ATE311378T1 - Benzopyran derivate - Google Patents
Benzopyran derivateInfo
- Publication number
- ATE311378T1 ATE311378T1 AT00961032T AT00961032T ATE311378T1 AT E311378 T1 ATE311378 T1 AT E311378T1 AT 00961032 T AT00961032 T AT 00961032T AT 00961032 T AT00961032 T AT 00961032T AT E311378 T1 ATE311378 T1 AT E311378T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- hydrogen atom
- alkyl group
- substituted
- absent
- Prior art date
Links
- 150000001562 benzopyrans Chemical class 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 5
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- -1 (substituted)phenyl group Chemical group 0.000 abstract 1
- KYNSBQPICQTCGU-UHFFFAOYSA-N Benzopyrane Chemical compound C1=CC=C2C=CCOC2=C1 KYNSBQPICQTCGU-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000005196 alkyl carbonyloxy group Chemical group 0.000 abstract 1
- 239000003416 antiarrhythmic agent Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000036747 functional refractory period Effects 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP26445599 | 1999-09-17 | ||
| PCT/JP2000/006323 WO2001021610A1 (en) | 1999-09-17 | 2000-09-14 | Benzopyran derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE311378T1 true ATE311378T1 (de) | 2005-12-15 |
Family
ID=17403453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00961032T ATE311378T1 (de) | 1999-09-17 | 2000-09-14 | Benzopyran derivate |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6589983B1 (de) |
| EP (1) | EP1212314B1 (de) |
| KR (1) | KR100766676B1 (de) |
| CN (1) | CN1167697C (de) |
| AT (1) | ATE311378T1 (de) |
| AU (1) | AU766935B2 (de) |
| CA (1) | CA2383583C (de) |
| CZ (1) | CZ2002802A3 (de) |
| DE (1) | DE60024471T2 (de) |
| HK (1) | HK1047106B (de) |
| HU (1) | HUP0202690A3 (de) |
| IL (2) | IL147968A0 (de) |
| NO (1) | NO328013B1 (de) |
| NZ (1) | NZ517404A (de) |
| RU (1) | RU2234502C2 (de) |
| SK (1) | SK3292002A3 (de) |
| WO (1) | WO2001021610A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW589305B (en) * | 2001-02-14 | 2004-06-01 | Nissan Chemical Ind Ltd | 4-aminobenzopyran derivatives |
| FI20011507A0 (fi) | 2001-07-10 | 2001-07-10 | Orion Corp | Uusia yhdisteitä |
| JP2005505586A (ja) * | 2001-10-04 | 2005-02-24 | ワイス | ５−ヒドロキシトリプタミン−６リガンドとしてのクロマン誘導体 |
| JP4569755B2 (ja) * | 2002-08-29 | 2010-10-27 | 日産化学工業株式会社 | アミノベンゾピラン化合物の製造方法 |
| FI20030030A0 (fi) * | 2003-01-09 | 2003-01-09 | Orion Corp | Uusia yhdisteitä |
| GB0315950D0 (en) | 2003-06-11 | 2003-08-13 | Xention Discovery Ltd | Compounds |
| TWI346112B (en) * | 2004-02-25 | 2011-08-01 | Nissan Chemical Ind Ltd | Benzopyran compound |
| CN1934116B (zh) * | 2004-03-23 | 2012-10-10 | 日产化学工业株式会社 | 用作抗心律失常剂的三环苯并吡喃化合物 |
| GB0412986D0 (en) | 2004-06-10 | 2004-07-14 | Xention Discovery Ltd | Compounds |
| US7576212B2 (en) | 2004-12-09 | 2009-08-18 | Xention Limited | Thieno[2,3-B] pyridines as potassium channel inhibitors |
| BRPI0515830A (pt) * | 2004-12-21 | 2008-08-05 | F Hoffmann La Roche | derivados de cromano e usos dos mesmos no tratamento de distúrbios do sistema nervoso central |
| GB0525164D0 (en) | 2005-12-09 | 2006-01-18 | Xention Discovery Ltd | Compounds |
| KR20080112290A (ko) * | 2006-03-10 | 2008-12-24 | 닛산 가가쿠 고교 가부시키 가이샤 | 광학 활성 크로멘 옥사이드화합물의 제조 방법 |
| GB0815781D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB0815782D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB0815784D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| WO2012003476A2 (en) * | 2010-07-02 | 2012-01-05 | Ventana Medical Systems, Inc. | Hapten conjugates for target detection |
| GB201105659D0 (en) | 2011-04-01 | 2011-05-18 | Xention Ltd | Compounds |
| NO3175985T3 (de) | 2011-07-01 | 2018-04-28 | ||
| AR090037A1 (es) | 2011-11-15 | 2014-10-15 | Xention Ltd | Derivados de tieno y/o furo-pirimidinas y piridinas inhibidores de los canales de potasio |
| JP2014533258A (ja) | 2011-11-15 | 2014-12-11 | ゼンション・リミテッドＸｅｎｔｉｏｎ Ｌｉｍｉｔｅｄ | カリウムチャネル阻害剤としてのチエノ［２，３−ｃ］ピラゾールの使用 |
| WO2013112932A1 (en) | 2012-01-27 | 2013-08-01 | Gilead Sciences, Inc. | Combination therapies using late sodium ion channel blockers and potassium ion channel blockers |
| US20220071951A1 (en) | 2018-12-28 | 2022-03-10 | Osaka University | Therapeutic agent for inherited bradyarrhythmia |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9005318D0 (en) * | 1990-03-09 | 1990-05-02 | Isis Innovation | Antiarrhythmic agents |
| AU651105B2 (en) * | 1990-06-18 | 1994-07-14 | E.R. Squibb & Sons, Inc. | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents |
| GB9301611D0 (en) * | 1993-08-04 | 1993-08-04 | Parisella Gerald | Dexterity game |
| CA2261143A1 (en) * | 1996-07-26 | 1998-02-05 | Nissan Chemical Industries, Ltd. | Chroman derivatives |
-
2000
- 2000-09-14 US US10/048,026 patent/US6589983B1/en not_active Expired - Fee Related
- 2000-09-14 CZ CZ2002802A patent/CZ2002802A3/cs unknown
- 2000-09-14 AU AU73143/00A patent/AU766935B2/en not_active Ceased
- 2000-09-14 EP EP00961032A patent/EP1212314B1/de not_active Expired - Lifetime
- 2000-09-14 CN CNB008129509A patent/CN1167697C/zh not_active Expired - Fee Related
- 2000-09-14 AT AT00961032T patent/ATE311378T1/de not_active IP Right Cessation
- 2000-09-14 HU HU0202690A patent/HUP0202690A3/hu unknown
- 2000-09-14 IL IL14796800A patent/IL147968A0/xx active IP Right Grant
- 2000-09-14 KR KR1020027003510A patent/KR100766676B1/ko not_active Expired - Fee Related
- 2000-09-14 HK HK02108750.1A patent/HK1047106B/en not_active IP Right Cessation
- 2000-09-14 RU RU2002110115/04A patent/RU2234502C2/ru not_active IP Right Cessation
- 2000-09-14 WO PCT/JP2000/006323 patent/WO2001021610A1/en not_active Ceased
- 2000-09-14 SK SK329-2002A patent/SK3292002A3/sk unknown
- 2000-09-14 NZ NZ517404A patent/NZ517404A/xx unknown
- 2000-09-14 CA CA002383583A patent/CA2383583C/en not_active Expired - Fee Related
- 2000-09-14 DE DE60024471T patent/DE60024471T2/de not_active Expired - Lifetime
-
2002
- 2002-02-03 IL IL147968A patent/IL147968A/en not_active IP Right Cessation
- 2002-03-15 NO NO20021294A patent/NO328013B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US6589983B1 (en) | 2003-07-08 |
| KR20020068505A (ko) | 2002-08-27 |
| HK1047106B (en) | 2006-04-28 |
| RU2234502C2 (ru) | 2004-08-20 |
| CA2383583A1 (en) | 2001-03-29 |
| EP1212314B1 (de) | 2005-11-30 |
| CN1167697C (zh) | 2004-09-22 |
| NZ517404A (en) | 2003-01-31 |
| HUP0202690A2 (hu) | 2002-12-28 |
| NO20021294L (no) | 2002-03-15 |
| IL147968A0 (en) | 2002-09-12 |
| CA2383583C (en) | 2009-04-07 |
| EP1212314A1 (de) | 2002-06-12 |
| HK1047106A1 (en) | 2003-02-07 |
| NO20021294D0 (no) | 2002-03-15 |
| AU7314300A (en) | 2001-04-24 |
| SK3292002A3 (en) | 2003-04-01 |
| NO328013B1 (no) | 2009-11-09 |
| CZ2002802A3 (cs) | 2003-02-12 |
| DE60024471D1 (de) | 2006-01-05 |
| AU766935B2 (en) | 2003-10-23 |
| HUP0202690A3 (en) | 2005-02-28 |
| DE60024471T2 (de) | 2006-08-03 |
| IL147968A (en) | 2006-04-10 |
| CN1374957A (zh) | 2002-10-16 |
| KR100766676B1 (ko) | 2007-10-15 |
| WO2001021610A1 (en) | 2001-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |