NO20065528L - Forbindelser som fremmer vevsvekst. - Google Patents

Forbindelser som fremmer vevsvekst.

Info

Publication number
NO20065528L
NO20065528L NO20065528A NO20065528A NO20065528L NO 20065528 L NO20065528 L NO 20065528L NO 20065528 A NO20065528 A NO 20065528A NO 20065528 A NO20065528 A NO 20065528A NO 20065528 L NO20065528 L NO 20065528L
Authority
NO
Norway
Prior art keywords
seq
human
cdna
retl
retl3
Prior art date
Application number
NO20065528A
Other languages
English (en)
Other versions
NO324957B1 (no
Inventor
Michele Sanicola-Nadel
Catherine Hession
Richard L Cate
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO20065528L publication Critical patent/NO20065528L/no
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Publication of NO324957B1 publication Critical patent/NO324957B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
NO20065528A 1996-05-08 2006-11-30 Anvendelse av monoklonalt antistoff for fremstilling av medikament til behandling av Ret-assosierte lidelser. NO324957B1 (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1742796P 1996-05-08 1996-05-08
US1930096P 1996-06-07 1996-06-07
US2185996P 1996-07-16 1996-07-16
US4353397P 1997-04-11 1997-04-11
PCT/US1997/007726 WO1997044356A2 (en) 1996-05-08 1997-05-07 RET LIGAND (RetL) FOR STIMULATING NEURAL AND RENAL GROWTH

Publications (2)

Publication Number Publication Date
NO20065528L true NO20065528L (no) 1999-01-08
NO324957B1 NO324957B1 (no) 2008-01-14

Family

ID=27360789

Family Applications (2)

Application Number Title Priority Date Filing Date
NO19985231A NO323612B1 (no) 1996-05-08 1998-11-09 Ret-ligandb3 (RetL3) for stimulering av neural og renal vekst, nukleinsyrer som koder for polypeptidet, fusjonsprotein samt antistoff som spesifikt binder polypeptidet.
NO20065528A NO324957B1 (no) 1996-05-08 2006-11-30 Anvendelse av monoklonalt antistoff for fremstilling av medikament til behandling av Ret-assosierte lidelser.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO19985231A NO323612B1 (no) 1996-05-08 1998-11-09 Ret-ligandb3 (RetL3) for stimulering av neural og renal vekst, nukleinsyrer som koder for polypeptidet, fusjonsprotein samt antistoff som spesifikt binder polypeptidet.

Country Status (24)

Country Link
EP (2) EP0914339B1 (no)
JP (1) JP2002515743A (no)
KR (2) KR100587556B1 (no)
CN (2) CN1624126A (no)
AT (1) ATE335003T1 (no)
AU (1) AU732392B2 (no)
BG (2) BG109433A (no)
BR (1) BR9710665A (no)
CA (1) CA2253871C (no)
CZ (1) CZ296516B6 (no)
DE (1) DE69736428T2 (no)
DK (1) DK0914339T3 (no)
EA (1) EA002544B1 (no)
EE (1) EE9800377A (no)
ES (1) ES2270465T3 (no)
IL (1) IL126918A (no)
IS (1) IS2361B (no)
NO (2) NO323612B1 (no)
NZ (1) NZ332706A (no)
PT (1) PT914339E (no)
RO (1) RO120343B1 (no)
SK (1) SK286115B6 (no)
TR (2) TR200103297T2 (no)
WO (1) WO1997044356A2 (no)

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US6696259B1 (en) 1995-11-13 2004-02-24 Licentia Ltd. Assays using glial cell line-derived neurotrophic factor receptors
EP0846764A3 (en) * 1996-11-27 1998-09-30 Smithkline Beecham Plc Glial cell line-derived neurotrophic factor alpha receptor family
AU5516498A (en) * 1996-12-06 1998-06-29 Genetics Institute Inc. Secreted proteins and polynucleotides encoding them
US6372453B1 (en) 1997-02-18 2002-04-16 Genetech, Inc. Neurturin receptor
US6025157A (en) 1997-02-18 2000-02-15 Genentech, Inc. Neurturin receptor
US6777196B2 (en) 1997-02-18 2004-08-17 Genentech, Inc. Neurturin receptor
AU730430B2 (en) * 1997-02-18 2001-03-08 Genentech Inc. Neurturin receptor
WO1998046622A1 (en) * 1997-04-17 1998-10-22 Washington University RECEPTORS FOR TGF-β-RELATED NEUROTROPHIC FACTORS
WO1998053069A2 (en) * 1997-05-20 1998-11-26 Human Genome Sciences, Inc. Gdnf receptors
KR20010012826A (ko) * 1997-05-22 2001-02-26 세파론, 인코포레이티드 신경교 세포주-유래 향신경성 인자 수용체
AU7165998A (en) * 1997-05-30 1998-12-30 Amgen, Inc. Neurotrophic factor receptors
US7026138B1 (en) 1998-03-23 2006-04-11 Genentech, Inc. Polynucleotides encoding GFRα3
NZ506748A (en) * 1998-03-23 2002-10-25 Genentech Inc Nucleic acids encoding a GFR alpha 3 polypeptide; host cell and vectors for production of the GRF alpha 3 protein and an assay for detecting GRFalpha 3 production
US6593133B1 (en) 1998-07-06 2003-07-15 Nsgene A/S Neurotrophic factors
US20020055467A1 (en) 1998-07-06 2002-05-09 Johansen Teit E. Novel neurotrophic factors
AU7103900A (en) * 1999-09-01 2001-03-26 Biogen, Inc. Ret ligand 5 (retl5) compositions and uses thereof
UA91178C2 (ru) 2003-01-31 2010-07-12 Байоджен Айдек Ма Інк. Мутантный неубластин
HUE035337T2 (en) 2010-05-20 2018-05-02 Array Biopharma Inc Macrocyclic compounds as TRK kinase inhibitors
US10023855B2 (en) 2011-10-31 2018-07-17 Macrogen, Inc. Fusion protein comprising C-terminal domain of RET protein and use thereof as a diagnosing marker
WO2014017491A1 (ja) * 2012-07-26 2014-01-30 独立行政法人国立がん研究センター Ｃｅｐ５５遺伝子とｒｅｔ遺伝子との融合遺伝子
EP3457138A3 (en) 2013-04-30 2019-06-19 Université de Montréal Novel biomarkers for acute myeloid leukemia
EP3322706B1 (en) 2015-07-16 2020-11-11 Array Biopharma, Inc. Substituted pyrazolo[1,5-a]pyridine compounds as ret kinase inhibitors
TWI704148B (zh) 2016-10-10 2020-09-11 美商亞雷生物製藥股份有限公司 作為ｒｅｔ激酶抑制劑之經取代吡唑并[1,5-a]吡啶化合物
JOP20190077A1 (ar) 2016-10-10 2019-04-09 Array Biopharma Inc مركبات بيرازولو [1، 5-a]بيريدين بها استبدال كمثبطات كيناز ret
WO2018136663A1 (en) 2017-01-18 2018-07-26 Array Biopharma, Inc. Ret inhibitors
JP6888101B2 (ja) 2017-01-18 2021-06-16 アレイ バイオファーマ インコーポレイテッド ＲＥＴキナーゼ阻害剤としての置換ピラゾロ［１，５−ａ］ピラジン化合物
JOP20190213A1 (ar) 2017-03-16 2019-09-16 Array Biopharma Inc مركبات حلقية ضخمة كمثبطات لكيناز ros1
TWI812649B (zh) 2017-10-10 2023-08-21 美商絡速藥業公司 6-(2-羥基-2-甲基丙氧基)-4-(6-(6-((6-甲氧基吡啶-3-基)甲基)-3,6-二氮雜雙環[3.1.1]庚-3-基)吡啶-3-基)吡唑并[1,5-a]吡啶-3-甲腈之調配物
TWI791053B (zh) 2017-10-10 2023-02-01 美商亞雷生物製藥股份有限公司 6-(2-羥基-2-甲基丙氧基)-4-(6-(6-((6-甲氧基吡啶-3-基)甲基)-3,6-二氮雜雙環[3.1.1]庚-3-基)吡啶-3-基)吡唑并[1,5-a]吡啶-3-甲腈之結晶形式及其醫藥組合物
CA3087972C (en) 2018-01-18 2023-01-10 Array Biopharma Inc. Substituted pyrazolyl[4,3-c]pyridinecompounds as ret kinase inhibitors
WO2019143991A1 (en) 2018-01-18 2019-07-25 Array Biopharma Inc. SUBSTITUTED PYRAZOLO[3,4-d]PYRIMIDINE COMPOUNDS AS RET KINASE INHIBITORS
EP3740491A1 (en) 2018-01-18 2020-11-25 Array Biopharma, Inc. Substituted pyrrolo[2,3-d]pyrimidines compounds as ret kinase inhibitors
US11964988B2 (en) 2018-09-10 2024-04-23 Array Biopharma Inc. Fused heterocyclic compounds as RET kinase inhibitors

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US5169637A (en) 1983-03-24 1992-12-08 The Liposome Company, Inc. Stable plurilamellar vesicles
CA1237671A (en) 1983-08-01 1988-06-07 Michael W. Fountain Enhancement of pharmaceutical activity
US4762915A (en) 1985-01-18 1988-08-09 Liposome Technology, Inc. Protein-liposome conjugates
US4797368A (en) 1985-03-15 1989-01-10 The United States Of America As Represented By The Department Of Health And Human Services Adeno-associated virus as eukaryotic expression vector
US4956288A (en) 1988-04-22 1990-09-11 Biogen, Inc. Method for producing cells containing stably integrated foreign DNA at a high copy number, the cells produced by this method, and the use of these cells to produce the polypeptides coded for by the foreign DNA
US5185154A (en) 1989-02-02 1993-02-09 Liposome Technology, Inc. Method for instant preparation of a drug containing large unilamellar vesicles
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
JP3021800B2 (ja) 1990-07-24 2000-03-15 セイコーエプソン株式会社 半導体装置及びその製造方法
US5219990A (en) 1991-01-28 1993-06-15 Biogen, Inc. Papillomavirus e2 trans-activation repressors
FR2693107B1 (fr) 1992-07-01 1994-09-23 Chauvin Laboratoire Moyens pour la prévention de la cataracte secondaire.
AU1404395A (en) 1993-12-13 1995-07-03 Biogen, Inc. Anti-mullerian hormone receptor polypeptides and antibodies thereto
JP2000501924A (ja) * 1995-11-13 2000-02-22 イバネズ，カルロス 神経膠細胞系由来神経栄養因子のレセプター類
WO1997033912A2 (en) * 1996-03-14 1997-09-18 Genentech, Inc. Uses of gdnf and gdnf receptor
US6455277B1 (en) * 1996-04-22 2002-09-24 Amgen Inc. Polynucleotides encoding human glial cell line-derived neurotrophic factor receptor polypeptides

Also Published As

Publication number Publication date
WO1997044356A2 (en) 1997-11-27
BG102973A (en) 1999-08-31
DE69736428T2 (de) 2007-08-30
SK152498A3 (en) 1999-08-06
TR199802252T2 (xx) 1999-02-22
NO985231L (no) 1999-01-08
IS4884A (is) 1998-11-06
CZ361598A3 (cs) 1999-03-17
EA002544B1 (ru) 2002-06-27
CZ296516B6 (cs) 2006-04-12
EP1757617A1 (en) 2007-02-28
EA199800990A1 (ru) 1999-06-24
CN1624126A (zh) 2005-06-08
DE69736428D1 (de) 2006-09-14
ES2270465T3 (es) 2007-04-01
KR100587556B1 (ko) 2006-06-08
SK286115B6 (sk) 2008-03-05
TR200103297T2 (tr) 2002-06-21
BG109433A (en) 2007-08-31
JP2002515743A (ja) 2002-05-28
DK0914339T3 (da) 2006-12-04
CN1232469A (zh) 1999-10-20
EE9800377A (et) 1999-04-15
CN1163509C (zh) 2004-08-25
BR9710665A (pt) 1999-08-17
IL126918A (en) 2007-06-03
RO120343B1 (ro) 2005-12-30
CA2253871A1 (en) 1997-11-27
AU732392B2 (en) 2001-04-26
NO324957B1 (no) 2008-01-14
EP0914339B1 (en) 2006-08-02
ATE335003T1 (de) 2006-08-15
PT914339E (pt) 2006-12-29
IS2361B (is) 2008-05-15
KR20060024843A (ko) 2006-03-17
BG64907B1 (bg) 2006-08-31
NZ332706A (en) 1999-10-28
NO323612B1 (no) 2007-06-18
IL126918A0 (en) 1999-09-22
NO985231D0 (no) 1998-11-09
KR20050056275A (ko) 2005-06-14
WO1997044356A3 (en) 1998-02-19
CA2253871C (en) 2005-04-26
EP0914339A2 (en) 1999-05-12
AU3472997A (en) 1997-12-09

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