ID27558A - Amida-amida aromatik baru, metode pembuatannya dan penggunaannya sebagai obat - Google Patents

Amida-amida aromatik baru, metode pembuatannya dan penggunaannya sebagai obat

Info

Publication number
ID27558A
ID27558A IDW20001325A ID20001325A ID27558A ID 27558 A ID27558 A ID 27558A ID W20001325 A IDW20001325 A ID W20001325A ID 20001325 A ID20001325 A ID 20001325A ID 27558 A ID27558 A ID 27558A
Authority
ID
Indonesia
Prior art keywords
medicine
making
aromatic amides
new aromatic
new
Prior art date
Application number
IDW20001325A
Other languages
English (en)
Indonesian (id)
Inventor
Jean-Luc Haesslein
Michel Klich
Patrick Laurin
Branislav Musicki
Anne-Marie Perers
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9800116A external-priority patent/FR2773369B1/fr
Priority claimed from FR9812936A external-priority patent/FR2784681B1/fr
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of ID27558A publication Critical patent/ID27558A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06Benzopyran radicals
    • C07H17/065Benzo[b]pyrans
    • C07H17/075Benzo[b]pyran-2-ones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
IDW20001325A 1998-01-08 1999-01-07 Amida-amida aromatik baru, metode pembuatannya dan penggunaannya sebagai obat ID27558A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9800116A FR2773369B1 (fr) 1998-01-08 1998-01-08 Nouveaux amides aromatiques, leur procede de preparation et leur application comme medicaments
FR9812936A FR2784681B1 (fr) 1998-10-15 1998-10-15 Nouveaux amides aromatiques, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
ID27558A true ID27558A (id) 2001-04-12

Family

ID=26234055

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20001325A ID27558A (id) 1998-01-08 1999-01-07 Amida-amida aromatik baru, metode pembuatannya dan penggunaannya sebagai obat

Country Status (36)

Country Link
US (2) US6420538B1 (pt)
EP (1) EP1045856B1 (pt)
JP (1) JP2002500229A (pt)
KR (1) KR100604290B1 (pt)
CN (2) CN1269833C (pt)
AP (1) AP2000001857A0 (pt)
AR (1) AR015211A1 (pt)
AT (1) ATE236918T1 (pt)
AU (1) AU750742B2 (pt)
BR (1) BR9906819A (pt)
CA (1) CA2317951A1 (pt)
CO (1) CO4810298A1 (pt)
CZ (1) CZ299840B6 (pt)
DE (1) DE69906684T2 (pt)
DK (1) DK1045856T3 (pt)
DZ (1) DZ2702A1 (pt)
EA (1) EA003275B1 (pt)
ES (1) ES2192031T3 (pt)
HU (1) HUP0100847A3 (pt)
ID (1) ID27558A (pt)
IL (1) IL137201A0 (pt)
MA (1) MA26593A1 (pt)
NO (1) NO20003496L (pt)
NZ (1) NZ505523A (pt)
PA (1) PA8466601A1 (pt)
PE (1) PE20000175A1 (pt)
PL (1) PL193130B1 (pt)
PT (1) PT1045856E (pt)
RS (1) RS50047B (pt)
SA (1) SA99191247B1 (pt)
SI (1) SI1045856T1 (pt)
SK (1) SK284734B6 (pt)
TN (1) TNSN99003A1 (pt)
TR (1) TR200002009T2 (pt)
TW (1) TW538046B (pt)
WO (1) WO1999035155A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2749585B1 (fr) * 1996-06-11 1998-08-14 Hoechst Marion Roussel Inc Nouveaux derives aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
TW538046B (en) * 1998-01-08 2003-06-21 Hoechst Marion Roussel Inc Aromatic amides having antiobiotic activities and the preparation processes, intermediates and pharmaceutical composition thereof
US6916846B2 (en) 2000-05-12 2005-07-12 Merck & Co. Inc. Coumermycin analogs as chemical dimerizers of chimeric proteins
HUP0303494A3 (en) * 2000-12-15 2009-08-28 Vertex Pharma Parmaceutical compositions containing bacterial gyrase inhibitors and uses thereof
FR2844273B1 (fr) * 2002-09-05 2008-04-04 Aventis Pharma Sa Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens.
US7439253B2 (en) * 2002-12-06 2008-10-21 Novexel Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
US7569591B2 (en) 2003-01-31 2009-08-04 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US8193352B2 (en) 2003-01-31 2012-06-05 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US7618974B2 (en) 2003-01-31 2009-11-17 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US8404852B2 (en) 2003-01-31 2013-03-26 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
AR042956A1 (es) 2003-01-31 2005-07-13 Vertex Pharma Inhibidores de girasa y usos de los mismos
US7582641B2 (en) 2003-01-31 2009-09-01 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US8071605B2 (en) 2008-12-12 2011-12-06 Astrazeneca Ab Piperidine compounds for use in the treatment of bacterial infections
TW201026694A (en) 2008-12-12 2010-07-16 Astrazeneca Ab Compound 468
TW201102065A (en) 2009-05-29 2011-01-16 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof
UY32856A (es) 2009-08-26 2011-03-31 Astrazeneca Ab Derivados heterocíclicos de urea y métodos de uso de los mismos
US8859620B2 (en) 2009-08-31 2014-10-14 University Of Notre Dame Du Lac Phthalanilate compounds and methods of use
RU2609259C2 (ru) 2011-01-14 2017-01-31 Сперо Тринем, Инк. Пиримидиновые ингибиторы гиразы и топоизомеразы iv
BR112013017985B1 (pt) 2011-01-14 2021-06-29 Spero Therapeutics Inc. Formas sólidas de inibidor de girase (r)-1-etil-3-[6-flúor-5-[2-(1-hidróxi-1-metil-etil)pirimidin- 5-il]-7-(tetra-hidrofuran-2-il)-1h-benzimidazol-2-il]ureia, seu sal de ácido clorídrico, método de preparação das mesmas e composição farmacêutica que os compreende
RU2013137753A (ru) 2011-01-14 2015-02-20 Вертекс Фармасьютикалз Инкорпорейтед Твердые формы ингибитора гиразы (r)-1-этил-3-[5-[2-(1-гидрокси-1-метилэтил)пиримидин-5-ил]-7-(тетрагидрофуран-2-ил)-1н-бензимидазол-2-ил]мочевины
AU2012205420B2 (en) 2011-01-14 2016-12-08 Spero Therapeutics, Inc. Process of making gyrase and topoisomerase IV inhibitors
EP2721026B1 (en) 2011-06-20 2016-03-02 Vertex Pharmaceuticals Incorporated Phosphate esters of gyrase and topoisomerase inhibitors
TWI595002B (zh) 2012-07-18 2017-08-11 思沛羅三南公司 (R)-2-(5-(2-(3-乙基脲基)-6-氟-7-(四氫呋喃-2-基)-1H-苯并[d]咪唑-5-基)嘧啶-2-基)丙烷-2-基磷酸二氫鹽之固體形式及其鹽
US9572809B2 (en) 2012-07-18 2017-02-21 Spero Trinem, Inc. Combination therapy to treat Mycobacterium diseases
WO2020048949A1 (en) 2018-09-03 2020-03-12 Univerza V Ljubljani New class of dna gyrase and/or topoisomerase iv inhibitors with activity against gram-positive and gram-negative bacteria
WO2022129327A1 (en) 2020-12-17 2022-06-23 Univerza V Ljubljani New n-phenylpyrrolamide inhibitors of dna gyrase and topoisomerase iv with antibacterial activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226978A (en) * 1978-03-13 1980-10-07 Miles Laboratories, Inc. β-Galactosyl-umbelliferone-labeled aminoglycoside antibiotics and intermediates in their preparation
ATE207889T1 (de) 1996-03-20 2001-11-15 Aventis Pharma Sa Trizyclische verbindungen mit wirkung auf integrine, besonders auf das alphavbeta3-integrin,verfahren zur ihrer herstellung und zwischenprodukte des verfahrens, ihre verwendung als arzneimittel und sie enthaltende pharmazeutische zusammensetzungen
FR2749585B1 (fr) * 1996-06-11 1998-08-14 Hoechst Marion Roussel Inc Nouveaux derives aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
TW538046B (en) * 1998-01-08 2003-06-21 Hoechst Marion Roussel Inc Aromatic amides having antiobiotic activities and the preparation processes, intermediates and pharmaceutical composition thereof

Also Published As

Publication number Publication date
CA2317951A1 (fr) 1999-07-15
NO20003496L (no) 2000-09-08
CZ20002523A3 (cs) 2000-11-15
SK284734B6 (sk) 2005-10-06
AR015211A1 (es) 2001-04-18
NZ505523A (en) 2003-01-31
SI1045856T1 (en) 2003-08-31
DZ2702A1 (fr) 2003-09-01
PA8466601A1 (es) 2000-05-24
ES2192031T3 (es) 2003-09-16
KR20010033939A (ko) 2001-04-25
HUP0100847A1 (hu) 2001-07-30
AP2000001857A0 (en) 2000-09-30
AU750742B2 (en) 2002-07-25
HUP0100847A3 (en) 2003-07-28
BR9906819A (pt) 2000-10-17
YU42700A (sh) 2002-12-10
IL137201A0 (en) 2001-07-24
EA003275B1 (ru) 2003-04-24
CZ299840B6 (cs) 2008-12-10
TNSN99003A1 (fr) 2005-11-10
JP2002500229A (ja) 2002-01-08
CN1291988A (zh) 2001-04-18
EP1045856A1 (fr) 2000-10-25
PT1045856E (pt) 2003-08-29
DE69906684T2 (de) 2003-11-06
WO1999035155A1 (fr) 1999-07-15
ATE236918T1 (de) 2003-04-15
CN1502617A (zh) 2004-06-09
TW538046B (en) 2003-06-21
CN1269833C (zh) 2006-08-16
SA99191247B1 (ar) 2006-09-20
EP1045856B1 (fr) 2003-04-09
CO4810298A1 (es) 1999-06-30
PE20000175A1 (es) 2000-03-09
DE69906684D1 (de) 2003-05-15
SK10152000A3 (sk) 2001-07-10
RS50047B (sr) 2008-11-28
US6583119B2 (en) 2003-06-24
PL341590A1 (en) 2001-04-23
KR100604290B1 (ko) 2006-07-28
PL193130B1 (pl) 2007-01-31
US6420538B1 (en) 2002-07-16
US20030060609A1 (en) 2003-03-27
EA200000749A1 (ru) 2000-12-25
DK1045856T3 (da) 2003-07-21
NO20003496D0 (no) 2000-07-07
AU1973699A (en) 1999-07-26
TR200002009T2 (tr) 2001-05-21
CN1257164C (zh) 2006-05-24
MA26593A1 (fr) 2004-12-20

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