DK1525193T3 - Acylaminothiazolderivater, deres fremstilling og deres terapeutiske anvendelse - Google Patents

Acylaminothiazolderivater, deres fremstilling og deres terapeutiske anvendelse

Info

Publication number
DK1525193T3
DK1525193T3 DK03750801T DK03750801T DK1525193T3 DK 1525193 T3 DK1525193 T3 DK 1525193T3 DK 03750801 T DK03750801 T DK 03750801T DK 03750801 T DK03750801 T DK 03750801T DK 1525193 T3 DK1525193 T3 DK 1525193T3
Authority
DK
Denmark
Prior art keywords
preparation
therapeutic use
acylaminothiazole derivatives
acylaminothiazole
derivatives
Prior art date
Application number
DK03750801T
Other languages
English (en)
Inventor
Sylvie Baltzer
Bruno Schoentjes
Dorsselaer Viviane Van
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Application granted granted Critical
Publication of DK1525193T3 publication Critical patent/DK1525193T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK03750801T 2002-07-17 2003-07-11 Acylaminothiazolderivater, deres fremstilling og deres terapeutiske anvendelse DK1525193T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0209061A FR2842523A1 (fr) 2002-07-17 2002-07-17 Derives d'acylaminothiazole, leur preparation et leur application en therapeutique
PCT/FR2003/002194 WO2004009565A2 (fr) 2002-07-17 2003-07-11 Derives d'acylaminothiazole, leur utilisation comme inhibiteurs de beta-amyloi

Publications (1)

Publication Number Publication Date
DK1525193T3 true DK1525193T3 (da) 2008-04-28

Family

ID=29797510

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03750801T DK1525193T3 (da) 2002-07-17 2003-07-11 Acylaminothiazolderivater, deres fremstilling og deres terapeutiske anvendelse

Country Status (14)

Country Link
US (2) US7291636B2 (da)
EP (1) EP1525193B1 (da)
JP (1) JP4680593B2 (da)
AR (1) AR040570A1 (da)
AT (1) ATE382040T1 (da)
AU (1) AU2003269018A1 (da)
CY (1) CY1107903T1 (da)
DE (1) DE60318317T2 (da)
DK (1) DK1525193T3 (da)
ES (1) ES2297198T3 (da)
FR (1) FR2842523A1 (da)
PT (1) PT1525193E (da)
TW (1) TWI313680B (da)
WO (1) WO2004009565A2 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2842523A1 (fr) * 2002-07-17 2004-01-23 Sanofi Synthelabo Derives d'acylaminothiazole, leur preparation et leur application en therapeutique
CN1688557A (zh) * 2002-10-09 2005-10-26 辉瑞产品公司 用于治疗神经变性疾病的噻唑化合物
HUE025659T2 (en) * 2003-12-26 2016-04-28 Kyowa Hakko Kirin Co Ltd Thiazole derivatives
RU2401262C2 (ru) * 2004-01-16 2010-10-10 Санофи-Авентис Производные алкиламинотиазола, их получение и их применение в терапии
FR2873370B1 (fr) * 2004-07-22 2006-10-20 Sanofi Synthelabo Derives d'acylaminothiazole, leur preparation et leur application en therapeutique
FR2865206B1 (fr) * 2004-01-16 2009-02-06 Sanofi Synthelabo Derives d'acylaminothiazole, leur preparation et leur application en therapeutique
WO2005073202A1 (fr) * 2004-01-16 2005-08-11 Sanofi-Aventis Derives d’acylaminothiazole et leur application comme inhibiteurs de beta-amyloide
US7384968B2 (en) 2004-04-01 2008-06-10 Pfizer Inc. Thiazole-amine compounds for the treatment of neurodegenerative disorders
US20050222227A1 (en) * 2004-04-01 2005-10-06 Pfizer Inc Oxazole-amine compounds for the treatment of neurodegenerative disorders
WO2006016219A2 (en) * 2004-08-03 2006-02-16 Chiesi Farmaceutici S.P.A. Derivatives of 1-phenylalkanecarboxylic acids for the treatment of neurodegenerative diseases
AU2007207743B2 (en) * 2006-01-18 2010-07-08 Amgen Inc. Thiazole compounds as protein kinase B (PKB) inhibitors
WO2007116901A1 (ja) * 2006-04-05 2007-10-18 Banyu Pharmaceutical Co., Ltd. 新規アリールアミド誘導体
CN100415709C (zh) 2006-05-15 2008-09-03 西北大学 β-(3,4-二羟基苯基)-α-羟基丙酸冰片酯、其合成方法和用途
DE102006048042A1 (de) * 2006-10-11 2008-04-17 Bayer Healthcare Ag Acylaminoimidazole und Acylaminothiazole
CA2692713A1 (en) 2007-07-17 2009-01-22 Amgen Inc. Heterocyclic modulators of pkb
WO2009011871A2 (en) * 2007-07-17 2009-01-22 Amgen Inc. Thiadiazole modulators of pkb
KR20110071004A (ko) * 2008-10-14 2011-06-27 액테리온 파마슈티칼 리미티드 페네틸아미드 유도체 및 이의 헤테로시클릭 유사체

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3796800A (en) * 1971-11-22 1974-03-12 Uniroyal Inc Anti-inflammatory triazole compositions and methods for using same
FR2546520B1 (fr) * 1983-05-27 1985-08-30 Sanofi Sa Nouveaux composes antibiotiques derives des cephalosporines
US5712270A (en) * 1995-11-06 1998-01-27 American Home Products Corporation 2-arylamidothiazole derivatives with CNS activity
HUP0000492A3 (en) * 1996-11-22 2000-06-28 Lilly Co Eli N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
FR2842523A1 (fr) * 2002-07-17 2004-01-23 Sanofi Synthelabo Derives d'acylaminothiazole, leur preparation et leur application en therapeutique
CN1688557A (zh) * 2002-10-09 2005-10-26 辉瑞产品公司 用于治疗神经变性疾病的噻唑化合物

Also Published As

Publication number Publication date
JP4680593B2 (ja) 2011-05-11
US20080051436A1 (en) 2008-02-28
US20050182104A1 (en) 2005-08-18
CY1107903T1 (el) 2013-09-04
JP2005538086A (ja) 2005-12-15
TWI313680B (en) 2009-08-21
TW200413341A (en) 2004-08-01
US7291636B2 (en) 2007-11-06
WO2004009565A3 (fr) 2004-04-08
AU2003269018A1 (en) 2004-02-09
DE60318317T2 (de) 2009-07-09
AR040570A1 (es) 2005-04-13
US7795289B2 (en) 2010-09-14
FR2842523A1 (fr) 2004-01-23
EP1525193B1 (fr) 2007-12-26
ES2297198T3 (es) 2008-05-01
ATE382040T1 (de) 2008-01-15
EP1525193A2 (fr) 2005-04-27
PT1525193E (pt) 2008-02-25
WO2004009565A2 (fr) 2004-01-29
DE60318317D1 (de) 2008-02-07

Similar Documents

Publication Publication Date Title
DK1419150T3 (da) 1-Phenylsulfonyl-1,3-dihydro-2H-indol-2-on-derivater, deres fremstilling og deres terapeutiske anvendelse
DK1578755T3 (da) Phosphonooxyguinalinderivater og deres farmaceutiske anvendelse
NO20030596L (no) Benzimidazolderivater, deres fremstilling og terapeutiske anvendelse
NO20035298D0 (no) CDK-inhiberende pyrimider, deres fremstilling og deres anvendelse som legemidler
DK1537096T3 (da) Derivater af dioxan-2-alkylcarbamater, fremstilling og terapeutisk anvendelse heraf
HK1076110A1 (en) Piperazinylacylpiperidine derivatives, their preparation and therapeutic use thereof
DK1161434T3 (da) Pyridopyranoazepinderivater, deres fremstilling og terapeutiske anvendelse
NO20051983D0 (no) 3-fenyl-substituert pyridoindolon, fremstilling derav og terapeutisk anvendelse derav.
DK1603915T3 (da) Substituerede 8-pyridinyl-dihydrospiro-cycloalkyl-pyrimido- 1,2-a-pyrimidin-6-on og 8-pyrimidinyl-dihydrospiro-cycloalkyl-pyrimido-1,2-a-pyrimidin-6-on-derivater og deres anvendelse mod neurogenerative sygdomme
NO20052124D0 (no) Nye 1,4-diazabisykloalkanderivater, deres fremstilling og anvendelse
DK1590321T3 (da) Arylalkylcarbamat-derivater, fremstilling og terapeutisk anvendelse deraf
DK1525193T3 (da) Acylaminothiazolderivater, deres fremstilling og deres terapeutiske anvendelse
DK1773829T3 (da) Aminotropanderivater, fremstilling og terapeutiske anvendelser heraf
NO20031838D0 (no) Benzokazinonderivater, deres fremstilling og anvendelse
NO20043349L (no) Kumarinderivater, fremgangsmate for deres framstilling og anvendelse derav
DK1417189T3 (da) Acylaminothiazolderivater, fremstilling og terapeutisk anvendelse heraf
NO20003773D0 (no) Syklobutenderivater, deres fremstilling og deres terapeutiske anvendelser
DK1387838T3 (da) Cyanoanthranylamid-derivater og deres anvendelse som lægemidler
DK1043307T3 (da) 3-amino-3-arylpropan-1-ol-derivater, deres fremstilling og anvendelse
IS2487B (is) Asýloxýpýrrólidín afleiður, framleiðsla og meðferðarnotkun þar á
DK1353912T3 (da) 2-Arylimino-2,3-dihydrothiazolderivater, fremgangsmåderne til deres fremstilling og deres terapeutiske anvendelse
DK1742947T3 (da) 6-substituerede pyridoindolanderivater, fremstilling og terapeutisk anvendelse heraf
NO20024107L (no) Tienopyridin derivater, deres fremstilling og anvendelse
NO20001782D0 (no) 3-amino-3-arylpropan-1-ol-derivater, deres fremstilling og anvendelse
NO20033965L (no) Caloporosidderivater, fremgangsmåte for deres fremstilling og deres anvendelse