FR2896246B1 - Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique. - Google Patents

Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.

Info

Publication number
FR2896246B1
FR2896246B1 FR0600298A FR0600298A FR2896246B1 FR 2896246 B1 FR2896246 B1 FR 2896246B1 FR 0600298 A FR0600298 A FR 0600298A FR 0600298 A FR0600298 A FR 0600298A FR 2896246 B1 FR2896246 B1 FR 2896246B1
Authority
FR
France
Prior art keywords
pyrido
preparation
therapeutic application
pyrimidone derivatives
pyrimidone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0600298A
Other languages
English (en)
Other versions
FR2896246A1 (fr
Inventor
Pierre Perreaut
Samir Jegham
Jean Robert Labrosse
Bernard Bourrie
Pierre Casellas
Florence Durand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Priority to FR0600298A priority Critical patent/FR2896246B1/fr
Priority to JP2008549907A priority patent/JP2009523159A/ja
Priority to EP07717935A priority patent/EP1979352A2/fr
Priority to PCT/FR2007/000050 priority patent/WO2007080324A2/fr
Publication of FR2896246A1 publication Critical patent/FR2896246A1/fr
Priority to US12/166,431 priority patent/US7842806B2/en
Application granted granted Critical
Publication of FR2896246B1 publication Critical patent/FR2896246B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
FR0600298A 2006-01-13 2006-01-13 Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique. Expired - Fee Related FR2896246B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR0600298A FR2896246B1 (fr) 2006-01-13 2006-01-13 Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.
JP2008549907A JP2009523159A (ja) 2006-01-13 2007-01-12 ピリドピリミドン誘導体、これらの調製、これらの治療上の使用
EP07717935A EP1979352A2 (fr) 2006-01-13 2007-01-12 Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.
PCT/FR2007/000050 WO2007080324A2 (fr) 2006-01-13 2007-01-12 Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.
US12/166,431 US7842806B2 (en) 2006-01-13 2008-07-02 Pyridopyrimidone derivatives, preparation thereof, therapeutic use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0600298A FR2896246B1 (fr) 2006-01-13 2006-01-13 Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.

Publications (2)

Publication Number Publication Date
FR2896246A1 FR2896246A1 (fr) 2007-07-20
FR2896246B1 true FR2896246B1 (fr) 2008-08-15

Family

ID=36678623

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0600298A Expired - Fee Related FR2896246B1 (fr) 2006-01-13 2006-01-13 Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique.

Country Status (5)

Country Link
US (1) US7842806B2 (fr)
EP (1) EP1979352A2 (fr)
JP (1) JP2009523159A (fr)
FR (1) FR2896246B1 (fr)
WO (1) WO2007080324A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2873118B1 (fr) 2004-07-15 2007-11-23 Sanofi Synthelabo Derives de pyrido-pyrimidine, leur application en therapeutique
FR2887882B1 (fr) 2005-07-01 2007-09-07 Sanofi Aventis Sa Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique
FR2910813B1 (fr) 2006-12-28 2009-02-06 Sanofi Aventis Sa Nouvelle utilisation therapeutique pour le traitement des leucemies
WO2015019037A1 (fr) * 2013-08-05 2015-02-12 Almac Discovery Limited Composés pharmaceutiques
GB201322602D0 (en) 2013-12-19 2014-02-05 Almac Discovery Ltd Pharmaceutical compounds
WO2016015597A1 (fr) 2014-07-26 2016-02-04 Sunshine Lake Pharma Co., Ltd. Composés utilisés comme petits molécules inhibitrices de cdk et leurs utilisations
EP3191099B1 (fr) * 2014-09-12 2018-11-14 Biolab Sanus Farmacéutica Ltda Nouveaux composés dérivés de pyridopyrimidines

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1171218A (en) * 1967-11-09 1969-11-19 Parke Davis & Co New Heterocyclic Amine Compounds and Methods for their Production
WO1996015128A2 (fr) 1994-11-14 1996-05-23 Warner-Lambert Company 6-ARYLE PYRIDO[2,3-d]PYRIMIDINES ET NAPHTYRIDINES DESTINEES A L'INHIBITION DE LA PROLIFERATION CELLULAIRE INDUITE PAR PROTEINE TYROSINE KINASE
IL115256A0 (en) * 1994-11-14 1995-12-31 Warner Lambert Co 6-Aryl pyrido (2,3-d) pyrimidines and naphthyridines and their use
IL117923A (en) * 1995-05-03 2000-06-01 Warner Lambert Co Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds
US5620981A (en) * 1995-05-03 1997-04-15 Warner-Lambert Company Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation
US7115750B1 (en) 1999-09-20 2006-10-03 Takeda Pharmaceutical Company Limited Melanin concentrating hormone antagonist
EE200200405A (et) 2000-01-25 2003-12-15 Warner-Lambert Company Pürido[2,3-d]pürimidiin-2,7-diamiinid kui kinaasiinhibiitorid
SK12472002A3 (sk) 2000-03-06 2003-04-01 Warner-Lambert Company 5-Alkylpyrido[2,3-d]pyrimidínové inhibítory tyrosínových kináz
ATE408613T1 (de) * 2000-08-04 2008-10-15 Warner Lambert Co 2-(4-pyridyl)amino-6-dialkoxyphenyl-pyrido(2,3- d)pyrimidin-7-one
US20030105115A1 (en) 2001-06-21 2003-06-05 Metcalf Chester A. Novel pyridopyrimidines and uses thereof
US20050009849A1 (en) * 2003-01-03 2005-01-13 Veach Darren R. Pyridopyrimidine kinase inhibitors
TW200502236A (en) 2003-03-28 2005-01-16 Hoffmann La Roche Novel pyrido[2,3-d]pyrimidin-7-carboxylic acid derivatives, their manufacture and use as pharmaceutical agents
WO2005105097A2 (fr) * 2004-04-28 2005-11-10 Gpc Biotech Ag Derives de pyridopyrimidine
FR2873118B1 (fr) 2004-07-15 2007-11-23 Sanofi Synthelabo Derives de pyrido-pyrimidine, leur application en therapeutique
UY29017A1 (es) 2004-07-16 2006-02-24 Boehringer Ingelheim Int Inhibidores de polimerasa viral
FR2887882B1 (fr) 2005-07-01 2007-09-07 Sanofi Aventis Sa Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique

Also Published As

Publication number Publication date
FR2896246A1 (fr) 2007-07-20
US20090048277A1 (en) 2009-02-19
EP1979352A2 (fr) 2008-10-15
WO2007080324A2 (fr) 2007-07-19
JP2009523159A (ja) 2009-06-18
US7842806B2 (en) 2010-11-30
WO2007080324A3 (fr) 2007-08-30

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Effective date: 20120928