NO20071707L - Fremstilling av 4,5-dihydro-pyrazolo[3,4-C]Pyrid-2-oner - Google Patents

Fremstilling av 4,5-dihydro-pyrazolo[3,4-C]Pyrid-2-oner

Info

Publication number
NO20071707L
NO20071707L NO20071707A NO20071707A NO20071707L NO 20071707 L NO20071707 L NO 20071707L NO 20071707 A NO20071707 A NO 20071707A NO 20071707 A NO20071707 A NO 20071707A NO 20071707 L NO20071707 L NO 20071707L
Authority
NO
Norway
Prior art keywords
pyrid
pyrazolo
dihydro
preparation
phenylhydrazines
Prior art date
Application number
NO20071707A
Other languages
English (en)
Inventor
Bang-Chi Chen
Rulin Zhao
Huiping Zhang
Bei Wang
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO20071707L publication Critical patent/NO20071707L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

Det beskrives en ny fremgangsmåte, og mellomprodukter derav, for fremstilling av 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-oner representert ved formel (I), så vel som de tilsvarende pyrazoler, fra passende fenylhydraziner. (I) Disse forbindelser kan være anvendelige som faktor Xa-hemmere. ?? ?? ?? ?? 1
NO20071707A 2004-09-28 2007-03-30 Fremstilling av 4,5-dihydro-pyrazolo[3,4-C]Pyrid-2-oner NO20071707L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61394304P 2004-09-28 2004-09-28
US11/234,942 US20060069085A1 (en) 2004-09-28 2005-09-26 Preparation of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones
PCT/US2005/034551 WO2006135425A2 (en) 2004-09-28 2005-09-27 Preparation of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones

Publications (1)

Publication Number Publication Date
NO20071707L true NO20071707L (no) 2007-05-25

Family

ID=36100089

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071707A NO20071707L (no) 2004-09-28 2007-03-30 Fremstilling av 4,5-dihydro-pyrazolo[3,4-C]Pyrid-2-oner

Country Status (5)

Country Link
US (1) US20060069085A1 (no)
EP (1) EP1805179A2 (no)
JP (1) JP2008514713A (no)
NO (1) NO20071707L (no)
WO (1) WO2006135425A2 (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI331526B (en) * 2001-09-21 2010-10-11 Bristol Myers Squibb Pharma Co Lactam-containing compounds and derivatives thereof as factor xa inhibitors
TW200738672A (en) * 2001-12-10 2007-10-16 Bristol Myers Squibb Co Intermediated for the preparation of 4,5-dihydro-pyrazolo [3,4-c] pyrid-2-ones
US7304157B2 (en) * 2004-09-28 2007-12-04 Bristol-Myers Squibb Company Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones
US20070203178A1 (en) * 2004-09-28 2007-08-30 Malley Mary F Crystalline solvates of apixaban
TW200634011A (en) * 2004-12-15 2006-10-01 Bristol Myers Squibb Co Crystalline forms of a factor xa inhibitor
RU2012101214A (ru) 2009-06-16 2013-07-27 Пфайзер Инк. Лекарственные формы апиксабана
US8440693B2 (en) 2009-12-22 2013-05-14 Novartis Ag Substituted isoquinolinones and quinazolinones
US8969341B2 (en) 2011-11-29 2015-03-03 Novartis Ag Pyrazolopyrrolidine compounds
UY34591A (es) 2012-01-26 2013-09-02 Novartis Ag Compuestos de imidazopirrolidinona
US9365576B2 (en) 2012-05-24 2016-06-14 Novartis Ag Pyrrolopyrrolidinone compounds
WO2014115077A1 (en) 2013-01-22 2014-07-31 Novartis Ag Substituted purinone compounds
US9556180B2 (en) 2013-01-22 2017-01-31 Novartis Ag Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the P53/MDM2 interaction
US8975417B2 (en) 2013-05-27 2015-03-10 Novartis Ag Pyrazolopyrrolidine derivatives and their use in the treatment of disease
MX2015016344A (es) 2013-05-27 2016-03-01 Novartis Ag Derivados de imidazo-pirrolidinona y su uso en el tratamiento de enfermedades.
PL3004112T3 (pl) 2013-05-28 2018-02-28 Novartis Ag Pochodne pirazolo-pirolidyn-4-onu oraz ich zastosowanie w leczeniu choroby
MX2015016421A (es) 2013-05-28 2016-03-03 Novartis Ag Derivados de pirazolo-pirrolidin-4-ona como inhibidores de bet y su uso en el tratamiento de enfermedades.
EP3071571A1 (en) 2013-11-21 2016-09-28 Novartis AG Pyrrolopyrrolone derivatives and their use as bet inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1140941T3 (da) * 1998-12-23 2005-02-14 Bristol Myers Squibb Pharma Co Nitrogenholdige heterobicykliske forbindelser som faktor Xa-inhibitorer
TWI331526B (en) * 2001-09-21 2010-10-11 Bristol Myers Squibb Pharma Co Lactam-containing compounds and derivatives thereof as factor xa inhibitors
CA2726702A1 (en) * 2001-09-21 2003-04-03 Bristol-Myers Squibb Company Lactam-containing compounds and derivatives thereof as factor xa inhibitors
TW200302225A (en) * 2001-12-04 2003-08-01 Bristol Myers Squibb Co Substituted amino methyl factor Xa inhibitors
TW200738672A (en) * 2001-12-10 2007-10-16 Bristol Myers Squibb Co Intermediated for the preparation of 4,5-dihydro-pyrazolo [3,4-c] pyrid-2-ones
US7304157B2 (en) * 2004-09-28 2007-12-04 Bristol-Myers Squibb Company Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones
US7396932B2 (en) * 2004-09-28 2008-07-08 Bristol-Myers Squibb Company Process for preparing 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones

Also Published As

Publication number Publication date
US20060069085A1 (en) 2006-03-30
JP2008514713A (ja) 2008-05-08
WO2006135425A2 (en) 2006-12-21
EP1805179A2 (en) 2007-07-11
WO2006135425A3 (en) 2007-02-22

Similar Documents

Publication Publication Date Title
NO20071707L (no) Fremstilling av 4,5-dihydro-pyrazolo[3,4-C]Pyrid-2-oner
NO20071702L (no) Fremgangsmate for fremstilling av 4,5-dihydro-pyrazolo[3,4-C]pyrid-oner
WO2004037811A8 (de) Ausgewählte cgrp-antagonisten, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
WO2005103037A3 (de) Ausgewählte cgrp-antagonisten, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
WO2006128852A3 (en) Heterocyclic spiro-compounds as aldosterone synthase inhibitors
WO2006103277A3 (en) 2 , 4 , 5-substituted piperidines as renin inhibitors
WO2009146218A3 (en) Compounds including an anti-inflammatory pharmacore and methods of use
TW200500339A (en) Pyrrolidine derivatives, and process for the preparation
AU2003258045A1 (en) Novel gamma-lactams as beta-secretase inhibitors
WO2005032472A3 (en) Pyrrolidine and piperidine derivatives as factor xa inhibitors
NO20071634L (no) Effektiv syntese av 4,5-dihydro-pyrazolo(3,4-C)pyrid-2-oner
WO2005105096A3 (en) Fused heterocyclic compounds
WO2007002308A3 (en) Process for preparing triazole substituted azaindoleoxoacetic piperazine derivatives and novel salt forms produced therein
NO20072753L (no) 3-Etylidenhydrazinosubstituerte heterocykliske forbindelser som trombopoietinreseptoraktivatorer
NO20064351L (no) Caspaseinhibitorer og anvendelser derav
WO2007062308A3 (en) Homo- and heterocyclic compounds suitable as cetp inhibitors
WO2004099197A3 (de) Substituierte oxyarene und deren verwendung zur bekämpfung von schädlingen
WO2006079720A8 (fr) Nouveaux derives d1oximes heterocycliques, leur procede de preparation et leur utilisation comme agents hypoglycemiants et hypoli pemiants
WO2004067703A3 (en) 5ht7 antagonists and inverse agonists
IL173582A0 (en) A process for the preparation of phenyltetrazole derivatives
WO2003080631A8 (en) Plasma carboxypeptidase b inhibitors
SG149005A1 (en) Process for the preparation of thiazolopyrimidines
TW200510323A (en) Process for the preparation of nonpeptide substituted spirobenzoazepine derivatives
WO2006036498A3 (en) A process for the preparation of 1,3,5-trisubstituted pyrazoles via [3+2] cycloaddition
DE60323748D1 (de) 1,3-diaza-dibenzoazulene als inhibitoren der produfür deren herstellung

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application