NO20003496L - Nye aromatiske amider, fremgangsmÕte for fremstilling av disse, samt deres anvendelse som medisiner - Google Patents

Nye aromatiske amider, fremgangsmÕte for fremstilling av disse, samt deres anvendelse som medisiner

Info

Publication number
NO20003496L
NO20003496L NO20003496A NO20003496A NO20003496L NO 20003496 L NO20003496 L NO 20003496L NO 20003496 A NO20003496 A NO 20003496A NO 20003496 A NO20003496 A NO 20003496A NO 20003496 L NO20003496 L NO 20003496L
Authority
NO
Norway
Prior art keywords
medicines
processes
preparation
aromatic amides
new aromatic
Prior art date
Application number
NO20003496A
Other languages
English (en)
Norwegian (no)
Other versions
NO20003496D0 (no
Inventor
Jean-Luc Haesslein
Michel Klich
Patrick Laurin
Branislav Musicki
Anne-Marie Periers
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9800116A external-priority patent/FR2773369B1/fr
Priority claimed from FR9812936A external-priority patent/FR2784681B1/fr
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of NO20003496D0 publication Critical patent/NO20003496D0/no
Publication of NO20003496L publication Critical patent/NO20003496L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06Benzopyran radicals
    • C07H17/065Benzo[b]pyrans
    • C07H17/075Benzo[b]pyran-2-ones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
NO20003496A 1998-01-08 2000-07-07 Nye aromatiske amider, fremgangsmÕte for fremstilling av disse, samt deres anvendelse som medisiner NO20003496L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9800116A FR2773369B1 (fr) 1998-01-08 1998-01-08 Nouveaux amides aromatiques, leur procede de preparation et leur application comme medicaments
FR9812936A FR2784681B1 (fr) 1998-10-15 1998-10-15 Nouveaux amides aromatiques, leur procede de preparation et leur application comme medicaments
PCT/FR1999/000014 WO1999035155A1 (fr) 1998-01-08 1999-01-07 Nouveaux amides aromatiques, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
NO20003496D0 NO20003496D0 (no) 2000-07-07
NO20003496L true NO20003496L (no) 2000-09-08

Family

ID=26234055

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20003496A NO20003496L (no) 1998-01-08 2000-07-07 Nye aromatiske amider, fremgangsmÕte for fremstilling av disse, samt deres anvendelse som medisiner

Country Status (36)

Country Link
US (2) US6420538B1 (pt)
EP (1) EP1045856B1 (pt)
JP (1) JP2002500229A (pt)
KR (1) KR100604290B1 (pt)
CN (2) CN1269833C (pt)
AP (1) AP2000001857A0 (pt)
AR (1) AR015211A1 (pt)
AT (1) ATE236918T1 (pt)
AU (1) AU750742B2 (pt)
BR (1) BR9906819A (pt)
CA (1) CA2317951A1 (pt)
CO (1) CO4810298A1 (pt)
CZ (1) CZ299840B6 (pt)
DE (1) DE69906684T2 (pt)
DK (1) DK1045856T3 (pt)
DZ (1) DZ2702A1 (pt)
EA (1) EA003275B1 (pt)
ES (1) ES2192031T3 (pt)
HU (1) HUP0100847A3 (pt)
ID (1) ID27558A (pt)
IL (1) IL137201A0 (pt)
MA (1) MA26593A1 (pt)
NO (1) NO20003496L (pt)
NZ (1) NZ505523A (pt)
PA (1) PA8466601A1 (pt)
PE (1) PE20000175A1 (pt)
PL (1) PL193130B1 (pt)
PT (1) PT1045856E (pt)
RS (1) RS50047B (pt)
SA (1) SA99191247B1 (pt)
SI (1) SI1045856T1 (pt)
SK (1) SK284734B6 (pt)
TN (1) TNSN99003A1 (pt)
TR (1) TR200002009T2 (pt)
TW (1) TW538046B (pt)
WO (1) WO1999035155A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2749585B1 (fr) * 1996-06-11 1998-08-14 Hoechst Marion Roussel Inc Nouveaux derives aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
TW538046B (en) * 1998-01-08 2003-06-21 Hoechst Marion Roussel Inc Aromatic amides having antiobiotic activities and the preparation processes, intermediates and pharmaceutical composition thereof
US6916846B2 (en) 2000-05-12 2005-07-12 Merck & Co. Inc. Coumermycin analogs as chemical dimerizers of chimeric proteins
ATE375983T1 (de) 2000-12-15 2007-11-15 Vertex Pharma Bakterielle gyrase-hemmer und deren verwendung
FR2844273B1 (fr) * 2002-09-05 2008-04-04 Aventis Pharma Sa Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens.
US7439253B2 (en) * 2002-12-06 2008-10-21 Novexel Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
US8193352B2 (en) 2003-01-31 2012-06-05 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US7582641B2 (en) 2003-01-31 2009-09-01 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US7618974B2 (en) 2003-01-31 2009-11-17 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
AR042956A1 (es) 2003-01-31 2005-07-13 Vertex Pharma Inhibidores de girasa y usos de los mismos
US8404852B2 (en) 2003-01-31 2013-03-26 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US7569591B2 (en) 2003-01-31 2009-08-04 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
TW201026694A (en) 2008-12-12 2010-07-16 Astrazeneca Ab Compound 468
TW201026695A (en) 2008-12-12 2010-07-16 Astrazeneca Ab Piperidine compounds and uses thereof-596
TW201102065A (en) 2009-05-29 2011-01-16 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof
UY32856A (es) 2009-08-26 2011-03-31 Astrazeneca Ab Derivados heterocíclicos de urea y métodos de uso de los mismos
US8859620B2 (en) 2009-08-31 2014-10-14 University Of Notre Dame Du Lac Phthalanilate compounds and methods of use
WO2012097273A1 (en) 2011-01-14 2012-07-19 Vertex Pharmaceuticals Incorporated Solid forms of gyrase inhibitor (r)-1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl) pyrimidin-5-yl]-7-(tetrahydrofuran-2-yl)-1h-benzimidazol-2-yl]urea
AU2012205416B2 (en) 2011-01-14 2017-02-02 Spero Therapeutics, Inc. Solid forms of gyrase inhibitor (R)-1-ethyl-3-(5-(2-{1-hydroxy-1-methyl-ethyl}pyrimidin-5-yl)-7-(tetrahydrofuran-2-yl}-1H-benzimidazol-2-yl)urea
US8481551B2 (en) 2011-01-14 2013-07-09 Vertex Pharmaceuticals Incorporated Gyrase and topoisomerase IV inhibitors
PT2663556E (pt) 2011-01-14 2014-11-27 Vertex Pharma Processo de fabrico de inibidores de girase e topoisomerase iv
JP5977344B2 (ja) 2011-06-20 2016-08-24 バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated ジャイレースおよびトポイソメラーゼ阻害剤のリン酸エステル
AR093226A1 (es) 2012-07-18 2015-05-27 Vertex Pharma Formas solidas de dihidrogeno fosfato de (r)-2-(5-(2-(3-etilureido)-6-fluoro-7-(tetrahidrofuran-2-il)-1h-benzo[d]imidazol-5-il)pirimidin-2-il)propan-2-ilo y sus sales
US9572809B2 (en) 2012-07-18 2017-02-21 Spero Trinem, Inc. Combination therapy to treat Mycobacterium diseases
US20210323957A1 (en) 2018-09-03 2021-10-21 Univerza V Ljubljani New class of dna gyrase and/or topoisomerase iv inhibitors with activity against gram-positive and gram-negative bacteria
EP4263503A1 (en) 2020-12-17 2023-10-25 Univerza V Ljubljani New n-phenylpyrrolamide inhibitors of dna gyrase and topoisomerase iv with antibacterial activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226978A (en) * 1978-03-13 1980-10-07 Miles Laboratories, Inc. β-Galactosyl-umbelliferone-labeled aminoglycoside antibiotics and intermediates in their preparation
ATE207889T1 (de) 1996-03-20 2001-11-15 Aventis Pharma Sa Trizyclische verbindungen mit wirkung auf integrine, besonders auf das alphavbeta3-integrin,verfahren zur ihrer herstellung und zwischenprodukte des verfahrens, ihre verwendung als arzneimittel und sie enthaltende pharmazeutische zusammensetzungen
FR2749585B1 (fr) * 1996-06-11 1998-08-14 Hoechst Marion Roussel Inc Nouveaux derives aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
TW538046B (en) * 1998-01-08 2003-06-21 Hoechst Marion Roussel Inc Aromatic amides having antiobiotic activities and the preparation processes, intermediates and pharmaceutical composition thereof

Also Published As

Publication number Publication date
NZ505523A (en) 2003-01-31
TR200002009T2 (tr) 2001-05-21
IL137201A0 (en) 2001-07-24
TW538046B (en) 2003-06-21
DE69906684D1 (de) 2003-05-15
ID27558A (id) 2001-04-12
AP2000001857A0 (en) 2000-09-30
DK1045856T3 (da) 2003-07-21
PA8466601A1 (es) 2000-05-24
PL193130B1 (pl) 2007-01-31
CZ299840B6 (cs) 2008-12-10
CN1269833C (zh) 2006-08-16
ATE236918T1 (de) 2003-04-15
SK284734B6 (sk) 2005-10-06
TNSN99003A1 (fr) 2005-11-10
DE69906684T2 (de) 2003-11-06
CO4810298A1 (es) 1999-06-30
SA99191247B1 (ar) 2006-09-20
BR9906819A (pt) 2000-10-17
SK10152000A3 (sk) 2001-07-10
AU1973699A (en) 1999-07-26
EA200000749A1 (ru) 2000-12-25
RS50047B (sr) 2008-11-28
US20030060609A1 (en) 2003-03-27
PL341590A1 (en) 2001-04-23
EP1045856A1 (fr) 2000-10-25
EA003275B1 (ru) 2003-04-24
WO1999035155A1 (fr) 1999-07-15
PE20000175A1 (es) 2000-03-09
US6420538B1 (en) 2002-07-16
HUP0100847A1 (hu) 2001-07-30
HUP0100847A3 (en) 2003-07-28
ES2192031T3 (es) 2003-09-16
AR015211A1 (es) 2001-04-18
US6583119B2 (en) 2003-06-24
MA26593A1 (fr) 2004-12-20
PT1045856E (pt) 2003-08-29
YU42700A (sh) 2002-12-10
JP2002500229A (ja) 2002-01-08
CN1291988A (zh) 2001-04-18
AU750742B2 (en) 2002-07-25
CA2317951A1 (fr) 1999-07-15
SI1045856T1 (en) 2003-08-31
DZ2702A1 (fr) 2003-09-01
KR100604290B1 (ko) 2006-07-28
NO20003496D0 (no) 2000-07-07
CN1502617A (zh) 2004-06-09
KR20010033939A (ko) 2001-04-25
CN1257164C (zh) 2006-05-24
EP1045856B1 (fr) 2003-04-09
CZ20002523A3 (cs) 2000-11-15

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