NO20080359L - Krystallinsk base av escitalopram og orodispergerbare tabletter omfattende escitalopram base - Google Patents

Krystallinsk base av escitalopram og orodispergerbare tabletter omfattende escitalopram base

Info

Publication number
NO20080359L
NO20080359L NO20080359A NO20080359A NO20080359L NO 20080359 L NO20080359 L NO 20080359L NO 20080359 A NO20080359 A NO 20080359A NO 20080359 A NO20080359 A NO 20080359A NO 20080359 L NO20080359 L NO 20080359L
Authority
NO
Norway
Prior art keywords
escitalopram
base
salts
crystalline
oxalate
Prior art date
Application number
NO20080359A
Other languages
English (en)
Norwegian (no)
Inventor
Hans Petersen
Ole Nielsen
Michael Harold Rock
Robert Dancer
Helle Eliasen
Ken Lijegren
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37546630&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20080359(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of NO20080359L publication Critical patent/NO20080359L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00Purification; Separation; Stabilisation; Use of additives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
NO20080359A 2005-06-22 2008-01-18 Krystallinsk base av escitalopram og orodispergerbare tabletter omfattende escitalopram base NO20080359L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200500912 2005-06-22
PCT/DK2006/000366 WO2006136169A2 (en) 2005-06-22 2006-06-22 Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base

Publications (1)

Publication Number Publication Date
NO20080359L true NO20080359L (no) 2008-01-18

Family

ID=37546630

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20080359A NO20080359L (no) 2005-06-22 2008-01-18 Krystallinsk base av escitalopram og orodispergerbare tabletter omfattende escitalopram base
NO20101777A NO20101777L (no) 2005-06-22 2010-12-20 Orodispergerbare tabletter

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20101777A NO20101777L (no) 2005-06-22 2010-12-20 Orodispergerbare tabletter

Country Status (39)

Country Link
EP (3) EP2325177A1 (cs)
JP (5) JP4906852B2 (cs)
KR (5) KR20100133023A (cs)
CN (2) CN101189220A (cs)
AR (2) AR055062A1 (cs)
AT (3) ATE497500T1 (cs)
AU (2) AU2006261452B2 (cs)
BG (1) BG66086B1 (cs)
BR (1) BRPI0612295A2 (cs)
CA (2) CA2646780A1 (cs)
CY (1) CY1112392T1 (cs)
CZ (3) CZ299906B6 (cs)
DE (2) DE602006019961D1 (cs)
DK (3) DK1896439T4 (cs)
EA (2) EA201001108A1 (cs)
EE (1) EE00773U1 (cs)
ES (2) ES2319073B1 (cs)
FI (2) FI20077133A (cs)
GB (2) GB2448834B (cs)
HR (1) HRP20110093T4 (cs)
HU (1) HUP0800135A3 (cs)
IL (1) IL187454A0 (cs)
IS (1) IS8705A (cs)
LT (1) LT5550B (cs)
LV (1) LV13677B (cs)
MX (1) MX2007015328A (cs)
MY (2) MY143252A (cs)
NO (2) NO20080359L (cs)
PL (2) PL1896439T5 (cs)
PT (1) PT1896439E (cs)
RS (1) RS51575B2 (cs)
SG (1) SG169358A1 (cs)
SI (1) SI1896439T2 (cs)
SK (1) SK500402007A3 (cs)
TR (2) TR200708792T1 (cs)
TW (2) TWI358407B (cs)
UA (1) UA86536C2 (cs)
WO (1) WO2006136169A2 (cs)
ZA (2) ZA200711066B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
WO2008059514A2 (en) * 2006-07-31 2008-05-22 Cadila Healthcare Limited Process for preparing escitalopram
EP2134325A2 (en) * 2007-03-01 2009-12-23 Aurobindo Pharma Limited Stable solid dosage forms of an antidepressant
SI2595979T1 (sl) 2010-07-23 2016-09-30 H. Lundbeck A/S Proces za čiščenje farmacevtsko sprejemljivih soli Escitaloprama
CN103360353A (zh) * 2013-08-07 2013-10-23 中国药科大学 草酸艾司西酞普兰杂质的制备方法
JP2018016569A (ja) * 2016-07-26 2018-02-01 株式会社トクヤマ (1s)−1−[3−(ジメチルアミノ)プロピル]−1−(4−フルオロフェニル)−1,3−ジヒドロイソベンゾフラン−5−カルボニトリル蓚酸塩の製造方法
WO2018190294A1 (ja) * 2017-04-10 2018-10-18 東和薬品株式会社 エスシタロプラム医薬組成物
CN110711198B (zh) * 2018-07-12 2022-03-15 山东大学 D-甘露糖在制备抗抑郁药物中的应用
KR102331187B1 (ko) 2019-04-09 2021-11-26 주식회사 라이트팜텍 에스시탈로프람을 함유하는 안정성이 우수한 경구용 액제 조성물 및 그의 제조방법

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
JPH05222041A (ja) * 1992-02-13 1993-08-31 Mitsubishi Gas Chem Co Inc アデニン誘導体の精製法
SG46962A1 (en) * 1994-01-27 1998-03-20 Janssen Pharmaceutica Inc Rapidly dissolving oral dosage form
US5607697A (en) * 1995-06-07 1997-03-04 Cima Labs, Incorporated Taste masking microparticles for oral dosage forms
EP0993524B1 (en) 1997-06-30 2002-11-20 Beloit Technologies, Inc. Method and apparatus for the high speed application of coating to a traveling paper web
JP3526581B2 (ja) 1997-07-08 2004-05-17 ハー・ルンドベック・アクティーゼルスカブ シタロプラムの製造方法
DE69714480T2 (de) 1997-11-11 2003-03-06 Lundbeck & Co As H Verfahren zur Herstellung von Citalopram
FR2785538B1 (fr) * 1998-11-06 2004-04-09 Prographarm Laboratoires Comprime a delitement rapide perfectionne
US20020071864A1 (en) * 1999-03-25 2002-06-13 Yuhan Corporation Rapidly disintegrable tablet for oral administration
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
JP2001226372A (ja) * 1999-12-06 2001-08-21 Sumika Fine Chemicals Co Ltd ロサルタンの結晶性または結晶化された酸付加塩およびロサルタンの精製方法
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
CA2424770A1 (en) * 2000-10-06 2003-04-03 Takeda Chemical Industries, Ltd. Solid pharmaceutical preparation
JP4446463B2 (ja) * 2000-10-16 2010-04-07 第一三共株式会社 口腔内速崩壊性医薬組成物およびその製造方法
US7799342B2 (en) 2000-12-06 2010-09-21 Wyeth Llc Fast dissolving tablet
KR100439329B1 (ko) * 2000-12-22 2004-07-07 하. 룬트벡 아크티에 셀스카브 순수한 시탈로프람의 제조방법
AU3920201A (en) * 2000-12-28 2001-07-09 H. Lundbeck A/S Process for the preparation of pure citalopram
PL367480A1 (en) * 2001-05-01 2005-02-21 H.Lundbeck A/S The use of enantiomeric pure escitalopram
US6872405B2 (en) * 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
GB0113842D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
AR034612A1 (es) * 2001-06-25 2004-03-03 Lundbeck & Co As H Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
AR034759A1 (es) 2001-07-13 2004-03-17 Lundbeck & Co As H Metodo para la preparacion de escitalopram
CN1660074A (zh) * 2001-07-31 2005-08-31 H·隆德贝克有限公司 含有依他普仑的晶体组合物
IS7239A (is) * 2001-12-14 2004-04-29 H. Lundbeck A/S Aðferð til framleiðslu á essítalóprami
US7148364B2 (en) * 2002-01-07 2006-12-12 Sun Pharmaceutical Industries Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile
FR2834889B1 (fr) * 2002-01-18 2004-04-02 Roquette Freres Forme pharmaceutique solide orodispersible
GB0204607D0 (en) * 2002-02-27 2002-04-10 Matrix Lab Ltd Process
EP2228060A1 (en) * 2002-05-03 2010-09-15 Skyepharma Canada Inc. Oral dosage forms comprising fenofibrate
CA2511142A1 (en) 2002-12-23 2004-07-08 H. Lundbeck A/S Escitalopram hydrobromide and a method for the preparation thereof
CN1510024A (zh) * 2002-12-24 2004-07-07 北京德众万全药物技术开发有限公司 可用于制备西酞普兰(s)-对映异构体的新的化合物及其制备方法
DE10305984A1 (de) * 2003-02-13 2004-09-02 Helm Ag Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen
US7749533B2 (en) * 2003-05-07 2010-07-06 Akina, Inc. Highly plastic granules for making fast melting tablets
JP4726628B2 (ja) * 2003-10-15 2011-07-20 富士化学工業株式会社 口腔内速崩壊性錠剤
WO2005049596A1 (en) * 2003-11-20 2005-06-02 Natco Pharma Limited A process for the preparation of high purity escitalopram
HU227491B1 (en) * 2003-11-25 2011-07-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Tablet containing citalopram hydrogen bromide
CA2558198A1 (en) * 2004-03-05 2005-09-15 H. Lundbeck A/S Crystalline composition containing escitalopram oxalate
EP1877394A1 (en) * 2005-04-04 2008-01-16 Jubilant Organosys Limited Process for the preparation of escitalopram or its acid addition salts

Also Published As

Publication number Publication date
EA201001108A1 (ru) 2011-02-28
JP2012072168A (ja) 2012-04-12
FI20080548A (fi) 2008-10-07
JP2008546724A (ja) 2008-12-25
HRP20110093T1 (hr) 2011-03-31
JP4415056B2 (ja) 2010-02-17
LV13677B (en) 2008-05-20
JP2009179635A (ja) 2009-08-13
TR200708792T1 (tr) 2008-05-21
AU2006261452A1 (en) 2006-12-28
PL1896439T3 (pl) 2011-04-29
AU2010200844A1 (en) 2010-04-01
CZ301286B6 (cs) 2009-12-30
EA019239B1 (ru) 2014-02-28
GB0811164D0 (en) 2008-07-23
KR101340815B1 (ko) 2013-12-11
CY1112392T1 (el) 2015-12-09
WO2006136169A2 (en) 2006-12-28
JP5731957B2 (ja) 2015-06-10
LT2008005A (en) 2008-10-27
SG169358A1 (en) 2011-03-30
KR20110084341A (ko) 2011-07-21
EP1896439A2 (en) 2008-03-12
IS8705A (is) 2008-01-14
GB0724557D0 (en) 2008-01-23
GB2442160B (en) 2010-01-20
ES2319073B1 (es) 2010-02-26
ES2356838T5 (es) 2015-01-26
BRPI0612295A2 (pt) 2011-01-04
JP4906852B2 (ja) 2012-03-28
PL1896439T5 (pl) 2016-01-29
GB2448834A (en) 2008-10-29
CZ2007898A3 (cs) 2008-01-23
ATE497500T1 (de) 2011-02-15
JP2009179634A (ja) 2009-08-13
AT11883U1 (de) 2011-06-15
MY143239A (en) 2011-04-15
IL187454A0 (en) 2008-02-09
EP2325177A1 (en) 2011-05-25
FI20077133A (fi) 2007-12-20
CN101189220A (zh) 2008-05-28
CA2646780A1 (en) 2006-12-28
CZ300686B6 (cs) 2009-07-15
TW200740785A (en) 2007-11-01
AR079750A2 (es) 2012-02-15
DE112006001619T5 (de) 2008-06-12
SK500402007A3 (sk) 2008-05-06
ES2319073A1 (es) 2009-05-01
KR20110033310A (ko) 2011-03-30
RS51575B2 (sr) 2018-02-28
GB2448834B (en) 2010-01-20
ZA200901698B (en) 2010-04-28
CZ299906B6 (cs) 2008-12-29
DK1896439T3 (da) 2011-02-28
BG110024A (bg) 2008-05-30
RS51575B (en) 2011-08-31
EA200800102A1 (ru) 2008-04-28
TR201000625T1 (tr) 2010-03-22
JP2009046506A (ja) 2009-03-05
DK1896439T4 (en) 2015-01-12
SI1896439T1 (sl) 2011-03-31
DE602006019961D1 (de) 2011-03-17
BG66086B1 (bg) 2011-03-31
EP1896439B1 (en) 2011-02-02
PT1896439E (pt) 2011-02-15
TWI347942B (en) 2011-09-01
UA86536C2 (ru) 2009-04-27
PL384185A1 (pl) 2008-06-23
CA2612827C (en) 2010-11-30
TWI358407B (en) 2012-02-21
AT10983U1 (de) 2010-02-15
EE00773U1 (et) 2008-10-15
ES2356838T3 (es) 2011-04-13
AR055062A1 (es) 2007-08-01
KR20120064140A (ko) 2012-06-18
KR20100133023A (ko) 2010-12-20
EP2385044A1 (en) 2011-11-09
HUP0800135A3 (en) 2009-01-28
CN101928269A (zh) 2010-12-29
LT5550B (lt) 2009-03-25
HUP0800135A2 (en) 2008-06-30
MY143252A (en) 2011-04-15
HRP20110093T4 (hr) 2015-02-27
NO20101777L (no) 2008-01-18
TW201130808A (en) 2011-09-16
AU2006261452B2 (en) 2010-02-04
DK200800075A (da) 2008-03-15
MX2007015328A (es) 2008-02-15
GB2442160A (en) 2008-03-26
SI1896439T2 (sl) 2014-12-31
ZA200711066B (en) 2009-07-29
EP1896439B2 (en) 2014-10-15
CA2612827A1 (en) 2006-12-28
KR20080018191A (ko) 2008-02-27
WO2006136169A3 (en) 2007-10-18
DK200900284A (da) 2009-02-27

Similar Documents

Publication Publication Date Title
NO20080359L (no) Krystallinsk base av escitalopram og orodispergerbare tabletter omfattende escitalopram base
HUP0100531A2 (hu) Citalopram kristályos bázisa, eljárás előállítására, és azt tartalmazó gyógyszerkészítmények
NO20080827L (no) Faste doseringsformuleringer av narkotiske legemidler som har forbedret bukal adsorpsjon
JP2010525084A5 (cs)
US20080004338A1 (en) Use of enantiomeric pure escitalopram
NO20071667L (no) Farmasoytisk preparat omfattende levetiracetam og fremgangsmate for fremstilling av preparatet
NO20080284L (no) Cannabionoid aktiv farmasoytisk ingrediens for forbedrede doseringsformer
ES2195554T3 (es) Metodo para la preparacion de citalopram.
NO20052239L (no) Fast preparat
NO20045072L (no) Tablett med hoyt medikamentinnhold
NO20083104L (no) Fast preparat
HUP0302897A2 (hu) Kiváló hatású transzdermális terápiás készítmény a Parkinson-kór kezelésére
DE602005007339D1 (de) Nebivolol und dessen pharmazeutisch unbedenkliche salze, herstellungsverfahren und pharmazeutische zusammensetzungen von nebivolol
HUP0300078A2 (en) Method for the preparation of citalopram
RU2008102238A (ru) Таблетка, содержащая труднорастворимый активный ингредиент
NO20045126L (no) N-acyl piperidinderivater for anvendelse som melanokortinreseptorligander i behandling av fodeforstyrrelser
EA201101119A1 (ru) Дозируемая форма, содержащая пантопразол в качестве активного ингредиента
NO20080669L (no) Acetylenpiperaziner som metabotrofiske glutamatreseptorantagonister
WO2007144080A3 (de) Antidepressiva-kombinations-wafer
ES2280602T3 (es) Uso de 2-(5-(4-fluorofenil)-3-piridilmetilaminometil)-cromano y sus sales fisiologicamente aceptables.
TR200301553A1 (tr) İrbesartan etken maddesi içeren yeni oral farmasötik formülasyonlar
HRP20110225T1 (hr) Nova kombinacija lijekova kao antidepresivi
NO20062810L (no) Fast farmasoytisk preparatform
TH98476A (th) เบสที่เป็นผลึกของเอสซิทาโลแปรม และยาเม็ดกระจายตัวในปากซึ่งประกอบรวมด้วยเอสซิทาโลแปรมเบส
CN101472575A (zh) 5-htp组合疗法

Legal Events

Date Code Title Description
CREP Change of representative

Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104