NO20005839L - Preparater for behandling av HIV og andre virale infeksjoner - Google Patents

Preparater for behandling av HIV og andre virale infeksjoner

Info

Publication number
NO20005839L
NO20005839L NO20005839A NO20005839A NO20005839L NO 20005839 L NO20005839 L NO 20005839L NO 20005839 A NO20005839 A NO 20005839A NO 20005839 A NO20005839 A NO 20005839A NO 20005839 L NO20005839 L NO 20005839L
Authority
NO
Norway
Prior art keywords
hiv
virus
hydrogen
carbon atoms
prevent
Prior art date
Application number
NO20005839A
Other languages
English (en)
Other versions
NO20005839D0 (no
Inventor
James Berger Camden
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of NO20005839D0 publication Critical patent/NO20005839D0/no
Publication of NO20005839L publication Critical patent/NO20005839L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Farmasøytisk preparat som kan anvendes til å behandle virale infeksjoner, spesielt HIV. Preparatet omfatter fra omtrent 250 mg til omtrent 6000 mg av et benzimidazolderivat med formel I eller et farmasøytisk akseptabelt organisk eller uorganisk addisjonssalt derav, hvor X er hydrogen, halogen, alkyl med mindre enn 7 karbonatomer eller alkoksy med mindre enn 7 karbonatomer, n er et positivt helt tall mindre""enn'V,' " Y er hydrogen, klor, nitro, oksyklor, metyl eller etyl, R er hydrogen eller en alkylgruppe som har fra l til B karbon- atomer, og R2 er 4-tiazolyl. Den foretrukne forbindelse er tiabendazol. I den foreliggende oppfinnelse er det blitt funnet at forbindelsene beskrevet ovenfor er nyttige for inhibering av HIV og behandling av HIV-infeksjon ved anvendelse alene eller i en kombinasjon med andre anti-virale midler. Disse preparatene kan hindre replikasjon av HIV- viruset, hindre dannelse av virusstammer som er resistente mot behandling med benzimidazoler, hindre eller forsinke infeksjon av celler med HIV-virus og forsinke gjenopptreden av viruset i de behandlede cellene. Disse preparatene er også effektive mot hepatitt og viruser slik som herpes, influensa og rhinoviruser.
NO20005839A 1998-05-19 2000-11-17 Preparater for behandling av HIV og andre virale infeksjoner NO20005839L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8138498A 1998-05-19 1998-05-19
PCT/US1999/011059 WO1999059585A1 (en) 1998-05-19 1999-05-19 Compositions for the treatment of hiv and other viral infections

Publications (2)

Publication Number Publication Date
NO20005839D0 NO20005839D0 (no) 2000-11-17
NO20005839L true NO20005839L (no) 2001-01-16

Family

ID=22163807

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005839A NO20005839L (no) 1998-05-19 2000-11-17 Preparater for behandling av HIV og andre virale infeksjoner

Country Status (19)

Country Link
US (1) US6245789B1 (no)
EP (1) EP1079831A1 (no)
JP (1) JP2002515432A (no)
KR (1) KR20010043709A (no)
CN (1) CN1301158A (no)
AR (1) AR019305A1 (no)
AU (1) AU4004299A (no)
BR (1) BR9911043A (no)
CA (1) CA2329877A1 (no)
CO (1) CO5050303A1 (no)
HU (1) HUP0103319A2 (no)
ID (1) ID27457A (no)
IL (1) IL139002A0 (no)
NO (1) NO20005839L (no)
PE (1) PE20000550A1 (no)
PL (1) PL344223A1 (no)
SK (1) SK17442000A3 (no)
TR (1) TR200003383T2 (no)
WO (1) WO1999059585A1 (no)

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US6245789B1 (en) 1998-05-19 2001-06-12 The Procter & Gamble Company HIV and viral treatment
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US6608096B1 (en) * 2000-09-26 2003-08-19 University Of Arizona Foundation Compounds and methods for use thereof in the treatment of cancer or viral infections
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ATE274515T1 (de) 2001-03-08 2004-09-15 Smithkline Beecham Corp Pyrazolopyridinderivate
EP1372643A1 (en) 2001-03-30 2004-01-02 Smithkline Beecham Corporation Pyrazolopyridines, process for their preparation and use as therapeutic compounds
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ATE296826T1 (de) 2001-04-27 2005-06-15 Smithkline Beecham Corp Pyrazolo(1,5)pyridinderivate
PL366827A1 (en) * 2001-06-21 2005-02-07 Smithkline Beecham Corporation Imidazo[1,2-a]pyridine derivatives for the prophylaxis and treatment of herpes viral infections
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WO2004033454A1 (en) 2002-10-03 2004-04-22 Smithkline Beecham Corporation Therapeutic compounds based on pyrazolopyridine derivatives
AU2003900064A0 (en) * 2003-01-09 2003-01-23 Penam Investments Pty. Ltd. A method of treatment or prophylaxis of viral infection.
JP2005060362A (ja) * 2003-07-28 2005-03-10 Shionogi & Co Ltd セスキテルペン誘導体を含有する抗ＨＩＶ剤、抗ＢＶＤＶ剤、抗ＨＣＶ剤又は抗ＣｏＶ剤
EP2251010A1 (en) 2009-05-08 2010-11-17 Sygnis Bioscience GmbH & Co. KG Use of thiabendazole and derivatives thereof for the therapy of neurological conditions
US9655962B2 (en) * 2013-03-15 2017-05-23 Camas Incorporated Methods and compositions for reducing microorganisms in the oropharynx, nasopharynx and oral cavities
FR3057865A1 (fr) * 2016-10-21 2018-04-27 Laboratoire Michel Iderne Composition chimique
TW201936193A (zh) * 2017-12-05 2019-09-16 愛爾蘭商健生科學愛爾蘭無限公司 使用組合產品治療ｒｓｖ
KR102342313B1 (ko) * 2021-08-27 2021-12-24 (주)바이오메트릭스 테크놀로지 벤지미다졸-탄수화물 결합체 화합물을 포함하는 미셀, 이의 제조방법, 이의 항암제 또는 항바이러스제로서의 용도

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Also Published As

Publication number Publication date
PL344223A1 (en) 2001-10-08
JP2002515432A (ja) 2002-05-28
AU4004299A (en) 1999-12-06
AR019305A1 (es) 2002-02-13
US6245789B1 (en) 2001-06-12
SK17442000A3 (sk) 2001-08-06
CO5050303A1 (es) 2001-06-27
IL139002A0 (en) 2001-11-25
EP1079831A1 (en) 2001-03-07
CA2329877A1 (en) 1999-11-25
HUP0103319A2 (hu) 2002-05-29
WO1999059585A1 (en) 1999-11-25
BR9911043A (pt) 2001-02-13
NO20005839D0 (no) 2000-11-17
TR200003383T2 (tr) 2001-03-21
ID27457A (id) 2001-04-12
CN1301158A (zh) 2001-06-27
KR20010043709A (ko) 2001-05-25
PE20000550A1 (es) 2000-06-29

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