ATE236918T1 - Aromatische amide, ihrer verfahren zur herstellung ung verwendung als arzneimitteln - Google Patents
Aromatische amide, ihrer verfahren zur herstellung ung verwendung als arzneimittelnInfo
- Publication number
- ATE236918T1 ATE236918T1 AT99900500T AT99900500T ATE236918T1 AT E236918 T1 ATE236918 T1 AT E236918T1 AT 99900500 T AT99900500 T AT 99900500T AT 99900500 T AT99900500 T AT 99900500T AT E236918 T1 ATE236918 T1 AT E236918T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- medicinal products
- aromatic amides
- amides
- aromatic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/06—Benzopyran radicals
- C07H17/065—Benzo[b]pyrans
- C07H17/075—Benzo[b]pyran-2-ones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9800116A FR2773369B1 (fr) | 1998-01-08 | 1998-01-08 | Nouveaux amides aromatiques, leur procede de preparation et leur application comme medicaments |
| FR9812936A FR2784681B1 (fr) | 1998-10-15 | 1998-10-15 | Nouveaux amides aromatiques, leur procede de preparation et leur application comme medicaments |
| PCT/FR1999/000014 WO1999035155A1 (fr) | 1998-01-08 | 1999-01-07 | Nouveaux amides aromatiques, leur procede de preparation et leur application comme medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE236918T1 true ATE236918T1 (de) | 2003-04-15 |
Family
ID=26234055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99900500T ATE236918T1 (de) | 1998-01-08 | 1999-01-07 | Aromatische amide, ihrer verfahren zur herstellung ung verwendung als arzneimitteln |
Country Status (36)
| Country | Link |
|---|---|
| US (2) | US6420538B1 (de) |
| EP (1) | EP1045856B1 (de) |
| JP (1) | JP2002500229A (de) |
| KR (1) | KR100604290B1 (de) |
| CN (2) | CN1257164C (de) |
| AP (1) | AP2000001857A0 (de) |
| AR (1) | AR015211A1 (de) |
| AT (1) | ATE236918T1 (de) |
| AU (1) | AU750742B2 (de) |
| BR (1) | BR9906819A (de) |
| CA (1) | CA2317951A1 (de) |
| CO (1) | CO4810298A1 (de) |
| CZ (1) | CZ299840B6 (de) |
| DE (1) | DE69906684T2 (de) |
| DK (1) | DK1045856T3 (de) |
| DZ (1) | DZ2702A1 (de) |
| EA (1) | EA003275B1 (de) |
| ES (1) | ES2192031T3 (de) |
| HU (1) | HUP0100847A3 (de) |
| ID (1) | ID27558A (de) |
| IL (1) | IL137201A0 (de) |
| MA (1) | MA26593A1 (de) |
| NO (1) | NO20003496L (de) |
| NZ (1) | NZ505523A (de) |
| PA (1) | PA8466601A1 (de) |
| PE (1) | PE20000175A1 (de) |
| PL (1) | PL193130B1 (de) |
| PT (1) | PT1045856E (de) |
| RS (1) | RS50047B (de) |
| SA (1) | SA99191247B1 (de) |
| SI (1) | SI1045856T1 (de) |
| SK (1) | SK284734B6 (de) |
| TN (1) | TNSN99003A1 (de) |
| TR (1) | TR200002009T2 (de) |
| TW (1) | TW538046B (de) |
| WO (1) | WO1999035155A1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2749585B1 (fr) * | 1996-06-11 | 1998-08-14 | Hoechst Marion Roussel Inc | Nouveaux derives aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments |
| TW538046B (en) * | 1998-01-08 | 2003-06-21 | Hoechst Marion Roussel Inc | Aromatic amides having antiobiotic activities and the preparation processes, intermediates and pharmaceutical composition thereof |
| US6916846B2 (en) | 2000-05-12 | 2005-07-12 | Merck & Co. Inc. | Coumermycin analogs as chemical dimerizers of chimeric proteins |
| MXPA03005298A (es) | 2000-12-15 | 2003-10-06 | Vertex Pharma | Inhibidores de girasa y usos de los mismos. |
| FR2844273B1 (fr) * | 2002-09-05 | 2008-04-04 | Aventis Pharma Sa | Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens. |
| US7439253B2 (en) * | 2002-12-06 | 2008-10-21 | Novexel | Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors |
| US8193352B2 (en) | 2003-01-31 | 2012-06-05 | Vertex Pharmaceuticals Incorporated | Gyrase inhibitors and uses thereof |
| US7618974B2 (en) | 2003-01-31 | 2009-11-17 | Vertex Pharmaceuticals Incorporated | Gyrase inhibitors and uses thereof |
| US7569591B2 (en) | 2003-01-31 | 2009-08-04 | Vertex Pharmaceuticals Incorporated | Gyrase inhibitors and uses thereof |
| US7582641B2 (en) | 2003-01-31 | 2009-09-01 | Vertex Pharmaceuticals Incorporated | Gyrase inhibitors and uses thereof |
| US8404852B2 (en) | 2003-01-31 | 2013-03-26 | Vertex Pharmaceuticals Incorporated | Gyrase inhibitors and uses thereof |
| AR042956A1 (es) | 2003-01-31 | 2005-07-13 | Vertex Pharma | Inhibidores de girasa y usos de los mismos |
| US8071605B2 (en) | 2008-12-12 | 2011-12-06 | Astrazeneca Ab | Piperidine compounds for use in the treatment of bacterial infections |
| TW201026694A (en) | 2008-12-12 | 2010-07-16 | Astrazeneca Ab | Compound 468 |
| TW201102065A (en) | 2009-05-29 | 2011-01-16 | Astrazeneca Ab | Heterocyclic urea derivatives and methods of use thereof |
| TW201111380A (en) | 2009-08-26 | 2011-04-01 | Astrazeneca Ab | Heterocyclic urea derivatives and methods of use thereof |
| WO2011026107A1 (en) | 2009-08-31 | 2011-03-03 | University Of Notre Dame Du Lac | Phthalanilate compounds and methods of use |
| EP2663558A1 (de) | 2011-01-14 | 2013-11-20 | Vertex Pharmaceuticals Incorporated | Feste formen von gyrasehemmer-(r)-1-ethyl-3-[5-[2-{1-hydroxy-1-methyl-ethyl-}pyrimidin-5-yl-]7-(tetrahydrofuran-2-yl-)-1h-benzimidazol-2-yl-]harnstoff |
| AU2012205420B2 (en) | 2011-01-14 | 2016-12-08 | Spero Therapeutics, Inc. | Process of making gyrase and topoisomerase IV inhibitors |
| KR101897952B1 (ko) | 2011-01-14 | 2018-09-12 | 스페로 트리넴, 인코포레이티드 | 피리미딘 자이라제 및 토포이소머라제 ｉｖ 억제제 |
| MX341342B (es) | 2011-01-14 | 2016-08-17 | Vertex Pharma | Formas solidas del inhibidor de girasa (r)-1-etil-3-[6-fluoro-5-[2 -(1-hidroxi-1-metil-etil) pirimidin-5-il]-7-(tetrahidrofuran-2-il) -1h-benzimidazol-2-il]urea. |
| KR101941420B1 (ko) | 2011-06-20 | 2019-01-23 | 스페로 트리넴, 인코포레이티드 | 자이라제 및 토포이소머라제 억제제의 인산에스테르 |
| WO2014015105A1 (en) | 2012-07-18 | 2014-01-23 | Vertex Pharmaceuticals Incorporated | Solid forms of (r)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1h-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate and salts thereof |
| US9572809B2 (en) | 2012-07-18 | 2017-02-21 | Spero Trinem, Inc. | Combination therapy to treat Mycobacterium diseases |
| WO2020048949A1 (en) | 2018-09-03 | 2020-03-12 | Univerza V Ljubljani | New class of dna gyrase and/or topoisomerase iv inhibitors with activity against gram-positive and gram-negative bacteria |
| EP4263503A1 (de) | 2020-12-17 | 2023-10-25 | Univerza V Ljubljani | Neue n-phenylpyrrolamid-inhibitoren der dna-gyrase und topoisomerase iv mit antibakterieller wirkung |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4226978A (en) * | 1978-03-13 | 1980-10-07 | Miles Laboratories, Inc. | β-Galactosyl-umbelliferone-labeled aminoglycoside antibiotics and intermediates in their preparation |
| US6221907B1 (en) | 1996-03-20 | 2001-04-24 | Hoechst Marion Roussel | Tricyclic compounds having activity specific for integrins, particularly alphanubeta3 integrins, method for preparing same, intermediates therefor, use of said compounds as drugs, and pharmaceutical compositions containing same |
| FR2749585B1 (fr) | 1996-06-11 | 1998-08-14 | Hoechst Marion Roussel Inc | Nouveaux derives aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments |
| TW538046B (en) * | 1998-01-08 | 2003-06-21 | Hoechst Marion Roussel Inc | Aromatic amides having antiobiotic activities and the preparation processes, intermediates and pharmaceutical composition thereof |
-
1998
- 1998-12-18 TW TW087121194A patent/TW538046B/zh not_active IP Right Cessation
-
1999
- 1999-01-06 DZ DZ990003A patent/DZ2702A1/xx active
- 1999-01-06 MA MA25418A patent/MA26593A1/fr unknown
- 1999-01-07 PT PT99900500T patent/PT1045856E/pt unknown
- 1999-01-07 RS YUP-427/00A patent/RS50047B/sr unknown
- 1999-01-07 CA CA002317951A patent/CA2317951A1/fr not_active Abandoned
- 1999-01-07 AU AU19736/99A patent/AU750742B2/en not_active Revoked
- 1999-01-07 SI SI9930174T patent/SI1045856T1/xx unknown
- 1999-01-07 DE DE69906684T patent/DE69906684T2/de not_active Expired - Fee Related
- 1999-01-07 KR KR1020007007523A patent/KR100604290B1/ko not_active IP Right Cessation
- 1999-01-07 BR BR9906819-2A patent/BR9906819A/pt not_active Application Discontinuation
- 1999-01-07 PA PA19998466601A patent/PA8466601A1/es unknown
- 1999-01-07 ID IDW20001325A patent/ID27558A/id unknown
- 1999-01-07 SK SK1015-2000A patent/SK284734B6/sk not_active IP Right Cessation
- 1999-01-07 CZ CZ20002523A patent/CZ299840B6/cs not_active IP Right Cessation
- 1999-01-07 CN CNB2003101141348A patent/CN1257164C/zh not_active Expired - Fee Related
- 1999-01-07 DK DK99900500T patent/DK1045856T3/da active
- 1999-01-07 AT AT99900500T patent/ATE236918T1/de not_active IP Right Cessation
- 1999-01-07 CN CNB998035033A patent/CN1269833C/zh not_active Expired - Fee Related
- 1999-01-07 NZ NZ505523A patent/NZ505523A/xx unknown
- 1999-01-07 EA EA200000749A patent/EA003275B1/ru not_active IP Right Cessation
- 1999-01-07 IL IL13720199A patent/IL137201A0/xx unknown
- 1999-01-07 WO PCT/FR1999/000014 patent/WO1999035155A1/fr active IP Right Grant
- 1999-01-07 HU HU0100847A patent/HUP0100847A3/hu unknown
- 1999-01-07 EP EP99900500A patent/EP1045856B1/de not_active Expired - Lifetime
- 1999-01-07 JP JP2000527551A patent/JP2002500229A/ja active Pending
- 1999-01-07 ES ES99900500T patent/ES2192031T3/es not_active Expired - Lifetime
- 1999-01-07 US US09/600,053 patent/US6420538B1/en not_active Expired - Fee Related
- 1999-01-07 AP APAP/P/2000/001857A patent/AP2000001857A0/en unknown
- 1999-01-07 TR TR2000/02009T patent/TR200002009T2/xx unknown
- 1999-01-08 TN TNTNSN99003A patent/TNSN99003A1/fr unknown
- 1999-01-08 AR ARP990100061A patent/AR015211A1/es not_active Application Discontinuation
- 1999-01-08 CO CO99001031A patent/CO4810298A1/es unknown
- 1999-01-08 PE PE1999000017A patent/PE20000175A1/es not_active Application Discontinuation
- 1999-04-05 SA SA99191247A patent/SA99191247B1/ar unknown
-
2000
- 2000-07-07 NO NO20003496A patent/NO20003496L/no not_active Application Discontinuation
- 2000-08-31 PL PL341590A patent/PL193130B1/pl not_active IP Right Cessation
-
2002
- 2002-06-05 US US10/162,852 patent/US6583119B2/en not_active Expired - Fee Related
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1045856 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |