NO20065907L - Nye tetrahydropyridotiofener - Google Patents

Nye tetrahydropyridotiofener

Info

Publication number
NO20065907L
NO20065907L NO20065907A NO20065907A NO20065907L NO 20065907 L NO20065907 L NO 20065907L NO 20065907 A NO20065907 A NO 20065907A NO 20065907 A NO20065907 A NO 20065907A NO 20065907 L NO20065907 L NO 20065907L
Authority
NO
Norway
Prior art keywords
tetrahydropyridothiophenes
new
compounds
proliferative
description
Prior art date
Application number
NO20065907A
Other languages
English (en)
Norwegian (no)
Inventor
Thomas Beckers
Mathias Schmidt
Klaus Pekari
Thomas Bar
Bjorn Bartels
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of NO20065907L publication Critical patent/NO20065907L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO20065907A 2004-05-28 2006-12-19 Nye tetrahydropyridotiofener NO20065907L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04102413 2004-05-28
EP04104193 2004-09-01
PCT/EP2005/052384 WO2005118071A2 (en) 2004-05-28 2005-05-25 Tetrahydropyridothiophenes

Publications (1)

Publication Number Publication Date
NO20065907L true NO20065907L (no) 2006-12-19

Family

ID=35045196

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20065907A NO20065907L (no) 2004-05-28 2006-12-19 Nye tetrahydropyridotiofener

Country Status (25)

Country Link
US (2) US7723523B2 (pt)
EP (1) EP1753512B1 (pt)
JP (1) JP4881297B2 (pt)
KR (1) KR20070037578A (pt)
CN (1) CN1988934B (pt)
AT (1) ATE400319T1 (pt)
AU (1) AU2005249718B2 (pt)
BR (1) BRPI0511461A (pt)
CA (1) CA2567648A1 (pt)
CY (1) CY1108399T1 (pt)
DE (1) DE602005008050D1 (pt)
DK (1) DK1753512T3 (pt)
EA (1) EA012280B1 (pt)
ES (1) ES2309765T3 (pt)
HK (1) HK1106171A1 (pt)
HR (1) HRP20080499T3 (pt)
IL (1) IL178727A (pt)
MX (1) MXPA06013383A (pt)
NO (1) NO20065907L (pt)
NZ (1) NZ550513A (pt)
PL (1) PL1753512T3 (pt)
PT (1) PT1753512E (pt)
RS (1) RS50613B (pt)
SI (1) SI1753512T1 (pt)
WO (1) WO2005118071A2 (pt)

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* Cited by examiner, † Cited by third party
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US7723523B2 (en) 2004-05-28 2010-05-25 4Sc Ag Tetrahydropyridothiophenes
ATE397000T1 (de) 2004-06-04 2008-06-15 Nycomed Gmbh Tetrahydropyridothiophenen zur verwendung in der behandlung von krebs
AU2005251485A1 (en) 2004-06-11 2005-12-22 4Sc Ag Tetrahydropyridothiophenes for treating hyperproliferative disorders
AU2006212224A1 (en) 2005-02-09 2006-08-17 4Sc Ag Tetrahydropyridothiophenes for the treatment of proliferative diseases such as cancer
EP1896484A2 (en) 2005-05-25 2008-03-12 Nycomed GmbH Tetrahydropyridothiophenes for use in the treatment of cancer
EP1893618A2 (en) 2005-05-25 2008-03-05 Nycomed GmbH Tetrahydropyridothiophenes for use in the treatment of cancer
WO2008020024A1 (en) * 2006-08-16 2008-02-21 4Sc Ag Ntetrahydropyridothiophene derivatives for the treatment of cancer
JP2010500396A (ja) * 2006-08-16 2010-01-07 4エスツェー アクチェンゲゼルシャフト テトラヒドロベンゾチオフェン誘導体
EP2404608B1 (en) * 2009-03-04 2015-04-01 Otsuka Pharmaceutical Co., Ltd. Cholestanol derivative for combined use
TWI492759B (zh) * 2008-03-05 2015-07-21 Otsuka Pharma Co Ltd 膽甾烷醇衍生物之併用用途
TW201005466A (en) * 2008-07-24 2010-02-01 Advanced Analog Technology Inc Low dropout regulator
DK2350093T3 (da) * 2008-10-24 2012-11-12 Gruenenthal Gmbh Substituerede 4,5,6,7-tetrahydrothienopyridiner som KCNQ2/3-modulatorer til behandling af smerte, epilepsi og urininkontinens.
CN104478850A (zh) * 2014-12-08 2015-04-01 上海应用技术学院 一种2-氨基噻吩-3甲酰胺的衍生物的制备方法
WO2019244047A1 (en) 2018-06-19 2019-12-26 Novartis Ag N-substituted tetrahydrothienopyridine derivatives and uses thereof

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DE272078C (pt)
DE1225167B (de) * 1965-04-07 1966-09-22 Huels Chemische Werke Ag Verfahren zur Herstellung aliphatischer, aromatischer oder gemischt aliphatisch-aromatischer Sulfone
JPS5498337A (en) * 1978-01-06 1979-08-03 Dai Ichi Seiyaku Co Ltd Anticarcinogenic and/or antimetastatic agent
DD272078A1 (de) 1986-04-15 1989-09-27 Dresden Arzneimittel Verfahren zur herstellung von 6-substituierten 2-acylamio-4,5,6,7-tetrahydro-thieno[2,3-c]-pyridin-3-carbonsaeure-derivaten
DE4039734A1 (de) 1990-12-13 1992-06-17 Basf Ag Substituierte 2-aminothiophene enthaltende herbizide mittel
GB9310700D0 (en) 1993-05-24 1993-07-07 Zeneca Ltd Novel composition
JP3074640B2 (ja) * 1995-12-22 2000-08-07 インターナショナル・ビジネス・マシーンズ・コーポレ−ション 液晶表示装置の駆動方法
GB9614718D0 (en) * 1996-07-12 1996-09-04 Bayer Ag 3-ureido-pyridofurans and -pyridothiophenes
ATE308546T1 (de) * 1998-03-12 2005-11-15 Novo Nordisk As Modulatoren der protein tyrosin phosphatase (ptpases)
WO1999046267A1 (en) 1998-03-12 1999-09-16 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
WO2000014090A1 (en) 1998-09-02 2000-03-16 Novo Nordisk A/S 4,5,6,7-tetrahydro-thieno[2,3-c]pyridine derivatives
GB0114185D0 (en) 2001-06-12 2001-08-01 Protherics Molecular Design Lt Compounds
WO2002092076A1 (en) 2001-05-16 2002-11-21 Cytovia, Inc. Substituted coumarins and quinolines as caspases activators
US20040171603A1 (en) * 2001-05-18 2004-09-02 Janos Pato Novel therapeutic targets for the treatment of mycobacterial infections and compounds useful therefor
WO2003084947A1 (en) 2002-04-09 2003-10-16 Axxima Pharmaceuticals Ag 4,5,6,7-tretrahydrobenzo[b] thiophene derivatives and methods for medical intervention against mycrobacterial infections
US20030232994A1 (en) * 2001-10-04 2003-12-18 Shao-Po Lu Bicyclic thiophene derivatives and combinatorial libraries thereof
DE60318826T2 (de) 2002-03-27 2009-01-22 Nycomed Gmbh Alkoxypyridinderivate
JP4103425B2 (ja) * 2002-03-28 2008-06-18 セイコーエプソン株式会社 電気光学装置、電子機器及び投射型表示装置
US7012100B1 (en) 2002-06-04 2006-03-14 Avolix Pharmaceuticals, Inc. Cell migration inhibiting compositions and methods and compositions for treating cancer
ATE421519T1 (de) 2002-09-12 2009-02-15 Merck & Co Inc Substituierte bizyklische thiophen-derivate, diese verbindungen enthaltende zusammensetzungen und anwendungsverfahren
CA2498399A1 (en) 2002-09-12 2004-03-25 Merck & Co., Inc. Method of treating diabetes and related conditions
TW200503994A (en) 2003-01-24 2005-02-01 Novartis Ag Organic compounds
IL154306A0 (en) 2003-02-05 2003-09-17 Rimonyx Pharmaceuticals Ltd Pharmaceutical compositions comprising thieno [2,3-c] pyridine derivatives and use thereof
US7138529B2 (en) 2003-04-16 2006-11-21 Hoffmann-La Roche Inc. Substituted 3-cyanothiophene acetamides as glucagon receptor antagonists
AU2004270394A1 (en) 2003-09-10 2005-03-17 Gpc Biotech Ag Heterobicyclic compounds as pharmaceutically active agents
AU2004276014A1 (en) 2003-10-01 2005-04-07 Altana Pharma Ag Imidazopyridine-derivatives as inducible no-synthase inhibitors
US20050085531A1 (en) 2003-10-03 2005-04-21 Hodge Carl N. Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof
GB0324653D0 (en) 2003-10-22 2003-11-26 Syngenta Participations Ag Fungicides
MXPA06007054A (es) 2003-12-19 2007-04-17 Elixir Pharmaceuticals Inc Metodos para tratar una enfermedad.
US7745630B2 (en) * 2003-12-22 2010-06-29 Justin Stephen Bryans Triazolyl piperidine arginine vasopressin receptor modulators
US7723523B2 (en) 2004-05-28 2010-05-25 4Sc Ag Tetrahydropyridothiophenes
ATE397000T1 (de) * 2004-06-04 2008-06-15 Nycomed Gmbh Tetrahydropyridothiophenen zur verwendung in der behandlung von krebs
AU2005251485A1 (en) 2004-06-11 2005-12-22 4Sc Ag Tetrahydropyridothiophenes for treating hyperproliferative disorders
SE0401970D0 (sv) 2004-08-02 2004-08-02 Astrazeneca Ab Novel compounds
AU2006212224A1 (en) 2005-02-09 2006-08-17 4Sc Ag Tetrahydropyridothiophenes for the treatment of proliferative diseases such as cancer
EP1851230A1 (en) 2005-02-11 2007-11-07 Nycomed GmbH Tetrahydropyridothiophenes as antripoliferative agents for the treatment of cancer
EP1896484A2 (en) 2005-05-25 2008-03-12 Nycomed GmbH Tetrahydropyridothiophenes for use in the treatment of cancer
EP1893618A2 (en) 2005-05-25 2008-03-05 Nycomed GmbH Tetrahydropyridothiophenes for use in the treatment of cancer
JP2010500396A (ja) 2006-08-16 2010-01-07 4エスツェー アクチェンゲゼルシャフト テトラヒドロベンゾチオフェン誘導体

Also Published As

Publication number Publication date
MXPA06013383A (es) 2007-01-23
CN1988934A (zh) 2007-06-27
US7803945B2 (en) 2010-09-28
CN1988934B (zh) 2011-01-05
NZ550513A (en) 2009-10-30
EP1753512B1 (en) 2008-07-09
JP2008500993A (ja) 2008-01-17
SI1753512T1 (sl) 2008-12-31
WO2005118071A2 (en) 2005-12-15
CY1108399T1 (el) 2014-02-12
US20070244112A1 (en) 2007-10-18
IL178727A (en) 2010-12-30
CA2567648A1 (en) 2005-12-15
EA200602157A1 (ru) 2007-06-29
ES2309765T3 (es) 2008-12-16
ATE400319T1 (de) 2008-07-15
JP4881297B2 (ja) 2012-02-22
BRPI0511461A (pt) 2007-12-26
WO2005118071A3 (en) 2006-06-01
AU2005249718A1 (en) 2005-12-15
US7723523B2 (en) 2010-05-25
HRP20080499T3 (en) 2008-11-30
AU2005249718B2 (en) 2011-01-27
IL178727A0 (en) 2007-02-11
PL1753512T3 (pl) 2009-03-31
EA012280B1 (ru) 2009-08-28
HK1106171A1 (en) 2008-03-07
DK1753512T3 (da) 2008-11-17
RS50613B (sr) 2010-06-30
PT1753512E (pt) 2008-10-14
KR20070037578A (ko) 2007-04-05
EP1753512A2 (en) 2007-02-21
US20090270378A1 (en) 2009-10-29
DE602005008050D1 (de) 2008-08-21

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Legal Events

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Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104

FC2A Withdrawal, rejection or dismissal of laid open patent application