NO20064934L - Fremgangsmate for fremstilling av et fast, farmasoytisk preparat - Google Patents
Fremgangsmate for fremstilling av et fast, farmasoytisk preparatInfo
- Publication number
- NO20064934L NO20064934L NO20064934A NO20064934A NO20064934L NO 20064934 L NO20064934 L NO 20064934L NO 20064934 A NO20064934 A NO 20064934A NO 20064934 A NO20064934 A NO 20064934A NO 20064934 L NO20064934 L NO 20064934L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- solid pharmaceutical
- pharmaceutical composition
- perindopril
- tablets
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Det er beskrevet en fremgangsmåte for fremstilling av et fast farmasøytisk preparat av perindopril eller et salt derav som unngår et våtgranuleringstrinn og som resulterer i meget stabile farmasøytiske preparater, som tabletter.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE200410019845 DE102004019845A1 (de) | 2004-03-29 | 2004-03-29 | Verfahren zur Herstellung einer festen pharmazeutischen Zusammensetzung |
DE102004059521A DE102004059521A1 (de) | 2004-12-09 | 2004-12-09 | Verfahren zur Herstellung einer festen pharmazeutischen Zusammensetzung |
PCT/EP2005/003277 WO2005094793A1 (en) | 2004-03-29 | 2005-03-29 | Process for preparing a solid pharmaceutical composition |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20064934L true NO20064934L (no) | 2006-10-27 |
Family
ID=34963866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20064934A NO20064934L (no) | 2004-03-29 | 2006-10-27 | Fremgangsmate for fremstilling av et fast, farmasoytisk preparat |
Country Status (14)
Country | Link |
---|---|
US (2) | US20070172524A1 (no) |
EP (1) | EP1729739B1 (no) |
JP (1) | JP4948392B2 (no) |
CY (1) | CY1118180T1 (no) |
DK (1) | DK1729739T3 (no) |
EA (1) | EA011712B1 (no) |
ES (1) | ES2603856T3 (no) |
HR (1) | HRP20161602T1 (no) |
HU (1) | HUE031058T2 (no) |
LT (1) | LT1729739T (no) |
NO (1) | NO20064934L (no) |
PL (1) | PL1729739T3 (no) |
PT (1) | PT1729739T (no) |
WO (1) | WO2005094793A1 (no) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2603856T3 (es) | 2004-03-29 | 2017-03-01 | Les Laboratoires Servier | Procedimiento para preparar una composición farmacéutica sólida |
SI21800A (sl) * | 2004-05-14 | 2005-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nov postopek sinteze perindoprila |
BRPI0615607A2 (pt) * | 2005-08-30 | 2011-05-24 | Lek Pharmaceuticals | composição farmacêutica compreendendo perindopril ou seus sais |
PL1948224T3 (pl) * | 2005-11-17 | 2014-10-31 | Silverstone Pharma Est | Trwały preparat amorficznych soli peryndoprylu, sposób ich wytwarzania, zwłaszcza wytwarzania w skali przemysłowej oraz ich zastosowanie w terapii nadciśnienia |
EP1815857A1 (en) | 2006-02-02 | 2007-08-08 | LEK Pharmaceuticals D.D. | A pharmaceutical composition comprising perindopril |
CA2647705A1 (en) * | 2006-04-19 | 2007-10-25 | Teva Pharmaceutical Industries Ltd. | Stable pharmaceutical compositions of 2-aza-bicyclo[3.3.0]-octane-3-carboxylic acid derivatives |
US20070264330A1 (en) * | 2006-05-15 | 2007-11-15 | Bo Ragnar-Tolf | Pharmaceutical formulations of pimavanserin |
WO2008068577A2 (en) * | 2006-12-01 | 2008-06-12 | Glenmark Pharmaceuticals Limited | Pharmaceutical compositions |
TWI435917B (zh) | 2006-12-27 | 2014-05-01 | Fujifilm Corp | 顏料分散組成物、硬化性組成物、彩色濾光片及其製造方法 |
JP2010516700A (ja) * | 2007-01-18 | 2010-05-20 | エヴォルヴァ エスアー | 置換1,3−ジオキサンおよびそれらの使用 |
SI22543A (sl) | 2007-06-27 | 2008-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nove soli perindoprila |
CN102665764A (zh) * | 2009-12-22 | 2012-09-12 | Fmc有限公司 | 可用作可再压实药物赋形剂的微晶纤维素和碳酸钙组合物 |
PL227900B1 (pl) | 2012-11-15 | 2018-01-31 | Adamed Spolka Z Ograniczona Odpowiedzialnoscia | Kompozycja farmaceutyczna zawierająca inhibitor ACE i bloker kanałów wapniowych, sposób jej wytwarzania i jednostka dawkowania zawierająca tę kompozycję |
WO2016178591A2 (en) | 2015-05-05 | 2016-11-10 | Gene Predit, Sa | Genetic markers and treatment of male obesity |
CN109700774A (zh) * | 2019-03-05 | 2019-05-03 | 上药东英(江苏)药业有限公司 | 一种培哚普利叔丁胺片及其粉末直压工艺 |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
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US4508729A (en) * | 1979-12-07 | 1985-04-02 | Adir | Substituted iminodiacids, their preparation and pharmaceutical compositions containing them |
US4350704A (en) * | 1980-10-06 | 1982-09-21 | Warner-Lambert Company | Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids |
US4425355A (en) * | 1981-02-17 | 1984-01-10 | Warner-Lambert Company | Substituted acyl derivatives of chair form of octahydro-1H-indole-2-carboxylic acids |
US4743450A (en) * | 1987-02-24 | 1988-05-10 | Warner-Lambert Company | Stabilized compositions |
FR2620699B1 (fr) * | 1987-09-17 | 1990-06-01 | Adir | Procede de synthese d'alpha amino acides n alkyles et de leurs esters. application a la synthese de carboxyalkyl dipeptides |
FR2620703B1 (fr) * | 1987-09-17 | 1991-10-04 | Adir | Procede de synthese industrielle de l'acide perhydroindole carboxylique - 2(2s, 3as, 7as). application a la synthese de carboxyalkyl dipeptides |
FR2620709B1 (fr) * | 1987-09-17 | 1990-09-07 | Adir | Procede de synthese industrielle du perindopril et de ses principaux intermediaires de synthese |
US5258525A (en) * | 1991-03-27 | 1993-11-02 | Mcneilab, Inc. | Processes for preparing [2S-(2α,3aβ,7aβ)]octahydro-1H-indole-2-carboxylic acid and esters |
SI9111842A (sl) * | 1991-11-25 | 1998-04-30 | Krka | Stabilna formulacija soli enalaprila, postopek za njeno pripravo in njena uporaba |
FR2771010B1 (fr) * | 1997-11-19 | 2003-08-15 | Adir | Utilisation d'une combinaison d'un inhibiteur de l'enzyme de conversion de l'angiotensine et d'un diuretique pour le traitement des desordres microcirculatoires |
AU5248900A (en) | 1999-06-18 | 2001-01-09 | Takeda Chemical Industries Ltd. | Quickly disintegrating solid preparations |
FR2807037B1 (fr) * | 2000-03-31 | 2002-05-10 | Adir | NOUVEAU PROCEDE DE SYNTHESE DES ESTERS DE LA N-[(s)-1- CARBOXYBUTYL]-(S)-ALANINE ET APPLICATION A LA SYNTHESE DU PERINDOPRIL |
FR2807431B1 (fr) * | 2000-04-06 | 2002-07-19 | Adir | Nouveau procede de synthese du perindopril et de ses sels pharmaceutiquement acceptables |
FR2807430B1 (fr) * | 2000-04-11 | 2002-05-17 | Adir | Nouveau procede de synthese des esters de la n-[(s)-1- carboxybutyl]-(s)-alanine et application a la synthese du perindopril |
FR2811320B1 (fr) * | 2000-07-06 | 2002-08-23 | Adir | Nouvelle forme cristalline alpha du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2811319B1 (fr) * | 2000-07-06 | 2002-08-23 | Adir | Nouvelle forme cristalline beta du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2811318B1 (fr) * | 2000-07-06 | 2002-08-23 | Adir | Nouvelle forme cristalline gamma du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
DE10038364A1 (de) | 2000-08-05 | 2002-05-02 | Hexal Ag | Pharmazeutische, Ramipril enthaltende Brauseformulierung |
US20020119192A1 (en) | 2000-09-22 | 2002-08-29 | Vishwanathan Narayanan Badri | Controlled release formulations for oral administration |
DE10131217A1 (de) * | 2001-06-28 | 2003-01-09 | Solvay Pharm Gmbh | 3-Phenyl-3,7-diazabicyclo 3,3,1 nonan-Verbindungen sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
US6576256B2 (en) | 2001-08-28 | 2003-06-10 | The Brigham And Women's Hospital, Inc. | Treatment of patients at elevated cardiovascular risk with a combination of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin |
CA2357982A1 (en) | 2001-09-28 | 2003-03-28 | Bernard Charles Sherman | Solid compositions comprising ramipril |
PT1443912E (pt) * | 2001-10-12 | 2007-11-28 | Elan Pharma Int Ltd | Composições tendo uma combinação de características de libertação imediata e de libertação controlada |
AU2002346472A1 (en) * | 2001-11-20 | 2003-06-10 | Advanced Inhalation Research, Inc. | Particulate compositions for improving solubility of poorly soluble agents |
DE60312857T2 (de) * | 2002-01-15 | 2008-01-17 | Actavis Group Hf. | Formulierungen von quinapril und verwandte ace-hemmer |
DE60220877T2 (de) * | 2002-01-30 | 2008-04-10 | Les Laboratoires Servier | Verfahren zur Herstellung von hochreinem Perindopril und Zwischenverbindungen nützlich in der Synthese |
WO2003075842A2 (en) * | 2002-03-08 | 2003-09-18 | Teva Pharmeceuticals Usa, Inc. | Stable formulations of angiotensin converting enzyme (ace) inhibitors |
FR2838648B1 (fr) | 2002-04-18 | 2004-05-21 | Servier Lab | Nouveau sel de perindopril et les compositions pharmaceutiques qui le contiennent |
CA2488498A1 (en) * | 2002-06-10 | 2003-12-18 | Elan Pharma International Limited | Nanoparticulate polycosanol formulations and novel polycosanol combinations |
GB0301471D0 (en) | 2003-01-22 | 2003-02-19 | Biochemie Gmbh | Organic compounds |
EP1338591B1 (fr) * | 2003-02-28 | 2005-10-26 | Les Laboratoires Servier | Nouveau procédé de synthèse de l'acide (2S, 3aS, 7aS)-perhydroindole-2-carboxylique et de ses esters, et application à la synthèse du perindopril |
SI1603558T1 (sl) * | 2003-02-28 | 2008-12-31 | Servier S A Lab | Postopek za pripravo perindoprila in njegovih soli |
DK1635792T3 (da) * | 2003-06-26 | 2009-06-15 | Teva Pharma | Stabile farmaceutiske sammensætninger af 2-aza-bicyklo-3.3.0-oktan-3-carboxylsyrederivater |
US6869963B2 (en) * | 2003-07-11 | 2005-03-22 | Sandoz Ag | Stable pharmaceutical compositions containing an ACE inhibitor |
GB2404336A (en) * | 2003-07-30 | 2005-02-02 | Cipla Ltd | Stabilisation of therapeutic agents using a carbonate salt of an amino acid, preferably in the presence of a saccharide, & pharmaceutical compositions thereof |
ES2334900T3 (es) * | 2003-09-01 | 2010-03-17 | Les Laboratoires Servier | Nuevo procedimiento de sintesis de esteres de n-((s)-1-carboxibutil)-(s)-alanina y su aplicacion a la sintesis de perindopril. |
GB2394660A (en) * | 2003-12-17 | 2004-05-05 | Niche Generics Ltd | Stabilisation of pharmaceutical compositions comprising ACE inhibitor by absence of acidic excipients having large specific surface area, eg silicon dioxide |
ES2603856T3 (es) | 2004-03-29 | 2017-03-01 | Les Laboratoires Servier | Procedimiento para preparar una composición farmacéutica sólida |
SI21800A (sl) * | 2004-05-14 | 2005-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nov postopek sinteze perindoprila |
-
2005
- 2005-03-29 ES ES05730288.7T patent/ES2603856T3/es active Active
- 2005-03-29 JP JP2007505484A patent/JP4948392B2/ja not_active Expired - Fee Related
- 2005-03-29 DK DK05730288.7T patent/DK1729739T3/en active
- 2005-03-29 EA EA200601608A patent/EA011712B1/ru not_active IP Right Cessation
- 2005-03-29 EP EP05730288.7A patent/EP1729739B1/en not_active Revoked
- 2005-03-29 LT LTEP05730288.7T patent/LT1729739T/lt unknown
- 2005-03-29 PL PL05730288T patent/PL1729739T3/pl unknown
- 2005-03-29 HU HUE05730288A patent/HUE031058T2/en unknown
- 2005-03-29 WO PCT/EP2005/003277 patent/WO2005094793A1/en active Application Filing
- 2005-03-29 PT PT57302887T patent/PT1729739T/pt unknown
- 2005-03-29 US US10/599,154 patent/US20070172524A1/en not_active Abandoned
-
2006
- 2006-10-27 NO NO20064934A patent/NO20064934L/no not_active Application Discontinuation
-
2009
- 2009-06-03 US US12/477,727 patent/US20100172995A1/en not_active Abandoned
-
2016
- 2016-11-03 CY CY20161101118T patent/CY1118180T1/el unknown
- 2016-11-30 HR HRP20161602TT patent/HRP20161602T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
LT1729739T (lt) | 2016-11-10 |
PT1729739T (pt) | 2016-12-01 |
CY1118180T1 (el) | 2017-06-28 |
JP4948392B2 (ja) | 2012-06-06 |
WO2005094793A1 (en) | 2005-10-13 |
EP1729739A1 (en) | 2006-12-13 |
DK1729739T3 (en) | 2016-10-31 |
EP1729739B1 (en) | 2016-09-28 |
ES2603856T3 (es) | 2017-03-01 |
EA011712B1 (ru) | 2009-04-28 |
HRP20161602T1 (hr) | 2016-12-30 |
PL1729739T3 (pl) | 2017-04-28 |
US20070172524A1 (en) | 2007-07-26 |
US20100172995A1 (en) | 2010-07-08 |
EA200601608A1 (ru) | 2007-02-27 |
HUE031058T2 (en) | 2017-06-28 |
JP2007530623A (ja) | 2007-11-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |