NO20075603L - Nye 5-substituerte 7-amino[1,3]tiazol[4,5-d]pyrimidinderivater - Google Patents

Nye 5-substituerte 7-amino[1,3]tiazol[4,5-d]pyrimidinderivater

Info

Publication number
NO20075603L
NO20075603L NO20075603A NO20075603A NO20075603L NO 20075603 L NO20075603 L NO 20075603L NO 20075603 A NO20075603 A NO 20075603A NO 20075603 A NO20075603 A NO 20075603A NO 20075603 L NO20075603 L NO 20075603L
Authority
NO
Norway
Prior art keywords
thiazole
amino
substituted
disease
pyrimidine derivatives
Prior art date
Application number
NO20075603A
Other languages
English (en)
Norwegian (no)
Inventor
Gunnar Nordvall
Tobias Rein
Colin Ray
Daniel Sohn
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20075603L publication Critical patent/NO20075603L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO20075603A 2005-04-06 2007-11-05 Nye 5-substituerte 7-amino[1,3]tiazol[4,5-d]pyrimidinderivater NO20075603L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0500767 2005-04-06
PCT/SE2006/000399 WO2006107258A1 (en) 2005-04-06 2006-04-03 Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives

Publications (1)

Publication Number Publication Date
NO20075603L true NO20075603L (no) 2008-01-04

Family

ID=37073739

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20075603A NO20075603L (no) 2005-04-06 2007-11-05 Nye 5-substituerte 7-amino[1,3]tiazol[4,5-d]pyrimidinderivater

Country Status (30)

Country Link
US (2) US7947693B2 (cg-RX-API-DMAC7.html)
EP (1) EP1869056B1 (cg-RX-API-DMAC7.html)
JP (1) JP5165553B2 (cg-RX-API-DMAC7.html)
KR (1) KR101335055B1 (cg-RX-API-DMAC7.html)
CN (1) CN101193897B (cg-RX-API-DMAC7.html)
AR (1) AR055890A1 (cg-RX-API-DMAC7.html)
AT (1) ATE487727T1 (cg-RX-API-DMAC7.html)
AU (1) AU2006231836B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0609738A2 (cg-RX-API-DMAC7.html)
CA (1) CA2604017C (cg-RX-API-DMAC7.html)
CY (1) CY1111316T1 (cg-RX-API-DMAC7.html)
DE (1) DE602006018124D1 (cg-RX-API-DMAC7.html)
DK (1) DK1869056T3 (cg-RX-API-DMAC7.html)
ES (1) ES2354450T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20110047T1 (cg-RX-API-DMAC7.html)
IL (1) IL185912A0 (cg-RX-API-DMAC7.html)
MX (1) MX2007012060A (cg-RX-API-DMAC7.html)
NO (1) NO20075603L (cg-RX-API-DMAC7.html)
NZ (1) NZ561460A (cg-RX-API-DMAC7.html)
PL (1) PL1869056T3 (cg-RX-API-DMAC7.html)
PT (1) PT1869056E (cg-RX-API-DMAC7.html)
RS (1) RS51581B (cg-RX-API-DMAC7.html)
RU (1) RU2419623C2 (cg-RX-API-DMAC7.html)
SA (1) SA06270072B1 (cg-RX-API-DMAC7.html)
SI (1) SI1869056T1 (cg-RX-API-DMAC7.html)
TW (1) TW200714605A (cg-RX-API-DMAC7.html)
UA (1) UA90707C2 (cg-RX-API-DMAC7.html)
UY (1) UY29454A1 (cg-RX-API-DMAC7.html)
WO (1) WO2006107258A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200708187B (cg-RX-API-DMAC7.html)

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WO2006046739A1 (ja) 2004-10-29 2006-05-04 Eisai R & D Management Co., Ltd. 炎症性疾患治療剤
AR053347A1 (es) 2005-04-06 2007-05-02 Astrazeneca Ab Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos
TW200820973A (en) 2006-09-29 2008-05-16 Astrazeneca Ab Novel compounds 480
EP2069365A4 (en) * 2006-09-29 2011-11-02 Astrazeneca Ab NOVEL [1, 3] THIAZOLO [4,5-D] PYRIMIDIN-2 (3H) -AMINE 5,7-DISUBSTITUTED DERIVATIVES AND THEIR USE IN THERAPY
HRP20160457T1 (hr) 2008-03-07 2016-05-20 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Derivati 1-benzil-3-hidroksimetilindazola i njihova uporaba u liječenju bolesti baziranih na ekspresiji mcp-1 i cx3cr1
CA2714436C (en) 2008-03-07 2017-06-27 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Novel 1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of mcp-1, cx3cr1 and p40
US8835481B2 (en) 2008-03-07 2014-09-16 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. 1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of MCP-1, CX3CR1 and P40
US9040538B2 (en) 2009-05-21 2015-05-26 Universite Laval Pyrimidines as novel therapeutic agents
JO3437B1 (ar) 2009-10-30 2019-10-20 Esai R & D Man Co Ltd أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها
JP6076913B2 (ja) 2010-12-07 2017-02-08 ドレクセル ユニバーシティ 癌からの転移を阻害する方法
TWI543975B (zh) 2011-09-13 2016-08-01 Eisai R&D Man Co Ltd Pyrrolidin-3-yl acetic acid derivatives
US8476301B2 (en) 2011-09-13 2013-07-02 Eisai R&D Management Co., Ltd. Pyrrolidin-3-ylacetic acid derivative
JP5872105B2 (ja) 2013-03-12 2016-03-01 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピロリジン−3−イル酢酸誘導体の塩およびその結晶
EP3049086A4 (en) 2013-09-27 2017-02-22 Nimbus Iris, Inc. Irak inhibitors and uses thereof
US20180222922A1 (en) * 2015-06-08 2018-08-09 The Johns Hopkins University Radiofluorinated 7-amino-5-thio-thiazolo[4,5-d]pyrimidines for imaging fractalkine receptor (cx3cr1)
US11267817B2 (en) 2017-05-02 2022-03-08 Drexel University Substituted pyrrolo[1,2-a]quinoxalin-4(5H)-ones as CX3CR1 antagonists
GB201807898D0 (en) * 2018-05-15 2018-06-27 Kancera Ab New processes and products with increased chiral purity
GB201811169D0 (en) 2018-07-06 2018-08-29 Kancera Ab New compounds
GB202006849D0 (en) 2020-05-08 2020-06-24 Kancera Ab New use
AU2023362450A1 (en) 2022-10-19 2025-05-29 Astrazeneca Ab 2,4,6-trisubstituted 1,3,5-triazines as modulators of cx 3 cr1
WO2025219939A1 (en) 2024-04-17 2025-10-23 Astrazeneca Ab Salts and polymorphs of cx3cr1 modulators
WO2025219950A1 (en) 2024-04-18 2025-10-23 Astrazeneca Ab Small molecule cx3cr1 modulators
WO2025219947A1 (en) 2024-04-18 2025-10-23 Astrazeneca Ab Thio-substituted 1,3,5-triazine cx3cr1 modulators

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Also Published As

Publication number Publication date
KR20080004483A (ko) 2008-01-09
US20110092519A1 (en) 2011-04-21
PL1869056T3 (pl) 2011-04-29
NZ561460A (en) 2010-12-24
RU2419623C2 (ru) 2011-05-27
DE602006018124D1 (de) 2010-12-23
HK1118556A1 (en) 2009-02-13
ATE487727T1 (de) 2010-11-15
EP1869056A1 (en) 2007-12-26
PT1869056E (pt) 2011-01-13
SA06270072B1 (ar) 2009-02-07
IL185912A0 (en) 2008-01-06
ES2354450T3 (es) 2011-03-15
DK1869056T3 (da) 2011-02-07
AU2006231836B2 (en) 2010-07-15
KR101335055B1 (ko) 2013-12-02
CA2604017A1 (en) 2006-10-12
TW200714605A (en) 2007-04-16
AR055890A1 (es) 2007-09-12
JP2008535835A (ja) 2008-09-04
BRPI0609738A2 (pt) 2011-10-18
RS51581B (sr) 2011-08-31
US20080214578A1 (en) 2008-09-04
UA90707C2 (en) 2010-05-25
CN101193897B (zh) 2010-12-01
EP1869056A4 (en) 2010-02-17
CN101193897A (zh) 2008-06-04
US9440992B2 (en) 2016-09-13
JP5165553B2 (ja) 2013-03-21
AU2006231836A1 (en) 2006-10-12
MX2007012060A (es) 2007-12-13
RU2007140551A (ru) 2009-05-20
EP1869056B1 (en) 2010-11-10
CA2604017C (en) 2012-03-06
US7947693B2 (en) 2011-05-24
SI1869056T1 (sl) 2011-02-28
UY29454A1 (es) 2006-11-30
WO2006107258A1 (en) 2006-10-12
CY1111316T1 (el) 2015-08-05
HRP20110047T1 (hr) 2011-03-31
ZA200708187B (en) 2008-11-26

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