DK391883A - Fremgangsmaade til fremstilling af et krystalliseret syreadditionssalt af 7-(2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido)-2-carboxy-3-(2-(5,6-dioxo-4-formylmethyl-1,4,5,6-tetrahydro-1,2,4-triazin-3 -yl)-thiovinyl)- 8-oxo-5-thia-1-azabicyclo(4.2.0)-2-octen (syn-isomer, form e) - Google Patents

Fremgangsmaade til fremstilling af et krystalliseret syreadditionssalt af 7-(2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido)-2-carboxy-3-(2-(5,6-dioxo-4-formylmethyl-1,4,5,6-tetrahydro-1,2,4-triazin-3 -yl)-thiovinyl)- 8-oxo-5-thia-1-azabicyclo(4.2.0)-2-octen (syn-isomer, form e) Download PDF

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Publication number
DK391883A
DK391883A DK391883A DK391883A DK391883A DK 391883 A DK391883 A DK 391883A DK 391883 A DK391883 A DK 391883A DK 391883 A DK391883 A DK 391883A DK 391883 A DK391883 A DK 391883A
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DK
Denmark
Prior art keywords
thiovinyl
methoxyiminoacetamido
formylmethyl
octen
thia
Prior art date
Application number
DK391883A
Other languages
English (en)
Other versions
DK391883D0 (da
Inventor
Christian Berger
Daniel Farge
Pierre Le Roy
Claude Moutonnier
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of DK391883D0 publication Critical patent/DK391883D0/da
Publication of DK391883A publication Critical patent/DK391883A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DK391883A 1982-08-27 1983-08-26 Fremgangsmaade til fremstilling af et krystalliseret syreadditionssalt af 7-(2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido)-2-carboxy-3-(2-(5,6-dioxo-4-formylmethyl-1,4,5,6-tetrahydro-1,2,4-triazin-3 -yl)-thiovinyl)- 8-oxo-5-thia-1-azabicyclo(4.2.0)-2-octen (syn-isomer, form e) DK391883A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8214700A FR2532315A1 (fr) 1982-08-27 1982-08-27 Formes cristallisees de sels d'addition avec des acides, de l'((amino-2-thiazolyl-4)-2 methoxyimino-2 acetamido)-7 carboxy-2 (dioxo-5,6 formylmethyl-4 tetrahydro-1,4,5,6 triazine-1,2,4 yl-3) thio-2 vinyl)-3 oxo-8 thia-5 aza-1 bicyclo(4.2.0) octene-2 isomere syn, forme e et leur preparation

Publications (2)

Publication Number Publication Date
DK391883D0 DK391883D0 (da) 1983-08-26
DK391883A true DK391883A (da) 1984-02-28

Family

ID=9277083

Family Applications (1)

Application Number Title Priority Date Filing Date
DK391883A DK391883A (da) 1982-08-27 1983-08-26 Fremgangsmaade til fremstilling af et krystalliseret syreadditionssalt af 7-(2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido)-2-carboxy-3-(2-(5,6-dioxo-4-formylmethyl-1,4,5,6-tetrahydro-1,2,4-triazin-3 -yl)-thiovinyl)- 8-oxo-5-thia-1-azabicyclo(4.2.0)-2-octen (syn-isomer, form e)

Country Status (10)

Country Link
EP (1) EP0102896A1 (da)
JP (1) JPS5959691A (da)
KR (1) KR840005817A (da)
AU (1) AU1844983A (da)
DK (1) DK391883A (da)
FI (1) FI833056A (da)
FR (1) FR2532315A1 (da)
HU (1) HUT34503A (da)
IL (1) IL69566A0 (da)
ZA (1) ZA836354B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3919259A1 (de) * 1989-06-13 1990-12-20 Hoechst Ag Kristalline cephem-saeureadditionssalze und verfahren zu ihrer herstellung
EP0638573A1 (en) * 1993-08-10 1995-02-15 Lucky Ltd. Crystalline hydrates of cephalosporin and process for preparation thereof
ATE440101T1 (de) 2003-03-27 2009-09-15 Basilea Pharmaceutica Ag Cephalosporin in kristalliner form

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1145744A (fr) * 1979-05-23 1983-05-03 Daniel Farge Thiovinyl-3 cephalosporines, leur preparation et les compositions qui les contiennent

Also Published As

Publication number Publication date
FR2532315A1 (fr) 1984-03-02
DK391883D0 (da) 1983-08-26
EP0102896A1 (fr) 1984-03-14
ZA836354B (en) 1984-04-25
HUT34503A (en) 1985-03-28
AU1844983A (en) 1984-03-01
FI833056A (fi) 1984-02-28
JPS5959691A (ja) 1984-04-05
KR840005817A (ko) 1984-11-19
FI833056A0 (fi) 1983-08-26
IL69566A0 (en) 1983-11-30

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