PL1948224T3 - Trwały preparat amorficznych soli peryndoprylu, sposób ich wytwarzania, zwłaszcza wytwarzania w skali przemysłowej oraz ich zastosowanie w terapii nadciśnienia - Google Patents
Trwały preparat amorficznych soli peryndoprylu, sposób ich wytwarzania, zwłaszcza wytwarzania w skali przemysłowej oraz ich zastosowanie w terapii nadciśnieniaInfo
- Publication number
- PL1948224T3 PL1948224T3 PL06813152T PL06813152T PL1948224T3 PL 1948224 T3 PL1948224 T3 PL 1948224T3 PL 06813152 T PL06813152 T PL 06813152T PL 06813152 T PL06813152 T PL 06813152T PL 1948224 T3 PL1948224 T3 PL 1948224T3
- Authority
- PL
- Poland
- Prior art keywords
- preparation
- hypertension
- therapy
- stable formulation
- especially industrial
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SI200500314 | 2005-11-17 | ||
SI200600177A SI22339A (sl) | 2006-07-31 | 2006-07-31 | Stabilna formulacija amorfnega perindopril erbumina, postopek za njeno pripravo v industrijskem merilu in njena uporaba za zdravljenje hipertenzije |
PCT/SI2006/000034 WO2007058634A1 (en) | 2005-11-17 | 2006-11-08 | Stable formulation of amorphous perindopril salts, a process for their preparation, especially industrial preparation, and their use in the therapy of hypertension |
EP06813152.3A EP1948224B1 (en) | 2005-11-17 | 2006-11-08 | Stable formulation of amorphous perindopril salts, a process for their preparation, especially industrial preparation, and their use in the therapy of hypertension |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1948224T3 true PL1948224T3 (pl) | 2014-10-31 |
Family
ID=37801135
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL06813152T PL1948224T3 (pl) | 2005-11-17 | 2006-11-08 | Trwały preparat amorficznych soli peryndoprylu, sposób ich wytwarzania, zwłaszcza wytwarzania w skali przemysłowej oraz ich zastosowanie w terapii nadciśnienia |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1948224B1 (pl) |
HR (1) | HRP20140476T1 (pl) |
ME (1) | ME01879B (pl) |
PL (1) | PL1948224T3 (pl) |
PT (1) | PT1948224E (pl) |
RS (1) | RS53324B (pl) |
RU (1) | RU2429878C2 (pl) |
SI (1) | SI1948224T1 (pl) |
WO (1) | WO2007058634A1 (pl) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI22542A (sl) * | 2007-06-04 | 2008-12-31 | Diagen D.O.O. | Stabilna formulacija amorfnih soli perindoprila, postopek za njeno pripravo v industrijskem merilu in njena uporaba za zdravljenje hipertenzije |
SI22543A (sl) | 2007-06-27 | 2008-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nove soli perindoprila |
MX2020009699A (es) | 2009-04-03 | 2021-12-17 | Ocera Therapeutics Inc | Fenil acetato de l-ornitina y metodos para elaborar el mismo. |
JP6087284B2 (ja) | 2010-10-06 | 2017-03-01 | オセラ セラピューティクス, インコーポレイテッド | L−オルニチンフェニルアセテートを製造するための方法 |
WO2016178591A2 (en) | 2015-05-05 | 2016-11-10 | Gene Predit, Sa | Genetic markers and treatment of male obesity |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4743450A (en) * | 1987-02-24 | 1988-05-10 | Warner-Lambert Company | Stabilized compositions |
SI9111842A (sl) * | 1991-11-25 | 1998-04-30 | Krka | Stabilna formulacija soli enalaprila, postopek za njeno pripravo in njena uporaba |
US5573780A (en) * | 1995-08-04 | 1996-11-12 | Apotex Usa Inc. | Stable solid formulation of enalapril salt and process for preparation thereof |
US20040014680A1 (en) * | 2000-10-16 | 2004-01-22 | Hiroaki Nakagami | Medicinal compositions quickly disintegrating in the oral cavity and process for producing the same |
WO2003075842A2 (en) * | 2002-03-08 | 2003-09-18 | Teva Pharmeceuticals Usa, Inc. | Stable formulations of angiotensin converting enzyme (ace) inhibitors |
SI21703A (en) * | 2004-01-14 | 2005-08-31 | Lek Farmacevtska Druzba Dd | Inclusion complexes of perindopril, procedure of their preparation, pharmaceutical compositions containing these complexes and their application in treatment of hypertensia |
SI21704A (en) * | 2004-01-14 | 2005-08-31 | Lek Farmacevtska Druzba Dd | New crystal form of perindopril, procedure of its preparation, pharmaceutical preparations containing this form and their application in treatment of hypertensia |
EP1729739B1 (en) | 2004-03-29 | 2016-09-28 | Les Laboratoires Servier | Process for preparing a solid pharmaceutical composition |
-
2006
- 2006-11-08 PT PT68131523T patent/PT1948224E/pt unknown
- 2006-11-08 PL PL06813152T patent/PL1948224T3/pl unknown
- 2006-11-08 EP EP06813152.3A patent/EP1948224B1/en active Active
- 2006-11-08 RU RU2008123615/15A patent/RU2429878C2/ru not_active IP Right Cessation
- 2006-11-08 WO PCT/SI2006/000034 patent/WO2007058634A1/en active Application Filing
- 2006-11-08 ME MEP-2014-54A patent/ME01879B/me unknown
- 2006-11-08 RS RS20140267A patent/RS53324B/en unknown
- 2006-11-08 SI SI200631785T patent/SI1948224T1/sl unknown
-
2014
- 2014-05-28 HR HRP20140476TT patent/HRP20140476T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
SI1948224T1 (sl) | 2014-07-31 |
RU2429878C2 (ru) | 2011-09-27 |
EP1948224A1 (en) | 2008-07-30 |
HRP20140476T1 (hr) | 2014-07-18 |
EP1948224B1 (en) | 2014-03-12 |
RS53324B (en) | 2014-10-31 |
PT1948224E (pt) | 2014-06-12 |
RU2008123615A (ru) | 2009-12-27 |
WO2007058634A1 (en) | 2007-05-24 |
WO2007058634B1 (en) | 2007-07-26 |
ME01879B (me) | 2014-12-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1095146A1 (en) | Aminopyrimidine compounds and their salts, process for preparation and pharmaceutical use thereof | |
IL192053A (en) | 2-Admentiluria derivatives as selective inhibitors of 1hsd-β11 and their use in drug preparation | |
IL233925A0 (en) | Pharmaceutical dose for oral administration in the form of tiny particles to prevent incorrect use | |
IL196854A (en) | Indole compounds and their appropriate pharmaceutical salts and their use in the preparation of @ drugs | |
EP1928802B8 (de) | In wasser redispergierbares pulver, verfahren zu dessen herstellung und dessen verwendung | |
HK1118798A1 (en) | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof -n- | |
IL216516A0 (en) | Nitrooxy derivatives of glucocorticoids, process for their preparation and use thereof in the manufacture of medicaments | |
HUP0500921A2 (en) | Tetrazole derivatives, process for their preparation and their use | |
SI1718340T1 (sl) | Novi efektorski konjugati, postopek za njihovo proizvodnjo in njihova farmacevtska uporaba | |
SI2020410T1 (sl) | Derivati pirido(2,3-d)pirimidina, njihova priprava, njihova terapevtska uporaba | |
ZA200808754B (en) | Tetrahydronaphthaline derivatives, methods for the production and use hereof as anti-inflammatory agents | |
PT1948224E (pt) | Preparação industrial, e a sua utilização na terapêutica da hipertensão | |
IL183163A0 (en) | Sulfonamido-macrocycles as tie2 inhibitors and the salts thereof, a pharmaceutical composition comprising these compounds, the method of preparing and the use thereof | |
SI1753720T1 (sl) | Postopek za pripravo perindoprila in njegovih soli | |
ZA200803445B (en) | 6-heteroarylpyridoindolone derivatives, their preparation and therapeutic use thereof | |
IL190596A0 (en) | 9-chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments | |
IL198481A0 (en) | Pyrrole derivatives, preparation use of the same in therapy | |
IL190334A0 (en) | Pyridylsulfonamide derivatives, their manufacture and use as antineoplastic agents | |
ZA200803889B (en) | Stable formulation of amorphous perindopril salts, a process for their preparation, especially industrial preparation, and their use in the therapy of hypertension | |
IL188185A0 (en) | Phenylpyridine derivatives, their manufacture and use as pharmaceutical agents | |
IL187419A0 (en) | Heteroarylethenyl derivatives, their manufacture and use as pharmaceutical agents | |
EP1743896A3 (en) | A process for the purification of imiquimod | |
AU2005905699A0 (en) | Salts and process for preparing same | |
AU2004905892A0 (en) | Salts and process for preparing same | |
GB0807094D0 (en) | 4,4-dimethylpiperidine-2, 6-dione derivatives for use in the treatment of hypertension |