NO20075635L - Antigenbindende molekyler som har modifiserte Fc-regioner og endret binding til Fc-reseptorer - Google Patents
Antigenbindende molekyler som har modifiserte Fc-regioner og endret binding til Fc-reseptorerInfo
- Publication number
- NO20075635L NO20075635L NO20075635A NO20075635A NO20075635L NO 20075635 L NO20075635 L NO 20075635L NO 20075635 A NO20075635 A NO 20075635A NO 20075635 A NO20075635 A NO 20075635A NO 20075635 L NO20075635 L NO 20075635L
- Authority
- NO
- Norway
- Prior art keywords
- antigen
- binding
- binding molecules
- receptors
- regions
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 5
- 102000036639 antigens Human genes 0.000 title abstract 5
- 108091007433 antigens Proteins 0.000 title abstract 5
- 102000009109 Fc receptors Human genes 0.000 title abstract 2
- 108010087819 Fc receptors Proteins 0.000 title abstract 2
- 238000012986 modification Methods 0.000 abstract 2
- 230000004048 modification Effects 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000037765 diseases and disorders Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
SAMMENDRAG Foreliggende oppfinnelse angår antigenbindende molekyler, inkludert antistoffer, omfattende en Fc-region som har én eller flere aminosyremodifikasjoner, hvor det antigenbindende molekylet fremviser endret binding til én eller flere Fc-reseptorer som et resultat av modifikasjonen(e). Oppfinnelsen angår videre polynukleotider og vektorer som koder for slike antigenbindende molekyler, vertsceller omfattende de samme, fremgangsmåter for fremstilling av de antigenbindende molekylene ifølge oppfinnelsen, og deres anvendelse ved behandling av forskjellige sykdommer og forstyrrelser, for eksempel kreft.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67877605P | 2005-05-09 | 2005-05-09 | |
PCT/IB2006/002888 WO2007039818A2 (en) | 2005-05-09 | 2006-05-09 | Antigen binding molecules having modified fc regions and altered binding to fc receptors |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20075635L true NO20075635L (no) | 2008-02-05 |
Family
ID=37906540
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20075635A NO20075635L (no) | 2005-05-09 | 2007-11-06 | Antigenbindende molekyler som har modifiserte Fc-regioner og endret binding til Fc-reseptorer |
Country Status (14)
Country | Link |
---|---|
US (1) | US20070111281A1 (no) |
EP (1) | EP1888649A2 (no) |
JP (1) | JP2008539753A (no) |
KR (1) | KR20080032026A (no) |
CN (1) | CN101228189A (no) |
AU (1) | AU2006298519A1 (no) |
BR (1) | BRPI0611445A2 (no) |
CA (1) | CA2605781A1 (no) |
IL (1) | IL187090A0 (no) |
MX (1) | MX2007013924A (no) |
NO (1) | NO20075635L (no) |
RU (1) | RU2007145509A (no) |
WO (1) | WO2007039818A2 (no) |
ZA (1) | ZA200709630B (no) |
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-
2006
- 2006-05-09 CA CA002605781A patent/CA2605781A1/en not_active Abandoned
- 2006-05-09 EP EP06831545A patent/EP1888649A2/en not_active Withdrawn
- 2006-05-09 RU RU2007145509/13A patent/RU2007145509A/ru not_active Application Discontinuation
- 2006-05-09 MX MX2007013924A patent/MX2007013924A/es not_active Application Discontinuation
- 2006-05-09 CN CNA200680022837XA patent/CN101228189A/zh active Pending
- 2006-05-09 WO PCT/IB2006/002888 patent/WO2007039818A2/en active Application Filing
- 2006-05-09 US US11/430,283 patent/US20070111281A1/en not_active Abandoned
- 2006-05-09 JP JP2008510675A patent/JP2008539753A/ja active Pending
- 2006-05-09 BR BRPI0611445-8A patent/BRPI0611445A2/pt not_active IP Right Cessation
- 2006-05-09 KR KR1020077028318A patent/KR20080032026A/ko not_active Application Discontinuation
- 2006-05-09 AU AU2006298519A patent/AU2006298519A1/en not_active Abandoned
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2007
- 2007-11-01 IL IL187090A patent/IL187090A0/en unknown
- 2007-11-06 NO NO20075635A patent/NO20075635L/no not_active Application Discontinuation
- 2007-11-08 ZA ZA200709630A patent/ZA200709630B/xx unknown
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WO2007039818A8 (en) | 2007-11-22 |
RU2007145509A (ru) | 2009-06-20 |
WO2007039818A2 (en) | 2007-04-12 |
IL187090A0 (en) | 2008-02-09 |
BRPI0611445A2 (pt) | 2010-09-08 |
JP2008539753A (ja) | 2008-11-20 |
CA2605781A1 (en) | 2007-04-12 |
CN101228189A (zh) | 2008-07-23 |
ZA200709630B (en) | 2008-11-26 |
EP1888649A2 (en) | 2008-02-20 |
AU2006298519A1 (en) | 2007-04-12 |
MX2007013924A (es) | 2008-01-28 |
US20070111281A1 (en) | 2007-05-17 |
WO2007039818A3 (en) | 2007-08-30 |
KR20080032026A (ko) | 2008-04-14 |
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