NO20081167L - Fluoriseringsframgangsmate - Google Patents
FluoriseringsframgangsmateInfo
- Publication number
- NO20081167L NO20081167L NO20081167A NO20081167A NO20081167L NO 20081167 L NO20081167 L NO 20081167L NO 20081167 A NO20081167 A NO 20081167A NO 20081167 A NO20081167 A NO 20081167A NO 20081167 L NO20081167 L NO 20081167L
- Authority
- NO
- Norway
- Prior art keywords
- formula
- compound
- alkyl
- precursors
- fluoride
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
- C07C209/74—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton by halogenation, hydrohalogenation, dehalogenation, or dehydrohalogenation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/24—Stationary reactors without moving elements inside
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
- C07C211/45—Monoamines
- C07C211/46—Aniline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
- C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/24—Stationary reactors without moving elements inside
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Oppfinnelsen angår en framgangsmåte for framstilling av en forbindelse av formel (I): der R1 er valgt blant C1-6-alkyl, C2-6-alkenyl, og C2-6-alkynyl, som omfatter: (i) reaksjon mellom fluorid, gjerne [18F]fluorid, og en tilsvarende forbindelse av formel (II): der R2 er valgt blant hydrogen, C1-10-alkyl, C1-10-halogenalkyl, C6-14-aryl, C6-14-arylalkyl, -(CH2CH2O)q-CH3 der q er et heltall fra 1 til 10, R1 er som definert for forbindelsen av formel (I), og R3 er en utgående gruppe. Visse nye forløpere av formel (II) og radiofarmasøytiske sett som inneholder slike forløpere er også omfattet av oppfinnelsen.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0516564.2A GB0516564D0 (en) | 2005-08-12 | 2005-08-12 | Fluorination process |
PCT/GB2006/003009 WO2007020400A1 (en) | 2005-08-12 | 2006-08-11 | Fluorination process of anilide derivatives and benzothiazole fluorinate derivatives as in vivo imaging agents |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20081167L true NO20081167L (no) | 2008-03-05 |
NO341560B1 NO341560B1 (no) | 2017-12-04 |
Family
ID=35098197
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20081167A NO341560B1 (no) | 2005-08-12 | 2008-03-05 | Fluorineringsframgangsmåter, nye forbindelser, samt radiofarmasøytiske sett og kassetter |
Country Status (21)
Country | Link |
---|---|
US (3) | US8410312B2 (no) |
EP (1) | EP1915330B1 (no) |
JP (2) | JP5566605B2 (no) |
KR (2) | KR101409608B1 (no) |
CN (2) | CN101282920B (no) |
AU (1) | AU2006281216B2 (no) |
BR (1) | BRPI0614752B1 (no) |
CA (1) | CA2618448C (no) |
DK (1) | DK1915330T3 (no) |
ES (1) | ES2527864T3 (no) |
GB (1) | GB0516564D0 (no) |
HK (1) | HK1177463A1 (no) |
IL (1) | IL188933A0 (no) |
MX (2) | MX341173B (no) |
NO (1) | NO341560B1 (no) |
NZ (1) | NZ565333A (no) |
PL (1) | PL1915330T3 (no) |
PT (1) | PT1915330E (no) |
RU (1) | RU2419601C2 (no) |
WO (1) | WO2007020400A1 (no) |
ZA (1) | ZA200801860B (no) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0516564D0 (en) * | 2005-08-12 | 2005-09-21 | Ge Healthcare Ltd | Fluorination process |
WO2008106442A1 (en) * | 2007-02-27 | 2008-09-04 | Ge Healthcare Limited | Synthesis of [18f] fluoromethyl benzene using benzyl pentafluorobenzenesulfonate |
DK2182988T3 (da) * | 2007-08-30 | 2014-05-26 | Ge Healthcare Ltd | Radiofarmaceutisk præparat |
EP2238074A2 (en) | 2008-01-03 | 2010-10-13 | GE Healthcare UK Limited | Fluoride processing method |
ES2540536T3 (es) | 2008-09-23 | 2015-07-10 | Wista Laboratories Ltd. | Ligandos para moléculas tau agregadas |
GB0921967D0 (en) * | 2009-12-17 | 2010-02-03 | Ge Healthcare Ltd | Novel Aryloxyanilide Derivatives |
GB201019303D0 (en) | 2010-11-15 | 2010-12-29 | Strom Hans E P | Agents and methods for visualising analytes |
CN103613589B (zh) * | 2013-11-29 | 2016-03-30 | 江苏华益科技有限公司 | 一种用于神经退行性疾病领域的新型pet显像剂前体及标准品的合成方法 |
WO2016087653A1 (en) | 2014-12-04 | 2016-06-09 | Ge Healthcare Limited | Method of removing acetaldehyde from radioactive pharmaceuticals |
JP6485914B2 (ja) * | 2015-10-28 | 2019-03-20 | 日本メジフィジックス株式会社 | フルテメタモルの製造方法 |
JP6955347B2 (ja) | 2017-02-28 | 2021-10-27 | 日本メジフィジックス株式会社 | フルテメタモルの製造方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3878206A (en) * | 1973-06-06 | 1975-04-15 | Morton Norwich Products Inc | 9-(Substituted amino)imidazo{8 4,5-f{9 quinolines |
FR2449677B1 (fr) | 1979-02-26 | 1986-03-28 | Fabre Sa Pierre | Nouveaux derives de benzoyl-2 glycylanilides substitues, leur preparation et leur application en tant que medicaments anxiolytiques |
FR2693781B1 (fr) * | 1992-07-15 | 1994-10-28 | Otis Elevator Co | Dispositif de réglage de la tension d'un câble faisant boucle. |
DE4402056A1 (de) | 1994-01-25 | 1995-07-27 | Basf Ag | p-Phenylendiamin-Derivate und sie enthaltende fungizide Mittel |
US7270800B2 (en) * | 2000-08-24 | 2007-09-18 | University Of Pittsburgh | Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition |
GB0229686D0 (en) * | 2002-12-20 | 2003-01-29 | Amersham Plc | Solid-phase fluorination of benzothiazoles |
RU2440995C2 (ru) * | 2003-03-14 | 2012-01-27 | Юнивесити Оф Питсбэг | Производные бензотиазола, фармацевтическая композиция, обладающая свойством связывать амилоид, и способ детекции отложений амилоида у млекопитающего |
CA2438032C (en) | 2003-03-14 | 2013-05-07 | University Of Pittsburgh | Benzothiazole derivative compounds, compositions and uses |
PT1771208E (pt) * | 2004-07-02 | 2013-09-24 | Univ Pittsburgh | Utilização de derivados de tioflavina radiorotulados em imagiologia amiloide para avaliar terapias anti-amiloide |
GB0516564D0 (en) * | 2005-08-12 | 2005-09-21 | Ge Healthcare Ltd | Fluorination process |
-
2005
- 2005-08-12 GB GBGB0516564.2A patent/GB0516564D0/en not_active Ceased
-
2006
- 2006-08-11 RU RU2008103989/04A patent/RU2419601C2/ru active
- 2006-08-11 US US12/063,470 patent/US8410312B2/en active Active
- 2006-08-11 AU AU2006281216A patent/AU2006281216B2/en active Active
- 2006-08-11 WO PCT/GB2006/003009 patent/WO2007020400A1/en active Application Filing
- 2006-08-11 BR BRPI0614752-6A patent/BRPI0614752B1/pt active IP Right Grant
- 2006-08-11 JP JP2008525644A patent/JP5566605B2/ja active Active
- 2006-08-11 ES ES06765263.6T patent/ES2527864T3/es active Active
- 2006-08-11 MX MX2013013741A patent/MX341173B/es unknown
- 2006-08-11 CA CA2618448A patent/CA2618448C/en active Active
- 2006-08-11 CN CN200680037139.7A patent/CN101282920B/zh active Active
- 2006-08-11 DK DK06765263.6T patent/DK1915330T3/en active
- 2006-08-11 CN CN201210177977.1A patent/CN102731432B/zh active Active
- 2006-08-11 NZ NZ565333A patent/NZ565333A/en unknown
- 2006-08-11 KR KR1020137025584A patent/KR101409608B1/ko active IP Right Grant
- 2006-08-11 PL PL06765263T patent/PL1915330T3/pl unknown
- 2006-08-11 EP EP06765263.6A patent/EP1915330B1/en active Active
- 2006-08-11 MX MX2008002068A patent/MX2008002068A/es active IP Right Grant
- 2006-08-11 PT PT67652636T patent/PT1915330E/pt unknown
-
2008
- 2008-01-22 IL IL188933A patent/IL188933A0/en active IP Right Grant
- 2008-02-11 KR KR1020087003263A patent/KR101392538B1/ko active Protection Beyond IP Right Term
- 2008-02-27 ZA ZA200801860A patent/ZA200801860B/xx unknown
- 2008-03-05 NO NO20081167A patent/NO341560B1/no unknown
-
2013
- 2013-03-22 US US13/848,877 patent/US9126961B2/en active Active
- 2013-04-17 HK HK13104661.5A patent/HK1177463A1/zh unknown
- 2013-09-24 JP JP2013196384A patent/JP2014028837A/ja not_active Withdrawn
-
2015
- 2015-07-27 US US14/809,497 patent/US9468694B2/en active Active
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CREP | Change of representative |
Representative=s name: ZACCO NORWAY AS, POSTBOKS 2003 VIKA |