NO20000464L - Acykliske metalloprotease-inhibitorer - Google Patents

Acykliske metalloprotease-inhibitorer

Info

Publication number
NO20000464L
NO20000464L NO20000464A NO20000464A NO20000464L NO 20000464 L NO20000464 L NO 20000464L NO 20000464 A NO20000464 A NO 20000464A NO 20000464 A NO20000464 A NO 20000464A NO 20000464 L NO20000464 L NO 20000464L
Authority
NO
Norway
Prior art keywords
acyclic
metalloprotease inhibitors
metalloprotease
inhibitors
acyclic metalloprotease
Prior art date
Application number
NO20000464A
Other languages
English (en)
Norwegian (no)
Other versions
NO20000464D0 (no
Inventor
Neil Gregory Almstead
Roger Gunnard Bookland
Yetunde Olabisi Taiwo
Rimma Sandler Bradley
Rodney Dean Bush
Biswanath De
Michael George Natchus
Stanislaw Pikul
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of NO20000464D0 publication Critical patent/NO20000464D0/no
Publication of NO20000464L publication Critical patent/NO20000464L/no

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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
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    • C07D207/408—Radicals containing only hydrogen and carbon atoms attached to ring carbon atoms
    • C07D207/412—Acyclic radicals containing more than six carbon atoms
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    • C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
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    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/36—Amides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms

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NO20000464A 1997-07-31 2000-01-28 Acykliske metalloprotease-inhibitorer NO20000464L (no)

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US5434897P 1997-07-31 1997-07-31
PCT/IB1998/001139 WO1999006340A2 (en) 1997-07-31 1998-07-27 Sulfonylamino substituted hydroxamic acid derivatives as metalloprotease inhibitors

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WO1999006340A2 (en) 1999-02-11
HUP0004595A3 (en) 2001-12-28
EP1009737A2 (en) 2000-06-21
IL134273A0 (en) 2001-04-30
AU746877B2 (en) 2002-05-02
CN1265647A (zh) 2000-09-06
ZA986835B (en) 1999-02-01
AU8237698A (en) 1999-02-22
BR9810841A (pt) 2001-07-10
CA2298617A1 (en) 1999-02-11
AR012264A1 (es) 2000-09-27
NO20000464D0 (no) 2000-01-28
JP2001513484A (ja) 2001-09-04
HUP0004595A2 (hu) 2001-08-28
PE115399A1 (es) 2000-02-02
KR20010022499A (ko) 2001-03-15
WO1999006340A3 (en) 1999-09-30
NZ503945A (en) 2002-11-26
US6218389B1 (en) 2001-04-17
KR100352316B1 (ko) 2002-09-12

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