NO20081370L - Fenyl-[1,2,4]-okadiazol-5-on-derivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika - Google Patents

Fenyl-[1,2,4]-okadiazol-5-on-derivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika

Info

Publication number
NO20081370L
NO20081370L NO20081370A NO20081370A NO20081370L NO 20081370 L NO20081370 L NO 20081370L NO 20081370 A NO20081370 A NO 20081370A NO 20081370 A NO20081370 A NO 20081370A NO 20081370 L NO20081370 L NO 20081370L
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Norway
Prior art keywords
phenyl
disorders
derivatives
processes
phenyl group
Prior art date
Application number
NO20081370A
Other languages
English (en)
Inventor
Patrick Bernardelli
Stefanie Keil
Matthias Urmann
Hans Matter
Wolfgang Wendler
Maike Glien
Karen Chandross
Lan Lee
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Sanofi Aventis
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35809809&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20081370(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of NO20081370L publication Critical patent/NO20081370L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
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    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms
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    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical Kinetics & Catalysis (AREA)
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  • Diabetes (AREA)
  • Hematology (AREA)
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  • Child & Adolescent Psychology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
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Abstract

Foreliggende oppfinnelse angår fenyl-[l,2,4]-oksadiazol-5-on-derivater med fenyl-gruppe i alle deres stereoisomere former og blandinger i et hvilket som helst forhold og deres fysiologisk akseptable salter og tautomere former som viser PPAR5-agonist-aktivitet. Det som er beskrevet er forbindelser med formel I hvori radikalene er som definert og deres fysiologisk akseptable salter og fremgangsmåter for deres fremstillinger. Forbindelsene er egnet for behandling og/eller hindring av forstyrrelser vedrørende fettsyremetabolismen og glukoseutnyttingsforstyrrelser så vel som forstyrrelser hvori insulinresistens er involvert og demyelinerende og andre neurodegenerative forstyrrelser i det sentrale og periferale nervesystemet.
NO20081370A 2005-09-29 2008-03-14 Fenyl-[1,2,4]-okadiazol-5-on-derivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika NO20081370L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05021235 2005-09-29
PCT/EP2006/009304 WO2007039178A2 (en) 2005-09-29 2006-09-26 Phenyl-[1,2,4]-oxadiazol-5-one derivatives with phenyl group, processes for their preparation and their use as pharmaceuticals

Publications (1)

Publication Number Publication Date
NO20081370L true NO20081370L (no) 2008-06-17

Family

ID=35809809

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20081367A NO20081367L (no) 2005-09-29 2008-03-14 Fenyl- og pyridyl-1,2,4-oksadiazolonderivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika
NO20081370A NO20081370L (no) 2005-09-29 2008-03-14 Fenyl-[1,2,4]-okadiazol-5-on-derivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20081367A NO20081367L (no) 2005-09-29 2008-03-14 Fenyl- og pyridyl-1,2,4-oksadiazolonderivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika

Country Status (31)

Country Link
US (3) US7834030B2 (no)
EP (2) EP1934206B1 (no)
JP (2) JP2009509986A (no)
KR (2) KR20080048520A (no)
CN (2) CN101273036A (no)
AR (2) AR056203A1 (no)
AT (1) ATE537167T1 (no)
AU (2) AU2006299086A1 (no)
BR (2) BRPI0616465A2 (no)
CA (2) CA2624093A1 (no)
CR (1) CR9784A (no)
CY (1) CY1113376T1 (no)
DK (1) DK1931660T3 (no)
DO (2) DOP2006000204A (no)
EC (1) ECSP088323A (no)
ES (1) ES2392181T3 (no)
IL (2) IL190228A0 (no)
MA (2) MA29804B1 (no)
MY (2) MY148982A (no)
NO (2) NO20081367L (no)
NZ (2) NZ566878A (no)
PE (2) PE20070545A1 (no)
PL (1) PL1931660T3 (no)
PT (1) PT1931660E (no)
RU (2) RU2008112202A (no)
SI (1) SI1931660T1 (no)
TN (1) TNSN08145A1 (no)
TW (2) TW200811154A (no)
UY (2) UY29829A1 (no)
WO (2) WO2007039178A2 (no)
ZA (1) ZA200801630B (no)

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JP6055817B2 (ja) 2011-05-12 2016-12-27 バイオノミックス リミテッド ナフチリジンの調製方法
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
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