NO20061126L - Aminopyroner og deres anvendelse som ATM-inhibitorer - Google Patents
Aminopyroner og deres anvendelse som ATM-inhibitorerInfo
- Publication number
- NO20061126L NO20061126L NO20061126A NO20061126A NO20061126L NO 20061126 L NO20061126 L NO 20061126L NO 20061126 A NO20061126 A NO 20061126A NO 20061126 A NO20061126 A NO 20061126A NO 20061126 L NO20061126 L NO 20061126L
- Authority
- NO
- Norway
- Prior art keywords
- aminopyrones
- compounds
- atm
- inhibitors
- atm inhibitors
- Prior art date
Links
- AJJKPRWJTNUWLU-UHFFFAOYSA-N 3-aminopyran-2-one Chemical class NC1=CC=COC1=O AJJKPRWJTNUWLU-UHFFFAOYSA-N 0.000 title 1
- 239000012827 ATM inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 102000000872 ATM Human genes 0.000 abstract 1
- 101000785063 Homo sapiens Serine-protein kinase ATM Proteins 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- AIDS & HIV (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49477603P | 2003-08-13 | 2003-08-13 | |
| PCT/GB2004/003507 WO2005016919A1 (en) | 2003-08-13 | 2004-08-13 | Aminopyrones and their use as atm inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20061126L true NO20061126L (no) | 2006-05-09 |
Family
ID=34193236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20061126A NO20061126L (no) | 2003-08-13 | 2006-03-08 | Aminopyroner og deres anvendelse som ATM-inhibitorer |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US7429660B2 (de) |
| EP (1) | EP1654257B1 (de) |
| JP (1) | JP2007501836A (de) |
| KR (1) | KR20060066722A (de) |
| CN (1) | CN1867566B (de) |
| AT (1) | ATE461193T1 (de) |
| AU (1) | AU2004265149A1 (de) |
| BR (1) | BRPI0413467A (de) |
| CA (1) | CA2534300A1 (de) |
| DE (1) | DE602004026071D1 (de) |
| ES (1) | ES2341342T3 (de) |
| GB (1) | GB2420781B (de) |
| HK (1) | HK1097273A1 (de) |
| MX (1) | MXPA06001599A (de) |
| NO (1) | NO20061126L (de) |
| NZ (1) | NZ545919A (de) |
| TW (1) | TW200524924A (de) |
| WO (1) | WO2005016919A1 (de) |
| ZA (1) | ZA200601595B (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0119865D0 (en) * | 2001-08-14 | 2001-10-10 | Cancer Res Campaign Tech | DNA-PK inhibitors |
| NZ545919A (en) * | 2003-08-13 | 2009-07-31 | Kudos Pharm Ltd | Aminopyrones and their use as ATM inhibitors |
| AU2005286329A1 (en) * | 2004-09-20 | 2006-03-30 | Cancer Research Technology Limited | DNA-PK inhibitors |
| EP1848712A1 (de) * | 2005-02-09 | 2007-10-31 | Kudos Pharmaceuticals Ltd | Atm-inhibitoren |
| AR054438A1 (es) * | 2005-04-15 | 2007-06-27 | Kudos Pharm Ltd | Inhibidores de adn -pk |
| TW200745094A (en) * | 2005-08-31 | 2007-12-16 | Kudos Pharm Ltd | ATM inhibitor |
| WO2007075655A2 (en) | 2005-12-19 | 2007-07-05 | Northwestern University | Compositions and methods for altering rnai |
| US20080279866A1 (en) * | 2006-08-25 | 2008-11-13 | The Brigham And Women's Hospital, Inc. | Induction of immunosuppression by inhibition of ATM |
| EP2117575A4 (de) | 2007-01-03 | 2013-06-05 | Burnham Inst Medical Research | Verfahren und zusammensetzungen in verbindung mit gerinnselbindenden verbindungen |
| WO2008080398A1 (en) * | 2007-01-05 | 2008-07-10 | Bkg Pharma Aps | Anti - infective agents such as phenothiazine and thioxanthene derivates to treat infectious diseases |
| UY31232A1 (es) * | 2007-07-19 | 2009-03-02 | Compuestos derivados de dibenzotifenilamino-cromen-4-onas activas sustituidas y sus isomeros y aplicaciones | |
| US8912136B2 (en) | 2009-12-18 | 2014-12-16 | Sanford-Burnham Medical Research Institute | Methods and compositions related to clot-binding compounds |
| AU2012275841A1 (en) | 2011-06-27 | 2014-01-16 | The Jackson Laboratory | Methods and compositions for treatment of cancer and autoimmune disease |
| EP2758403B1 (de) | 2011-09-21 | 2016-04-27 | Inception Orion, Inc. | Tricyclische verbindungen als neurogene wirkstoffe und neuroprotektiva |
| WO2015030057A1 (ja) | 2013-08-29 | 2015-03-05 | 富士フイルム株式会社 | 新規なモルホリン誘導体またはその塩 |
| KR20160049435A (ko) | 2014-10-27 | 2016-05-09 | 삼성전자주식회사 | Atm 저해제를 포함하는 세포의 노화를 감소시키기 위한 조성물 및 그의 용도 |
| CN110312717B (zh) * | 2017-02-27 | 2022-04-12 | 上海瑛派药业有限公司 | 取代的稠合杂芳三环化合物作为激酶抑制剂及其应用 |
| CN109045042A (zh) * | 2018-09-21 | 2018-12-21 | 上海交通大学医学院附属上海儿童医学中心 | Atm抑制剂在制备抑制急性淋巴细胞性白血病复发的药物中的应用 |
| US20200355997A1 (en) * | 2019-05-08 | 2020-11-12 | Facebook Technologies, Llc | Thianthrene derivatized monomers and polymers for volume bragg gratings |
| US11718580B2 (en) | 2019-05-08 | 2023-08-08 | Meta Platforms Technologies, Llc | Fluorene derivatized monomers and polymers for volume Bragg gratings |
| US11780819B2 (en) | 2019-11-27 | 2023-10-10 | Meta Platforms Technologies, Llc | Aromatic substituted alkane-core monomers and polymers thereof for volume Bragg gratings |
| JP2023539715A (ja) | 2020-06-24 | 2023-09-19 | アストラゼネカ ユーケー リミテッド | 抗体－薬物コンジュゲートとａｔｍ阻害剤との組合わせ |
| US11879024B1 (en) | 2020-07-14 | 2024-01-23 | Meta Platforms Technologies, Llc | Soft mold formulations for surface relief grating fabrication with imprinting lithography |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1303724A (de) | 1969-05-14 | 1973-01-17 | ||
| JPH0753725B2 (ja) * | 1987-10-08 | 1995-06-07 | 富山化学工業株式会社 | ４ｈ―１―ベンゾピラン―４―オン誘導体およびその塩、それらの製造法並びにそれらを含有する抗炎症剤 |
| US5284856A (en) * | 1988-10-28 | 1994-02-08 | Hoechst Aktiengesellschaft | Oncogene-encoded kinases inhibition using 4-H-1-benzopyran-4-one derivatives |
| WO1990006921A1 (en) | 1988-12-21 | 1990-06-28 | The Upjohn Company | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones |
| US5703075A (en) * | 1988-12-21 | 1997-12-30 | Pharmacia & Upjohn Company | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones |
| JPH03215423A (ja) | 1990-01-18 | 1991-09-20 | Kyowa Hakko Kogyo Co Ltd | 血管拡張剤 |
| JPH05509302A (ja) | 1990-06-20 | 1993-12-22 | ジ・アップジョン・カンパニー | 抗アテローム性動脈硬化性および抗血栓性１―ベンゾピラン―４―オン類および２―アミノ―１，３―ベンゾオキサジン―４―オン類 |
| US5252735A (en) * | 1990-06-29 | 1993-10-12 | The Upjohn Company | Antiatherosclerotic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones |
| US5302613A (en) * | 1990-06-29 | 1994-04-12 | The Upjohn Company | Antiatheroscleroic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones |
| DK0489877T3 (da) * | 1990-06-29 | 1996-02-05 | Upjohn Co | Antiatherosklerotiske og antithrombotiske 2-amino-6-phenyl-4H-pyran-4-oner |
| WO1994005283A1 (en) | 1992-09-02 | 1994-03-17 | Kyowa Hakko Kogyo Co., Ltd. | Anti-hiv drug |
| DE69427907T2 (de) * | 1993-04-09 | 2002-04-04 | Toyama Chemical Co Ltd | Immunomodulator, zelladhäsionsinhibitor und mittel zur behandlung und vorbeugung von autoimmunerkrankungen |
| US5378725A (en) | 1993-07-19 | 1995-01-03 | The Arizona Board Of Regents | Inhibition of phosphatidylinositol 3-kinase with wortmannin and analogs thereof |
| US5468773A (en) | 1993-08-25 | 1995-11-21 | Eli Lilly And Company | Methods for inhibiting bone loss and cartilage degradation using wortmannin and its analogs |
| US5441947A (en) | 1993-08-25 | 1995-08-15 | Eli Lilly And Company | Methods of inhibiting vascular restenosis |
| US5504103A (en) | 1993-08-25 | 1996-04-02 | Eli Lilly And Company | Inhibition of phosphatidylinositol 3-kinase with 17 β-hydroxywortmannin and analogs thereof |
| CA2133815A1 (en) | 1993-10-12 | 1995-04-13 | Jeffrey Alan Dodge | Inhibition of phosphatidylinositol 3-kinase with viridin, demethoxyviridin, viridiol, demethoxyviridiol, virone, wortmannolone, and analogs thereof |
| US6632789B1 (en) | 1994-04-29 | 2003-10-14 | The United States Of America As Represented By The Secretary Of The Navy | Methods for modulating T cell responses by manipulating intracellular signal transduction |
| US5480906A (en) | 1994-07-01 | 1996-01-02 | Eli Lilly And Company | Stereochemical Wortmannin derivatives |
| GB9521987D0 (en) | 1995-10-26 | 1996-01-03 | Ludwig Inst Cancer Res | Phosphoinositide 3-kinase modulators |
| US5733920A (en) * | 1995-10-31 | 1998-03-31 | Mitotix, Inc. | Inhibitors of cyclin dependent kinases |
| WO1997018323A2 (en) | 1995-11-16 | 1997-05-22 | Icos Corporation | Cell-cycle checkpoint phosphatidylinositol- (pik-) related kinases, genes coding therefor and methods for assaying and modulating enzymatic activity |
| GB2302021A (en) | 1996-10-16 | 1997-01-08 | Lilly Co Eli | Inhibiting bone loss or resorption |
| AU7953598A (en) | 1997-06-06 | 1998-12-21 | Mayo Foundation For Medical Education And Research | Screening for phosphatidylinositol related-kinase inhibitors |
| AU8068198A (en) | 1997-06-13 | 1998-12-30 | President And Fellows Of Harvard College | Methods for treating human cancers |
| FR2776291B1 (fr) | 1998-03-18 | 2000-06-16 | Pf Medicament | Nouveaux derives bis-benzamides, leur procede de fabrication, les compositions pharmaceutiques les contenant et leur utilisation comme medicament |
| US6348311B1 (en) * | 1999-02-10 | 2002-02-19 | St. Jude Childre's Research Hospital | ATM kinase modulation for screening and therapies |
| US6387640B1 (en) * | 1999-02-10 | 2002-05-14 | St. Jude Children's Research Hospital | ATM kinase modulation for screening and therapies |
| US6333180B1 (en) * | 1999-12-21 | 2001-12-25 | International Flavors & Fragrances Inc. | Bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate |
| WO2001053266A1 (en) | 2000-01-24 | 2001-07-26 | Kinacia Pty Ltd. | Therapeutic morpholino-substituted compounds |
| CN1245974C (zh) * | 2000-06-28 | 2006-03-22 | 特瓦制药工业有限公司 | 卡维地洛 |
| US7179912B2 (en) | 2000-09-01 | 2007-02-20 | Icos Corporation | Materials and methods to potentiate cancer treatment |
| EP1353693B1 (de) | 2001-01-16 | 2005-03-16 | Glaxo Group Limited | Pharmazeutische mischung gegen krebs, die ein 4-chinazolinamin in kombination mit paclitaxel, carboplatin or vinorelbine enthält |
| GB0119865D0 (en) * | 2001-08-14 | 2001-10-10 | Cancer Res Campaign Tech | DNA-PK inhibitors |
| GB0119863D0 (en) * | 2001-08-14 | 2001-10-10 | Cancer Res Campaign Tech | DNA-PK inhibitors |
| AU2002349912A1 (en) | 2001-10-24 | 2003-05-06 | Iconix Pharmaceuticals, Inc. | Modulators of phosphoinositide 3-kinase |
| AU2002357667A1 (en) | 2001-10-24 | 2003-05-06 | Iconix Pharmaceuticals, Inc. | Modulators of phosphoinositide 3-kinase |
| US7049313B2 (en) * | 2002-02-25 | 2006-05-23 | Kudos Pharmaceuticals Ltd. | ATM inhibitors |
| SI1485377T1 (sl) * | 2002-02-25 | 2010-04-30 | Kudos Pharm Ltd | Piranoni, uporabni kot inhibitorji ATM |
| US7196085B2 (en) * | 2002-04-30 | 2007-03-27 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
| NZ545919A (en) * | 2003-08-13 | 2009-07-31 | Kudos Pharm Ltd | Aminopyrones and their use as ATM inhibitors |
| AU2005286329A1 (en) * | 2004-09-20 | 2006-03-30 | Cancer Research Technology Limited | DNA-PK inhibitors |
| EP1848712A1 (de) | 2005-02-09 | 2007-10-31 | Kudos Pharmaceuticals Ltd | Atm-inhibitoren |
| AR054438A1 (es) * | 2005-04-15 | 2007-06-27 | Kudos Pharm Ltd | Inhibidores de adn -pk |
| UY31232A1 (es) * | 2007-07-19 | 2009-03-02 | Compuestos derivados de dibenzotifenilamino-cromen-4-onas activas sustituidas y sus isomeros y aplicaciones |
-
2004
- 2004-08-13 NZ NZ545919A patent/NZ545919A/en unknown
- 2004-08-13 CA CA002534300A patent/CA2534300A1/en not_active Abandoned
- 2004-08-13 TW TW093124420A patent/TW200524924A/zh unknown
- 2004-08-13 CN CN2004800299408A patent/CN1867566B/zh not_active Expired - Fee Related
- 2004-08-13 BR BRPI0413467-2A patent/BRPI0413467A/pt not_active IP Right Cessation
- 2004-08-13 US US10/918,180 patent/US7429660B2/en not_active Expired - Fee Related
- 2004-08-13 EP EP04768070A patent/EP1654257B1/de active Active
- 2004-08-13 JP JP2006523057A patent/JP2007501836A/ja active Pending
- 2004-08-13 ES ES04768070T patent/ES2341342T3/es active Active
- 2004-08-13 KR KR1020067002998A patent/KR20060066722A/ko not_active Application Discontinuation
- 2004-08-13 DE DE602004026071T patent/DE602004026071D1/de active Active
- 2004-08-13 GB GB0604321A patent/GB2420781B/en not_active Expired - Fee Related
- 2004-08-13 AT AT04768070T patent/ATE461193T1/de not_active IP Right Cessation
- 2004-08-13 MX MXPA06001599A patent/MXPA06001599A/es active IP Right Grant
- 2004-08-13 AU AU2004265149A patent/AU2004265149A1/en not_active Abandoned
- 2004-08-13 WO PCT/GB2004/003507 patent/WO2005016919A1/en active Application Filing
-
2006
- 2006-02-23 ZA ZA200601595A patent/ZA200601595B/xx unknown
- 2006-03-08 NO NO20061126A patent/NO20061126L/no not_active Application Discontinuation
-
2007
- 2007-05-08 HK HK07104900.4A patent/HK1097273A1/xx not_active IP Right Cessation
-
2008
- 2008-09-19 US US12/233,736 patent/US20090043091A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004265149A1 (en) | 2005-02-24 |
| US7429660B2 (en) | 2008-09-30 |
| GB2420781B (en) | 2008-07-09 |
| ZA200601595B (en) | 2007-03-28 |
| BRPI0413467A (pt) | 2006-10-17 |
| EP1654257B1 (de) | 2010-03-17 |
| HK1097273A1 (en) | 2007-06-22 |
| JP2007501836A (ja) | 2007-02-01 |
| GB2420781A (en) | 2006-06-07 |
| ES2341342T3 (es) | 2010-06-18 |
| MXPA06001599A (es) | 2006-05-19 |
| TW200524924A (en) | 2005-08-01 |
| KR20060066722A (ko) | 2006-06-16 |
| CA2534300A1 (en) | 2005-02-24 |
| CN1867566B (zh) | 2010-06-16 |
| DE602004026071D1 (de) | 2010-04-29 |
| NZ545919A (en) | 2009-07-31 |
| EP1654257A1 (de) | 2006-05-10 |
| GB0604321D0 (en) | 2006-04-12 |
| CN1867566A (zh) | 2006-11-22 |
| ATE461193T1 (de) | 2010-04-15 |
| WO2005016919A1 (en) | 2005-02-24 |
| US20090043091A1 (en) | 2009-02-12 |
| US20050054657A1 (en) | 2005-03-10 |
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