NO20001169L - 6,9-bro erythromycinderivater - Google Patents

6,9-bro erythromycinderivater

Info

Publication number
NO20001169L
NO20001169L NO20001169A NO20001169A NO20001169L NO 20001169 L NO20001169 L NO 20001169L NO 20001169 A NO20001169 A NO 20001169A NO 20001169 A NO20001169 A NO 20001169A NO 20001169 L NO20001169 L NO 20001169L
Authority
NO
Norway
Prior art keywords
bridge
compound
pharmaceutically acceptable
effective amount
therapeutically effective
Prior art date
Application number
NO20001169A
Other languages
English (en)
Other versions
NO20001169D0 (no
Inventor
Yat Sun Or
Richard F Clark
Daniel T Chu
Jacob J Plattner
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of NO20001169D0 publication Critical patent/NO20001169D0/no
Publication of NO20001169L publication Critical patent/NO20001169L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Nye multicykliske erytromycinforbindelser og farmasøy- tisk akseptable salter og estere derav som har antibak- teriell aktivitet hvilke har formel (I), (II) eller (III), sammensetninger omfattende en terapeutisk effek- tiv mengde av en forbindelse av oppfinnelsen i kombina- sjon med en farmasøytisk akseptabel bærer, samt en be- .handlingsfremgangsmåte ved bakterielle infeksjoner ved å administrere til et pattedyr en farmasøytisk sammen- setning inneholdende en terapeutisk effektiv mengde av en forbindelse av oppfinnelsen.
NO20001169A 1997-09-08 2000-03-07 6,9-bro erythromycinderivater NO20001169L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/925,582 US5780605A (en) 1997-09-08 1997-09-08 6,9-bridged erythromycin derivatives
PCT/US1998/018225 WO1999012947A1 (en) 1997-09-08 1998-09-01 6,9-bridged erythromycin derivatives

Publications (2)

Publication Number Publication Date
NO20001169D0 NO20001169D0 (no) 2000-03-07
NO20001169L true NO20001169L (no) 2000-04-05

Family

ID=25451953

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20001169A NO20001169L (no) 1997-09-08 2000-03-07 6,9-bro erythromycinderivater

Country Status (24)

Country Link
US (1) US5780605A (no)
EP (1) EP1015467B1 (no)
JP (1) JP2001515915A (no)
KR (1) KR20010023756A (no)
CN (1) CN1269803A (no)
AR (1) AR015434A1 (no)
AT (1) ATE257484T1 (no)
AU (1) AU9216298A (no)
BG (1) BG104288A (no)
BR (1) BR9812148A (no)
CA (1) CA2301643A1 (no)
CO (1) CO4970722A1 (no)
DE (1) DE69821009T2 (no)
DK (1) DK1015467T3 (no)
ES (1) ES2213915T3 (no)
HU (1) HUP0003571A2 (no)
IL (1) IL134220A0 (no)
NO (1) NO20001169L (no)
PL (1) PL339137A1 (no)
PT (1) PT1015467E (no)
SK (1) SK3032000A3 (no)
TR (1) TR200000620T2 (no)
WO (1) WO1999012947A1 (no)
ZA (1) ZA987688B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7273853B2 (en) * 2002-05-13 2007-09-25 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
US7910558B2 (en) * 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US6841664B2 (en) * 2002-07-25 2005-01-11 Enanra Pharmaceuticals, Inc. 6,11-4-carbon bridged ketolides
US7464097B2 (en) * 2002-08-16 2008-12-09 Sap Ag Managing data integrity using a filter condition
TW200420573A (en) * 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
EP1599491A1 (en) * 2003-03-05 2005-11-30 Rib-X Pharmaceuticals, Inc. Bifunctional heterocyclic compounds and methods of making and using the same
JP2007509980A (ja) * 2003-10-30 2007-04-19 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 二官能性マクロライド複素環式化合物およびそれらの化合物を調製および使用する方法
EP1699808A1 (en) * 2003-11-18 2006-09-13 Rib-X Pharmaceuticals, Inc. Bifunctional macrolide heterocyclic compounds and methods of making and using the same
US7414030B2 (en) * 2004-01-07 2008-08-19 Enanta Pharmaceuticals, Inc. 6-11 Bicyclic erythromycin derivatives
WO2005070113A2 (en) * 2004-01-09 2005-08-04 Enanta Pharmaceuticals, Inc. 9n-substituted 6-11 bicyclic erythromycin derivatives
WO2005080408A1 (en) * 2004-01-23 2005-09-01 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US7384921B2 (en) * 2004-02-20 2008-06-10 Enanta Pharmaceuticals, Inc. Polymorphic forms of 6-11 bicyclic ketolide derivatives
US8202843B2 (en) * 2004-02-27 2012-06-19 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
US7384922B2 (en) * 2005-05-04 2008-06-10 Enanta Pharmaceuticals, Inc. 6-11 bridged oxime erythromycin derivatives
US20060252710A1 (en) * 2005-05-04 2006-11-09 Guoqiang Wang 6-11 Bridged oxime erythromycin derivatives
JP2008540432A (ja) * 2005-05-04 2008-11-20 エナンタ ファーマシューティカルズ インコーポレイテッド ６−１１橋かけオキシムエリスロマイシン誘導体
US8273720B2 (en) * 2007-09-17 2012-09-25 Enanta Pharmaceuticals, Inc. 6,11-bicyclolides: bridged biaryl macrolide derivatives
US8354383B2 (en) * 2007-09-17 2013-01-15 Enanta Pharmaceuticals, Inc. 6,11-bridged biaryl macrolides
US20090075915A1 (en) * 2007-09-17 2009-03-19 In Jong Kim 6,11-bicyclolides: bridged biaryl macrolide derivatives
TW200946109A (en) * 2008-05-09 2009-11-16 Enanta Pharm Inc Anti-bacterial activity of 9-hydroxy derivatives 6, 11-bicyclolides

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6248696A (ja) * 1985-08-27 1987-03-03 Kanegafuchi Chem Ind Co Ltd Ｎ−〔１（ｓ）−エトキシカルボニル−３−フエニルプロピル〕−ｌ−アラニル−ｌ−プロリンの製造法
KR960000434B1 (ko) * 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
KR0179379B1 (ko) * 1992-01-21 1999-04-01 찰스 엠.브록 4"-데옥시에리트로마이신 유도체
KR0166996B1 (ko) * 1992-04-22 1999-01-15 우에하라 아키라 5-o-데소사미닐에리쓰로노라이드a 유도체
MY113693A (en) * 1992-05-26 2002-05-31 Chugai Pharmaceutical Co Ltd Erythromycin derivatives having an enterokinesis stimulating action
HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5712253A (en) * 1996-06-18 1998-01-27 Abbott Laboratories Macrocyclic 13-membered ring derivatives of erythromycins A and B

Also Published As

Publication number Publication date
EP1015467A1 (en) 2000-07-05
BR9812148A (pt) 2000-07-18
AU9216298A (en) 1999-03-29
PT1015467E (pt) 2004-05-31
ZA987688B (en) 1999-02-24
HUP0003571A2 (hu) 2001-02-28
NO20001169D0 (no) 2000-03-07
SK3032000A3 (en) 2000-07-11
BG104288A (bg) 2001-01-31
AR015434A1 (es) 2001-05-02
CO4970722A1 (es) 2000-11-07
JP2001515915A (ja) 2001-09-25
EP1015467B1 (en) 2004-01-07
KR20010023756A (ko) 2001-03-26
DE69821009D1 (de) 2004-02-12
CN1269803A (zh) 2000-10-11
DE69821009T2 (de) 2004-11-18
ES2213915T3 (es) 2004-09-01
TR200000620T2 (tr) 2000-09-21
PL339137A1 (en) 2000-12-04
ATE257484T1 (de) 2004-01-15
US5780605A (en) 1998-07-14
IL134220A0 (en) 2001-04-30
DK1015467T3 (da) 2004-05-03
WO1999012947A1 (en) 1999-03-18
CA2301643A1 (en) 1999-03-18

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FC2A Withdrawal, rejection or dismissal of laid open patent application