09-29 | 2006-09-26 | Phenyl- and pyridinyl- 1, 2 , 4 - oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20081369L true NO20081369L (no) | 2008-05-28 |
Family
ID=35788653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20081369A NO20081369L (no) | 2005-09-29 | 2008-03-14 | Fenyl- og pyridinyl-1,2,4-oksadiazolonderivater, fremgangsmate for deres fremstilling og deres anvendelse som farmasoytika |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7709481B2 (https=) |
| EP (1) | EP1931337B1 (https=) |
| JP (1) | JP2009509988A (https=) |
| KR (1) | KR20080048504A (https=) |
| CN (1) | CN101272784A (https=) |
| AR (1) | AR056095A1 (https=) |
| AU (1) | AU2006299091A1 (https=) |
| BR (1) | BRPI0617207A2 (https=) |
| CA (1) | CA2624102A1 (https=) |
| CR (1) | CR9785A (https=) |
| DO (1) | DOP2006000203A (https=) |
| EC (1) | ECSP088322A (https=) |
| IL (1) | IL190231A0 (https=) |
| MA (1) | MA29805B1 (https=) |
| NO (1) | NO20081369L (https=) |
| NZ (1) | NZ566877A (https=) |
| PE (1) | PE20070620A1 (https=) |
| RU (1) | RU2008112198A (https=) |
| TN (1) | TNSN08148A1 (https=) |
| TW (1) | TW200806658A (https=) |
| UY (1) | UY29831A1 (https=) |
| WO (1) | WO2007039177A2 (https=) |
| ZA (1) | ZA200801629B (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7638541B2 (en) | 2006-12-28 | 2009-12-29 | Metabolex Inc. | 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine |
| AU2008279447A1 (en) | 2007-07-19 | 2009-01-29 | Metabolex, Inc. | N-azacyclic substituted pyrrole, pyrazole, imidazole, triazole and tetrazole derivatives as agonists of the RUP3 or GPR119 receptor for the treatment of diabetes and metabolic disorders |
| AU2009231906A1 (en) * | 2008-03-31 | 2009-10-08 | Metabolex, Inc. | Oxymethylene aryl compounds and uses thereof |
| BRPI0920767B1 (pt) * | 2008-10-01 | 2018-07-17 | Bayer Intellectual Property Gmbh | tiazóis substituídos por heterociclila como agentes protetores de cultura, seus usos e seus processos de preparação, composições e seu processo de preparação, e método para combate a fungos nocivos fitopatogênicos |
| BRPI0923366A2 (pt) | 2008-12-11 | 2019-09-24 | Bayer Cropscience Ag | éteres e hodrazonas de oxima de tiazolila como agentes protetors de culturas. |
| EP2198710A1 (de) | 2008-12-19 | 2010-06-23 | Bayer CropScience AG | Verwendung von 5-Pyridin-4yl-(1,3)Thiazole zur Bekämpfung phytopathogener Pilze |
| NZ596467A (en) * | 2009-06-05 | 2014-01-31 | Pfizer | L- ( piperidin-4-yl) -pyrazole derivatives as gpr 119 modulators |
| JP5909185B2 (ja) | 2009-10-01 | 2016-04-26 | シマベイ セラピューティクス, インコーポレーテッド | 置換テトラゾール−1−イルフェノキシメチルチアゾール−2−イルピペリジニルピリミジン塩 |
| NZ599099A (en) | 2009-10-08 | 2013-05-31 | Sanofi Sa | Phenyloxadiazole derivatives as pgds inhibitors |
| JP5960683B2 (ja) | 2010-04-28 | 2016-08-02 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH | 殺真菌剤としてのケトヘテロアリールピペリジンおよび−ピペラジン誘導体 |
| JP5847813B2 (ja) | 2010-06-23 | 2016-01-27 | シマベイ セラピューティクス, インコーポレーテッド | 5−エチル−2−{4−[4−(4−テトラゾル−1−イル−フェノキシメチル)−チアゾール−2−イル]−ピペリジン−1−イル}−ピリミジンの組成物 |
| EP2532233A1 (en) | 2011-06-07 | 2012-12-12 | Bayer CropScience AG | Active compound combinations |
| SI2841437T1 (sl) | 2012-04-26 | 2017-09-29 | Bristol-Myers Squibb Company | Derivati imidazotiadiazola in imidazopirazina kot proteazno aktivirani receptor 4 (PAR4) inhibitorji za zdravljenje agregacije trombocitov |
| EP2855489B1 (en) | 2012-04-26 | 2017-01-04 | Bristol-Myers Squibb Company | Imidazothiadiazole and imidazopyridazine derivatives as protease activated receptor 4 (par4) inhibitors for treating platelet aggregation |
| SG11201406759YA (en) | 2012-04-26 | 2014-11-27 | Bristol Myers Squibb Co | Imidazothiadiazole derivatives as protease activated receptor 4 (par4) inhibitors for treating platelet aggregation |
| AU2017305392A1 (en) | 2016-08-03 | 2019-02-21 | Cymabay Therapeutics, Inc. | Oxymethylene aryl compounds for treating inflammatory gastrointestinal diseases or gastrointestinal conditions |
Family Cites Families (95)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5783593A (en) | 1993-11-04 | 1998-07-21 | Abbott Laboratories | Inhibitors of squalene synthetase and protein farnesyltransferase |
| US5641796A (en) * | 1994-11-01 | 1997-06-24 | Eli Lilly And Company | Oral hypoglycemic agents |
| AU2381397A (en) | 1996-04-19 | 1997-11-12 | Novo Nordisk A/S | Modulators of molecules with phosphotyrosine recognition units |
| ES2199366T3 (es) | 1996-12-31 | 2004-02-16 | Dr. Reddy's Laboratories Ltd. | Compuestos heterociclicos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen y su uso en el tratamiento de diabetes y enfermedades relacionadas. |
| JP4253126B2 (ja) | 1998-01-29 | 2009-04-08 | アムジェン インコーポレイテッド | Ppar−ガンマ調節剤 |
| US6221897B1 (en) | 1998-06-10 | 2001-04-24 | Aventis Pharma Deutschland Gmbh | Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use |
| DE19845405C2 (de) | 1998-10-02 | 2000-07-13 | Aventis Pharma Gmbh | Arylsubstituierte Propanolaminderivate und deren Verwendung |
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-
2006
- 2006-09-26 CA CA002624102A patent/CA2624102A1/en not_active Abandoned
- 2006-09-26 JP JP2008532647A patent/JP2009509988A/ja not_active Abandoned
- 2006-09-26 EP EP06792251.8A patent/EP1931337B1/en active Active
- 2006-09-26 KR KR1020087007393A patent/KR20080048504A/ko not_active Withdrawn
- 2006-09-26 WO PCT/EP2006/009303 patent/WO2007039177A2/en not_active Ceased
- 2006-09-26 AU AU2006299091A patent/AU2006299091A1/en not_active Abandoned
- 2006-09-26 RU RU2008112198/04A patent/RU2008112198A/ru not_active Application Discontinuation
- 2006-09-26 BR BRPI0617207-5A patent/BRPI0617207A2/pt not_active IP Right Cessation
- 2006-09-26 NZ NZ566877A patent/NZ566877A/en not_active IP Right Cessation
- 2006-09-26 CN CNA2006800359361A patent/CN101272784A/zh active Pending
- 2006-09-27 TW TW095135658A patent/TW200806658A/zh unknown
- 2006-09-27 DO DO2006000203A patent/DOP2006000203A/es unknown
- 2006-09-27 AR ARP060104223A patent/AR056095A1/es not_active Application Discontinuation
- 2006-09-27 PE PE2006001170A patent/PE20070620A1/es not_active Application Discontinuation
- 2006-09-29 UY UY29831A patent/UY29831A1/es not_active Application Discontinuation
-
2008
- 2008-02-19 ZA ZA200801629A patent/ZA200801629B/xx unknown
- 2008-02-29 CR CR9785A patent/CR9785A/es not_active Application Discontinuation
- 2008-03-14 NO NO20081369A patent/NO20081369L/no not_active Application Discontinuation
- 2008-03-17 IL IL190231A patent/IL190231A0/en unknown
- 2008-03-24 MA MA30781A patent/MA29805B1/fr unknown
- 2008-03-26 US US12/055,780 patent/US7709481B2/en not_active Expired - Fee Related
- 2008-03-27 EC EC2008008322A patent/ECSP088322A/es unknown
- 2008-03-28 TN TNP2008000148A patent/TNSN08148A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| UY29831A1 (es) | 2007-04-30 |
| ECSP088322A (es) | 2008-04-28 |
| EP1931337B1 (en) | 2013-10-23 |
| US7709481B2 (en) | 2010-05-04 |
| WO2007039177A2 (en) | 2007-04-12 |
| MA29805B1 (fr) | 2008-09-01 |
| WO2007039177B1 (en) | 2007-11-01 |
| RU2008112198A (ru) | 2009-10-10 |
| CA2624102A1 (en) | 2007-04-12 |
| PE20070620A1 (es) | 2007-07-10 |
| EP1931337A2 (en) | 2008-06-18 |
| CN101272784A (zh) | 2008-09-24 |
| CR9785A (es) | 2008-05-21 |
| NZ566877A (en) | 2010-05-28 |
| AU2006299091A1 (en) | 2007-04-12 |
| TW200806658A (en) | 2008-02-01 |
| WO2007039177A3 (en) | 2007-09-07 |
| US20080261979A1 (en) | 2008-10-23 |
| DOP2006000203A (es) | 2007-06-30 |
| IL190231A0 (en) | 2008-11-03 |
| JP2009509988A (ja) | 2009-03-12 |
| AR056095A1 (es) | 2007-09-19 |
| ZA200801629B (en) | 2009-03-25 |
| TNSN08148A1 (en) | 2009-07-14 |
| BRPI0617207A2 (pt) | 2011-07-19 |
| KR20080048504A (ko) | 2008-06-02 |
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