NO20064336L - Benzopyranforbindelser - Google Patents

Benzopyranforbindelser

Info

Publication number
NO20064336L
NO20064336L NO20064336A NO20064336A NO20064336L NO 20064336 L NO20064336 L NO 20064336L NO 20064336 A NO20064336 A NO 20064336A NO 20064336 A NO20064336 A NO 20064336A NO 20064336 L NO20064336 L NO 20064336L
Authority
NO
Norway
Prior art keywords
group
hydrogen atom
alkyl group
alkyl
integer
Prior art date
Application number
NO20064336A
Other languages
English (en)
Inventor
Toru Tsukagoshi
Takayuki Nagatsuka
Tomoyuki Matsuda
Norio Hashimoto
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Publication of NO20064336L publication Critical patent/NO20064336L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/723,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Denne oppfinnelsen vedrører benzopyranforbindelser med formel (I) hvori X er NR6, Y er en binding, SO eller SO2, Z er C1-4alkylgruppe eller fenylgruppe, W er hydrogenatom, hydroksygruppe, C1-6alkoksygruppe, et halogenatom, C1-4alkylgruppe eller C1-6alkylsulfonylaminogruppe, R1 og R2 er uavhengig av hverandre C1-3alkylgruppe, R3 er hydrogenatom, hydroksygruppe eller metoksygruppe, m er et heltall på 0 til 4, n er et heltall på 0 til 4, V er en enkel binding, CR7R8, NR9, O, S, SO eller SO2, R4 er hydrogenatom eller C1-6alkylgruppe, R5 er hydrogenatom, C1-6alkylgruppe, C3-8cykloalkylgruppe, C3-8cykloalkenylgruppe, C6-14arylgruppe eller C2-9heteroarylgruppe. Disse forbindelsene er nyttige som anti-artymimiddel.
NO20064336A 2004-02-25 2006-09-25 Benzopyranforbindelser NO20064336L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004048842 2004-02-25
PCT/JP2005/003690 WO2005080368A2 (en) 2004-02-25 2005-02-25 Benzopyran compound useful for the treatment of arrhytmia

Publications (1)

Publication Number Publication Date
NO20064336L true NO20064336L (no) 2006-09-25

Family

ID=34879527

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20064336A NO20064336L (no) 2004-02-25 2006-09-25 Benzopyranforbindelser

Country Status (21)

Country Link
US (1) US7781483B2 (no)
EP (1) EP1718629B1 (no)
JP (1) JP4798378B2 (no)
KR (1) KR101010676B1 (no)
CN (1) CN1980910B (no)
AU (1) AU2005214276B8 (no)
BR (1) BRPI0506609A (no)
CA (1) CA2557395C (no)
CZ (1) CZ2006517A3 (no)
EG (1) EG25913A (no)
ES (1) ES2401587T3 (no)
HK (1) HK1097831A1 (no)
IL (1) IL177673A (no)
NO (1) NO20064336L (no)
NZ (1) NZ549494A (no)
RU (1) RU2366658C2 (no)
SK (1) SK288112B6 (no)
TW (1) TWI346112B (no)
UA (1) UA90856C2 (no)
WO (1) WO2005080368A2 (no)
ZA (1) ZA200606971B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2003135A4 (en) 2006-03-10 2011-03-02 Nissan Chemical Ind Ltd PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMENE OXIDE COMPOUND
TW201022223A (en) * 2008-08-14 2010-06-16 Nissan Chemical Ind Ltd Di-substituted benzopyrane compound
JP2014533258A (ja) 2011-11-15 2014-12-11 ゼンション・リミテッドXention Limited カリウムチャネル阻害剤としてのチエノ[2,3−c]ピラゾールの使用
AR090037A1 (es) 2011-11-15 2014-10-15 Xention Ltd Derivados de tieno y/o furo-pirimidinas y piridinas inhibidores de los canales de potasio
TWI633095B (zh) * 2013-03-08 2018-08-21 賽諾菲公司 經取代-6-基氧基-環烷類及其作為醫藥品之用途
CN113543849A (zh) * 2018-12-28 2021-10-22 国立大学法人大阪大学 遗传性缓慢性心律失常治疗药

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZM7682A1 (en) 1981-09-25 1983-05-23 Beecham Group Plc Active compounds
DE3368057D1 (en) * 1982-05-21 1987-01-15 Beecham Group Plc Pharmaceutically active aminobenzopyrans
GB8521857D0 (en) * 1985-09-03 1985-10-09 Beecham Group Plc Active compounds
ES2030627A6 (es) * 1990-11-28 1992-11-01 Uriach & Cia Sa J Procedimiento para la obtencion de compuestos benzopiranicos.
JPH09235227A (ja) 1995-12-25 1997-09-09 Nissan Chem Ind Ltd 心不全治療薬
NZ333870A (en) 1996-07-26 2000-08-25 Nissan Chemical Ind Ltd 4-amino substituted chroman derivatives
DE69921815T2 (de) 1998-06-03 2005-11-10 Nissan Chemical Industries, Ltd. Indanderivate
WO2000012492A1 (en) 1998-09-01 2000-03-09 Nissan Chemical Industries, Ltd. Benzoxazine derivatives
WO2000058300A1 (fr) 1999-03-25 2000-10-05 Nissan Chemical Industries, Ltd. Derives du chroman
ATE311378T1 (de) 1999-09-17 2005-12-15 Nissan Chemical Ind Ltd Benzopyran derivate
AU7319800A (en) 1999-09-24 2001-04-24 Nissan Chemical Industries Ltd. 4-oxybenzopyran derivative
EP1218367A1 (en) 1999-10-05 2002-07-03 Nissan Chemical Industries, Ltd. 4-oxybenzopyran derivative
CN1198804C (zh) * 2000-03-16 2005-04-27 三菱制药株式会社 酰胺化合物及其用途
TW589305B (en) 2001-02-14 2004-06-01 Nissan Chemical Ind Ltd 4-aminobenzopyran derivatives
ATE305930T1 (de) 2001-06-25 2005-10-15 Nissan Chemical Ind Ltd Substituierte benzopyran derivate gegen arrhythmie
WO2003014113A1 (en) 2001-08-06 2003-02-20 Glenmark Pharmaceuticals Limited Novel benzopyran compounds and process for their preparation and use

Also Published As

Publication number Publication date
AU2005214276A1 (en) 2005-09-01
ZA200606971B (en) 2009-01-28
SK50712006A3 (sk) 2007-07-06
RU2006133931A (ru) 2008-03-27
EG25913A (en) 2012-10-10
CN1980910B (zh) 2012-06-13
CZ2006517A3 (cs) 2006-11-15
CA2557395A1 (en) 2005-09-01
CN1980910A (zh) 2007-06-13
TW200533660A (en) 2005-10-16
UA90856C2 (ru) 2010-06-10
KR20070032300A (ko) 2007-03-21
BRPI0506609A (pt) 2007-05-02
SK288112B6 (sk) 2013-08-02
US20070299130A1 (en) 2007-12-27
IL177673A (en) 2013-03-24
JP2007523885A (ja) 2007-08-23
HK1097831A1 (en) 2007-07-06
KR101010676B1 (ko) 2011-01-24
NZ549494A (en) 2010-06-25
TWI346112B (en) 2011-08-01
WO2005080368A2 (en) 2005-09-01
WO2005080368A3 (en) 2005-11-10
IL177673A0 (en) 2006-12-31
AU2005214276B2 (en) 2010-05-20
AU2005214276B8 (en) 2010-06-10
CA2557395C (en) 2011-01-18
EP1718629B1 (en) 2012-12-26
JP4798378B2 (ja) 2011-10-19
ES2401587T3 (es) 2013-04-22
US7781483B2 (en) 2010-08-24
RU2366658C2 (ru) 2009-09-10
EP1718629A2 (en) 2006-11-08

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