IS4884A - Ret bindill til örvunar vaxtar tauga og thvagfæra - Google Patents

Ret bindill til örvunar vaxtar tauga og thvagfæra

Info

Publication number
IS4884A
IS4884A IS4884A IS4884A IS4884A IS 4884 A IS4884 A IS 4884A IS 4884 A IS4884 A IS 4884A IS 4884 A IS4884 A IS 4884A IS 4884 A IS4884 A IS 4884A
Authority
IS
Iceland
Prior art keywords
seq
human
cdna
retl
retl3
Prior art date
Application number
IS4884A
Other languages
English (en)
Other versions
IS2361B (is
Inventor
Sanicola-Nadel Michele
Hession Catherine
L. Cate Richard
Original Assignee
Biogen Idec Ma Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Ma Inc. filed Critical Biogen Idec Ma Inc.
Publication of IS4884A publication Critical patent/IS4884A/is
Publication of IS2361B publication Critical patent/IS2361B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IS4884A 1996-05-08 1998-11-06 Ret bindill til örvunar vaxtar tauga og þvagfæra IS2361B (is)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1742796P 1996-05-08 1996-05-08
US1930096P 1996-06-07 1996-06-07
US2185996P 1996-07-16 1996-07-16
PCT/US1997/007726 WO1997044356A2 (en) 1996-05-08 1997-05-07 RET LIGAND (RetL) FOR STIMULATING NEURAL AND RENAL GROWTH

Publications (2)

Publication Number Publication Date
IS4884A true IS4884A (is) 1998-11-06
IS2361B IS2361B (is) 2008-05-15

Family

ID=27360789

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4884A IS2361B (is) 1996-05-08 1998-11-06 Ret bindill til örvunar vaxtar tauga og þvagfæra

Country Status (24)

Country Link
EP (2) EP0914339B1 (is)
JP (1) JP2002515743A (is)
KR (2) KR20060024843A (is)
CN (2) CN1624126A (is)
AT (1) ATE335003T1 (is)
AU (1) AU732392B2 (is)
BG (2) BG109433A (is)
BR (1) BR9710665A (is)
CA (1) CA2253871C (is)
CZ (1) CZ296516B6 (is)
DE (1) DE69736428T2 (is)
DK (1) DK0914339T3 (is)
EA (1) EA002544B1 (is)
EE (1) EE9800377A (is)
ES (1) ES2270465T3 (is)
IL (1) IL126918A (is)
IS (1) IS2361B (is)
NO (2) NO323612B1 (is)
NZ (1) NZ332706A (is)
PT (1) PT914339E (is)
RO (1) RO120343B1 (is)
SK (1) SK286115B6 (is)
TR (2) TR200103297T2 (is)
WO (1) WO1997044356A2 (is)

Families Citing this family (33)

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US6696259B1 (en) 1995-11-13 2004-02-24 Licentia Ltd. Assays using glial cell line-derived neurotrophic factor receptors
EP0846764A3 (en) * 1996-11-27 1998-09-30 Smithkline Beecham Plc Glial cell line-derived neurotrophic factor alpha receptor family
AU5516498A (en) * 1996-12-06 1998-06-29 Genetics Institute Inc. Secreted proteins and polynucleotides encoding them
US6372453B1 (en) 1997-02-18 2002-04-16 Genetech, Inc. Neurturin receptor
US6777196B2 (en) 1997-02-18 2004-08-17 Genentech, Inc. Neurturin receptor
JP4086324B2 (ja) * 1997-02-18 2008-05-14 ジェネンテク，インコーポレイテッド ニュールツリン受容体
US6025157A (en) * 1997-02-18 2000-02-15 Genentech, Inc. Neurturin receptor
NZ501423A (en) * 1997-04-17 2002-02-01 Univ Washington Receptors for TGF-beta-related neurotrophic factors and use for treating disease
WO1998053069A2 (en) * 1997-05-20 1998-11-26 Human Genome Sciences, Inc. Gdnf receptors
EP1007072A4 (en) * 1997-05-22 2002-06-26 Cephalon Inc RECEPTORS NEUROTROPHER FACTORS FROM A GLIA CELL LINE
EP0983354A2 (en) * 1997-05-30 2000-03-08 Amgen Inc. Neurotrophic factor receptors
IL138593A0 (en) * 1998-03-23 2001-10-31 Genentech Inc GFRα3 AND ITS USES
US7026138B1 (en) 1998-03-23 2006-04-11 Genentech, Inc. Polynucleotides encoding GFRα3
US20020055467A1 (en) 1998-07-06 2002-05-09 Johansen Teit E. Novel neurotrophic factors
US6593133B1 (en) 1998-07-06 2003-07-15 Nsgene A/S Neurotrophic factors
WO2001016169A2 (en) * 1999-09-01 2001-03-08 Biogen, Inc. RET LIGAND 5 (Retl5) FROM HUMAN AND MOUSE
PL383683A1 (pl) 2003-01-31 2008-04-14 Biogen Idec Ma Inc. Koniugaty polimerowe zmutowanej neublastyny
KR102132405B1 (ko) 2010-05-20 2020-07-09 어레이 바이오파마 인크. Trk 키나제 저해제로서의 매크로시클릭 화합물
US10023855B2 (en) * 2011-10-31 2018-07-17 Macrogen, Inc. Fusion protein comprising C-terminal domain of RET protein and use thereof as a diagnosing marker
CN104619841A (zh) * 2012-07-26 2015-05-13 日本国立癌症研究中心 Cep55基因与ret基因的融合基因
US10501802B2 (en) 2013-04-30 2019-12-10 Universite De Montreal Biomarkers for acute myeloid leukemia
LT3322706T (lt) 2015-07-16 2021-03-10 Array Biopharma, Inc. Pakeistieji pirazolo[1,5-a]piridino junginiai, kaip ret kinazės inhibitoriai
TWI704148B (zh) 2016-10-10 2020-09-11 美商亞雷生物製藥股份有限公司 作為ｒｅｔ激酶抑制劑之經取代吡唑并[1,5-a]吡啶化合物
JOP20190077A1 (ar) 2016-10-10 2019-04-09 Array Biopharma Inc مركبات بيرازولو [1، 5-a]بيريدين بها استبدال كمثبطات كيناز ret
WO2018136663A1 (en) 2017-01-18 2018-07-26 Array Biopharma, Inc. Ret inhibitors
CA3049136C (en) 2017-01-18 2022-06-14 Array Biopharma Inc. Substituted pyrazolo[1,5-a]pyrazine compounds as ret kinase inhibitors
JOP20190213A1 (ar) 2017-03-16 2019-09-16 Array Biopharma Inc مركبات حلقية ضخمة كمثبطات لكيناز ros1
TW202410896A (zh) 2017-10-10 2024-03-16 美商絡速藥業公司 6-(2-羥基-2-甲基丙氧基)-4-(6-(6-((6-甲氧基吡啶-3-基)甲基)-3,6-二氮雜雙環[3.1.1]庚-3-基)吡啶-3-基)吡唑并[1,5-a]吡啶-3-甲腈之調配物
TWI791053B (zh) 2017-10-10 2023-02-01 美商亞雷生物製藥股份有限公司 6-(2-羥基-2-甲基丙氧基)-4-(6-(6-((6-甲氧基吡啶-3-基)甲基)-3,6-二氮雜雙環[3.1.1]庚-3-基)吡啶-3-基)吡唑并[1,5-a]吡啶-3-甲腈之結晶形式及其醫藥組合物
JP7060694B2 (ja) 2018-01-18 2022-04-26 アレイ バイオファーマ インコーポレイテッド Ｒｅｔキナーゼ阻害剤としての置換ピロロ［２，３－ｄ］ピリミジン化合物
US11524963B2 (en) 2018-01-18 2022-12-13 Array Biopharma Inc. Substituted pyrazolo[3,4-d]pyrimidines as RET kinase inhibitors
JP6997876B2 (ja) 2018-01-18 2022-02-04 アレイ バイオファーマ インコーポレイテッド Ｒｅｔキナーゼ阻害剤としての置換ピラゾリル［４，３－ｃ］ピリジン化合物
US11964988B2 (en) 2018-09-10 2024-04-23 Array Biopharma Inc. Fused heterocyclic compounds as RET kinase inhibitors

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US5169637A (en) 1983-03-24 1992-12-08 The Liposome Company, Inc. Stable plurilamellar vesicles
CA1237671A (en) 1983-08-01 1988-06-07 Michael W. Fountain Enhancement of pharmaceutical activity
US4762915A (en) 1985-01-18 1988-08-09 Liposome Technology, Inc. Protein-liposome conjugates
US4797368A (en) 1985-03-15 1989-01-10 The United States Of America As Represented By The Department Of Health And Human Services Adeno-associated virus as eukaryotic expression vector
US4956288A (en) 1988-04-22 1990-09-11 Biogen, Inc. Method for producing cells containing stably integrated foreign DNA at a high copy number, the cells produced by this method, and the use of these cells to produce the polypeptides coded for by the foreign DNA
US5185154A (en) 1989-02-02 1993-02-09 Liposome Technology, Inc. Method for instant preparation of a drug containing large unilamellar vesicles
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
JP3021800B2 (ja) 1990-07-24 2000-03-15 セイコーエプソン株式会社 半導体装置及びその製造方法
US5219990A (en) 1991-01-28 1993-06-15 Biogen, Inc. Papillomavirus e2 trans-activation repressors
FR2693107B1 (fr) 1992-07-01 1994-09-23 Chauvin Laboratoire Moyens pour la prévention de la cataracte secondaire.
AU1404395A (en) 1993-12-13 1995-07-03 Biogen, Inc. Anti-mullerian hormone receptor polypeptides and antibodies thereto
AU718979B2 (en) * 1995-11-13 2000-05-04 Urmas Arumae Glial cell line-derived neurotrophic factor receptors
CA2246768C (en) * 1996-03-14 2013-12-31 Genentech, Inc. Uses of gdnf and gdnf receptor
US6455277B1 (en) * 1996-04-22 2002-09-24 Amgen Inc. Polynucleotides encoding human glial cell line-derived neurotrophic factor receptor polypeptides

Also Published As

Publication number Publication date
IL126918A0 (en) 1999-09-22
SK286115B6 (sk) 2008-03-05
EA199800990A1 (ru) 1999-06-24
CZ361598A3 (cs) 1999-03-17
NO20065528L (no) 1999-01-08
EP0914339B1 (en) 2006-08-02
EA002544B1 (ru) 2002-06-27
DE69736428D1 (de) 2006-09-14
CA2253871C (en) 2005-04-26
AU3472997A (en) 1997-12-09
ES2270465T3 (es) 2007-04-01
BG64907B1 (bg) 2006-08-31
CZ296516B6 (cs) 2006-04-12
DE69736428T2 (de) 2007-08-30
NO323612B1 (no) 2007-06-18
PT914339E (pt) 2006-12-29
AU732392B2 (en) 2001-04-26
TR200103297T2 (tr) 2002-06-21
KR20060024843A (ko) 2006-03-17
ATE335003T1 (de) 2006-08-15
SK152498A3 (en) 1999-08-06
DK0914339T3 (da) 2006-12-04
IS2361B (is) 2008-05-15
RO120343B1 (ro) 2005-12-30
NO324957B1 (no) 2008-01-14
BR9710665A (pt) 1999-08-17
TR199802252T2 (xx) 1999-02-22
JP2002515743A (ja) 2002-05-28
CN1624126A (zh) 2005-06-08
WO1997044356A3 (en) 1998-02-19
IL126918A (en) 2007-06-03
EP0914339A2 (en) 1999-05-12
KR100587556B1 (ko) 2006-06-08
NO985231L (no) 1999-01-08
KR20050056275A (ko) 2005-06-14
NO985231D0 (no) 1998-11-09
CN1163509C (zh) 2004-08-25
CN1232469A (zh) 1999-10-20
BG109433A (en) 2007-08-31
EE9800377A (et) 1999-04-15
CA2253871A1 (en) 1997-11-27
WO1997044356A2 (en) 1997-11-27
NZ332706A (en) 1999-10-28
BG102973A (en) 1999-08-31
EP1757617A1 (en) 2007-02-28

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