NO20070146L - 4-fenylpyrimidin-2-karbonitril-derivater - Google Patents

4-fenylpyrimidin-2-karbonitril-derivater

Info

Publication number
NO20070146L
NO20070146L NO20070146A NO20070146A NO20070146L NO 20070146 L NO20070146 L NO 20070146L NO 20070146 A NO20070146 A NO 20070146A NO 20070146 A NO20070146 A NO 20070146A NO 20070146 L NO20070146 L NO 20070146L
Authority
NO
Norway
Prior art keywords
phenylpyrimidine
derivatives
carbonitrile derivatives
relates
carbonitrile
Prior art date
Application number
NO20070146A
Other languages
English (en)
Norwegian (no)
Inventor
Jiaqiang Cai
Zoran Rankovic
Jennifer Helen Moir
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Nv filed Critical Organon Nv
Publication of NO20070146L publication Critical patent/NO20070146L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20070146A 2004-06-11 2007-01-09 4-fenylpyrimidin-2-karbonitril-derivater NO20070146L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04253491 2004-06-11
EP04106949 2004-12-23
PCT/EP2005/006266 WO2005121106A1 (en) 2004-06-11 2005-06-09 4-phenyl-pyrimidine-2-carbonitrile derivatives

Publications (1)

Publication Number Publication Date
NO20070146L true NO20070146L (no) 2007-02-02

Family

ID=34972893

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070146A NO20070146L (no) 2004-06-11 2007-01-09 4-fenylpyrimidin-2-karbonitril-derivater

Country Status (26)

Country Link
US (1) US7589095B2 (de)
EP (1) EP1758870B1 (de)
JP (1) JP2008501764A (de)
KR (1) KR20070043779A (de)
CN (1) CN1980897A (de)
AR (1) AR053303A1 (de)
AT (1) ATE404542T1 (de)
AU (1) AU2005251923A1 (de)
BR (1) BRPI0511951A (de)
CA (1) CA2567845A1 (de)
DE (1) DE602005008960D1 (de)
DK (1) DK1758870T3 (de)
EC (1) ECSP067074A (de)
ES (1) ES2313380T3 (de)
IL (1) IL179444A0 (de)
MX (1) MXPA06014423A (de)
MY (1) MY140123A (de)
NO (1) NO20070146L (de)
NZ (1) NZ551772A (de)
PE (1) PE20060432A1 (de)
PL (1) PL1758870T3 (de)
PT (1) PT1758870E (de)
RS (1) RS20060662A (de)
RU (1) RU2382773C2 (de)
TW (1) TW200614993A (de)
WO (1) WO2005121106A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008542219A (ja) * 2005-05-25 2008-11-27 インゲニウム ファーマシューティカルズ ジーエムビーエイチ 疼痛処置法
CN101528039A (zh) 2006-05-26 2009-09-09 路易斯维尔大学研究基金会公司 巨噬细胞迁移抑制因子拮抗剂及其应用方法
JP5566880B2 (ja) 2007-04-24 2014-08-06 インゲニウム ファーマシューティカルズ ジーエムビーエイチ プロテインキナーゼの阻害剤としての4,6−二置換アミノピリミジン誘導体
KR100936278B1 (ko) * 2007-12-14 2010-01-13 한국생명공학연구원 단백질 포스파타제의 활성을 억제하는 피리미딘 유도체또는 이의 약학적으로 허용가능한 염을 유효성분으로함유하는 암 예방 및 치료용 조성물
JP5704924B2 (ja) * 2008-02-01 2015-04-22 オーキッド リサーチ ラボラトリーズ リミティド 新規複素環化合物
WO2011038234A2 (en) 2009-09-24 2011-03-31 University Of Louisville Research Foundation, Inc. Novel iodo pyrimidine derivatives useful for the treatment of macrophage migration inhibitory factor (mif)-implicated diseases and conditions
US9155790B2 (en) 2010-05-20 2015-10-13 University of Lousiville Research Foundation, Inc. Methods and compositions for modulating ocular damage
JP6211522B2 (ja) 2011-10-06 2017-10-11 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH ヘテロシクリルピリ(ミ)ジニルピラゾール
CN104284895B (zh) 2012-04-17 2016-08-31 安斯泰来制药株式会社 含氮双环式芳香族杂环化合物
CN104211645B (zh) * 2014-08-12 2016-08-24 武汉珈瑜科技有限公司 嘧啶类衍生物及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO890521L (no) 1988-02-25 1989-08-28 Bayer Ag Substituerte pyrimidiner.
JP2004518723A (ja) * 2001-02-14 2004-06-24 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー ピリミジンマトリックスメタロプロテイナーゼ阻害剤
GB0121033D0 (en) 2001-08-30 2001-10-24 Novartis Ag Organic compounds
AR036375A1 (es) * 2001-08-30 2004-09-01 Novartis Ag Compuestos pirrolo [2,3-d] pirimidina -2- carbonitrilo, un proceso para su preparacion, una composicion farmaceutica y el uso de dichos compuestos para la preparacion de medicamentos
US20030144234A1 (en) 2001-08-30 2003-07-31 Buxton Francis Paul Methods for the treatment of chronic pain and compositions therefor
SE0201976D0 (sv) * 2002-06-24 2002-06-24 Astrazeneca Ab Novel compounds
SE0201980D0 (sv) 2002-06-24 2002-06-24 Astrazeneca Ab Novel compounds
GB0220187D0 (en) * 2002-08-30 2002-10-09 Novartis Ag Organic compounds
US7326715B2 (en) * 2005-09-23 2008-02-05 N.V. Organon 4-Phenyl-6-substituted-pyrimidine-2-carbonitrile derivatives

Also Published As

Publication number Publication date
WO2005121106A1 (en) 2005-12-22
NZ551772A (en) 2009-05-31
RU2382773C2 (ru) 2010-02-27
US7589095B2 (en) 2009-09-15
KR20070043779A (ko) 2007-04-25
RS20060662A (sr) 2008-09-29
DK1758870T3 (da) 2008-10-20
AU2005251923A1 (en) 2005-12-22
US20080090813A1 (en) 2008-04-17
TW200614993A (en) 2006-05-16
PE20060432A1 (es) 2006-06-23
EP1758870A1 (de) 2007-03-07
DE602005008960D1 (de) 2008-09-25
MXPA06014423A (es) 2007-02-19
PL1758870T3 (pl) 2009-01-30
CA2567845A1 (en) 2005-12-22
ECSP067074A (es) 2007-01-26
PT1758870E (pt) 2008-10-15
CN1980897A (zh) 2007-06-13
BRPI0511951A (pt) 2008-01-29
ATE404542T1 (de) 2008-08-15
IL179444A0 (en) 2007-05-15
AR053303A1 (es) 2007-05-02
HK1100002A1 (en) 2007-08-31
JP2008501764A (ja) 2008-01-24
RU2007101161A (ru) 2008-07-20
MY140123A (en) 2009-11-30
EP1758870B1 (de) 2008-08-13
ES2313380T3 (es) 2009-03-01

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application