NO20034364L - Sapogenin-derivater, deres syntese og anvendelse samt metoder basert pa deres anvendelse - Google Patents

Sapogenin-derivater, deres syntese og anvendelse samt metoder basert pa deres anvendelse

Info

Publication number
NO20034364L
NO20034364L NO20034364A NO20034364A NO20034364L NO 20034364 L NO20034364 L NO 20034364L NO 20034364 A NO20034364 A NO 20034364A NO 20034364 A NO20034364 A NO 20034364A NO 20034364 L NO20034364 L NO 20034364L
Authority
NO
Norway
Prior art keywords
synthesis
methods based
sapogenin derivatives
sapogenin
derivatives
Prior art date
Application number
NO20034364A
Other languages
English (en)
Norwegian (no)
Other versions
NO20034364D0 (no
Inventor
Zongqin Xia
Yaer Hu
Paul Barraclough
Jim Hanson
Phil Gunning
Daryl Rees
Original Assignee
Phytotech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phytotech Ltd filed Critical Phytotech Ltd
Publication of NO20034364D0 publication Critical patent/NO20034364D0/no
Publication of NO20034364L publication Critical patent/NO20034364L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)
NO20034364A 2001-03-28 2003-09-29 Sapogenin-derivater, deres syntese og anvendelse samt metoder basert pa deres anvendelse NO20034364L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0107822.9A GB0107822D0 (en) 2001-03-28 2001-03-28 Sapogenin derivatives their synthesis and use methods based upon their use
ARP020101170A AR033079A1 (es) 2001-03-28 2002-03-27 Derivados de sapogeninas, sintesis y uso, y metodos en base a su uso
PCT/GB2002/001578 WO2002079221A2 (en) 2001-03-28 2002-03-28 Sapogenin derivatives, their synthesis and use

Publications (2)

Publication Number Publication Date
NO20034364D0 NO20034364D0 (no) 2003-09-29
NO20034364L true NO20034364L (no) 2003-11-28

Family

ID=9911795

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20034364A NO20034364L (no) 2001-03-28 2003-09-29 Sapogenin-derivater, deres syntese og anvendelse samt metoder basert pa deres anvendelse

Country Status (24)

Country Link
US (1) US20040147495A1 (uk)
EP (1) EP1383787B1 (uk)
JP (1) JP2004525945A (uk)
KR (1) KR20040007479A (uk)
CN (1) CN1678325A (uk)
AR (2) AR033079A1 (uk)
AT (1) ATE416185T1 (uk)
AU (1) AU2002242894B2 (uk)
BR (1) BR0208533A (uk)
CA (1) CA2442150A1 (uk)
CZ (1) CZ20032620A3 (uk)
GB (1) GB0107822D0 (uk)
HR (1) HRP20030770A2 (uk)
IL (1) IL158115A0 (uk)
MX (1) MXPA03008800A (uk)
NO (1) NO20034364L (uk)
NZ (1) NZ529136A (uk)
PE (1) PE20021042A1 (uk)
PL (1) PL364825A1 (uk)
RU (1) RU2311423C2 (uk)
TR (2) TR200700134T1 (uk)
UA (1) UA78696C2 (uk)
WO (1) WO2002079221A2 (uk)
ZA (2) ZA200307478B (uk)

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NZ563183A (en) * 2002-03-27 2009-03-31 Phytopharm Plc Therapeutic methods and uses of sapogenins and their derivatives
MXPA04009321A (es) * 2002-03-27 2005-01-25 Phytopharm Plc Metodos y usos terapeuticos de sapogeninas y sus derivados.
PT1558627E (pt) * 2002-10-28 2010-05-06 Phytopharm Plc Reduçao estereoespecífica de sapogen-3-onas
GB0409567D0 (en) 2004-04-28 2004-06-02 Phytopharm Plc Chemical compounds
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GB0424528D0 (en) * 2004-11-05 2004-12-08 Phytopharm Plc Chemical compounds
AU2010207597A1 (en) 2009-01-24 2011-08-18 Phytopharm Plc Treatment of neurotrophic factor mediated disorders
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CA2805693A1 (en) 2010-07-20 2012-01-26 Phytopharm Plc Treatment of l-dopa, dopamine agonist and/or dopamine enhancer induced disorders
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CN104177469A (zh) * 2013-05-28 2014-12-03 江苏柯菲平医药有限公司 一种知母中菝葜皂苷元衍生物的制备方法
CN104324038B (zh) * 2013-07-24 2018-11-06 四川京华创生物科技有限公司 一种薯蓣皂苷元-3-位衍生物的用途
EP3157528B1 (en) 2014-06-18 2023-09-13 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
MA55097A (fr) 2015-07-06 2022-01-05 Sage Therapeutics Inc Oxystérols et leurs procédés d'utilisation
MA42409A (fr) 2015-07-06 2018-05-16 Sage Therapeutics Inc Oxystérols et leurs procédés d'utilisation
PE20180482A1 (es) 2015-07-06 2018-03-07 Sage Therapeutics Inc Oxiesteroles y metodos de uso de los mismos
LT3436022T (lt) 2016-04-01 2022-06-27 Sage Therapeutics, Inc. Oksisteroliai ir jų panaudojimo būdai
US10752653B2 (en) 2016-05-06 2020-08-25 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
RS62222B1 (sr) 2016-07-07 2021-09-30 Sage Therapeutics Inc 24-hidroksisteroli supstituisani na poziciji 11 za upotrebu u lečenju stanja povezanih sa nmda
MA46351A (fr) 2016-09-30 2021-06-02 Sage Therapeutics Inc Oxystérols substitués en c7 et procédés en tant que modulateurs nmda
EP3529256B1 (en) 2016-10-18 2023-08-09 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
ES2952106T3 (es) 2016-10-18 2023-10-27 Sage Therapeutics Inc Oxisteroles y procedimientos de utilización de los mismos
CN109053854B (zh) * 2018-09-29 2021-05-14 深圳清博汇能医药科技有限公司 基于知母菝契皂苷元结构的衍生物、药物组合物及其应用

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Also Published As

Publication number Publication date
ZA200407460B (en) 2009-09-30
PL364825A1 (en) 2004-12-27
PE20021042A1 (es) 2002-11-19
HRP20030770A2 (en) 2005-08-31
MXPA03008800A (es) 2004-10-15
AR040402A1 (es) 2005-04-06
CN1678325A (zh) 2005-10-05
BR0208533A (pt) 2004-04-20
AR033079A1 (es) 2003-12-03
EP1383787B1 (en) 2008-12-03
RU2003131883A (ru) 2005-05-10
CA2442150A1 (en) 2002-10-10
TR200301613T2 (tr) 2004-08-23
KR20040007479A (ko) 2004-01-24
AU2002242894B2 (en) 2008-08-21
UA78696C2 (en) 2007-04-25
US20040147495A1 (en) 2004-07-29
CZ20032620A3 (cs) 2004-04-14
ZA200307478B (en) 2009-04-29
EP1383787A2 (en) 2004-01-28
RU2311423C2 (ru) 2007-11-27
TR200700134T1 (tr) 2007-02-21
GB0107822D0 (en) 2001-05-23
NO20034364D0 (no) 2003-09-29
ATE416185T1 (de) 2008-12-15
NZ529136A (en) 2005-12-23
JP2004525945A (ja) 2004-08-26
WO2002079221A3 (en) 2003-04-17
IL158115A0 (en) 2004-03-28
WO2002079221A2 (en) 2002-10-10

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