PA8466601A1 - Nuevas amidas aromaticas, su procedimiento de preparacion y su aplicacion como medicamentos - Google Patents

Nuevas amidas aromaticas, su procedimiento de preparacion y su aplicacion como medicamentos

Info

Publication number
PA8466601A1
PA8466601A1 PA19998466601A PA8466601A PA8466601A1 PA 8466601 A1 PA8466601 A1 PA 8466601A1 PA 19998466601 A PA19998466601 A PA 19998466601A PA 8466601 A PA8466601 A PA 8466601A PA 8466601 A1 PA8466601 A1 PA 8466601A1
Authority
PA
Panama
Prior art keywords
medicines
application
preparation procedure
aromatic amides
new aromatic
Prior art date
Application number
PA19998466601A
Other languages
English (en)
Inventor
Branislav Musicki
Jean-Luc Haesslein
Michel Klich
Patrick Laurin
Anne-Marie Periers
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9800116A external-priority patent/FR2773369B1/fr
Priority claimed from FR9812936A external-priority patent/FR2784681B1/fr
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of PA8466601A1 publication Critical patent/PA8466601A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/075—Benzo[b]pyran-2-ones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

ESTA INVENCION SE REFIERE A NUEVAS AMIDAS AROMATICAS, A SU PROCEDIMIENTO DE PREPARACION Y SU APLICACION COMO MEDICAMENTOS.
PA19998466601A 1998-01-08 1999-01-07 Nuevas amidas aromaticas, su procedimiento de preparacion y su aplicacion como medicamentos PA8466601A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9800116A FR2773369B1 (fr) 1998-01-08 1998-01-08 Nouveaux amides aromatiques, leur procede de preparation et leur application comme medicaments
FR9812936A FR2784681B1 (fr) 1998-10-15 1998-10-15 Nouveaux amides aromatiques, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
PA8466601A1 true PA8466601A1 (es) 2000-05-24

Family

ID=26234055

Family Applications (1)

Application Number Title Priority Date Filing Date
PA19998466601A PA8466601A1 (es) 1998-01-08 1999-01-07 Nuevas amidas aromaticas, su procedimiento de preparacion y su aplicacion como medicamentos

Country Status (36)

Country Link
US (2) US6420538B1 (es)
EP (1) EP1045856B1 (es)
JP (1) JP2002500229A (es)
KR (1) KR100604290B1 (es)
CN (2) CN1257164C (es)
AP (1) AP2000001857A0 (es)
AR (1) AR015211A1 (es)
AT (1) ATE236918T1 (es)
AU (1) AU750742B2 (es)
BR (1) BR9906819A (es)
CA (1) CA2317951A1 (es)
CO (1) CO4810298A1 (es)
CZ (1) CZ299840B6 (es)
DE (1) DE69906684T2 (es)
DK (1) DK1045856T3 (es)
DZ (1) DZ2702A1 (es)
EA (1) EA003275B1 (es)
ES (1) ES2192031T3 (es)
HU (1) HUP0100847A3 (es)
ID (1) ID27558A (es)
IL (1) IL137201A0 (es)
MA (1) MA26593A1 (es)
NO (1) NO20003496L (es)
NZ (1) NZ505523A (es)
PA (1) PA8466601A1 (es)
PE (1) PE20000175A1 (es)
PL (1) PL193130B1 (es)
PT (1) PT1045856E (es)
RS (1) RS50047B (es)
SA (1) SA99191247B1 (es)
SI (1) SI1045856T1 (es)
SK (1) SK284734B6 (es)
TN (1) TNSN99003A1 (es)
TR (1) TR200002009T2 (es)
TW (1) TW538046B (es)
WO (1) WO1999035155A1 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2749585B1 (fr) * 1996-06-11 1998-08-14 Hoechst Marion Roussel Inc Nouveaux derives aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
TW538046B (en) * 1998-01-08 2003-06-21 Hoechst Marion Roussel Inc Aromatic amides having antiobiotic activities and the preparation processes, intermediates and pharmaceutical composition thereof
US6916846B2 (en) 2000-05-12 2005-07-12 Merck & Co. Inc. Coumermycin analogs as chemical dimerizers of chimeric proteins
MY138797A (en) 2000-12-15 2009-07-31 Vertex Pharma Bacterial gyrase inhibitors and uses thereof
FR2844273B1 (fr) * 2002-09-05 2008-04-04 Aventis Pharma Sa Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens.
US7439253B2 (en) * 2002-12-06 2008-10-21 Novexel Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
US8193352B2 (en) 2003-01-31 2012-06-05 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US7569591B2 (en) 2003-01-31 2009-08-04 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US8404852B2 (en) 2003-01-31 2013-03-26 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
AR042956A1 (es) 2003-01-31 2005-07-13 Vertex Pharma Inhibidores de girasa y usos de los mismos
US7582641B2 (en) 2003-01-31 2009-09-01 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US7618974B2 (en) 2003-01-31 2009-11-17 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
TW201026695A (en) 2008-12-12 2010-07-16 Astrazeneca Ab Piperidine compounds and uses thereof-596
TW201026694A (en) 2008-12-12 2010-07-16 Astrazeneca Ab Compound 468
TW201102065A (en) 2009-05-29 2011-01-16 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof
WO2011024004A1 (en) 2009-08-26 2011-03-03 Astrazeneca Ab Heterocyclic urea derivatives useful for treatment of bacterial infection
WO2011026107A1 (en) 2009-08-31 2011-03-03 University Of Notre Dame Du Lac Phthalanilate compounds and methods of use
AU2012205419B2 (en) 2011-01-14 2016-12-15 Spero Therapeutics, Inc. Solid forms of gyrase inhibitor (R)-1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl) pyrimidin-5-yl]-7-(tetrahydrofuran-2-yl)-1H-benzimidazol-2-yl]urea
AU2012205420B2 (en) 2011-01-14 2016-12-08 Spero Therapeutics, Inc. Process of making gyrase and topoisomerase IV inhibitors
TW201309676A (zh) 2011-01-14 2013-03-01 Vertex Pharma 旋轉酶抑制劑（ｒ）－１－乙基－３－［５－［２－（１－羥基－１－甲基－乙基）嘧啶－５－基］－７－（四氫呋喃－２－基］－１ｈ－苯并咪唑－２－基］脲之固體形式
EP2663557B1 (en) 2011-01-14 2015-05-27 Vertex Pharmaceuticals Incorporated Pyrimidine gyrase and topoisomerase iv inhibitors
JP5977344B2 (ja) 2011-06-20 2016-08-24 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ ジャイレースおよびトポイソメラーゼ阻害剤のリン酸エステル
US9018216B2 (en) 2012-07-18 2015-04-28 Vertex Pharmaceuticals Incorporated Solid forms of (R)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1H-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate and salts thereof
WO2014014845A1 (en) 2012-07-18 2014-01-23 Vertex Pharmaceuticals Incorporated Combination therapy comprising|1 -ethyl-3-[5-[2-{1 -hydroxy-1 -methyl-ethyl}pyrimidin-5-yl]-7-(tetra hydrofuran-2-|yl}-1 h-benzimidazol-2-yl]urea and derivatives thereof to treat mycobacterium|diseases
WO2020048949A1 (en) 2018-09-03 2020-03-12 Univerza V Ljubljani New class of dna gyrase and/or topoisomerase iv inhibitors with activity against gram-positive and gram-negative bacteria
WO2022129327A1 (en) 2020-12-17 2022-06-23 Univerza V Ljubljani New n-phenylpyrrolamide inhibitors of dna gyrase and topoisomerase iv with antibacterial activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226978A (en) * 1978-03-13 1980-10-07 Miles Laboratories, Inc. β-Galactosyl-umbelliferone-labeled aminoglycoside antibiotics and intermediates in their preparation
GEP20012516B (en) 1996-03-20 2001-08-27 Genentech Inc Tricyclic Compounds Having Activity Specific for Integring, Particularly , avB3 Integrins, Method for Preparation the Same as Drugs and Pharmaceutical Composition Containing Same
FR2749585B1 (fr) * 1996-06-11 1998-08-14 Hoechst Marion Roussel Inc Nouveaux derives aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
TW538046B (en) * 1998-01-08 2003-06-21 Hoechst Marion Roussel Inc Aromatic amides having antiobiotic activities and the preparation processes, intermediates and pharmaceutical composition thereof

Also Published As

Publication number Publication date
ATE236918T1 (de) 2003-04-15
DK1045856T3 (da) 2003-07-21
IL137201A0 (en) 2001-07-24
EP1045856A1 (fr) 2000-10-25
DE69906684T2 (de) 2003-11-06
AU1973699A (en) 1999-07-26
PL341590A1 (en) 2001-04-23
CA2317951A1 (fr) 1999-07-15
EA200000749A1 (ru) 2000-12-25
AU750742B2 (en) 2002-07-25
MA26593A1 (fr) 2004-12-20
SA99191247B1 (ar) 2006-09-20
CN1291988A (zh) 2001-04-18
EA003275B1 (ru) 2003-04-24
CO4810298A1 (es) 1999-06-30
CZ299840B6 (cs) 2008-12-10
EP1045856B1 (fr) 2003-04-09
KR20010033939A (ko) 2001-04-25
PL193130B1 (pl) 2007-01-31
AP2000001857A0 (en) 2000-09-30
PE20000175A1 (es) 2000-03-09
NO20003496L (no) 2000-09-08
DE69906684D1 (de) 2003-05-15
CN1269833C (zh) 2006-08-16
SK284734B6 (sk) 2005-10-06
SI1045856T1 (en) 2003-08-31
US6420538B1 (en) 2002-07-16
HUP0100847A3 (en) 2003-07-28
YU42700A (sh) 2002-12-10
JP2002500229A (ja) 2002-01-08
PT1045856E (pt) 2003-08-29
TNSN99003A1 (fr) 2005-11-10
US6583119B2 (en) 2003-06-24
WO1999035155A1 (fr) 1999-07-15
TW538046B (en) 2003-06-21
NO20003496D0 (no) 2000-07-07
CZ20002523A3 (cs) 2000-11-15
RS50047B (sr) 2008-11-28
SK10152000A3 (sk) 2001-07-10
AR015211A1 (es) 2001-04-18
HUP0100847A1 (hu) 2001-07-30
ID27558A (id) 2001-04-12
BR9906819A (pt) 2000-10-17
US20030060609A1 (en) 2003-03-27
ES2192031T3 (es) 2003-09-16
CN1502617A (zh) 2004-06-09
NZ505523A (en) 2003-01-31
CN1257164C (zh) 2006-05-24
KR100604290B1 (ko) 2006-07-28
TR200002009T2 (tr) 2001-05-21
DZ2702A1 (fr) 2003-09-01

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