NO20054380L - Arylsykloalkylderivater med forgrenede sidekjeder som PPAR-reseptormodulatorer, deres fremstilling og deres anvendelse som legemiddel - Google Patents
Arylsykloalkylderivater med forgrenede sidekjeder som PPAR-reseptormodulatorer, deres fremstilling og deres anvendelse som legemiddelInfo
- Publication number
- NO20054380L NO20054380L NO20054380A NO20054380A NO20054380L NO 20054380 L NO20054380 L NO 20054380L NO 20054380 A NO20054380 A NO 20054380A NO 20054380 A NO20054380 A NO 20054380A NO 20054380 L NO20054380 L NO 20054380L
- Authority
- NO
- Norway
- Prior art keywords
- arylic
- preparation
- side chains
- branched side
- drug
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
- C07C275/10—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Abstract
Det beskrives arylsykloalkylderivater med forgrenede sidekjeder, videre beskrives deres fysiologisk godtakbare salter og fysiologisk funksjonelle derivater. Det beskrives forbindelser med formel (1) der gruppene er definert som angitt i beskrivelsen i tillegg til deres fysiologisk godtakbare salter, og det beskrives videre en fremgangsmåte for deres fremstilling. Forbindelsene er egnet for terapi og/eller prevensjon av forstyrrelser i fettsyremetabohsmen og forstyrrelser i glukoseutnyttelsen i tillegg til forstyrrelser der insulinresistens spiller en rolle.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10308352A DE10308352A1 (de) | 2003-02-27 | 2003-02-27 | Arylcycloalkylderivate mit verzweigten Seitenketten, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel |
PCT/EP2004/001583 WO2004076402A1 (de) | 2003-02-27 | 2004-02-19 | Arylcycloalkylderivate mit verzweigten seitenketten als ppar rezeptor modulatoren, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20054380L true NO20054380L (no) | 2005-09-21 |
Family
ID=32841932
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20054380A NO20054380L (no) | 2003-02-27 | 2005-09-21 | Arylsykloalkylderivater med forgrenede sidekjeder som PPAR-reseptormodulatorer, deres fremstilling og deres anvendelse som legemiddel |
Country Status (22)
Country | Link |
---|---|
US (1) | US7220876B2 (no) |
EP (1) | EP1601643B1 (no) |
JP (1) | JP2006519196A (no) |
KR (1) | KR20050113195A (no) |
CN (1) | CN100417641C (no) |
AR (1) | AR043429A1 (no) |
AT (1) | ATE503740T1 (no) |
AU (1) | AU2004215675B2 (no) |
BR (1) | BRPI0407858A (no) |
CA (1) | CA2516626A1 (no) |
CO (1) | CO5690543A2 (no) |
DE (2) | DE10308352A1 (no) |
HR (1) | HRP20050737A2 (no) |
MA (1) | MA27740A1 (no) |
MX (1) | MXPA05009054A (no) |
NO (1) | NO20054380L (no) |
PE (1) | PE20040957A1 (no) |
PL (1) | PL377736A1 (no) |
RU (1) | RU2005130004A (no) |
TW (1) | TW200505831A (no) |
WO (1) | WO2004076402A1 (no) |
ZA (1) | ZA200505762B (no) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
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US7399777B2 (en) * | 2001-08-31 | 2008-07-15 | Sanofi-Aventis Deutschland Gmbh | Diarylcycloalkyl derivatives, processes for their preparation and their use as pharmceuticals |
KR20070050475A (ko) | 2004-08-11 | 2007-05-15 | 교린 세이야꾸 가부시키 가이샤 | 신규 환상 아미노 안식향산 유도체 |
KR20070116644A (ko) * | 2005-03-23 | 2007-12-10 | 교린 세이야꾸 가부시키 가이샤 | 신규 환상 아미노페닐알칸산 유도체 |
NZ566877A (en) | 2005-09-29 | 2010-05-28 | Sanofi Aventis | Phenyl-1,2,4-oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals |
WO2012110227A1 (en) | 2011-02-18 | 2012-08-23 | Saudi Basic Industries Corporation | Multinuclear metallocene catalyst complexes for olefin polymerisation and copolymerisation and method of preparing thereof |
US20180044610A1 (en) * | 2015-03-09 | 2018-02-15 | The Lubrizol Corporation | Method Of Lubricating An Internal Combustion Engine |
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2003
- 2003-02-27 DE DE10308352A patent/DE10308352A1/de not_active Withdrawn
-
2004
- 2004-02-19 EP EP04712515A patent/EP1601643B1/de not_active Expired - Lifetime
- 2004-02-19 CA CA002516626A patent/CA2516626A1/en not_active Abandoned
- 2004-02-19 MX MXPA05009054A patent/MXPA05009054A/es active IP Right Grant
- 2004-02-19 CN CNB2004800054773A patent/CN100417641C/zh not_active Expired - Fee Related
- 2004-02-19 RU RU2005130004/04A patent/RU2005130004A/ru not_active Application Discontinuation
- 2004-02-19 WO PCT/EP2004/001583 patent/WO2004076402A1/de active Application Filing
- 2004-02-19 AT AT04712515T patent/ATE503740T1/de active
- 2004-02-19 DE DE502004012351T patent/DE502004012351D1/de not_active Expired - Lifetime
- 2004-02-19 AU AU2004215675A patent/AU2004215675B2/en not_active Ceased
- 2004-02-19 KR KR1020057015772A patent/KR20050113195A/ko not_active Application Discontinuation
- 2004-02-19 JP JP2006501889A patent/JP2006519196A/ja active Pending
- 2004-02-19 BR BRPI0407858-6A patent/BRPI0407858A/pt not_active IP Right Cessation
- 2004-02-19 PL PL377736A patent/PL377736A1/pl not_active Application Discontinuation
- 2004-02-25 TW TW093104701A patent/TW200505831A/zh unknown
- 2004-02-27 AR ARP040100632A patent/AR043429A1/es not_active Application Discontinuation
- 2004-02-27 PE PE2004000202A patent/PE20040957A1/es not_active Application Discontinuation
- 2004-02-27 US US10/789,323 patent/US7220876B2/en active Active
-
2005
- 2005-07-19 ZA ZA200505762A patent/ZA200505762B/en unknown
- 2005-08-26 CO CO05085501A patent/CO5690543A2/es not_active Application Discontinuation
- 2005-08-26 HR HR20050737A patent/HRP20050737A2/xx not_active Application Discontinuation
- 2005-08-26 MA MA28463A patent/MA27740A1/fr unknown
- 2005-09-21 NO NO20054380A patent/NO20054380L/no unknown
Also Published As
Publication number | Publication date |
---|---|
US7220876B2 (en) | 2007-05-22 |
US20040209873A1 (en) | 2004-10-21 |
PE20040957A1 (es) | 2005-01-31 |
CN100417641C (zh) | 2008-09-10 |
AU2004215675B2 (en) | 2010-01-21 |
DE502004012351D1 (de) | 2011-05-12 |
BRPI0407858A (pt) | 2006-03-01 |
TW200505831A (en) | 2005-02-16 |
AU2004215675A1 (en) | 2004-09-10 |
CA2516626A1 (en) | 2004-09-10 |
KR20050113195A (ko) | 2005-12-01 |
MXPA05009054A (es) | 2005-10-19 |
EP1601643A1 (de) | 2005-12-07 |
DE10308352A1 (de) | 2004-09-09 |
PL377736A1 (pl) | 2006-02-20 |
HRP20050737A2 (en) | 2006-07-31 |
CN1753866A (zh) | 2006-03-29 |
JP2006519196A (ja) | 2006-08-24 |
EP1601643B1 (de) | 2011-03-30 |
ZA200505762B (en) | 2006-05-31 |
ATE503740T1 (de) | 2011-04-15 |
AR043429A1 (es) | 2005-07-27 |
MA27740A1 (fr) | 2006-02-01 |
RU2005130004A (ru) | 2006-01-27 |
CO5690543A2 (es) | 2006-10-31 |
WO2004076402A1 (de) | 2004-09-10 |
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