MX2009013591A - Proceso para la preparacion de pirazoles. - Google Patents

Proceso para la preparacion de pirazoles.

Info

Publication number
MX2009013591A
MX2009013591A MX2009013591A MX2009013591A MX2009013591A MX 2009013591 A MX2009013591 A MX 2009013591A MX 2009013591 A MX2009013591 A MX 2009013591A MX 2009013591 A MX2009013591 A MX 2009013591A MX 2009013591 A MX2009013591 A MX 2009013591A
Authority
MX
Mexico
Prior art keywords
processes
pyrazoles
preparation
hal
sup
Prior art date
Application number
MX2009013591A
Other languages
English (en)
Inventor
Martin Charles Bowden
David Anthony Jackson
Brian David Gott
Iacob Gutsu
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38812166&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009013591(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of MX2009013591A publication Critical patent/MX2009013591A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C07C251/74—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/76—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Abstract

La presente invención se refiere a procesos novedosos para la producción de compuestos de la fórmula (ver fórmula) en los cuales Hal y Hal´ se seleccionan en forma independiente entre Cl y F, y R1 se selecciona entre Cl, F y H.
MX2009013591A 2007-06-27 2008-06-16 Proceso para la preparacion de pirazoles. MX2009013591A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07012546A EP2008996A1 (en) 2007-06-27 2007-06-27 Process for the production of pyrazoles
PCT/EP2008/004829 WO2009000441A1 (en) 2007-06-27 2008-06-16 Processes for the preparation of pyrazoles

Publications (1)

Publication Number Publication Date
MX2009013591A true MX2009013591A (es) 2010-01-20

Family

ID=38812166

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2009013592A MX2009013592A (es) 2007-06-27 2008-06-16 Proceso para la preparacion de pirazoles.
MX2009013591A MX2009013591A (es) 2007-06-27 2008-06-16 Proceso para la preparacion de pirazoles.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2009013592A MX2009013592A (es) 2007-06-27 2008-06-16 Proceso para la preparacion de pirazoles.

Country Status (18)

Country Link
US (3) US8269020B2 (es)
EP (3) EP2008996A1 (es)
JP (2) JP2010531315A (es)
KR (2) KR20100025531A (es)
CN (3) CN101687806A (es)
AR (2) AR067355A1 (es)
AU (2) AU2008267473A1 (es)
BR (2) BRPI0813903A2 (es)
CA (2) CA2689218A1 (es)
CL (2) CL2008001896A1 (es)
CO (2) CO6251314A2 (es)
CR (2) CR11161A (es)
EC (2) ECSP099818A (es)
IL (2) IL202419A0 (es)
MX (2) MX2009013592A (es)
RU (2) RU2010102137A (es)
TW (2) TW200916445A (es)
WO (2) WO2009000442A2 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2008996A1 (en) * 2007-06-27 2008-12-31 Syngeta Participations AG Process for the production of pyrazoles
EP2133341A1 (de) * 2008-02-25 2009-12-16 Bayer CropScience AG Verfahren zur regioselektiven Synthese von 1-Alkyl-3-haloalkyl-pyrazol-4-carbonsäure-Derivaten
CA2735921C (en) 2008-09-30 2017-03-21 Solvay Sa Process for the synthesis of halogenated cyclic compounds
GB0908435D0 (en) * 2009-05-15 2009-06-24 Syngenta Ltd Processes
WO2012025469A1 (en) * 2010-08-24 2012-03-01 Solvay Sa Improved process for the preparation of esters of 1-h-pyrazole-4-carboxylic acids
FR2975990B1 (fr) * 2011-06-01 2013-05-24 Rhodia Operations Procede de preparation d'un compose organique fluore
FR2975992B1 (fr) * 2011-06-01 2013-11-08 Rhodia Operations Procede de preparation d'un compose fluoromethylpyrazole sous forme acide carboxylique ou derivee
EP2850066B1 (de) 2012-05-14 2016-03-16 Bayer CropScience AG Verfahren zum herstellen von 1-alkyl-3-fluoralkyl-1h-pyrazol-4-carbonsäurechloriden
US8871947B2 (en) 2013-02-04 2014-10-28 KingChem LLC Preparation of alkyl 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid ester
DK3060540T3 (en) 2013-10-23 2018-10-15 Bayer Cropscience Ag PROCEDURE FOR THE PREPARATION OF HALOGEN KETONS
CN103570623B (zh) * 2013-11-12 2015-05-20 湖南化工研究院 一种3-(二氟甲基)-1-甲基-1h-吡唑-4-羧酸的制备方法
WO2015085464A1 (en) 2013-12-09 2015-06-18 King Chem, Llc Process for preparing alkyl 3-difluoromethyl-1-methyl-1h-pyrazole-4-carboxylate and its analogs
CN103787977B (zh) * 2014-01-21 2016-05-25 南通雅本化学有限公司 一种空气氧化制备3-氟代烷基-1-取代吡唑-4-羧酸的方法
CN105541716B (zh) * 2015-03-26 2024-02-23 Ａｇｃ株式会社 吡唑衍生物的制造方法
CN104945325B (zh) * 2015-06-19 2017-04-05 浙江永太科技股份有限公司 一种吡唑甲酸衍生物的制备方法
ES2844530T3 (es) * 2015-06-19 2021-07-22 Zhejiang Yongtai Technology Co Ltd Método para preparar un derivado del ácido pirazolcarboxílico e intermedio del mismo
CN106554311B (zh) * 2015-09-28 2019-03-01 常州市卜弋科研化工有限公司 3-氟代烷基-1-甲基吡唑-4-羧酸的制备方法
WO2017054112A1 (zh) * 2015-09-28 2017-04-06 常州市卜弋科研化工有限公司 3-氟代烷基-1-甲基吡唑-4-羧酸的制备方法
EP3797099B1 (en) 2018-05-21 2023-11-01 PI Industries Ltd. Method for preparing substituted heterocyclic compounds
CN109232425A (zh) * 2018-10-16 2019-01-18 山东省农药科学研究院 一种苯丙烯氟菌唑中间体3-(二氟甲基)-1-甲基-1h-吡唑-4-羧酸的合成方法
CN110577503A (zh) 2019-08-02 2019-12-17 宿迁市科莱博生物化学有限公司 一种卤素取代化合物及其制备方法和应用
CN111233768B (zh) * 2020-03-18 2021-08-03 徐州圣元化工有限公司 一种3-(二氟甲基)-1-甲基-1h-吡唑-4-羧酸乙酯的制备方法
CN111303035A (zh) * 2020-03-18 2020-06-19 徐州圣元化工有限公司 一种3-(二氟甲基)-1-甲基-1h-吡唑-4-羧酸的制备方法
WO2022233129A1 (en) 2021-05-05 2022-11-10 Fujian Yongjing Technology Co., Ltd New process for the synthesis of 5-fluoro-3- (difuoromethyl) -5-fluoro-1-methyl-1h-pyrazole-4-carboxylic acid derivatives and the free acid thereof
CN114195715A (zh) * 2021-12-31 2022-03-18 福建永晶科技股份有限公司 1-甲基-3-二氟甲基-4-吡唑酸和1-甲基-3-三氟甲基-4-吡唑酸的制备方法
CN117384096A (zh) * 2023-12-13 2024-01-12 山东国邦药业有限公司 一种二氟吡唑酸的制备方法
CN117447401B (zh) * 2023-12-26 2024-04-19 山东国邦药业有限公司 一种二氟吡唑酸的合成方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0759558B2 (ja) * 1987-12-25 1995-06-28 三井東圧化学株式会社 １，３−ジアルキルピラゾール−４−アルデヒド類の製造法
JPH0759557B2 (ja) * 1987-12-25 1995-06-28 三井東圧化学株式会社 １，３−ジアルキルピラゾール−４−アルデヒド誘導体の製造方法
JPH089599B2 (ja) * 1988-08-02 1996-01-31 三井東圧化学株式会社 ピラゾールカルボン酸類の製造方法
AU2003295041A1 (en) * 2002-11-20 2004-06-18 L'oreal Composition for hair care or eyelashes containing a pyrazol-carboxamide, its use for stimulating hair and eyelash growth and/or for preventing loss thereof
DE10349500A1 (de) * 2003-10-23 2005-06-02 Bayer Cropscience Ag Verfahren zum Herstellen von 2-Dihalogenacyl-3-amino-acrylsäureestern und 3-Dihalogenmethyl-pyrazol-4-carbonsäureestern
ATE471320T1 (de) * 2004-02-27 2010-07-15 Lilly Co Eli 4-aminopiperidinderivate als inhibitoren der monoamin-aufnahme
WO2005123690A1 (de) * 2004-06-18 2005-12-29 Basf Aktiengesellschaft 1-methyl-3-difluormethyl-pyrazol-4-carbonsäure-(ortho-phenyl)-anilide und ihre verwendung als fungizid
BRPI0514425A (pt) * 2004-08-18 2008-06-10 Pfizer inibidores de rna polimerase dependente de rna do vìrus da hepatite c, e composições e tratamentos usando os mesmos
US7863460B2 (en) * 2005-02-25 2011-01-04 Sagami Chemical Research Center Process for producing 1-substituted-3-fluoroalkylpyrazole-4-carboxylate
EP2253623B1 (en) * 2005-09-16 2013-10-23 Syngenta Participations AG. New crystal form of a pyrazole fungicide
JP5456663B2 (ja) * 2007-06-01 2014-04-02 ビーエーエスエフ ソシエタス・ヨーロピア Ｎ−置換（３−ジハロメチル−１−メチル−ピラゾール−４−イル）カルボキサミドの製造方法
EP2008996A1 (en) * 2007-06-27 2008-12-31 Syngeta Participations AG Process for the production of pyrazoles

Also Published As

Publication number Publication date
CR11161A (es) 2010-05-19
JP2010531314A (ja) 2010-09-24
AR067356A1 (es) 2009-10-07
EP2167461B1 (en) 2012-08-08
CL2008001897A1 (es) 2009-01-02
KR20100025531A (ko) 2010-03-09
WO2009000441A8 (en) 2010-01-14
MX2009013592A (es) 2010-01-20
IL202419A0 (en) 2010-06-30
US8269020B2 (en) 2012-09-18
KR20100025533A (ko) 2010-03-09
ECSP099818A (es) 2010-01-29
JP5563449B2 (ja) 2014-07-30
TW200914428A (en) 2009-04-01
CR11162A (es) 2010-04-21
CN102516175A (zh) 2012-06-27
AR067355A1 (es) 2009-10-07
US20100240907A1 (en) 2010-09-23
BRPI0813284A2 (pt) 2014-12-30
CO6251314A2 (es) 2011-02-21
RU2010102135A (ru) 2011-08-10
CN101796021A (zh) 2010-08-04
AU2008267472A1 (en) 2008-12-31
BRPI0813284B1 (pt) 2017-10-31
EP2167461A1 (en) 2010-03-31
CO6251313A2 (es) 2011-02-21
WO2009000442A8 (en) 2010-01-21
CL2008001896A1 (es) 2009-03-06
WO2009000442A3 (en) 2009-07-23
EP2170832A2 (en) 2010-04-07
TW200916445A (en) 2009-04-16
WO2009000442A2 (en) 2008-12-31
BRPI0813284A8 (pt) 2017-04-04
ECSP099817A (es) 2010-01-29
RU2010102137A (ru) 2011-08-10
CN101687806A (zh) 2010-03-31
CA2689218A1 (en) 2008-12-31
US20100256390A1 (en) 2010-10-07
EP2008996A1 (en) 2008-12-31
US20130023668A1 (en) 2013-01-24
BRPI0813903A2 (pt) 2014-12-30
JP2010531315A (ja) 2010-09-24
CA2690246A1 (en) 2008-12-31
US8785657B2 (en) 2014-07-22
AU2008267473A1 (en) 2008-12-31
IL202664A (en) 2014-07-31
WO2009000441A1 (en) 2008-12-31
IL202664A0 (en) 2010-06-30

Similar Documents

Publication Publication Date Title
MX2009013591A (es) Proceso para la preparacion de pirazoles.
TW200635509A (en) 5-Alkoxyalkyl-6-alkyl-7-aminoazolopyrimidines, process for their preparation, their use for controlling harmful fungi, and compositions comprising them
TW200833675A (en) Nicotinamide derivatives
MX2007013632A (es) Procedimientos para preparar derivados de bencil-benceno sustituidos con glucopiranosilo y sus productos intermedios.
MX2007014172A (es) Procedimiento para la produccion de 4-bifenililacetidina-2-onas fenolicos.
HK1099688A1 (en) 1,3,5-trisubstituted 4,5-dihydro-1h-pyrazole derivatives having cb1- antagonistic activity
MX2010012529A (es) Derivados de indazol sustituidos con fenilo y benzodioxinilo.
MX2008010481A (es) Compuestos que tienen afinado para el receptor f-ht6.
MX340572B (es) Proceso para la fabricacion de compuestos farmaceuticamente activos.
MX2010001576A (es) Compuestos 3´sustituidos que tienen afinidad con el receptor 5-hidroxitriptamina 6 (5-ht6).
HK1080088A1 (zh) 製備c-7取代的5-雄甾烯的方法
AU2008303600A8 (en) 1,1,1-trifluoro-2-hydroxy-3-phenylpropane derivatives
MX2012002641A (es) Inhibidores de cinasa janus (jak).
MX2009008324A (es) Compuestos 6´-sustituidos que tienen afinidad con el receptor de 5-hidroxitriptamina-6.
TW200710084A (en) Process for the synthesis of organic compounds
MX2009012471A (es) Compuestos 4´sustituidos que tienen afinidad al receptor 5-hidroxitriptamina 6.
MX2009008028A (es) Agentes antiparasitarios.
UA100862C2 (ru) Шестичленные ароматические соединения, их получение и применение (варианты)
UA93860C2 (ru) Способ получения пиразолов, способ региоселективного алкилирования и применение фосфата или фосфоната b способе
MX2007013872A (es) Procedimiento para la produccion de 4-bifenililazetidina-2-onas.
MX2008000011A (es) Procesos para preparar derivados de pirazol-o-glucosido y nuevos intermediarios de dichos procesos.
MX2009006266A (es) Procedimientos de preparacion de 3-(4-(2,4-difluorobenciloxi)-3-br omo-6-metil-2-oxopiridin-1 (2h)-il)-n,4-dimetilbenzamida.
MX2012001067A (es) Procesos para la alquilacion de pirazoles.
MX2009013336A (es) Sintesis de 3-aminopirazoles sustituidos.
WO2011023986A8 (en) Kinase inhibitors

Legal Events

Date Code Title Description
FG Grant or registration