DK1015467T3 - 6,9-brobundne erythromycinderivater - Google Patents

6,9-brobundne erythromycinderivater

Info

Publication number
DK1015467T3
DK1015467T3 DK98944680T DK98944680T DK1015467T3 DK 1015467 T3 DK1015467 T3 DK 1015467T3 DK 98944680 T DK98944680 T DK 98944680T DK 98944680 T DK98944680 T DK 98944680T DK 1015467 T3 DK1015467 T3 DK 1015467T3
Authority
DK
Denmark
Prior art keywords
erythromycin derivatives
bridged erythromycin
bridged
derivatives
erythromycin
Prior art date
Application number
DK98944680T
Other languages
English (en)
Inventor
Yat Sun Or
Richard F Clark
Daniel T Chu
Jacob J Plattner
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK1015467T3 publication Critical patent/DK1015467T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
DK98944680T 1997-09-08 1998-09-01 6,9-brobundne erythromycinderivater DK1015467T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/925,582 US5780605A (en) 1997-09-08 1997-09-08 6,9-bridged erythromycin derivatives
PCT/US1998/018225 WO1999012947A1 (en) 1997-09-08 1998-09-01 6,9-bridged erythromycin derivatives

Publications (1)

Publication Number Publication Date
DK1015467T3 true DK1015467T3 (da) 2004-05-03

Family

ID=25451953

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98944680T DK1015467T3 (da) 1997-09-08 1998-09-01 6,9-brobundne erythromycinderivater

Country Status (24)

Country Link
US (1) US5780605A (da)
EP (1) EP1015467B1 (da)
JP (1) JP2001515915A (da)
KR (1) KR20010023756A (da)
CN (1) CN1269803A (da)
AR (1) AR015434A1 (da)
AT (1) ATE257484T1 (da)
AU (1) AU9216298A (da)
BG (1) BG104288A (da)
BR (1) BR9812148A (da)
CA (1) CA2301643A1 (da)
CO (1) CO4970722A1 (da)
DE (1) DE69821009T2 (da)
DK (1) DK1015467T3 (da)
ES (1) ES2213915T3 (da)
HU (1) HUP0003571A2 (da)
IL (1) IL134220A0 (da)
NO (1) NO20001169L (da)
PL (1) PL339137A1 (da)
PT (1) PT1015467E (da)
SK (1) SK3032000A3 (da)
TR (1) TR200000620T2 (da)
WO (1) WO1999012947A1 (da)
ZA (1) ZA987688B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6841664B2 (en) * 2002-07-25 2005-01-11 Enanra Pharmaceuticals, Inc. 6,11-4-carbon bridged ketolides
US7273853B2 (en) * 2002-05-13 2007-09-25 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
US7910558B2 (en) * 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US7464097B2 (en) * 2002-08-16 2008-12-09 Sap Ag Managing data integrity using a filter condition
AR043050A1 (es) * 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
WO2004078770A1 (en) * 2003-03-05 2004-09-16 Rib-X Pharmaceuticals, Inc. Bifunctional heterocyclic compounds and methods of making and using the same
WO2005042554A1 (en) * 2003-10-30 2005-05-12 Rib-X Pharmaceuticals, Inc. Bifunctional macrolide heterocyclic compounds and methods of making and using the same
WO2005049632A1 (en) * 2003-11-18 2005-06-02 Rib-X Pharmaceuticals, Inc. Bifunctional macrolide heterocyclic compounds and methods of making and using the same
US7414030B2 (en) * 2004-01-07 2008-08-19 Enanta Pharmaceuticals, Inc. 6-11 Bicyclic erythromycin derivatives
WO2005070113A2 (en) * 2004-01-09 2005-08-04 Enanta Pharmaceuticals, Inc. 9n-substituted 6-11 bicyclic erythromycin derivatives
WO2005080408A1 (en) * 2004-01-23 2005-09-01 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US7384921B2 (en) * 2004-02-20 2008-06-10 Enanta Pharmaceuticals, Inc. Polymorphic forms of 6-11 bicyclic ketolide derivatives
WO2005085266A2 (en) 2004-02-27 2005-09-15 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
US7384922B2 (en) * 2005-05-04 2008-06-10 Enanta Pharmaceuticals, Inc. 6-11 bridged oxime erythromycin derivatives
EP1885737A4 (en) * 2005-05-04 2010-11-24 Enanta Pharm Inc 6-11-bridged OXIM-ERYTHROMYCIN DERIVATIVES
US20060252710A1 (en) * 2005-05-04 2006-11-09 Guoqiang Wang 6-11 Bridged oxime erythromycin derivatives
US8354383B2 (en) * 2007-09-17 2013-01-15 Enanta Pharmaceuticals, Inc. 6,11-bridged biaryl macrolides
CN104004039A (zh) * 2007-09-17 2014-08-27 英安塔制药有限公司 6,11-桥联的联芳大环内酯类
US8273720B2 (en) * 2007-09-17 2012-09-25 Enanta Pharmaceuticals, Inc. 6,11-bicyclolides: bridged biaryl macrolide derivatives
TW200946109A (en) * 2008-05-09 2009-11-16 Enanta Pharm Inc Anti-bacterial activity of 9-hydroxy derivatives 6, 11-bicyclolides

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6248696A (ja) * 1985-08-27 1987-03-03 Kanegafuchi Chem Ind Co Ltd Ｎ−〔１（ｓ）−エトキシカルボニル−３−フエニルプロピル〕−ｌ−アラニル−ｌ−プロリンの製造法
KR960000434B1 (ko) * 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
MX9300278A (es) * 1992-01-21 1993-12-31 Abbott Lab Compuestos de arilalcoxifenoxi-imidazolina.
WO1993021200A1 (fr) * 1992-04-22 1993-10-28 Taisho Pharmaceutical Co., Ltd. Derive de 5-o-desosaminylerythronolide a
MY113693A (en) * 1992-05-26 2002-05-31 Chugai Pharmaceutical Co Ltd Erythromycin derivatives having an enterokinesis stimulating action
HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5712253A (en) * 1996-06-18 1998-01-27 Abbott Laboratories Macrocyclic 13-membered ring derivatives of erythromycins A and B

Also Published As

Publication number Publication date
AR015434A1 (es) 2001-05-02
TR200000620T2 (tr) 2000-09-21
KR20010023756A (ko) 2001-03-26
SK3032000A3 (en) 2000-07-11
IL134220A0 (en) 2001-04-30
CO4970722A1 (es) 2000-11-07
US5780605A (en) 1998-07-14
PL339137A1 (en) 2000-12-04
DE69821009T2 (de) 2004-11-18
HUP0003571A2 (hu) 2001-02-28
NO20001169L (no) 2000-04-05
ATE257484T1 (de) 2004-01-15
EP1015467B1 (en) 2004-01-07
DE69821009D1 (de) 2004-02-12
BR9812148A (pt) 2000-07-18
PT1015467E (pt) 2004-05-31
ZA987688B (en) 1999-02-24
JP2001515915A (ja) 2001-09-25
AU9216298A (en) 1999-03-29
EP1015467A1 (en) 2000-07-05
CN1269803A (zh) 2000-10-11
NO20001169D0 (no) 2000-03-07
CA2301643A1 (en) 1999-03-18
BG104288A (bg) 2001-01-31
ES2213915T3 (es) 2004-09-01
WO1999012947A1 (en) 1999-03-18

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