NO20070776L - Forbedret prosess for fremstilling av mirtazapin - Google Patents

Forbedret prosess for fremstilling av mirtazapin

Info

Publication number
NO20070776L
NO20070776L NO20070776A NO20070776A NO20070776L NO 20070776 L NO20070776 L NO 20070776L NO 20070776 A NO20070776 A NO 20070776A NO 20070776 A NO20070776 A NO 20070776A NO 20070776 L NO20070776 L NO 20070776L
Authority
NO
Norway
Prior art keywords
mirtazapine
preparation
improved process
cyclization
crystalline
Prior art date
Application number
NO20070776A
Other languages
English (en)
Inventor
Carmen Arnalot Aguilar
Original Assignee
Medichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medichem Sa filed Critical Medichem Sa
Publication of NO20070776L publication Critical patent/NO20070776L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

En forbedret prosess for fremstilling av mirtazapin. En prosess beskrives for fremstilling av mirtazapin ved å begynne fra en forbindelse med formel (II) som underkastes ringslutning, for å oppnåelse av mirtazapin for farmasøytisk anvendelse i krystallinsk og vannfri form.
NO20070776A 2004-07-22 2007-02-09 Forbedret prosess for fremstilling av mirtazapin NO20070776L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200401804A ES2246161B1 (es) 2004-07-22 2004-07-22 Proceso mejorado para la fabricacion de mirtazapina.
PCT/EP2005/053493 WO2006008302A2 (en) 2004-07-22 2005-07-19 Improved process for the manufacture of mirtazapine

Publications (1)

Publication Number Publication Date
NO20070776L true NO20070776L (no) 2007-04-11

Family

ID=35509331

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070776A NO20070776L (no) 2004-07-22 2007-02-09 Forbedret prosess for fremstilling av mirtazapin

Country Status (17)

Country Link
US (1) US20080207896A1 (no)
EP (1) EP1768980B1 (no)
KR (1) KR20070053697A (no)
AR (1) AR050004A1 (no)
AT (1) ATE415401T1 (no)
AU (1) AU2005263761A1 (no)
BR (1) BRPI0513571A (no)
CA (1) CA2572831A1 (no)
DE (1) DE602005011294D1 (no)
DK (1) DK1768980T3 (no)
ES (2) ES2246161B1 (no)
IL (1) IL180345A0 (no)
MX (1) MX2007000725A (no)
NO (1) NO20070776L (no)
PT (1) PT1768980E (no)
RU (1) RU2007106721A (no)
WO (1) WO2006008302A2 (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101485418B1 (ko) * 2013-05-29 2015-01-26 주식회사 메디켐코리아 고순도 미르타자핀의 제조방법
HUE055000T2 (hu) 2015-02-27 2021-10-28 Dechra Ltd Étvágy stimulálása, tömegvesztés kézbentartása és anorexia kezelése kutyák és macskák esetében
JP6452575B2 (ja) * 2015-08-19 2019-01-16 株式会社トクヤマ ミルタザピンの製造方法
KR102540021B1 (ko) * 2020-12-02 2023-06-07 (주)유케이케미팜 대량 생산에 적합한 미르타자핀의 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2547319B1 (fr) * 1983-06-09 1987-10-09 Gleizes Raymond Procede et appareil de fabrication de couches monocristallines et macrocristallines, notamment pour cellules photovoltaiques
US6012983A (en) * 1996-12-30 2000-01-11 Walker Asset Management Limited Partnership Automated play gaming device
US6960133B1 (en) * 2000-08-28 2005-11-01 Igt Slot machine game having a plurality of ways for a user to obtain payouts based on selection of one or more symbols (power pays)
US6545149B2 (en) * 1999-04-19 2003-04-08 Teva Pharmaceutical Industries Ltd. Synthesis and crystallization of piperazine ring-containing compounds
AU781221B2 (en) * 1999-04-19 2005-05-12 Teva Pharmaceutical Industries Ltd. Novel synthesis and crystallization of piperazine ring-containing compounds
CN1356903A (zh) * 1999-04-19 2002-07-03 特瓦制药工业有限公司 含哌嗪环化合物的新型合成和结晶方法

Also Published As

Publication number Publication date
IL180345A0 (en) 2007-06-03
EP1768980B1 (en) 2008-11-26
PT1768980E (pt) 2009-03-02
KR20070053697A (ko) 2007-05-25
AU2005263761A1 (en) 2006-01-26
ATE415401T1 (de) 2008-12-15
EP1768980A2 (en) 2007-04-04
WO2006008302A2 (en) 2006-01-26
RU2007106721A (ru) 2008-08-27
CA2572831A1 (en) 2006-01-26
ES2246161A1 (es) 2006-02-01
DK1768980T3 (da) 2009-03-16
DE602005011294D1 (de) 2009-01-08
WO2006008302A3 (en) 2006-04-13
US20080207896A1 (en) 2008-08-28
ES2246161B1 (es) 2007-04-01
ES2318520T3 (es) 2009-05-01
AR050004A1 (es) 2006-09-20
BRPI0513571A (pt) 2008-05-06
MX2007000725A (es) 2007-05-23

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application