NO20071012L - Fremgangsmate for fremstilling av D-erytro-2,2-difluor-2-deoksy-1-oksoribosederivat - Google Patents

Fremgangsmate for fremstilling av D-erytro-2,2-difluor-2-deoksy-1-oksoribosederivat

Info

Publication number
NO20071012L
NO20071012L NO20071012A NO20071012A NO20071012L NO 20071012 L NO20071012 L NO 20071012L NO 20071012 A NO20071012 A NO 20071012A NO 20071012 A NO20071012 A NO 20071012A NO 20071012 L NO20071012 L NO 20071012L
Authority
NO
Norway
Prior art keywords
erythro
deoxy
difluoro
preparation
derivative
Prior art date
Application number
NO20071012A
Other languages
English (en)
Inventor
Young-Kil Chang
Gwan Sun Lee
Jaeheon Lee
Gha-Seung Park
Moonsub Lee
Cheol-Kyong Kim
Jae-Chul Lee
Original Assignee
Hanmi Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharm Ind Co Ltd filed Critical Hanmi Pharm Ind Co Ltd
Publication of NO20071012L publication Critical patent/NO20071012L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/08—Deoxysugars; Unsaturated sugars; Osones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Furan Compounds (AREA)

Abstract

3R-karboksylatenantiomer-derivat av formel (III) kan fremstilles lett og selektivt ved fremgangsmåten ifølge foreliggende oppfinnelse, og et høy-rent D-erytro-2,2-difluor-2-deoksy-1 -oksoribose-derivat kan fremstilles effektivt fra forbindelsen av formel (III) som et mellomprodukt.
NO20071012A 2004-07-23 2007-02-22 Fremgangsmate for fremstilling av D-erytro-2,2-difluor-2-deoksy-1-oksoribosederivat NO20071012L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020040057711A KR100578616B1 (ko) 2004-07-23 2004-07-23 Ｄ-에리트로-2,2-다이플루오로-2-데옥시-1-옥소라이보스화합물의 제조방법
PCT/KR2005/001955 WO2006009353A1 (en) 2004-07-23 2005-06-23 Method for the preparation of d-erythro-2,2-difluoro-2-deoxy-1-oxoribose derivative

Publications (1)

Publication Number Publication Date
NO20071012L true NO20071012L (no) 2007-02-22

Family

ID=35785434

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071012A NO20071012L (no) 2004-07-23 2007-02-22 Fremgangsmate for fremstilling av D-erytro-2,2-difluor-2-deoksy-1-oksoribosederivat

Country Status (15)

Country Link
US (1) US7638642B2 (no)
EP (1) EP1781677B1 (no)
JP (1) JP4674297B2 (no)
KR (1) KR100578616B1 (no)
CN (1) CN1989147B (no)
AU (1) AU2005264678B2 (no)
BR (1) BRPI0513712A (no)
CA (1) CA2574401C (no)
ES (1) ES2431631T3 (no)
HK (1) HK1101587A1 (no)
IL (1) IL180893A (no)
MX (1) MX2007000914A (no)
NO (1) NO20071012L (no)
RU (1) RU2337917C1 (no)
WO (1) WO2006009353A1 (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070249823A1 (en) * 2006-04-20 2007-10-25 Chemagis Ltd. Process for preparing gemcitabine and associated intermediates
KR100741310B1 (ko) * 2006-08-01 2007-08-01 (주) 유일팜테크 젬시타빈의 합성에 유용한 신규한나프탈렌-2-카르복실레이트 유도체와 그의 제조방법
KR101357409B1 (ko) * 2006-11-03 2014-02-03 에스티팜 주식회사 2′-데옥시-2′,2′-디플루오로시티딘의 제조방법
KR100858842B1 (ko) * 2007-03-23 2008-09-22 동우신테크 주식회사 키랄아민을 이용한 광학활성 옥소라이보스유도체의제조방법
US7994310B2 (en) 2007-03-23 2011-08-09 Dongwoo Syntech Co., Ltd. Process for preparing 2′-deoxy-2′, 2′-difluorocytidine
KR100863463B1 (ko) * 2007-03-23 2008-10-16 동우신테크 주식회사 광학적으로 순수한 옥소라이보스유도체의 제조방법
CN100475832C (zh) * 2007-05-31 2009-04-08 南京卡文迪许生物工程技术有限公司 一种新颖的高立体选择性合成吉西他滨工艺及中间体
CN102153601A (zh) * 2011-02-26 2011-08-17 湖南欧亚生物有限公司 一种高选择性的制备盐酸吉西他滨以及其中间体的方法
CN103232508A (zh) * 2012-05-22 2013-08-07 湖北一半天制药有限公司 工业化盐酸吉西他滨的合成方法
US10894781B2 (en) * 2016-06-30 2021-01-19 Hindustan Petroleum Corporation Ltd. Mannitol based gelators for oil spillage applications
CN113461657B (zh) * 2021-08-17 2022-05-17 天津大学 一种有机小分子凝胶剂及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES416865A1 (es) * 1972-07-13 1976-03-01 Pfizer Procedimiento para preparar w-pentanorprostaglandinas sus- tituidas en la posicion 15.
US4526988A (en) 1983-03-10 1985-07-02 Eli Lilly And Company Difluoro antivirals and intermediate therefor
US5223608A (en) 1987-08-28 1993-06-29 Eli Lilly And Company Process for and intermediates of 2',2'-difluoronucleosides
US4965374A (en) 1987-08-28 1990-10-23 Eli Lilly And Company Process for and intermediates of 2',2'-difluoronucleosides
ATE179713T1 (de) * 1987-08-28 1999-05-15 Lilly Co Eli Verfahren zur selektiven isolierung von beta-2'- desoxy-2'2'-difluorocytidin oder seiner salze
US5401861A (en) * 1992-06-22 1995-03-28 Eli Lilly And Company Low temperature process for preparing alpha-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl sulfonates
ATE153669T1 (de) * 1992-06-22 1997-06-15 Lilly Co Eli Verfahren zur herstellung von mit alpha-anomeren angereicherten 1-halogen-2-deoxy-2,2-difluor-d- ribofuranosyl-derivaten
CA2136788C (en) 1993-11-30 2005-01-25 Thomas Charles Britton Process for preparing 2,2-difluoroketene silyl acetals and .alpha.,.alpha.-difluoro-.beta.-silyloxy-1,3-dioxolane-4-propanoic acid esters
US5428176A (en) * 1994-04-14 1995-06-27 Eli Lilly And Company Process for preparing 2,2-difluoroketene silyl O,S-acetals and α,α-difluoro-β-silyloxy-1,3-dioxolane-4-propanoic acid O,S-esters

Also Published As

Publication number Publication date
MX2007000914A (es) 2007-04-13
CN1989147A (zh) 2007-06-27
HK1101587A1 (en) 2007-10-18
WO2006009353A1 (en) 2006-01-26
EP1781677A1 (en) 2007-05-09
RU2337917C1 (ru) 2008-11-10
IL180893A (en) 2010-12-30
US20080058509A1 (en) 2008-03-06
RU2007106848A (ru) 2008-09-10
EP1781677A4 (en) 2012-05-02
KR20060008056A (ko) 2006-01-26
CN1989147B (zh) 2010-05-12
CA2574401C (en) 2011-03-29
BRPI0513712A (pt) 2008-05-13
CA2574401A1 (en) 2006-01-26
JP2008507506A (ja) 2008-03-13
JP4674297B2 (ja) 2011-04-20
US7638642B2 (en) 2009-12-29
ES2431631T3 (es) 2013-11-27
AU2005264678B2 (en) 2008-06-12
EP1781677B1 (en) 2013-08-07
KR100578616B1 (ko) 2006-05-10
AU2005264678A1 (en) 2006-01-26
IL180893A0 (en) 2007-07-04

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