ATE550326T1 - Als modulatoren von hdl einsetzbare verbindungen - Google Patents
Als modulatoren von hdl einsetzbare verbindungenInfo
- Publication number
- ATE550326T1 ATE550326T1 AT07866668T AT07866668T ATE550326T1 AT E550326 T1 ATE550326 T1 AT E550326T1 AT 07866668 T AT07866668 T AT 07866668T AT 07866668 T AT07866668 T AT 07866668T AT E550326 T1 ATE550326 T1 AT E550326T1
- Authority
- AT
- Austria
- Prior art keywords
- hdl
- modulators
- compounds
- synthesis
- pharmaceutically acceptable
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 238000003786 synthesis reaction Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1213MU2006 | 2006-07-31 | ||
| PCT/IN2007/000321 WO2008059513A2 (en) | 2006-07-31 | 2007-07-27 | Compounds suitable as modulators of hdl |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE550326T1 true ATE550326T1 (de) | 2012-04-15 |
Family
ID=39402095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07866668T ATE550326T1 (de) | 2006-07-31 | 2007-07-27 | Als modulatoren von hdl einsetzbare verbindungen |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8022217B2 (de) |
| EP (1) | EP2049493B1 (de) |
| AT (1) | ATE550326T1 (de) |
| WO (1) | WO2008059513A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2352398B1 (es) * | 2009-06-25 | 2011-09-29 | Institut Univ. De Ciencia I Tecnologia S.A. | N-fenetilsulfonamidas-n-sustituidas para la identificacion de actividad biologica y farmacologica. |
| EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
| JP6744218B2 (ja) * | 2013-11-15 | 2020-08-19 | ザ ウィスター インスティテュート オブ アナトミー アンド バイオロジー | Ｅｂｎａ１阻害剤およびそれらの使用方法 |
| BR112017024481B1 (pt) | 2015-05-14 | 2020-11-17 | The Wistar Institute Of Anatomy And Biology | composto inibidor de ebna1, composição farmacêutica compreendendo dito composto e usos terapêuticos do mesmo |
| CN112543634A (zh) | 2018-05-17 | 2021-03-23 | 威斯达研究所 | Ebna1抑制剂晶体形式及其制备和使用方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH12617A (en) * | 1973-04-13 | 1979-07-05 | Thomae Gmbh Dr K | Aminobenzyl-amides and salts thereof |
| US5728835A (en) * | 1993-12-27 | 1998-03-17 | Toa Eiyo, Ltd. | Substituted cyclic amine compound, production process thereof and pharmaceutical composition for circulatory organ use containing the same |
| US5576335A (en) * | 1994-02-01 | 1996-11-19 | Nisshin Flour Milling Co., Ltd. | Urea derivatives and their use as ACAT inhibitors |
| CZ289721B6 (cs) * | 1995-05-19 | 2002-03-13 | Syngenta Participations Ag | Způsob katalytické hydrogenace aromatických nitrosloučenin |
| EP0881220A4 (de) * | 1996-02-15 | 1999-04-21 | Mitsubishi Chem Corp | Diarylsultam-derivate |
| GB9824579D0 (en) * | 1998-11-10 | 1999-01-06 | Novartis Ag | Organic compounds |
| IL149462A0 (en) * | 2001-05-09 | 2002-11-10 | Warner Lambert Co | Method of treating or inhibiting neutrophil chemotaxis by administering a mek inhibitor |
| ES2277142T3 (es) | 2002-08-30 | 2007-07-01 | Japan Tobacco Inc. | Compuesto de dibencilamina y su uso medicinal. |
| AR042067A1 (es) * | 2002-11-27 | 2005-06-08 | Bayer Pharmaceuticals Corp | Derivados de anilinopirazol utiles en el tratamiento de la diabetes |
| FR2850654A1 (fr) * | 2003-02-03 | 2004-08-06 | Servier Lab | Nouveaux derives d'azepines tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US6987174B2 (en) * | 2003-04-01 | 2006-01-17 | Fuji Photo Film Co., Ltd. | Azo compound, colorant-containing curable composition, color filter and color filter production method |
| WO2005033082A2 (en) * | 2003-09-30 | 2005-04-14 | Pfizer Products Inc. | Cetp inhibitors and metabolites thereof |
| CN1993323B (zh) | 2004-08-05 | 2011-04-20 | 霍夫曼-拉罗奇有限公司 | 吲哚，吲唑或二氢吲哚衍生物 |
| US7572823B2 (en) * | 2006-02-07 | 2009-08-11 | Hoffmann-La Roche Inc. | Heteroaryl carboxamide compounds |
| US7678818B2 (en) * | 2006-02-07 | 2010-03-16 | Hoffmann-La Roche Inc. | Anthranilamide and 2-amino-heteroarene-carboxamide compounds |
| ES2359744T3 (es) | 2006-02-07 | 2011-05-26 | F. Hoffmann-La Roche Ag | Derivados de la benzamida y del heteroareno como inhibidores de la cetp. |
-
2007
- 2007-07-27 EP EP07866668A patent/EP2049493B1/de active Active
- 2007-07-27 WO PCT/IN2007/000321 patent/WO2008059513A2/en not_active Ceased
- 2007-07-27 US US12/374,089 patent/US8022217B2/en not_active Expired - Fee Related
- 2007-07-27 AT AT07866668T patent/ATE550326T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| US20090171091A1 (en) | 2009-07-02 |
| WO2008059513A3 (en) | 2008-08-28 |
| WO2008059513A2 (en) | 2008-05-22 |
| EP2049493B1 (de) | 2012-03-21 |
| US8022217B2 (en) | 2011-09-20 |
| EP2049493A2 (de) | 2009-04-22 |
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