SI2020410T1 - Derivati pirido(2,3-d)pirimidina, njihova priprava, njihova terapevtska uporaba - Google Patents

Derivati pirido(2,3-d)pirimidina, njihova priprava, njihova terapevtska uporaba

Info

Publication number
SI2020410T1
SI2020410T1 SI200631750T SI200631750T SI2020410T1 SI 2020410 T1 SI2020410 T1 SI 2020410T1 SI 200631750 T SI200631750 T SI 200631750T SI 200631750 T SI200631750 T SI 200631750T SI 2020410 T1 SI2020410 T1 SI 2020410T1
Authority
SI
Slovenia
Prior art keywords
pyridoš2
dćpyrimidine
derivatives
preparation
therapeutical use
Prior art date
Application number
SI200631750T
Other languages
English (en)
Inventor
Bernard Bourrie
Pierre Casellas
Samir Jegham
Claude Muneaux
Pierre Perreaut
Original Assignee
Sanofi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi filed Critical Sanofi
Publication of SI2020410T1 publication Critical patent/SI2020410T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
SI200631750T 2005-07-01 2006-06-29 Derivati pirido(2,3-d)pirimidina, njihova priprava, njihova terapevtska uporaba SI2020410T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0507032A FR2887882B1 (fr) 2005-07-01 2005-07-01 Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique
EP08017944.3A EP2020410B1 (fr) 2005-07-01 2006-06-29 Dérivés de pyrido[2,3-d] pyrimidine, leur préparation, leur application en thérapeutique

Publications (1)

Publication Number Publication Date
SI2020410T1 true SI2020410T1 (sl) 2014-04-30

Family

ID=36096420

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200631750T SI2020410T1 (sl) 2005-07-01 2006-06-29 Derivati pirido(2,3-d)pirimidina, njihova priprava, njihova terapevtska uporaba
SI200630273T SI1902054T1 (sl) 2005-07-01 2006-06-29 Derivati pirido(2,3-d)pirimidina, njihova priprava, njihova terapevtska uporaba

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200630273T SI1902054T1 (sl) 2005-07-01 2006-06-29 Derivati pirido(2,3-d)pirimidina, njihova priprava, njihova terapevtska uporaba

Country Status (41)

Country Link
US (2) US7504406B2 (sl)
EP (2) EP2020410B1 (sl)
JP (1) JP4472009B2 (sl)
KR (1) KR101298344B1 (sl)
CN (2) CN101213196B (sl)
AR (1) AR054812A1 (sl)
AT (1) ATE423119T1 (sl)
AU (1) AU2006264801B2 (sl)
BR (1) BRPI0613020A2 (sl)
CA (1) CA2610794C (sl)
CR (1) CR9568A (sl)
CY (2) CY1110457T1 (sl)
DE (1) DE602006005246D1 (sl)
DK (2) DK1902054T3 (sl)
DO (1) DOP2006000145A (sl)
EA (1) EA014312B1 (sl)
EC (1) ECSP078011A (sl)
ES (2) ES2322101T3 (sl)
FR (1) FR2887882B1 (sl)
HK (1) HK1122797A1 (sl)
HR (2) HRP20090236T1 (sl)
IL (1) IL187900A0 (sl)
JO (1) JO2550B1 (sl)
MA (1) MA29561B1 (sl)
ME (1) ME01813B (sl)
MX (1) MX2007016239A (sl)
MY (1) MY143089A (sl)
NO (1) NO20080418L (sl)
NZ (1) NZ564072A (sl)
PA (1) PA8684801A1 (sl)
PE (1) PE20070139A1 (sl)
PL (2) PL2020410T3 (sl)
PT (2) PT1902054E (sl)
RS (2) RS53211B (sl)
SI (2) SI2020410T1 (sl)
TN (1) TNSN07440A1 (sl)
TW (1) TWI321566B (sl)
UA (1) UA92021C2 (sl)
UY (1) UY29645A1 (sl)
WO (1) WO2007003765A1 (sl)
ZA (1) ZA200711032B (sl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2873118B1 (fr) 2004-07-15 2007-11-23 Sanofi Synthelabo Derives de pyrido-pyrimidine, leur application en therapeutique
FR2887882B1 (fr) * 2005-07-01 2007-09-07 Sanofi Aventis Sa Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique
FR2896246B1 (fr) 2006-01-13 2008-08-15 Sanofi Aventis Sa Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.
FR2910813B1 (fr) * 2006-12-28 2009-02-06 Sanofi Aventis Sa Nouvelle utilisation therapeutique pour le traitement des leucemies
WO2010042998A1 (en) 2008-10-17 2010-04-22 Akaal Pharma Pty Ltd S1p receptors modulators
CA2740484C (en) 2008-10-17 2021-09-21 Akaal Pharma Pty Ltd S1p receptors modulators and their use thereof
FR2948568B1 (fr) * 2009-07-30 2012-08-24 Sanofi Aventis Formulation pharmaceutique
CN103204822B (zh) * 2012-01-17 2014-12-03 上海科州药物研发有限公司 作为蛋白激酶抑制剂的苯并噁唑化合物及其制备方法和用途
EP2638911A1 (en) 2012-03-14 2013-09-18 Sanofi Novel combinations for treating acute myeloid leukaemia or chronic myeloid leukaemia
CN103833771A (zh) * 2012-11-22 2014-06-04 天津滨江药物研发有限公司 作为蛋白激酶Mek抑制剂的苯并五元杂环化合物及其制备方法和用途

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1171218A (en) 1967-11-09 1969-11-19 Parke Davis & Co New Heterocyclic Amine Compounds and Methods for their Production
JPH04128276A (ja) 1990-09-19 1992-04-28 Pfizer Pharmaceut Co Ltd アミノベンゾサルタム誘導体およびその用途
DE69515898T2 (de) * 1994-11-14 2000-08-17 Warner Lambert Co 6-ARYL-PYRIDO[2,3-d]PYRIMIDINE UND -NAPHTHYRIDINE ZUR HEMMUNG DER DURCH PROTEIN-TYROSIN-KINASE HERVORGERUFENEN ZELLVERMEHRUNG
IL115256A0 (en) 1994-11-14 1995-12-31 Warner Lambert Co 6-Aryl pyrido (2,3-d) pyrimidines and naphthyridines and their use
US5620981A (en) 1995-05-03 1997-04-15 Warner-Lambert Company Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation
IL117923A (en) 1995-05-03 2000-06-01 Warner Lambert Co Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds
AR030044A1 (es) * 2000-01-25 2003-08-13 Warner Lambert Co Pirido (2,3-d ) pirimidin-2,7-diaminas inhibidores de quinasas
EE200200506A (et) * 2000-03-06 2004-02-16 Warner-Lambert Company 5-alküülpürido[2,3-d]pürimidiinid kui türosiinkinaasi inhibiitorid
BR0112857A (pt) 2000-08-04 2005-02-09 Warner Lambert Co Compostos 2-(4-piridil)amino-6-dialcoxifenil-pirido-[2,3-d]pirimidin- 7-onas
AU2002324450A1 (en) * 2001-06-21 2003-01-08 Ariad Pharmaceuticals, Inc. Novel pyridopyrimidines and uses thereof
AU2002952453A0 (en) * 2002-11-01 2002-11-21 Novogen Research Pty Ltd Aminated isoflavonoid derivatives and uses thereof
WO2004063195A1 (en) 2003-01-03 2004-07-29 Sloan-Kettering Institute For Cancer Research Pyridopyrimidine kinase inhibitors
TW200502236A (en) * 2003-03-28 2005-01-16 Hoffmann La Roche Novel pyrido[2,3-d]pyrimidin-7-carboxylic acid derivatives, their manufacture and use as pharmaceutical agents
WO2005105097A2 (en) 2004-04-28 2005-11-10 Gpc Biotech Ag Pyridopyrimidines for treating inflammatory and other diseases
FR2873118B1 (fr) 2004-07-15 2007-11-23 Sanofi Synthelabo Derives de pyrido-pyrimidine, leur application en therapeutique
FR2887882B1 (fr) * 2005-07-01 2007-09-07 Sanofi Aventis Sa Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique
FR2896246B1 (fr) 2006-01-13 2008-08-15 Sanofi Aventis Sa Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.
US8338435B2 (en) * 2006-07-20 2012-12-25 Gilead Sciences, Inc. Substituted pyrido(3,2-D) pyrimidines and pharmaceutical compositions for treating viral infections

Also Published As

Publication number Publication date
DK2020410T3 (en) 2014-03-24
EP1902054B1 (fr) 2009-02-18
CN101213196B (zh) 2011-09-07
AR054812A1 (es) 2007-07-18
JP4472009B2 (ja) 2010-06-02
DE602006005246D1 (de) 2009-04-02
US20080176874A1 (en) 2008-07-24
EP2020410B1 (fr) 2013-12-18
PE20070139A1 (es) 2007-03-07
CN102260258A (zh) 2011-11-30
TNSN07440A1 (en) 2009-03-17
TW200745102A (en) 2007-12-16
HRP20090236T1 (en) 2009-05-31
CY1110457T1 (el) 2015-04-29
FR2887882B1 (fr) 2007-09-07
EA200800223A1 (ru) 2008-06-30
CN101213196A (zh) 2008-07-02
FR2887882A1 (fr) 2007-01-05
EP1902054A1 (fr) 2008-03-26
EA014312B1 (ru) 2010-10-29
CA2610794A1 (fr) 2007-01-11
CA2610794C (fr) 2012-02-21
PA8684801A1 (es) 2007-01-17
ES2322101T3 (es) 2009-06-16
ZA200711032B (en) 2009-04-29
RS53211B (en) 2014-08-29
UA92021C2 (ru) 2010-09-27
DK1902054T3 (da) 2009-06-15
ME01813B (me) 2014-09-20
MA29561B1 (fr) 2008-06-02
CR9568A (es) 2008-02-20
ECSP078011A (es) 2008-01-23
NO20080418L (no) 2008-03-28
AU2006264801A1 (en) 2007-01-11
ES2450067T3 (es) 2014-03-21
TWI321566B (en) 2010-03-11
PT1902054E (pt) 2009-04-22
PT2020410E (pt) 2014-03-20
JP2008544975A (ja) 2008-12-11
ATE423119T1 (de) 2009-03-15
KR101298344B1 (ko) 2013-08-20
JO2550B1 (en) 2010-09-05
AU2006264801B2 (en) 2012-05-10
CN102260258B (zh) 2015-01-07
EP2020410A1 (fr) 2009-02-04
HK1122797A1 (en) 2009-05-29
UY29645A1 (es) 2007-01-31
US8008310B2 (en) 2011-08-30
HRP20140246T1 (hr) 2014-06-20
WO2007003765A1 (fr) 2007-01-11
IL187900A0 (en) 2008-03-20
SI1902054T1 (sl) 2009-06-30
US20090163522A1 (en) 2009-06-25
DOP2006000145A (es) 2008-01-31
US7504406B2 (en) 2009-03-17
KR20080021714A (ko) 2008-03-07
PL1902054T3 (pl) 2009-07-31
MY143089A (en) 2011-03-15
PL2020410T3 (pl) 2014-05-30
BRPI0613020A2 (pt) 2010-12-14
MX2007016239A (es) 2008-03-06
RS50781B (sr) 2010-08-31
NZ564072A (en) 2012-02-24
CY1114989T1 (el) 2016-12-14

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