CO5160294A1 - Composicion farmaceutica que inhibe o detiene el crecimiento de virus en animales particularmente mamiferos sarrollo de virus en animales y composiciones farmaceuticas que los contienen - Google Patents
Composicion farmaceutica que inhibe o detiene el crecimiento de virus en animales particularmente mamiferos sarrollo de virus en animales y composiciones farmaceuticas que los contienenInfo
- Publication number
- CO5160294A1 CO5160294A1 CO00023489A CO00023489A CO5160294A1 CO 5160294 A1 CO5160294 A1 CO 5160294A1 CO 00023489 A CO00023489 A CO 00023489A CO 00023489 A CO00023489 A CO 00023489A CO 5160294 A1 CO5160294 A1 CO 5160294A1
- Authority
- CO
- Colombia
- Prior art keywords
- animals
- viruses
- inhibites
- viruss
- stops
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención revela un derivado de (5-aril-1,2,4-tiadiazol)-3-ilo-tiourea ó derivado de (5-aril-1,2,4-tiadiazol )-3-ilo urea de la fórmula:<EMI FILE="00023489_1" ID="1" IMF=JPEG >donde X es oxígeno o azufre, R es hidrógeno o alquilo que tiene desde 1 hasta 7 átomos de carbono, cloro, bromo o flúor, oxicloro, alcoxi que tiene la fórmula -O(CH2) y CH3 donde y es de desde 1 hasta 6 ó una sal de adición farmacéuticamente aceptable prodroga de ella.Igualmente, revela una composición farmacéuticamente que inhibe o retarda el desarrollo de virus en animales, particularmente mamíferos. La misma composición puede ser usada para tratar infecciones virales, particularmente hepatitis C, herpes simple, sarcoma de Kaposi y VIH. La composición preferiblemente contiene desde 10 mg hasta 6.000 mg.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28189699A | 1999-03-31 | 1999-03-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO5160294A1 true CO5160294A1 (es) | 2002-05-30 |
Family
ID=23079226
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO00023489A CO5160294A1 (es) | 1999-03-31 | 2000-03-31 | Composicion farmaceutica que inhibe o detiene el crecimiento de virus en animales particularmente mamiferos sarrollo de virus en animales y composiciones farmaceuticas que los contienen |
Country Status (11)
Country | Link |
---|---|
US (2) | US6258831B1 (es) |
EP (1) | EP1165070B1 (es) |
JP (1) | JP2002540156A (es) |
AR (1) | AR019505A1 (es) |
AT (1) | ATE297729T1 (es) |
AU (1) | AU763573B2 (es) |
CA (1) | CA2368615C (es) |
CO (1) | CO5160294A1 (es) |
DE (1) | DE60020820T2 (es) |
PE (1) | PE20001644A1 (es) |
WO (1) | WO2000057878A1 (es) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6423695B1 (en) * | 1998-01-13 | 2002-07-23 | Ribapharm, Inc. | Cytokine related treatments of disease |
US6245788B1 (en) * | 1999-03-31 | 2001-06-12 | The Procter & Gamble Company | Viral treatment |
DE10120627A1 (de) | 2001-04-26 | 2002-10-31 | Cmi Ag | Verwendung von Phyllanthusbestandteilen zur Behandlung oder Prophylaxe von Infekten durch Hepatitis B-Viren |
US20050239054A1 (en) * | 2002-04-26 | 2005-10-27 | Arimilli Murty N | Method and compositions for identifying anti-HIV therapeutic compounds |
PL211979B1 (pl) | 2002-04-26 | 2012-07-31 | Gilead Sciences | Pochodne fosfonianowe, ich zastosowanie w leczeniu zakażenia wirusem HIV i chorób wpływających na białe krwinki, oraz kompozycje farmaceutyczne zawierające te związki |
US20040010036A1 (en) * | 2002-05-07 | 2004-01-15 | Boris Rogovoy | N,N, -Substituted s-Aryl-Isothioureas, N,N,N, -Substituted s-Aryl-Isothioureas and combinatorial libraries thereof |
JP4733393B2 (ja) * | 2002-11-18 | 2011-07-27 | ポラリス・グループ | インビボでウイルス複製を阻害する方法 |
US20040175384A1 (en) * | 2003-12-12 | 2004-09-09 | Mohapatra Shyam S. | Protein kinase C as a target for the treatment of respiratory syncytial virus |
US7300924B2 (en) * | 2003-04-25 | 2007-11-27 | Gilead Sciences, Inc. | Anti-infective phosphonate analogs |
WO2005002626A2 (en) * | 2003-04-25 | 2005-01-13 | Gilead Sciences, Inc. | Therapeutic phosphonate compounds |
CN101410120A (zh) * | 2003-04-25 | 2009-04-15 | 吉里德科学公司 | 抗炎的膦酸酯化合物 |
WO2004096286A2 (en) | 2003-04-25 | 2004-11-11 | Gilead Sciences, Inc. | Antiviral phosphonate analogs |
US20050261237A1 (en) * | 2003-04-25 | 2005-11-24 | Boojamra Constantine G | Nucleoside phosphonate analogs |
US7427636B2 (en) | 2003-04-25 | 2008-09-23 | Gilead Sciences, Inc. | Inosine monophosphate dehydrogenase inhibitory phosphonate compounds |
US7452901B2 (en) * | 2003-04-25 | 2008-11-18 | Gilead Sciences, Inc. | Anti-cancer phosphonate analogs |
US7432261B2 (en) * | 2003-04-25 | 2008-10-07 | Gilead Sciences, Inc. | Anti-inflammatory phosphonate compounds |
US7407965B2 (en) | 2003-04-25 | 2008-08-05 | Gilead Sciences, Inc. | Phosphonate analogs for treating metabolic diseases |
US7470724B2 (en) | 2003-04-25 | 2008-12-30 | Gilead Sciences, Inc. | Phosphonate compounds having immuno-modulatory activity |
MXPA05011296A (es) | 2003-04-25 | 2006-01-24 | Gilead Sciences Inc | Conjugados de fosfonato inhibidores de la cinasa. |
US7432273B2 (en) | 2003-10-24 | 2008-10-07 | Gilead Sciences, Inc. | Phosphonate analogs of antimetabolites |
EP1678321A1 (en) | 2003-10-24 | 2006-07-12 | Gilead Sciences, Inc. | Methods and compositions for identifying therapeutic compounds |
US7427624B2 (en) | 2003-10-24 | 2008-09-23 | Gilead Sciences, Inc. | Purine nucleoside phosphorylase inhibitory phosphonate compounds |
US7253175B2 (en) * | 2003-11-13 | 2007-08-07 | Barnet Liberman | Method for treating athlete's foot |
US8592368B2 (en) | 2003-12-19 | 2013-11-26 | University Of South Florida | JAK/STAT inhibitors and MAPK/ERK inhibitors for RSV infection |
US20050153990A1 (en) * | 2003-12-22 | 2005-07-14 | Watkins William J. | Phosphonate substituted kinase inhibitors |
US7432272B2 (en) * | 2003-12-22 | 2008-10-07 | Gilead Sciences, Inc. | Antiviral analogs |
BRPI0418031A (pt) * | 2003-12-22 | 2007-04-17 | Gilead Sciences Inc | inibidores de quinase fosfonato-substituìdos |
TW200600492A (en) * | 2004-05-18 | 2006-01-01 | Achillion Pharmaceuticals Inc | Substituted aryl acylthioureas and related compounds; inhibitors of viral replication |
WO2006110157A2 (en) | 2004-07-27 | 2006-10-19 | Gilead Sciences, Inc. | Nucleoside phosphonate conjugates as anti hiv agents |
US20060264422A1 (en) * | 2005-05-09 | 2006-11-23 | Johannes Reinmueller | Use of taurolidine as enhancer of the complement system |
JP2009510122A (ja) * | 2005-09-29 | 2009-03-12 | ザ スクリプス リサーチ インスティテュート | ウイルスペプチドおよびフラビウイルス科のウイルスに対してウイルス感染を阻害するためのその使用 |
US7480400B2 (en) * | 2006-03-16 | 2009-01-20 | Siemens Medical Solutions Usa, Inc. | Detection of fiber pathways |
PL2307435T3 (pl) | 2008-07-08 | 2012-11-30 | Gilead Sciences Inc | Sole związków inhibitorów HIV |
PL3661937T3 (pl) | 2017-08-01 | 2021-12-20 | Gilead Sciences, Inc. | Formy krystaliczne ((s)-((((2r,5r)-5-(6-amino-9h-puryn-9-ylo)-4-fluoro-2,5-dihydrofuran-2-ylo)oksy)metylo)(fenoksy)fosforylo)-l-alaninianu etylu (gs-9131) do leczenia zakażeń wirusowych |
AU2019324089B2 (en) | 2018-08-21 | 2024-06-13 | Kyorin Pharmaceutical Co., Ltd. | Bicyclic heteroaromatic ring derivative |
CN112245570A (zh) * | 2019-07-22 | 2021-01-22 | 厦门特宝生物工程股份有限公司 | 一种基于干扰素的疾病治疗方法 |
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Publication number | Priority date | Publication date | Assignee | Title |
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US4353920A (en) * | 1980-08-25 | 1982-10-12 | Olin Corporation | Use of selected 3-trihalomethyl-5-ureido-1,2,4-oxadiazoles and -1,2,4-thiadiazoles as agricultural viricides |
JPS57136579A (en) * | 1981-01-21 | 1982-08-23 | Mitsui Toatsu Chem Inc | Thiazolylurea derivative, its preparation, and pharmaceutical composition containing the same |
US4835168A (en) * | 1985-12-16 | 1989-05-30 | Eli Lilly And Company | Thiadiazole antiviral agents |
US5256680A (en) * | 1988-11-29 | 1993-10-26 | Warner-Lambert Company | 3,5-di-tertiary-butyl-4-hydroxyphenyl-1,3,4-thiadiazoles, and oxadiazoles and 3,5-di-tertiary-butyl-4-hydroxy-phenyl-1,2,4-thiadazoles, oxadiazoles and triazoles as antiinflammatory agents |
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IL102548A (en) | 1991-08-02 | 1998-08-16 | Medivir Ab | Use of painting derivatives in the preparation of drugs for VIH inhibition and treatment of SDIA and new compounds |
JPH07149748A (ja) * | 1993-09-30 | 1995-06-13 | Souyaku Gijutsu Kenkyusho:Kk | チアジアゾール誘導体及びその製造法 |
JPH08169881A (ja) * | 1994-09-22 | 1996-07-02 | Soyaku Gijutsu Kenkyusho:Kk | アリールチアジアゾール誘導体及びそれを含有する抗ウイルス剤 |
JPH08245384A (ja) * | 1995-03-13 | 1996-09-24 | Soyaku Gijutsu Kenkyusho:Kk | 抗ウイルス剤 |
US6162791A (en) | 1998-03-02 | 2000-12-19 | Apotex Inc. | Thiadiazole compounds useful as inhibitors of cysteine activity dependent enzymes |
-
2000
- 2000-03-27 US US09/535,172 patent/US6258831B1/en not_active Expired - Fee Related
- 2000-03-29 AU AU41822/00A patent/AU763573B2/en not_active Ceased
- 2000-03-29 JP JP2000607629A patent/JP2002540156A/ja active Pending
- 2000-03-29 DE DE60020820T patent/DE60020820T2/de not_active Expired - Lifetime
- 2000-03-29 EP EP00921515A patent/EP1165070B1/en not_active Expired - Lifetime
- 2000-03-29 WO PCT/US2000/008421 patent/WO2000057878A1/en active IP Right Grant
- 2000-03-29 AT AT00921515T patent/ATE297729T1/de not_active IP Right Cessation
- 2000-03-29 CA CA002368615A patent/CA2368615C/en not_active Expired - Fee Related
- 2000-03-31 AR ARP000101499A patent/AR019505A1/es not_active Application Discontinuation
- 2000-03-31 CO CO00023489A patent/CO5160294A1/es unknown
- 2000-03-31 PE PE2000000287A patent/PE20001644A1/es not_active Application Discontinuation
-
2001
- 2001-03-19 US US09/812,094 patent/US6410575B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1165070A1 (en) | 2002-01-02 |
US20010031773A1 (en) | 2001-10-18 |
ATE297729T1 (de) | 2005-07-15 |
DE60020820T2 (de) | 2006-05-04 |
AU763573B2 (en) | 2003-07-24 |
AU4182200A (en) | 2000-10-16 |
JP2002540156A (ja) | 2002-11-26 |
DE60020820D1 (de) | 2005-07-21 |
WO2000057878A1 (en) | 2000-10-05 |
AR019505A1 (es) | 2002-02-20 |
PE20001644A1 (es) | 2001-02-06 |
CA2368615C (en) | 2007-01-02 |
US6258831B1 (en) | 2001-07-10 |
EP1165070B1 (en) | 2005-06-15 |
US6410575B2 (en) | 2002-06-25 |
CA2368615A1 (en) | 2000-10-05 |
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