CO5251424A1 - Oxazinquinolonas utiles en el tratamiento de infecciones virales - Google Patents

Oxazinquinolonas utiles en el tratamiento de infecciones virales

Info

Publication number
CO5251424A1
CO5251424A1 CO00074929A CO00074929A CO5251424A1 CO 5251424 A1 CO5251424 A1 CO 5251424A1 CO 00074929 A CO00074929 A CO 00074929A CO 00074929 A CO00074929 A CO 00074929A CO 5251424 A1 CO5251424 A1 CO 5251424A1
Authority
CO
Colombia
Prior art keywords
alkyl
oxazinquinolones
useful
treatment
viral infections
Prior art date
Application number
CO00074929A
Other languages
English (en)
Inventor
Steven Ronald Turner
Suvit Thaisrivongs
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of CO5251424A1 publication Critical patent/CO5251424A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Un compuesto de la fórmula I<EMI FILE="00074929_1" ID="1" IMF=JPEG >en donde R1 es C1-6 alquilo, substituido opcionalmente con -OH, -OC1-4 alquilo o het; en donde C1-6 alquilo está opcionalmente insaturado en forma parcial; en donde het es un radical de un anillo heterocíclico de cinco o seis miembros que tiene uno o dos heteroátomos seleccionados del grupo constituido de oxígeno, azufre y N; o una sal farmacéuticamente aceptable, racemato, solvato, tautómero, isómero óptico o derivado prodroga del mismo.
CO00074929A 1999-10-05 2000-10-03 Oxazinquinolonas utiles en el tratamiento de infecciones virales CO5251424A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15774299P 1999-10-05 1999-10-05

Publications (1)

Publication Number Publication Date
CO5251424A1 true CO5251424A1 (es) 2003-02-28

Family

ID=22565065

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00074929A CO5251424A1 (es) 1999-10-05 2000-10-03 Oxazinquinolonas utiles en el tratamiento de infecciones virales

Country Status (17)

Country Link
US (1) US6340680B1 (es)
EP (1) EP1220858B1 (es)
JP (1) JP2003511382A (es)
AR (1) AR032598A1 (es)
AT (1) ATE253578T1 (es)
AU (1) AU773098B2 (es)
CA (1) CA2382691A1 (es)
CO (1) CO5251424A1 (es)
DE (1) DE60006412T2 (es)
DK (1) DK1220858T3 (es)
ES (1) ES2210001T3 (es)
NZ (1) NZ518189A (es)
PE (1) PE20010598A1 (es)
PT (1) PT1220858E (es)
TW (1) TW500724B (es)
WO (1) WO2001025239A2 (es)
ZA (1) ZA200201556B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6673793B2 (en) 2000-07-12 2004-01-06 Pharmacia & Upjohn Co. Oxazinoquinolones useful for the treatment of viral infections
PT1299395E (pt) * 2000-07-12 2005-01-31 Upjohn Co Oxazinoquinolonas uteis para o tratamento de infeccoes provocadas por virus
US6624159B2 (en) * 2000-07-12 2003-09-23 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
US6821969B2 (en) * 2001-02-13 2004-11-23 Pharmacia & Upjohn Company Thioxazinoquinolones as antiviral agents
AU2002352882A1 (en) 2001-12-20 2003-07-09 Pharmacia And Upjohn Company Pyridoquinoxaline antivirals
JP2005530681A (ja) * 2001-12-20 2005-10-13 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー ピリドキノキサリン抗ウイルス剤
AU2003262946A1 (en) * 2002-08-30 2004-03-19 Pharmacia And Upjohn Company Method of preventing or treating atherosclerosis or restenosis
US20040186131A1 (en) * 2002-08-30 2004-09-23 Wathen Michael W Method of preventing or treating atherosclerosis or restenosis
EP1650192A4 (en) 2003-07-24 2007-03-21 Astellas Pharma Inc QUINOLONE DERIVATIVE OR SALT THEREOF
EP3849979A1 (en) 2018-09-12 2021-07-21 Novartis AG Antiviral pyridopyrazinedione compounds
AR120045A1 (es) 2019-09-26 2022-01-26 Novartis Ag Compuestos antivirales de pirazolopiridinona

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568649A (en) 1983-02-22 1986-02-04 Immunex Corporation Immediate ligand detection assay
US4870168A (en) 1987-02-26 1989-09-26 Bristol-Myers Company 3-Unsaturated alkyl cephems from 3-triflyl cephems
TW222276B (es) * 1992-01-27 1994-04-11 Fujisawa Pharmaceutical Co
US5792774A (en) 1996-02-21 1998-08-11 Chiroscience Limited Quinolones and their therapeutic use
EP0927164A1 (en) 1996-09-10 1999-07-07 PHARMACIA &amp; UPJOHN COMPANY 8-hydroxy-7-substituted quinolines as anti-viral agents

Also Published As

Publication number Publication date
ES2210001T3 (es) 2004-07-01
NZ518189A (en) 2004-05-28
US6340680B1 (en) 2002-01-22
PT1220858E (pt) 2004-03-31
PE20010598A1 (es) 2001-05-24
AR032598A1 (es) 2003-11-19
DE60006412T2 (de) 2004-08-26
DE60006412D1 (de) 2003-12-11
AU773098B2 (en) 2004-05-13
ZA200201556B (en) 2003-07-30
TW500724B (en) 2002-09-01
ATE253578T1 (de) 2003-11-15
EP1220858A2 (en) 2002-07-10
AU7700100A (en) 2001-05-10
WO2001025239A2 (en) 2001-04-12
CA2382691A1 (en) 2001-04-12
WO2001025239A3 (en) 2001-11-22
EP1220858B1 (en) 2003-11-05
JP2003511382A (ja) 2003-03-25
DK1220858T3 (da) 2004-01-26

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