NO176203C - Fremgangsmåte for fremstilling av ibuprofentabletter med forsinket frigjöring - Google Patents

Fremgangsmåte for fremstilling av ibuprofentabletter med forsinket frigjöring

Info

Publication number
NO176203C
NO176203C NO881732A NO881732A NO176203C NO 176203 C NO176203 C NO 176203C NO 881732 A NO881732 A NO 881732A NO 881732 A NO881732 A NO 881732A NO 176203 C NO176203 C NO 176203C
Authority
NO
Norway
Prior art keywords
ibuprofen
granulation
delayed
preparation
erosion
Prior art date
Application number
NO881732A
Other languages
English (en)
Other versions
NO176203B (no
NO881732D0 (no
NO881732L (no
Inventor
Galen Wesley Radebaugh
Thomas Nicholas Julian
Robert Glineche
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of NO881732D0 publication Critical patent/NO881732D0/no
Publication of NO881732L publication Critical patent/NO881732L/no
Publication of NO176203B publication Critical patent/NO176203B/no
Publication of NO176203C publication Critical patent/NO176203C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO881732A 1987-04-22 1988-04-21 Fremgangsmåte for fremstilling av ibuprofentabletter med forsinket frigjöring NO176203C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/041,164 US4806359A (en) 1987-04-22 1987-04-22 Iburprofen sustained release matrix and process

Publications (4)

Publication Number Publication Date
NO881732D0 NO881732D0 (no) 1988-04-21
NO881732L NO881732L (no) 1988-10-24
NO176203B NO176203B (no) 1994-11-14
NO176203C true NO176203C (no) 1995-02-22

Family

ID=21915089

Family Applications (1)

Application Number Title Priority Date Filing Date
NO881732A NO176203C (no) 1987-04-22 1988-04-21 Fremgangsmåte for fremstilling av ibuprofentabletter med forsinket frigjöring

Country Status (21)

Country Link
US (1) US4806359A (no)
EP (2) EP0290168B1 (no)
JP (2) JP2519296B2 (no)
KR (1) KR960007750B1 (no)
AT (1) ATE86479T1 (no)
AU (2) AU604110B2 (no)
CA (1) CA1310272C (no)
DE (2) DE3865077D1 (no)
ES (1) ES2039277T3 (no)
GR (1) GR1000019B (no)
HK (1) HK22892A (no)
IE (1) IE62786B1 (no)
IN (1) IN165929B (no)
MY (1) MY103076A (no)
NO (1) NO176203C (no)
NZ (1) NZ224278A (no)
PH (1) PH25176A (no)
PT (1) PT87285B (no)
SG (1) SG104091G (no)
WO (1) WO1988008299A1 (no)
ZA (1) ZA882827B (no)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5200193A (en) * 1987-04-22 1993-04-06 Mcneilab, Inc. Pharmaceutical sustained release matrix and process
US4999226A (en) * 1988-06-01 1991-03-12 Merrell Dow Pharmaceuticals Inc. Pharmaceutical compositions for piperidinoalkanol-ibuprofen combination
AU4664889A (en) * 1988-11-30 1990-06-26 Schering Corporation Sustained release diltiazem formulation
US5104648A (en) * 1989-02-02 1992-04-14 Mallinckrodt Specialty Chemicals Company High ibuprofen content granulations
US4911921A (en) * 1989-02-02 1990-03-27 Mallinckrodt, Inc. High ibuprofen content granulations
US5085865A (en) * 1989-04-12 1992-02-04 Warner-Lambert Company Sustained release pharmaceutical preparations containing an analgesic and a decongestant
KR920002148A (ko) * 1990-07-03 1992-02-28 안드레아 엘. 콜비 비스테로이드계 소염제에 의해 유발된 위장 증상을 완화시키기 위한 약제 조성물 및 이를 완화시키는 방법
FR2677886B1 (fr) * 1991-06-18 1995-03-31 Adir Comprime matriciel permettant la liberation prolongee d'indapamide apres administration par voie orale.
DE4140172C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Ibuprofen enthaltendes Arzneimittel
DE4140184C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Akutform für ein Flurbiprofen enthaltendes Arzneimittel
DE4140183C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Flurbiprofen enthaltendes Arzneimittel
DE4140179C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Akutform für ein Ibuprofen enthaltendes Arzneimittel
DE4140185C2 (de) * 1991-12-05 1996-02-01 Alfatec Pharma Gmbh Ein 2-Arylpropionsäurederivat in Nanosolform enthaltendes Arzneimittel und seine Herstellung
DK138592D0 (da) * 1992-11-17 1992-11-17 Nycomed Dak As Tabletter
US20080075781A1 (en) * 1992-11-25 2008-03-27 Purdue Pharma Lp Controlled release oxycodone compositions
US20070275062A1 (en) * 1993-06-18 2007-11-29 Benjamin Oshlack Controlled release oxycodone compositions
IT1264696B1 (it) * 1993-07-09 1996-10-04 Applied Pharma Res Forme farmaceutiche destinate alla somministrazione orale in grado di rilasciare sostanze attive a velocita' controllata e differenziata
WO1995035099A1 (en) * 1994-06-20 1995-12-28 Kv Pharmaceutical Company Vitamin/nutrient dosage regimentation
WO1996012476A1 (en) * 1994-10-20 1996-05-02 Merck & Co., Inc. Wet granulation formulation for a piperazinylcamphorsulfonyl oxytocin receptor antagonist
IT1276689B1 (it) * 1995-06-09 1997-11-03 Applied Pharma Res Forma farmaceutica solida ad uso orale
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
JP3628809B2 (ja) * 1996-06-10 2005-03-16 アルケア株式会社 薬剤徐放性医療用配合物及びその製造方法
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
US6361796B1 (en) 1996-10-25 2002-03-26 Shire Laboratories, Inc. Soluble form osmotic dose delivery system
EP0954291B1 (en) * 1996-10-25 2005-12-28 Shire Laboratories Inc. Soluble form osmotic dose delivery system
CZ300551B6 (cs) * 1999-03-31 2009-06-17 Janssen Pharmaceutica N. V. Predželatinovaný škrob v rízene se uvolnující formulaci
CO5200844A1 (es) * 1999-09-17 2002-09-27 Novartis Ag Una combinacion que comprende nateglinida y cuando por menos otro compuesto antidiabetico usada para el tratamiento de desordenes metabolicos, especialmente diabetes, o de una enfermedad o condicion asociada con dibetes
WO2002062320A1 (en) * 2001-02-05 2002-08-15 R.P. Scherer Technologies, Inc. Methods and compositions for reducing the taste of pharmaceutically active agents
US6602911B2 (en) * 2001-11-05 2003-08-05 Cypress Bioscience, Inc. Methods of treating fibromyalgia
AU2003225837B2 (en) * 2002-03-15 2008-11-06 Forest Laboratories Holdings Limited NE and 5-HT reuptake inhibitors for treating visceral pain syndromes
US20060003004A1 (en) * 2002-10-25 2006-01-05 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
US20040132826A1 (en) * 2002-10-25 2004-07-08 Collegium Pharmaceutical, Inc. Modified release compositions of milnacipran
AU2004207578B2 (en) * 2003-01-28 2007-06-28 Collegium Pharmaceutical, Inc. Multiparticulate compositions of milnacipran for oral administration
EP1648407A4 (en) * 2003-07-21 2011-08-31 Middlebrook Pharmaceuticals Inc ANTIBIOTIC PRODUCT, CORRESPONDING USE AND FORMULATION
US8425936B2 (en) * 2003-07-21 2013-04-23 Shionogi Inc. Antibiotic product, use and formulation thereof
WO2005009365A2 (en) 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
JP2007502294A (ja) 2003-08-12 2007-02-08 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
WO2005023184A2 (en) * 2003-08-29 2005-03-17 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
JP2007513869A (ja) * 2003-09-15 2007-05-31 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
NZ546182A (en) * 2003-09-26 2009-08-28 Alza Corp Controlled release formulations of opioid and nonopioid analgesics such as hydrocodone and acetaminophen
EP1708684A2 (en) 2003-09-26 2006-10-11 Alza Corporation Drug coating providing high drug loading and methods for providing the same
WO2005030182A1 (en) * 2003-09-26 2005-04-07 Alza Corporation Controlled release formulations exhibiting an ascending rate of release
JP5670609B2 (ja) * 2003-09-26 2015-02-18 アルザ・コーポレーシヨン 有効成分の制御送達のためのｏｒｏｓプッシュ−スティック
EP1765296A2 (en) 2004-06-30 2007-03-28 Albemarle Corporation High ibuprofen content granules and their preparation and use
US8541026B2 (en) 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US20070077297A1 (en) 2004-09-30 2007-04-05 Scolr Pharma, Inc. Modified release ibuprofen dosage form
US20060099253A1 (en) * 2004-10-20 2006-05-11 Wyeth Antibiotic product formulation
US8431156B2 (en) * 2005-02-22 2013-04-30 Sun Pharma Advanced Research Company Ltd. Pharmaceutical composition
DE102005037630A1 (de) 2005-08-09 2007-02-15 Glatt Gmbh Verfahren zur Herstellung von Teilchen aus pharmazeutischen Substanzen, Teilchen aus pharmazeutischen Substanzen sowie deren Verwendung
US7994220B2 (en) * 2005-09-28 2011-08-09 Cypress Bioscience, Inc. Milnacipran for the long-term treatment of fibromyalgia syndrome
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
GB0525461D0 (en) 2005-12-15 2006-01-25 Archimedes Dev Ltd Pharmaceutical compositions
CN101330904B (zh) * 2005-12-16 2012-04-18 韩美控股株式会社 含有低熔点活性成分的固体分散体以及含有它的口服给药片剂
US7749537B2 (en) 2006-12-04 2010-07-06 Scolr Pharma, Inc. Method of forming a tablet
US8623397B2 (en) 2007-04-13 2014-01-07 The Regents Of The University Of Michigan Delivery device and method for forming the same
US9629806B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
BRPI0917206B1 (pt) * 2008-07-31 2018-04-17 Clarke Mosquito Control Products, Inc. Método para a formação de uma pastilha comprimida de liberação dupla, pastilhas comprimidas e método para a fabricação de uma matriz sólida de liberação prolongada
EP2968652B1 (en) 2013-03-13 2020-07-22 Avery Dennison Corporation Improving adhesive properties
CN110037994B (zh) * 2019-05-24 2022-04-12 中国药科大学 一种布洛芬速释缓释双层片及其制备方法
CN114177155B (zh) * 2020-09-08 2023-10-03 越洋医药开发(广州)有限公司 一种布洛芬控释片及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773921A (en) * 1971-11-15 1973-11-20 Hoffmann La Roche Therapeutic compositions
US4264573A (en) * 1979-05-21 1981-04-28 Rowell Laboratories, Inc. Pharmaceutical formulation for slow release via controlled surface erosion
US4308251A (en) * 1980-01-11 1981-12-29 Boots Pharmaceuticals, Inc. Controlled release formulations of orally-active medicaments
US4465660A (en) * 1981-04-01 1984-08-14 Mead Johnson & Company Sustained release tablet containing at least 95 percent theophylline
FR2532177A1 (fr) * 1982-08-30 1984-03-02 Being Well Products Inc Complement nutritionnel a zones de liberation determinees et son procede de fabrication
US4684516A (en) * 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
CA1261260A (en) * 1984-04-16 1989-09-26 Anil Salpekar Directly compressible codeine salt compositions
US4753801A (en) * 1985-10-25 1988-06-28 Eli Lilly And Company Sustained release tablets

Also Published As

Publication number Publication date
DE3865077D1 (de) 1991-10-31
IE62786B1 (en) 1995-02-22
NO176203B (no) 1994-11-14
KR960007750B1 (ko) 1996-06-12
EP0290168B1 (en) 1991-09-25
KR880012213A (ko) 1988-11-26
NZ224278A (en) 1990-09-26
AU1719788A (en) 1988-12-02
PT87285B (pt) 1992-08-31
EP0290168A1 (en) 1988-11-09
EP0312581B1 (en) 1993-03-10
DE3879080D1 (de) 1993-04-15
ZA882827B (en) 1989-12-27
IE881195L (en) 1988-10-22
AU1477488A (en) 1988-10-27
MY103076A (en) 1993-04-30
ES2039277T3 (es) 1993-09-16
JPS63280021A (ja) 1988-11-17
SG104091G (en) 1992-02-14
WO1988008299A1 (en) 1988-11-03
PH25176A (en) 1991-03-27
AU604110B2 (en) 1990-12-06
PT87285A (pt) 1988-05-01
JP2519296B2 (ja) 1996-07-31
HK22892A (en) 1992-04-03
ATE86479T1 (de) 1993-03-15
AU603675B2 (en) 1990-11-22
DE3879080T2 (de) 1993-07-15
EP0312581A1 (en) 1989-04-26
CA1310272C (en) 1992-11-17
NO881732D0 (no) 1988-04-21
GR880100258A (en) 1989-01-31
US4806359A (en) 1989-02-21
IN165929B (no) 1990-02-10
GR1000019B (el) 1990-01-31
JP2776856B2 (ja) 1998-07-16
JPH01503070A (ja) 1989-10-19
NO881732L (no) 1988-10-24

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