NO160582C - Fremgangsmaate til fremstilling av vannopploeselige dialkalimetallsalter av 7-beta-/2-2(aminotiazol-4-yl)-2-syn-metoksiminoacetamido/-3-(5-karboksylmetyl-4-metyl-1,3-diazol-2-yl-tiometyl)-cef-3-em-4-karboksylsyre. - Google Patents
Fremgangsmaate til fremstilling av vannopploeselige dialkalimetallsalter av 7-beta-/2-2(aminotiazol-4-yl)-2-syn-metoksiminoacetamido/-3-(5-karboksylmetyl-4-metyl-1,3-diazol-2-yl-tiometyl)-cef-3-em-4-karboksylsyre.Info
- Publication number
- NO160582C NO160582C NO823625A NO823625A NO160582C NO 160582 C NO160582 C NO 160582C NO 823625 A NO823625 A NO 823625A NO 823625 A NO823625 A NO 823625A NO 160582 C NO160582 C NO 160582C
- Authority
- NO
- Norway
- Prior art keywords
- methyl
- ceph
- syn
- beta
- carboxylic acid
- Prior art date
Links
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title abstract 3
- IKWLIQXIPRUIDU-ZCFIWIBFSA-N (6r)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical compound OC(=O)C1=CCS[C@@H]2CC(=O)N12 IKWLIQXIPRUIDU-ZCFIWIBFSA-N 0.000 title abstract 2
- 125000000066 S-methyl group Chemical group [H]C([H])([H])S* 0.000 title 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical class [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813143537 DE3143537A1 (de) | 1981-11-03 | 1981-11-03 | Kristalline salze von cefodizim und verfahren zu ihrer herstellung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO823625L NO823625L (no) | 1983-05-04 |
| NO160582B NO160582B (no) | 1989-01-23 |
| NO160582C true NO160582C (no) | 1989-05-03 |
Family
ID=6145473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO823625A NO160582C (no) | 1981-11-03 | 1982-11-01 | Fremgangsmaate til fremstilling av vannopploeselige dialkalimetallsalter av 7-beta-/2-2(aminotiazol-4-yl)-2-syn-metoksiminoacetamido/-3-(5-karboksylmetyl-4-metyl-1,3-diazol-2-yl-tiometyl)-cef-3-em-4-karboksylsyre. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4590267A (instruction) |
| EP (1) | EP0078532B1 (instruction) |
| JP (1) | JPS5885893A (instruction) |
| KR (1) | KR880001412B1 (instruction) |
| AT (1) | ATE24729T1 (instruction) |
| CA (1) | CA1186682A (instruction) |
| CS (1) | CS415691A3 (instruction) |
| DE (2) | DE3143537A1 (instruction) |
| DK (1) | DK163360C (instruction) |
| ES (1) | ES517024A0 (instruction) |
| FI (1) | FI75573C (instruction) |
| GR (1) | GR76735B (instruction) |
| HU (1) | HU188604B (instruction) |
| IE (1) | IE54066B1 (instruction) |
| IL (1) | IL67134A (instruction) |
| MA (1) | MA19638A1 (instruction) |
| NO (1) | NO160582C (instruction) |
| NZ (1) | NZ202332A (instruction) |
| PH (1) | PH20488A (instruction) |
| PT (1) | PT75778A (instruction) |
| ZA (1) | ZA828004B (instruction) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0150507B1 (en) * | 1983-12-29 | 1992-08-05 | Mochida Pharmaceutical Co., Ltd. | Cephalosporin derivatives, processes for producing the same and compositions containing them |
| JPS60142987A (ja) * | 1983-12-29 | 1985-07-29 | Mochida Pharmaceut Co Ltd | セフアロスポリン誘導体 |
| DE3405728A1 (de) * | 1984-02-17 | 1985-08-22 | Hoechst Ag, 6230 Frankfurt | Verwendung von cephemverbindungen als immunmodulatoren |
| US4840945A (en) * | 1985-04-01 | 1989-06-20 | Mochida Pharmaceutical Co., Ltd. | Cephalosporin derivatives |
| US4880798A (en) * | 1986-11-25 | 1989-11-14 | Mochida Pharmaceutical Co., Ltd. | Cephalosporin derivatives |
| JPS63132893A (ja) * | 1986-11-25 | 1988-06-04 | Mochida Pharmaceut Co Ltd | 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤 |
| DE3911322A1 (de) * | 1989-04-07 | 1990-10-11 | Hoechst Ag | Verfahren zur herstellung von cefodizim-dinatrium |
| DE3923541A1 (de) * | 1989-07-15 | 1991-01-24 | Hoechst Ag | Cephalosporinderivate und verfahren zu ihrer herstellung |
| JP4731437B2 (ja) * | 2006-09-25 | 2011-07-27 | 株式会社オーディオテクニカ | コンデンサーマイクロホンユニットおよびコンデンサーマイクロホン |
| CN101723958B (zh) * | 2008-10-22 | 2011-12-21 | 丽珠医药集团股份有限公司 | 头孢地嗪钠药物及制备方法 |
| CN101830915A (zh) * | 2010-05-13 | 2010-09-15 | 胡梨芳 | 头孢地嗪钠水合物及其制备方法和用途 |
| CN102796118B (zh) * | 2012-05-29 | 2013-12-04 | 浙江亚太药业股份有限公司 | 一种头孢地嗪钠化合物实体、制备方法及其药物制剂 |
| CN102898443B (zh) * | 2012-10-31 | 2015-12-16 | 天津青松华药医药有限公司 | 高收率超净高纯化头孢地嗪钠的精制方法 |
| CN104031066B (zh) * | 2014-05-21 | 2016-06-29 | 丽珠医药集团股份有限公司 | 一种头孢地嗪钠药物及制备方法 |
| CN108976247A (zh) * | 2018-10-22 | 2018-12-11 | 上海上药新亚药业有限公司 | 一种头孢地嗪钠的精制方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2714880A1 (de) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
-
1981
- 1981-11-03 DE DE19813143537 patent/DE3143537A1/de not_active Withdrawn
-
1982
- 1982-11-01 FI FI823718A patent/FI75573C/fi not_active IP Right Cessation
- 1982-11-01 KR KR8204907A patent/KR880001412B1/ko not_active Expired
- 1982-11-01 IL IL67134A patent/IL67134A/xx not_active IP Right Cessation
- 1982-11-01 NO NO823625A patent/NO160582C/no not_active IP Right Cessation
- 1982-11-01 NZ NZ202332A patent/NZ202332A/en unknown
- 1982-11-01 GR GR69684A patent/GR76735B/el unknown
- 1982-11-02 AT AT82110072T patent/ATE24729T1/de not_active IP Right Cessation
- 1982-11-02 PH PH28074A patent/PH20488A/en unknown
- 1982-11-02 DE DE8282110072T patent/DE3274984D1/de not_active Expired
- 1982-11-02 JP JP57193245A patent/JPS5885893A/ja active Granted
- 1982-11-02 ES ES517024A patent/ES517024A0/es active Granted
- 1982-11-02 CA CA000414646A patent/CA1186682A/en not_active Expired
- 1982-11-02 DK DK486482A patent/DK163360C/da not_active IP Right Cessation
- 1982-11-02 PT PT75778A patent/PT75778A/pt unknown
- 1982-11-02 ZA ZA828004A patent/ZA828004B/xx unknown
- 1982-11-02 HU HU823506A patent/HU188604B/hu unknown
- 1982-11-02 EP EP82110072A patent/EP0078532B1/de not_active Expired
- 1982-11-02 IE IE2617/82A patent/IE54066B1/en not_active IP Right Cessation
- 1982-11-03 MA MA19850A patent/MA19638A1/fr unknown
-
1985
- 1985-08-28 US US06/770,406 patent/US4590267A/en not_active Expired - Lifetime
-
1991
- 1991-12-30 CS CS914156A patent/CS415691A3/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE24729T1 (de) | 1987-01-15 |
| MA19638A1 (fr) | 1983-07-01 |
| GR76735B (instruction) | 1984-08-30 |
| EP0078532B1 (de) | 1987-01-07 |
| ES8307823A1 (es) | 1983-08-01 |
| KR840002404A (ko) | 1984-07-02 |
| DK486482A (da) | 1983-05-04 |
| KR880001412B1 (ko) | 1988-08-01 |
| JPH045038B2 (instruction) | 1992-01-30 |
| EP0078532A3 (en) | 1984-09-12 |
| NO160582B (no) | 1989-01-23 |
| IL67134A0 (en) | 1983-03-31 |
| FI823718A0 (fi) | 1982-11-01 |
| JPS5885893A (ja) | 1983-05-23 |
| ZA828004B (en) | 1983-08-31 |
| DK163360B (da) | 1992-02-24 |
| DE3274984D1 (en) | 1987-02-12 |
| NZ202332A (en) | 1985-10-11 |
| CA1186682A (en) | 1985-05-07 |
| US4590267A (en) | 1986-05-20 |
| EP0078532A2 (de) | 1983-05-11 |
| DK163360C (da) | 1992-07-13 |
| DE3143537A1 (de) | 1983-05-11 |
| IE822617L (en) | 1983-05-03 |
| IL67134A (en) | 1986-01-31 |
| FI823718L (fi) | 1983-05-04 |
| FI75573B (fi) | 1988-03-31 |
| FI75573C (fi) | 1988-07-11 |
| CS415691A3 (en) | 1992-06-17 |
| PH20488A (en) | 1987-01-16 |
| ES517024A0 (es) | 1983-08-01 |
| NO823625L (no) | 1983-05-04 |
| IE54066B1 (en) | 1989-06-07 |
| HU188604B (en) | 1986-04-28 |
| PT75778A (de) | 1982-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |
Free format text: EXPIRED IN NOVEMBER 2002 |