NO20080359L - Krystallinsk base av escitalopram og orodispergerbare tabletter omfattende escitalopram base - Google Patents

Krystallinsk base av escitalopram og orodispergerbare tabletter omfattende escitalopram base

Info

Publication number
NO20080359L
NO20080359L NO20080359A NO20080359A NO20080359L NO 20080359 L NO20080359 L NO 20080359L NO 20080359 A NO20080359 A NO 20080359A NO 20080359 A NO20080359 A NO 20080359A NO 20080359 L NO20080359 L NO 20080359L
Authority
NO
Norway
Prior art keywords
escitalopram
base
salts
crystalline
oxalate
Prior art date
Application number
NO20080359A
Other languages
English (en)
Norwegian (no)
Inventor
Hans Petersen
Ole Nielsen
Michael Harold Rock
Robert Dancer
Helle Eliasen
Ken Lijegren
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37546630&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20080359(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of NO20080359L publication Critical patent/NO20080359L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00Purification; Separation; Stabilisation; Use of additives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20080359A 2005-06-22 2008-01-18 Krystallinsk base av escitalopram og orodispergerbare tabletter omfattende escitalopram base NO20080359L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200500912 2005-06-22
PCT/DK2006/000366 WO2006136169A2 (en) 2005-06-22 2006-06-22 Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base

Publications (1)

Publication Number Publication Date
NO20080359L true NO20080359L (no) 2008-01-18

Family

ID=37546630

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20080359A NO20080359L (no) 2005-06-22 2008-01-18 Krystallinsk base av escitalopram og orodispergerbare tabletter omfattende escitalopram base
NO20101777A NO20101777L (no) 2005-06-22 2010-12-20 Orodispergerbare tabletter

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20101777A NO20101777L (no) 2005-06-22 2010-12-20 Orodispergerbare tabletter

Country Status (39)

Country Link
EP (3) EP2325177A1 (cs)
JP (5) JP4906852B2 (cs)
KR (5) KR20100133023A (cs)
CN (2) CN101189220A (cs)
AR (2) AR055062A1 (cs)
AT (3) AT10983U1 (cs)
AU (2) AU2006261452B2 (cs)
BG (1) BG66086B1 (cs)
BR (1) BRPI0612295A2 (cs)
CA (2) CA2646780A1 (cs)
CY (1) CY1112392T1 (cs)
CZ (3) CZ299906B6 (cs)
DE (2) DE112006001619T5 (cs)
DK (3) DK1896439T4 (cs)
EA (2) EA019239B1 (cs)
EE (1) EE00773U1 (cs)
ES (2) ES2356838T5 (cs)
FI (2) FI20080548A7 (cs)
GB (2) GB2448834B (cs)
HR (1) HRP20110093T4 (cs)
HU (1) HUP0800135A3 (cs)
IL (1) IL187454A0 (cs)
IS (1) IS8705A (cs)
LT (1) LT5550B (cs)
LV (1) LV13677B (cs)
MX (1) MX2007015328A (cs)
MY (2) MY143239A (cs)
NO (2) NO20080359L (cs)
PL (2) PL384185A1 (cs)
PT (1) PT1896439E (cs)
RS (1) RS51575B2 (cs)
SG (1) SG169358A1 (cs)
SI (1) SI1896439T2 (cs)
SK (1) SK500402007A3 (cs)
TR (2) TR200708792T1 (cs)
TW (2) TWI358407B (cs)
UA (1) UA86536C2 (cs)
WO (1) WO2006136169A2 (cs)
ZA (2) ZA200711066B (cs)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
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GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
WO2008059514A2 (en) * 2006-07-31 2008-05-22 Cadila Healthcare Limited Process for preparing escitalopram
EP2134325A2 (en) * 2007-03-01 2009-12-23 Aurobindo Pharma Limited Stable solid dosage forms of an antidepressant
DK2595979T3 (en) 2010-07-23 2016-05-17 Lundbeck & Co As H A process for the purification of pharmaceutically acceptable salts of escitalopram
CN103360353A (zh) * 2013-08-07 2013-10-23 中国药科大学 草酸艾司西酞普兰杂质的制备方法
JP2018016569A (ja) * 2016-07-26 2018-02-01 株式会社トクヤマ (1s)−1−[3−(ジメチルアミノ)プロピル]−1−(4−フルオロフェニル)−1,3−ジヒドロイソベンゾフラン−5−カルボニトリル蓚酸塩の製造方法
WO2018190294A1 (ja) * 2017-04-10 2018-10-18 東和薬品株式会社 エスシタロプラム医薬組成物
CN110711198B (zh) * 2018-07-12 2022-03-15 山东大学 D-甘露糖在制备抗抑郁药物中的应用
KR102331187B1 (ko) 2019-04-09 2021-11-26 주식회사 라이트팜텍 에스시탈로프람을 함유하는 안정성이 우수한 경구용 액제 조성물 및 그의 제조방법
US20240100012A1 (en) * 2021-01-18 2024-03-28 Mark Hasleton Pharmaceutical dosage form

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JPH05222041A (ja) * 1992-02-13 1993-08-31 Mitsubishi Gas Chem Co Inc アデニン誘導体の精製法
ATE185266T1 (de) * 1994-01-27 1999-10-15 Univ Oklahoma Schnell auflösende orale darreichungsform
US5607697A (en) * 1995-06-07 1997-03-04 Cima Labs, Incorporated Taste masking microparticles for oral dosage forms
DE69717317T2 (de) 1997-06-30 2003-10-02 Beloit Technologies, Inc. Verfahren und vorrichtung zum auftragen einer beschichtung auf eine bei hoher geschwindigkeit laufende papierbahn
EP1015416B1 (en) 1997-07-08 2001-09-19 H. Lundbeck A/S Method for the preparation of citalopram
AU738359B2 (en) 1997-11-11 2001-09-13 H. Lundbeck A/S Method for the preparation of citalopram
FR2785538B1 (fr) * 1998-11-06 2004-04-09 Prographarm Laboratoires Comprime a delitement rapide perfectionne
US20020071864A1 (en) * 1999-03-25 2002-06-13 Yuhan Corporation Rapidly disintegrable tablet for oral administration
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
JP2001226372A (ja) * 1999-12-06 2001-08-21 Sumika Fine Chemicals Co Ltd ロサルタンの結晶性または結晶化された酸付加塩およびロサルタンの精製方法
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
EP1329217A4 (en) * 2000-10-06 2007-04-04 Takeda Pharmaceutical Solid preparations
RU2273472C2 (ru) * 2000-10-16 2006-04-10 Дайити Фармасьютикал Ко., Лтд. Лекарственный состав, быстро распадающийся в ротовой полости, и способ его изготовления
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SK286283B6 (sk) * 2000-12-22 2008-06-06 H. Lundbeck A/S Spôsob výroby čisteného citalopramu
DK1181272T3 (da) * 2000-12-28 2002-12-30 Lundbeck & Co As H Fremgangsmåde til fremstilling af rent citalopram
UA82828C2 (en) * 2001-05-01 2008-05-26 Lundbeck & Co As H The use of enantiomeric pure escitalopram for treatment of depression
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AR034612A1 (es) * 2001-06-25 2004-03-03 Lundbeck & Co As H Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
AR034759A1 (es) 2001-07-13 2004-03-17 Lundbeck & Co As H Metodo para la preparacion de escitalopram
DK1522539T3 (da) * 2001-07-31 2007-05-07 Lundbeck & Co As H Krystallinsk komposition indeholdende excitalopram
IS7239A (is) 2001-12-14 2004-04-29 H. Lundbeck A/S Aðferð til framleiðslu á essítalóprami
AU2003222435A1 (en) * 2002-01-07 2003-07-24 Sun Pharmaceutical Industries Limited Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
FR2834889B1 (fr) * 2002-01-18 2004-04-02 Roquette Freres Forme pharmaceutique solide orodispersible
GB0204607D0 (en) * 2002-02-27 2002-04-10 Matrix Lab Ltd Process
CA2484375C (en) * 2002-05-03 2012-04-10 Skyepharma Canada Inc. Oral dosage forms comprising fenofibrate
UA80170C2 (en) 2002-12-23 2007-08-27 Lundbeck & Co As H Escitalopram hydrobromide
CN1510024A (zh) * 2002-12-24 2004-07-07 北京德众万全药物技术开发有限公司 可用于制备西酞普兰(s)-对映异构体的新的化合物及其制备方法
DE10305984A1 (de) * 2003-02-13 2004-09-02 Helm Ag Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen
CA2524806C (en) * 2003-05-07 2011-07-12 Akina, Inc. Highly plastic granules for making fast melting tablets
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HU227491B1 (en) * 2003-11-25 2011-07-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Tablet containing citalopram hydrogen bromide
WO2005084643A1 (en) * 2004-03-05 2005-09-15 H. Lundbeck A/S Crystalline composition containing escitalopram oxalate
WO2006106531A1 (en) * 2005-04-04 2006-10-12 Jubilant Organosys Ltd Process for the preparation of escitalopram or its acid addition salts

Also Published As

Publication number Publication date
CA2612827A1 (en) 2006-12-28
JP2009179635A (ja) 2009-08-13
KR20080018191A (ko) 2008-02-27
JP2009179634A (ja) 2009-08-13
EA019239B1 (ru) 2014-02-28
IL187454A0 (en) 2008-02-09
KR20110084341A (ko) 2011-07-21
GB2448834A (en) 2008-10-29
JP2012072168A (ja) 2012-04-12
GB0811164D0 (en) 2008-07-23
LV13677B (en) 2008-05-20
FI20077133L (fi) 2007-12-20
AR079750A2 (es) 2012-02-15
FI20080548L (fi) 2008-10-07
GB2448834B (en) 2010-01-20
EP1896439A2 (en) 2008-03-12
HUP0800135A2 (en) 2008-06-30
ES2319073A1 (es) 2009-05-01
AR055062A1 (es) 2007-08-01
SI1896439T2 (sl) 2014-12-31
FI20080548A7 (fi) 2008-10-07
LT2008005A (en) 2008-10-27
CZ299906B6 (cs) 2008-12-29
KR101340815B1 (ko) 2013-12-11
CY1112392T1 (el) 2015-12-09
AT11883U1 (de) 2011-06-15
IS8705A (is) 2008-01-14
AU2006261452B2 (en) 2010-02-04
AT10983U1 (de) 2010-02-15
CN101189220A (zh) 2008-05-28
CZ300686B6 (cs) 2009-07-15
EP1896439B2 (en) 2014-10-15
RS51575B (en) 2011-08-31
EP2325177A1 (en) 2011-05-25
WO2006136169A2 (en) 2006-12-28
BG110024A (bg) 2008-05-30
ATE497500T1 (de) 2011-02-15
MY143239A (en) 2011-04-15
JP2008546724A (ja) 2008-12-25
EE00773U1 (et) 2008-10-15
CZ2007898A3 (cs) 2008-01-23
TR200708792T1 (tr) 2008-05-21
CZ301286B6 (cs) 2009-12-30
DK1896439T3 (da) 2011-02-28
DK200800075A (da) 2008-03-15
JP4906852B2 (ja) 2012-03-28
SI1896439T1 (sl) 2011-03-31
EA201001108A1 (ru) 2011-02-28
CA2612827C (en) 2010-11-30
PL384185A1 (pl) 2008-06-23
TWI347942B (en) 2011-09-01
CA2646780A1 (en) 2006-12-28
DK200900284A (da) 2009-02-27
HRP20110093T1 (hr) 2011-03-31
JP5731957B2 (ja) 2015-06-10
GB0724557D0 (en) 2008-01-23
FI20077133A7 (fi) 2007-12-20
JP2009046506A (ja) 2009-03-05
LT5550B (lt) 2009-03-25
ES2356838T5 (es) 2015-01-26
GB2442160A (en) 2008-03-26
JP4415056B2 (ja) 2010-02-17
DE112006001619T5 (de) 2008-06-12
TW200740785A (en) 2007-11-01
EP2385044A1 (en) 2011-11-09
WO2006136169A3 (en) 2007-10-18
ZA200711066B (en) 2009-07-29
ES2319073B1 (es) 2010-02-26
PL1896439T3 (pl) 2011-04-29
TR201000625T1 (tr) 2010-03-22
AU2006261452A1 (en) 2006-12-28
HRP20110093T4 (hr) 2015-02-27
GB2442160B (en) 2010-01-20
KR20110033310A (ko) 2011-03-30
CN101928269A (zh) 2010-12-29
ES2356838T3 (es) 2011-04-13
KR20100133023A (ko) 2010-12-20
MX2007015328A (es) 2008-02-15
NO20101777L (no) 2008-01-18
EA200800102A1 (ru) 2008-04-28
TW201130808A (en) 2011-09-16
MY143252A (en) 2011-04-15
SK500402007A3 (sk) 2008-05-06
KR20120064140A (ko) 2012-06-18
AU2010200844A1 (en) 2010-04-01
DK1896439T4 (en) 2015-01-12
PT1896439E (pt) 2011-02-15
BRPI0612295A2 (pt) 2011-01-04
UA86536C2 (ru) 2009-04-27
ZA200901698B (en) 2010-04-28
PL1896439T5 (pl) 2016-01-29
RS51575B2 (sr) 2018-02-28
EP1896439B1 (en) 2011-02-02
HUP0800135A3 (en) 2009-01-28
TWI358407B (en) 2012-02-21
BG66086B1 (bg) 2011-03-31
SG169358A1 (en) 2011-03-30
DE602006019961D1 (de) 2011-03-17

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