TR200200310T2 - Interlökin-5 inhibe eden 6-azaurasil türevleri. - Google Patents
Interlökin-5 inhibe eden 6-azaurasil türevleri.Info
- Publication number
- TR200200310T2 TR200200310T2 TR2002/00310T TR200200310T TR200200310T2 TR 200200310 T2 TR200200310 T2 TR 200200310T2 TR 2002/00310 T TR2002/00310 T TR 2002/00310T TR 200200310 T TR200200310 T TR 200200310T TR 200200310 T2 TR200200310 T2 TR 200200310T2
- Authority
- TR
- Turkey
- Prior art keywords
- derivatives
- inhibit interleukin
- azauracil
- azauracil derivatives
- methods
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0461—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0463—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0468—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Mevcut bulus eozinofile bagimli enflamatuar hastaliklari tedavisinde faydali IL-5 inhibe eden 6-azaurasil türevlerine, bunlarin hazirlanmasina mahsus yöntemlere ve aramaddelere ve ayni zamanda söz konusu türevleri ihtiva eden farmasötik bilesimlere iliskindir. Ayrica bu tür türevlerin bir ilaç olarak kullanimina ve söz konusu türevleri kullanarak bir reseptörü isaretlemeye veya bir organi görüntülemeye mahsus yöntemlere iliskindir.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99870170 | 1999-08-06 | ||
EP99126035 | 1999-12-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200200310T2 true TR200200310T2 (tr) | 2002-08-21 |
Family
ID=26153219
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2002/00310T TR200200310T2 (tr) | 1999-08-06 | 2000-07-31 | Interlökin-5 inhibe eden 6-azaurasil türevleri. |
Country Status (30)
Country | Link |
---|---|
US (1) | US6911444B2 (tr) |
EP (1) | EP1206471B1 (tr) |
JP (1) | JP2003506451A (tr) |
KR (1) | KR100795484B1 (tr) |
CN (1) | CN1188410C (tr) |
AR (1) | AR025046A1 (tr) |
AT (1) | ATE318811T1 (tr) |
AU (1) | AU780047B2 (tr) |
BG (1) | BG106367A (tr) |
BR (1) | BR0013014A (tr) |
CA (1) | CA2380759A1 (tr) |
CO (1) | CO5050264A1 (tr) |
CZ (1) | CZ2002356A3 (tr) |
DE (1) | DE60026312T2 (tr) |
EA (1) | EA004740B1 (tr) |
EE (1) | EE200200057A (tr) |
ES (1) | ES2260031T3 (tr) |
HK (1) | HK1048634B (tr) |
HR (1) | HRP20020096A2 (tr) |
HU (1) | HUP0202692A3 (tr) |
IL (1) | IL147976A0 (tr) |
MX (1) | MXPA02001343A (tr) |
MY (1) | MY133512A (tr) |
NO (1) | NO322386B1 (tr) |
NZ (1) | NZ516506A (tr) |
PL (1) | PL353475A1 (tr) |
SK (1) | SK1642002A3 (tr) |
TR (1) | TR200200310T2 (tr) |
TW (1) | TWI271404B (tr) |
WO (1) | WO2001010866A1 (tr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
WO2003072554A1 (en) * | 2002-02-28 | 2003-09-04 | Takeda Chemical Industries, Ltd. | Azole compounds |
EP1758874A1 (en) * | 2004-05-29 | 2007-03-07 | 7TM Pharma A/S | Substituted thiazoleacetic acids as crth2 ligands |
EP2331541B1 (en) | 2008-09-04 | 2015-04-22 | Boehringer Ingelheim International GmbH | Indolizine inhibitors of leukotriene production |
JP4743340B1 (ja) * | 2009-10-28 | 2011-08-10 | セントラル硝子株式会社 | 保護膜形成用薬液 |
US8420655B2 (en) | 2009-12-04 | 2013-04-16 | Boehringer Ingelheim International Gmbh | Benzimidazole inhibitors of leukotriene production |
EA201300250A1 (ru) | 2010-08-16 | 2013-08-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Оксадиазольные ингибиторы продуцирования лейкотриена |
EP2609092B1 (en) | 2010-08-26 | 2015-04-01 | Boehringer Ingelheim International GmbH | Oxadiazole inhibitors of leukotriene production |
AU2011305667A1 (en) | 2010-09-23 | 2013-03-21 | Boehringer Ingelheim International Gmbh | Oxadiazole inhibitors of leukotriene production |
JP5828188B2 (ja) * | 2010-09-23 | 2015-12-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ロイコトリエン産生のオキサジアゾール阻害剤 |
JP5928958B2 (ja) | 2010-10-29 | 2016-06-01 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ロイコトリエン生成のベンゾイミダゾールインヒビター |
WO2012061169A1 (en) | 2010-11-01 | 2012-05-10 | Boehringer Ingelheim International Gmbh | Benzimidazole inhibitors of leukotriene production |
WO2012082817A1 (en) | 2010-12-16 | 2012-06-21 | Boehringer Ingelheim International Gmbh | Biarylamide inhibitors of leukotriene production |
AR089853A1 (es) | 2012-02-01 | 2014-09-24 | Boehringer Ingelheim Int | Inhibidores de oxadiazol de la produccion de leucotrienos para terapia de combinacion, composicion farmaceutica, uso |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US42416A (en) * | 1864-04-19 | Improvement in harvesters | ||
US10177A (en) * | 1853-11-01 | Improved pen and pencil case | ||
FR2476087A1 (fr) * | 1980-02-18 | 1981-08-21 | Roussel Uclaf | Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkyl-thiomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
CA1244024A (en) | 1984-08-01 | 1988-11-01 | Gustaaf M. Boeckx | .alpha.- ARYL-4-(4,5-DIHYDRO-3,5-DIOXO-1,2,4-TRIAZIN- 2(3H)-YL)BENZENEACETONITRILES |
US4631278A (en) | 1984-08-01 | 1986-12-23 | Janssen Pharmaceutica N.V. | Anti-protozoal α-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-benzeneacetonitrile derivatives, pharmaceutical compositions, and method of use therefor |
GB8602342D0 (en) | 1986-01-30 | 1986-03-05 | Janssen Pharmaceutica Nv | 5 6-dihydro-2-(substituted phenyl)-1 2 4-triazine-3 5(2h 4h)-diones |
TR200000153T2 (tr) * | 1997-07-10 | 2000-07-21 | Janssen Pharmaceutica N.V. | İl-5 inhibite eden 6-azaurasil türevleri. |
CN1261881A (zh) | 1997-07-10 | 2000-08-02 | 詹森药业有限公司 | 作为il-5-抑制剂的6-氮杂尿嘧啶衍生物 |
EP0987265A1 (en) | 1998-09-18 | 2000-03-22 | Janssen Pharmaceutica N.V. | Interleukin-5 inhibiting 6-azauracil derivatives |
-
2000
- 2000-07-31 AT AT00948015T patent/ATE318811T1/de not_active IP Right Cessation
- 2000-07-31 CA CA002380759A patent/CA2380759A1/en not_active Abandoned
- 2000-07-31 CN CNB008113394A patent/CN1188410C/zh not_active Expired - Fee Related
- 2000-07-31 BR BR0013014-1A patent/BR0013014A/pt not_active Application Discontinuation
- 2000-07-31 EE EEP200200057A patent/EE200200057A/xx unknown
- 2000-07-31 JP JP2001515675A patent/JP2003506451A/ja not_active Withdrawn
- 2000-07-31 KR KR1020027000704A patent/KR100795484B1/ko not_active IP Right Cessation
- 2000-07-31 CZ CZ2002356A patent/CZ2002356A3/cs unknown
- 2000-07-31 MX MXPA02001343A patent/MXPA02001343A/es active IP Right Grant
- 2000-07-31 SK SK164-2002A patent/SK1642002A3/sk not_active Application Discontinuation
- 2000-07-31 WO PCT/EP2000/007358 patent/WO2001010866A1/en active IP Right Grant
- 2000-07-31 EA EA200200232A patent/EA004740B1/ru not_active IP Right Cessation
- 2000-07-31 ES ES00948015T patent/ES2260031T3/es not_active Expired - Lifetime
- 2000-07-31 AU AU61609/00A patent/AU780047B2/en not_active Ceased
- 2000-07-31 IL IL14797600A patent/IL147976A0/xx not_active IP Right Cessation
- 2000-07-31 EP EP00948015A patent/EP1206471B1/en not_active Expired - Lifetime
- 2000-07-31 HU HU0202692A patent/HUP0202692A3/hu unknown
- 2000-07-31 TR TR2002/00310T patent/TR200200310T2/tr unknown
- 2000-07-31 DE DE60026312T patent/DE60026312T2/de not_active Expired - Fee Related
- 2000-07-31 NZ NZ516506A patent/NZ516506A/xx unknown
- 2000-07-31 PL PL00353475A patent/PL353475A1/xx unknown
- 2000-08-03 MY MYPI20003534 patent/MY133512A/en unknown
- 2000-08-04 CO CO00058843A patent/CO5050264A1/es unknown
- 2000-08-04 TW TW089115824A patent/TWI271404B/zh not_active IP Right Cessation
- 2000-08-04 AR ARP000104044A patent/AR025046A1/es unknown
-
2002
- 2002-01-30 HR HR20020096A patent/HRP20020096A2/hr not_active Application Discontinuation
- 2002-01-30 BG BG06367A patent/BG106367A/bg unknown
- 2002-02-05 NO NO20020565A patent/NO322386B1/no not_active IP Right Cessation
- 2002-02-14 US US10/075,876 patent/US6911444B2/en not_active Expired - Fee Related
-
2003
- 2003-01-28 HK HK03100718.8A patent/HK1048634B/zh not_active IP Right Cessation
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