TR200708792T1 - Kristal esitalopram bazı ve esitalopram içeren ağızda dağılan tabletler - Google Patents

Kristal esitalopram bazı ve esitalopram içeren ağızda dağılan tabletler

Info

Publication number
TR200708792T1
TR200708792T1 TR2007/08792T TR200708792T TR200708792T1 TR 200708792 T1 TR200708792 T1 TR 200708792T1 TR 2007/08792 T TR2007/08792 T TR 2007/08792T TR 200708792 T TR200708792 T TR 200708792T TR 200708792 T1 TR200708792 T1 TR 200708792T1
Authority
TR
Turkey
Prior art keywords
escitalopram
base
salts
tablets containing
disintegrating tablets
Prior art date
Application number
TR2007/08792T
Other languages
English (en)
Inventor
Dancer Robert
Petersen Hans
Liljegren Ken
Harold Rock Michael
Eliasen Helle
Nielsen Ole
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37546630&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200708792(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of TR200708792T1 publication Critical patent/TR200708792T1/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00—Purification; Separation; Stabilisation; Use of additives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)

Abstract

Mevcut buluş, iyi bilinen antidepresan ilaç esitalopramın kristal bazı, S-1 -[3-(dimetilamino)propil]-1 -(4-florofenil)-1,3-dihidro-5-izobenzofurankarbonitril, sözü edilen bazın formülasyonları, oksalat gibi, esitalopramın saflaştırılmış tuzlarının hazırlanması için, bir bazın kullanıldığı bir proses, sözü edilen proses yoluyla elde edilen tuzlar ve bu tip tuzları içeren formülasyonlar ve saflaştırılmış esitalopram serbest bazının veya oksalat gibi, esilatopramın tuzlarının hazırlanması için, hidrobromürün kullanıldığı bir proses, sözü edilen proses yoluyla elde edilen tuzlar ve bu tip tuzları içeren formülasyonlar ile ilgilidir.
TR2007/08792T 2005-06-22 2006-06-22 Kristal esitalopram bazı ve esitalopram içeren ağızda dağılan tabletler TR200708792T1 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200500912 2005-06-22

Publications (1)

Publication Number Publication Date
TR200708792T1 true TR200708792T1 (tr) 2008-05-21

Family

ID=37546630

Family Applications (2)

Application Number Title Priority Date Filing Date
TR2007/08792T TR200708792T1 (tr) 2005-06-22 2006-06-22 Kristal esitalopram bazı ve esitalopram içeren ağızda dağılan tabletler
TR2010/00625T TR201000625T1 (tr) 2005-06-22 2006-06-22 Kristal esitalopram bazı ve esatilopram baz içeren ağızda dağılan tabletler.

Family Applications After (1)

Application Number Title Priority Date Filing Date
TR2010/00625T TR201000625T1 (tr) 2005-06-22 2006-06-22 Kristal esitalopram bazı ve esatilopram baz içeren ağızda dağılan tabletler.

Country Status (39)

Country Link
EP (3) EP1896439B2 (tr)
JP (5) JP4906852B2 (tr)
KR (5) KR20110084341A (tr)
CN (2) CN101189220A (tr)
AR (2) AR055062A1 (tr)
AT (3) AT10983U1 (tr)
AU (2) AU2006261452B2 (tr)
BG (1) BG66086B1 (tr)
BR (1) BRPI0612295A2 (tr)
CA (2) CA2612827C (tr)
CY (1) CY1112392T1 (tr)
CZ (3) CZ301286B6 (tr)
DE (2) DE112006001619T5 (tr)
DK (3) DK1896439T4 (tr)
EA (2) EA201001108A1 (tr)
EE (1) EE00773U1 (tr)
ES (2) ES2319073B1 (tr)
FI (2) FI20077133A (tr)
GB (2) GB2448834B (tr)
HR (1) HRP20110093T4 (tr)
HU (1) HUP0800135A3 (tr)
IL (1) IL187454A0 (tr)
IS (1) IS8705A (tr)
LT (1) LT5550B (tr)
LV (1) LV13677B (tr)
MX (1) MX2007015328A (tr)
MY (2) MY143239A (tr)
NO (2) NO20080359L (tr)
PL (2) PL1896439T5 (tr)
PT (1) PT1896439E (tr)
RS (1) RS51575B2 (tr)
SG (1) SG169358A1 (tr)
SI (1) SI1896439T2 (tr)
SK (1) SK500402007A3 (tr)
TR (2) TR200708792T1 (tr)
TW (2) TWI358407B (tr)
UA (1) UA86536C2 (tr)
WO (1) WO2006136169A2 (tr)
ZA (2) ZA200711066B (tr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
WO2008059514A2 (en) * 2006-07-31 2008-05-22 Cadila Healthcare Limited Process for preparing escitalopram
EP2134325A2 (en) * 2007-03-01 2009-12-23 Aurobindo Pharma Limited Stable solid dosage forms of an antidepressant
DK2595979T3 (en) 2010-07-23 2016-05-17 Lundbeck & Co As H A process for the purification of pharmaceutically acceptable salts of escitalopram
CN103360353A (zh) * 2013-08-07 2013-10-23 中国药科大学 草酸艾司西酞普兰杂质的制备方法
JP2018016569A (ja) * 2016-07-26 2018-02-01 株式会社トクヤマ （１ｓ）−１−［３−（ジメチルアミノ）プロピル］−１−（４−フルオロフェニル）−１，３−ジヒドロイソベンゾフラン−５−カルボニトリル蓚酸塩の製造方法
JP6423133B1 (ja) * 2017-04-10 2018-11-14 東和薬品株式会社 エスシタロプラム医薬組成物
CN110711198B (zh) * 2018-07-12 2022-03-15 山东大学 D-甘露糖在制备抗抑郁药物中的应用
KR102331187B1 (ko) 2019-04-09 2021-11-26 주식회사 라이트팜텍 에스시탈로프람을 함유하는 안정성이 우수한 경구용 액제 조성물 및 그의 제조방법

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GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
JPH05222041A (ja) * 1992-02-13 1993-08-31 Mitsubishi Gas Chem Co Inc アデニン誘導体の精製法
JP2902785B2 (ja) * 1994-01-27 1999-06-07 ザ ボード オブ リージェンツ オブ ザ ユニヴァーシティ オブ オクラホマ 迅速溶解経口投与剤
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AU4655597A (en) 1997-06-30 1999-01-19 Beloit Technologies, Inc. Method and apparatus for the high speed application of coating to a traveling paper web
DE1015416T1 (de) 1997-07-08 2000-10-05 Lundbeck A S Kobenhavn Valby H Verfahren zur herstellung von citalopram
JP3813820B2 (ja) 1997-11-11 2006-08-23 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
FR2785538B1 (fr) * 1998-11-06 2004-04-09 Prographarm Laboratoires Comprime a delitement rapide perfectionne
US20020071864A1 (en) * 1999-03-25 2002-06-13 Yuhan Corporation Rapidly disintegrable tablet for oral administration
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
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GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
CA2424770A1 (en) * 2000-10-06 2003-04-03 Takeda Chemical Industries, Ltd. Solid pharmaceutical preparation
CA2426682C (en) * 2000-10-16 2010-02-16 Daiichi Pharmaceutical Co., Ltd. Intraoral rapid-disintegrating medicinal compositions and production process thereof
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CA2360303C (en) * 2000-12-22 2003-08-12 Marco Villa Process for the preparation of pure citalopram
PT1181272E (pt) * 2000-12-28 2003-01-31 Lundbeck & Co As H Processo para a preparacao de citalopram puro
CA2445843A1 (en) * 2001-05-01 2002-11-07 H. Lundbeck A/S The use of enantiomeric pure escitalopram
US6872405B2 (en) * 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
GB0113842D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
AR034612A1 (es) * 2001-06-25 2004-03-03 Lundbeck & Co As H Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
AR034759A1 (es) 2001-07-13 2004-03-17 Lundbeck & Co As H Metodo para la preparacion de escitalopram
IL159326A0 (en) * 2001-07-31 2004-06-01 Lundbeck & Co As H Crystalline composition containing escitalopram
IS7239A (is) * 2001-12-14 2004-04-29 H. Lundbeck A/S Aðferð til framleiðslu á essítalóprami
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Also Published As

Publication number Publication date
HRP20110093T1 (hr) 2011-03-31
DE112006001619T5 (de) 2008-06-12
GB2448834A (en) 2008-10-29
ZA200711066B (en) 2009-07-29
KR20100133023A (ko) 2010-12-20
SI1896439T2 (sl) 2014-12-31
SI1896439T1 (sl) 2011-03-31
EP2325177A1 (en) 2011-05-25
TW200740785A (en) 2007-11-01
AR079750A2 (es) 2012-02-15
FI20080548A (fi) 2008-10-07
EP2385044A1 (en) 2011-11-09
AT10983U1 (de) 2010-02-15
MX2007015328A (es) 2008-02-15
TW201130808A (en) 2011-09-16
GB2442160A (en) 2008-03-26
DE602006019961D1 (de) 2011-03-17
MY143239A (en) 2011-04-15
KR20080018191A (ko) 2008-02-27
CN101928269A (zh) 2010-12-29
PL1896439T5 (pl) 2016-01-29
IS8705A (is) 2008-01-14
TWI358407B (en) 2012-02-21
JP2009046506A (ja) 2009-03-05
JP2009179634A (ja) 2009-08-13
NO20101777L (no) 2008-01-18
AT11883U1 (de) 2011-06-15
BRPI0612295A2 (pt) 2011-01-04
JP2008546724A (ja) 2008-12-25
DK200800075A (da) 2008-03-15
CA2612827C (en) 2010-11-30
CZ2007898A3 (cs) 2008-01-23
PL1896439T3 (pl) 2011-04-29
GB2442160B (en) 2010-01-20
PL384185A1 (pl) 2008-06-23
UA86536C2 (ru) 2009-04-27
EA200800102A1 (ru) 2008-04-28
CZ301286B6 (cs) 2009-12-30
LT2008005A (en) 2008-10-27
EP1896439A2 (en) 2008-03-12
PT1896439E (pt) 2011-02-15
HUP0800135A3 (en) 2009-01-28
SG169358A1 (en) 2011-03-30
JP4906852B2 (ja) 2012-03-28
KR20110084341A (ko) 2011-07-21
WO2006136169A3 (en) 2007-10-18
KR20120064140A (ko) 2012-06-18
AR055062A1 (es) 2007-08-01
DK1896439T3 (da) 2011-02-28
CZ299906B6 (cs) 2008-12-29
DK200900284A (da) 2009-02-27
JP2009179635A (ja) 2009-08-13
HRP20110093T4 (hr) 2015-02-27
SK500402007A3 (sk) 2008-05-06
BG110024A (bg) 2008-05-30
BG66086B1 (bg) 2011-03-31
AU2006261452B2 (en) 2010-02-04
EE00773U1 (et) 2008-10-15
HUP0800135A2 (en) 2008-06-30
EP1896439B2 (en) 2014-10-15
WO2006136169A2 (en) 2006-12-28
IL187454A0 (en) 2008-02-09
ES2356838T5 (es) 2015-01-26
GB0811164D0 (en) 2008-07-23
ATE497500T1 (de) 2011-02-15
RS51575B2 (sr) 2018-02-28
NO20080359L (no) 2008-01-18
ES2356838T3 (es) 2011-04-13
EA201001108A1 (ru) 2011-02-28
CY1112392T1 (el) 2015-12-09
EA019239B1 (ru) 2014-02-28
KR20110033310A (ko) 2011-03-30
AU2006261452A1 (en) 2006-12-28
DK1896439T4 (en) 2015-01-12
JP5731957B2 (ja) 2015-06-10
TWI347942B (en) 2011-09-01
MY143252A (en) 2011-04-15
GB0724557D0 (en) 2008-01-23
JP4415056B2 (ja) 2010-02-17
CZ300686B6 (cs) 2009-07-15
JP2012072168A (ja) 2012-04-12
ZA200901698B (en) 2010-04-28
ES2319073A1 (es) 2009-05-01
EP1896439B1 (en) 2011-02-02
ES2319073B1 (es) 2010-02-26
LT5550B (lt) 2009-03-25
KR101340815B1 (ko) 2013-12-11
AU2010200844A1 (en) 2010-04-01
CA2646780A1 (en) 2006-12-28
RS51575B (en) 2011-08-31
CN101189220A (zh) 2008-05-28
TR201000625T1 (tr) 2010-03-22
LV13677B (en) 2008-05-20
GB2448834B (en) 2010-01-20
FI20077133A (fi) 2007-12-20
CA2612827A1 (en) 2006-12-28

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