NO20082498L - Diarylurea for behandling av pulmonar hypertensjon - Google Patents

Diarylurea for behandling av pulmonar hypertensjon

Info

Publication number
NO20082498L
NO20082498L NO20082498A NO20082498A NO20082498L NO 20082498 L NO20082498 L NO 20082498L NO 20082498 A NO20082498 A NO 20082498A NO 20082498 A NO20082498 A NO 20082498A NO 20082498 L NO20082498 L NO 20082498L
Authority
NO
Norway
Prior art keywords
treatment
pulmonary hypertension
diarylurea
compositions
fluorophenoxy
Prior art date
Application number
NO20082498A
Other languages
English (en)
Inventor
Bernd Riedl
Peter Sandner
Hanna Tinel
Joachim Hutter
Martina Klein
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of NO20082498L publication Critical patent/NO20082498L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Den foreliggende oppfinnelse angår farmasøytiske sammensetninger/preparater for behandling, forebygging eller håndtering av pulmonal hypertensjon omfattende 4{4-[3(4-klor-3-trifluormetylfenyl)-ureido]-3-fluorfenoksy}-pyridin-2-karboksylsyre metylamid eventuelt kombinert med minst en annen terapeutisk agens.
NO20082498A 2005-11-10 2008-06-04 Diarylurea for behandling av pulmonar hypertensjon NO20082498L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP05024509 2005-11-10
EP05027450 2005-12-15
EP06012234 2006-06-14
PCT/EP2006/010406 WO2007054216A1 (en) 2005-11-10 2006-10-30 Diaryl urea for treating pulmonary hypertension

Publications (1)

Publication Number Publication Date
NO20082498L true NO20082498L (no) 2008-08-07

Family

ID=37622057

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082498A NO20082498L (no) 2005-11-10 2008-06-04 Diarylurea for behandling av pulmonar hypertensjon

Country Status (18)

Country Link
US (1) US20100035888A1 (no)
EP (1) EP1948170A1 (no)
JP (1) JP5084736B2 (no)
KR (1) KR20080067000A (no)
AR (1) AR057849A1 (no)
AU (1) AU2006312714A1 (no)
BR (1) BRPI0618522A2 (no)
CA (1) CA2628849A1 (no)
CR (1) CR9953A (no)
EC (1) ECSP088430A (no)
GT (1) GT200800058A (no)
IL (1) IL191178A0 (no)
NO (1) NO20082498L (no)
PE (1) PE20070806A1 (no)
SV (1) SV2009002900A (no)
TW (1) TW200733961A (no)
UY (1) UY29903A1 (no)
WO (1) WO2007054216A1 (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE556713T1 (de) * 1999-01-13 2012-05-15 Bayer Healthcare Llc Omega-carboxyarylsubstituierte-diphenyl- harnstoffe als p38-kinasehemmer
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
US7371763B2 (en) * 2001-04-20 2008-05-13 Bayer Pharmaceuticals Corporation Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
US20080108672A1 (en) * 2002-01-11 2008-05-08 Bernd Riedl Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors
AU2003209116A1 (en) 2002-02-11 2003-09-04 Bayer Pharmaceuticals Corporation Aryl ureas with angiogenesis inhibiting activity
EP3581228A1 (en) * 2003-02-21 2019-12-18 ResMed Pty Ltd Nasal assembly for delivering breathable gas to a patient
US7557129B2 (en) * 2003-02-28 2009-07-07 Bayer Healthcare Llc Cyanopyridine derivatives useful in the treatment of cancer and other disorders
JP4860474B2 (ja) * 2003-05-20 2012-01-25 バイエル、ファーマシューテイカルズ、コーポレイション Ｐｄｇｆｒによって仲介される病気のためのジアリール尿素
DK1663978T3 (da) 2003-07-23 2008-04-07 Bayer Pharmaceuticals Corp Fluorsubstitueret omega-carboxyaryl-diphenylurinstof til behandling og forebyggelse af sygdomme og lidelser
UA91520C2 (en) * 2004-09-29 2010-08-10 Баер Шеринг Фарма Акциенгезельшафт Thermodynamically stable form of tosylate
AR062927A1 (es) * 2006-10-11 2008-12-17 Bayer Healthcare Ag 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada
CA2675980C (en) * 2007-01-19 2016-06-21 Bayer Healthcare Llc Use of dast for treatment of cancers with acquired resistance to kit inhibitors
US20110178137A1 (en) * 2008-06-25 2011-07-21 Bayer Schering Pharma Aktiengesellschaft Diaryl urea for treating heart failure
WO2011130728A1 (en) * 2010-04-17 2011-10-20 Bayer Healthcare Llc Synthetic metabolites of fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention diseases and conditions
WO2012041987A1 (en) 2010-10-01 2012-04-05 Bayer Pharma Aktiengesellschaft Substituted n-(2-arylamino)aryl sulfonamide-containing combinations
US20140127295A1 (en) * 2011-03-14 2014-05-08 Cellworks Group, Inc Compositions, process of preparation of said compositions and method of treating inflammatory diseases
EP3082428A4 (en) 2013-12-09 2017-08-02 Respira Therapeutics, Inc. Pde5 inhibitor powder formulations and methods relating thereto

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003209116A1 (en) * 2002-02-11 2003-09-04 Bayer Pharmaceuticals Corporation Aryl ureas with angiogenesis inhibiting activity
US7888341B2 (en) * 2002-04-10 2011-02-15 The United States Of America As Represented By The Department Of Veterans Affairs Combination of glivec (STI571) with a cyclin-dependent kinase inhibitor, especially flavopiridol, in the treatment of cancer
JP4860474B2 (ja) * 2003-05-20 2012-01-25 バイエル、ファーマシューテイカルズ、コーポレイション Ｐｄｇｆｒによって仲介される病気のためのジアリール尿素
DK1663978T3 (da) * 2003-07-23 2008-04-07 Bayer Pharmaceuticals Corp Fluorsubstitueret omega-carboxyaryl-diphenylurinstof til behandling og forebyggelse af sygdomme og lidelser
EP1850852A4 (en) * 2005-02-22 2009-11-18 Cedars Sinai Medical Center USE OF SILDENAFIL, VARDENAFIL AND OTHER 5-PHOSPHODIESTERASE INHIBITORS TO INCREASE THE PERMEABILITY OF THE ABNORMAL BLOOD-BRAIN DISEASE

Also Published As

Publication number Publication date
WO2007054216A1 (en) 2007-05-18
UY29903A1 (es) 2007-06-29
SV2009002900A (es) 2009-04-28
BRPI0618522A2 (pt) 2011-09-06
CA2628849A1 (en) 2007-05-18
EP1948170A1 (en) 2008-07-30
ECSP088430A (es) 2008-07-30
TW200733961A (en) 2007-09-16
AU2006312714A1 (en) 2007-05-18
IL191178A0 (en) 2009-08-03
GT200800058A (es) 2010-02-23
US20100035888A1 (en) 2010-02-11
CR9953A (es) 2008-10-08
JP5084736B2 (ja) 2012-11-28
PE20070806A1 (es) 2007-09-29
KR20080067000A (ko) 2008-07-17
JP2009514910A (ja) 2009-04-09
AR057849A1 (es) 2007-12-19

Similar Documents

Publication Publication Date Title
NO20082498L (no) Diarylurea for behandling av pulmonar hypertensjon
EA200870216A1 (ru) Амидо соединения и их применение в качестве лекарственных средств
LTC1793824I2 (lt) Naujos farmacinės kompozicijos, apimančios 4-(4-(3-(4-chlor-3-trifluormetilfenil)ureido)-3-fluorfenoksi)piridin-2-karboksirūgštį, hiperproliferacinių sutrikimų gydymui
HRP20050663A2 (en) Malonamide derivatives as gamma-secretase inhibitors
EA200702198A1 (ru) Фармацевтические составы
NO20083836L (no) N-hydroksyakrylamidforbindelser
EA200870019A1 (ru) Лактамовые соединения и способы их применения
WO2008068615A8 (en) Crystalline forms of ( 3 s ) -3- [n- (n' - (2-tert-butylphenyl) oxamyl) alaninyl] amino-5- (2 ', 3 ', 5 ', 6 ' -tetrafluoro phenoxy) -4-0x0penta noic acid
EA200800100A1 (ru) Соединения азаиндазола и способы применения
NO20070994L (no) N-hydroksamid derivater og anvendelse derav
NO20082124L (no) Bifenyloksyeddiksyrederivater for behandling av respiratorisk sykdom
NO20070445L (no) Pyrimidinderivater.
DK1789398T3 (da) 2-amino-quinazolin derivater anvendelige som inhibitorer af B-sekretase (BACE)
NO20054876L (no) Substituerte 4-fenyltetrahydroisokinoliner, fremgangsmate for fremstilling derav, deres anvendelse som medikament og medikament inneholdende slike forbindelser
WO2003062191A8 (en) N-(4-substituted phenyl)-anthranilic acid hydroxamate esters
SE0403006D0 (sv) New compounds
EA202090029A1 (ru) Твердая композиция карипразина для орального введения
EA200971087A1 (ru) Фармацевтические композиции и способ лечения острой мании
NO20070146L (no) 4-fenylpyrimidin-2-karbonitril-derivater
NO20076405L (no) Anvendelse av 24-nor-UDCA
NO20065835L (no) Medikamenter som inneholder N-sulfamoyl-N'-arylpiperaziner for profylakse eller behandling av overvekt og beslektede tilstander
DE602006008186D1 (de) Neues imprägnierverfahren einer textiloberfläche
ATE524463T1 (de) 4-chromenonyl-1,4-dihydropyridincarbonitrile und ihre verwendung
JP2012097036A5 (no)
JP2012097034A5 (no)

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application