NO160582C - Fremgangsmaate til fremstilling av vannopploeselige dialkalimetallsalter av 7-beta-/2-2(aminotiazol-4-yl)-2-syn-metoksiminoacetamido/-3-(5-karboksylmetyl-4-metyl-1,3-diazol-2-yl-tiometyl)-cef-3-em-4-karboksylsyre. - Google Patents

Fremgangsmaate til fremstilling av vannopploeselige dialkalimetallsalter av 7-beta-/2-2(aminotiazol-4-yl)-2-syn-metoksiminoacetamido/-3-(5-karboksylmetyl-4-metyl-1,3-diazol-2-yl-tiometyl)-cef-3-em-4-karboksylsyre.

Info

Publication number
NO160582C
NO160582C NO823625A NO823625A NO160582C NO 160582 C NO160582 C NO 160582C NO 823625 A NO823625 A NO 823625A NO 823625 A NO823625 A NO 823625A NO 160582 C NO160582 C NO 160582C
Authority
NO
Norway
Prior art keywords
methyl
ceph
syn
beta
carboxylic acid
Prior art date
Application number
NO823625A
Other languages
English (en)
Norwegian (no)
Other versions
NO823625L (no
NO160582B (no
Inventor
Karl-Heinz Scheunemann
Burkhard Mencke
Juergen Blumbach
Walter Duerckheimer
Klaus Fleischmann
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO823625L publication Critical patent/NO823625L/no
Publication of NO160582B publication Critical patent/NO160582B/no
Publication of NO160582C publication Critical patent/NO160582C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
NO823625A 1981-11-03 1982-11-01 Fremgangsmaate til fremstilling av vannopploeselige dialkalimetallsalter av 7-beta-/2-2(aminotiazol-4-yl)-2-syn-metoksiminoacetamido/-3-(5-karboksylmetyl-4-metyl-1,3-diazol-2-yl-tiometyl)-cef-3-em-4-karboksylsyre. NO160582C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813143537 DE3143537A1 (de) 1981-11-03 1981-11-03 Kristalline salze von cefodizim und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
NO823625L NO823625L (no) 1983-05-04
NO160582B NO160582B (no) 1989-01-23
NO160582C true NO160582C (no) 1989-05-03

Family

ID=6145473

Family Applications (1)

Application Number Title Priority Date Filing Date
NO823625A NO160582C (no) 1981-11-03 1982-11-01 Fremgangsmaate til fremstilling av vannopploeselige dialkalimetallsalter av 7-beta-/2-2(aminotiazol-4-yl)-2-syn-metoksiminoacetamido/-3-(5-karboksylmetyl-4-metyl-1,3-diazol-2-yl-tiometyl)-cef-3-em-4-karboksylsyre.

Country Status (21)

Country Link
US (1) US4590267A (el)
EP (1) EP0078532B1 (el)
JP (1) JPS5885893A (el)
KR (1) KR880001412B1 (el)
AT (1) ATE24729T1 (el)
CA (1) CA1186682A (el)
CS (1) CS415691A3 (el)
DE (2) DE3143537A1 (el)
DK (1) DK163360C (el)
ES (1) ES8307823A1 (el)
FI (1) FI75573C (el)
GR (1) GR76735B (el)
HU (1) HU188604B (el)
IE (1) IE54066B1 (el)
IL (1) IL67134A (el)
MA (1) MA19638A1 (el)
NO (1) NO160582C (el)
NZ (1) NZ202332A (el)
PH (1) PH20488A (el)
PT (1) PT75778A (el)
ZA (1) ZA828004B (el)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60142987A (ja) * 1983-12-29 1985-07-29 Mochida Pharmaceut Co Ltd セフアロスポリン誘導体
DE150507T1 (de) * 1983-12-29 1987-02-26 Mochida Pharmaceutical Co., Ltd., Tokio/Tokyo Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
DE3405728A1 (de) * 1984-02-17 1985-08-22 Hoechst Ag, 6230 Frankfurt Verwendung von cephemverbindungen als immunmodulatoren
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
US4880798A (en) * 1986-11-25 1989-11-14 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
JPS63132893A (ja) * 1986-11-25 1988-06-04 Mochida Pharmaceut Co Ltd 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤
DE3911322A1 (de) * 1989-04-07 1990-10-11 Hoechst Ag Verfahren zur herstellung von cefodizim-dinatrium
DE3923541A1 (de) * 1989-07-15 1991-01-24 Hoechst Ag Cephalosporinderivate und verfahren zu ihrer herstellung
JP4731437B2 (ja) * 2006-09-25 2011-07-27 株式会社オーディオテクニカ コンデンサーマイクロホンユニットおよびコンデンサーマイクロホン
CN101723958B (zh) * 2008-10-22 2011-12-21 丽珠医药集团股份有限公司 头孢地嗪钠药物及制备方法
CN101830915A (zh) * 2010-05-13 2010-09-15 胡梨芳 头孢地嗪钠水合物及其制备方法和用途
CN102796118B (zh) * 2012-05-29 2013-12-04 浙江亚太药业股份有限公司 一种头孢地嗪钠化合物实体、制备方法及其药物制剂
CN102898443B (zh) * 2012-10-31 2015-12-16 天津青松华药医药有限公司 高收率超净高纯化头孢地嗪钠的精制方法
CN104031066B (zh) * 2014-05-21 2016-06-29 丽珠医药集团股份有限公司 一种头孢地嗪钠药物及制备方法
CN108976247A (zh) * 2018-10-22 2018-12-11 上海上药新亚药业有限公司 一种头孢地嗪钠的精制方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DK163360B (da) 1992-02-24
KR880001412B1 (ko) 1988-08-01
EP0078532A2 (de) 1983-05-11
EP0078532A3 (en) 1984-09-12
KR840002404A (ko) 1984-07-02
MA19638A1 (fr) 1983-07-01
IE54066B1 (en) 1989-06-07
HU188604B (en) 1986-04-28
CA1186682A (en) 1985-05-07
NO823625L (no) 1983-05-04
JPH045038B2 (el) 1992-01-30
FI823718L (fi) 1983-05-04
NZ202332A (en) 1985-10-11
JPS5885893A (ja) 1983-05-23
DK486482A (da) 1983-05-04
CS415691A3 (en) 1992-06-17
US4590267A (en) 1986-05-20
ZA828004B (en) 1983-08-31
IL67134A (en) 1986-01-31
FI75573C (fi) 1988-07-11
EP0078532B1 (de) 1987-01-07
IE822617L (en) 1983-05-03
DK163360C (da) 1992-07-13
NO160582B (no) 1989-01-23
GR76735B (el) 1984-08-30
DE3143537A1 (de) 1983-05-11
PH20488A (en) 1987-01-16
FI75573B (fi) 1988-03-31
ES517024A0 (es) 1983-08-01
FI823718A0 (fi) 1982-11-01
ES8307823A1 (es) 1983-08-01
ATE24729T1 (de) 1987-01-15
IL67134A0 (en) 1983-03-31
PT75778A (de) 1982-12-01
DE3274984D1 (en) 1987-02-12

Similar Documents

Publication Publication Date Title
NO160582C (no) Fremgangsmaate til fremstilling av vannopploeselige dialkalimetallsalter av 7-beta-/2-2(aminotiazol-4-yl)-2-syn-metoksiminoacetamido/-3-(5-karboksylmetyl-4-metyl-1,3-diazol-2-yl-tiometyl)-cef-3-em-4-karboksylsyre.
ES509957A0 (es) Procedimiento de obtencion de sin-isomeros de compuestos de partida de cefalosporina.
NO822932L (no) Analogifremgangsmaate for fremstilling av heterocykliske benzoforbindelser.
DK160092C (da) Analogifremgangsmaade til fremstilling af 2-(2-(1,4-benzodioxanyl))-2-imidazolin eller ikke-toxiske syreadditionssalte deraf
DK273479A (da) Fremgangsmaade til fremstilling af 5-phenylpyrazol-forbindelser eller salte deraf
SE7904731L (sv) Nya l-leucyl-4-hydroxianilidderivat
DK149429C (da) Analogifremgangsmaade til fremstilling af thiazolidin-2,4-dionderivater eller syreadditionssalte deraf
DK131940C (da) Analogifremgangsmade til fremstilling af 2,6-diphenyl-3-methyl-2,3-dihydro-imidazo(2,1-b)thiazol eller syreadditionssalte deraf
DK262685A (da) Polypeptider og salte deraf samt fremgangsmaade til fremstilling af saadanne forbindelser
ES486422A0 (es) Un procedimiento para la preparacion de nuevos compuestos iminicos heterociclicos.
DK136823B (da) Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive derivater af imidazo(2,1-b)thiazol eller syreadditionssalte deraf.
DK439082A (da) 4-acylamino-1-aza-adamantan-forbindelser samt fremgangsmaade til fremstilling deraf
SE8303465L (sv) Forfarande for framstellning av 2-(2-aminotiazol-4-yl)glyoxylsyraderivat eller ett salt derav och mellanprodukter herfor samt forfarande for framstellning av mellanprodukterna
DK148140C (da) Analogifremgangsmaade til fremstilling af 2-(aminoalkyl)-5-phenyl-hexahydro-trans-4a,9b-1(h)-pyrido(4,3-b)indolforbindelser eller syreadditionssalte deraf
DK66980A (da) Fremgangsmaade til fremstilling af azacyclyl (thio) ureidoacetamidocphem-forbindelser og salte deraf samt anvendelse deraf
DK391883A (da) Fremgangsmaade til fremstilling af et krystalliseret syreadditionssalt af 7-(2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido)-2-carboxy-3-(2-(5,6-dioxo-4-formylmethyl-1,4,5,6-tetrahydro-1,2,4-triazin-3 -yl)-thiovinyl)- 8-oxo-5-thia-1-azabicyclo(4.2.0)-2-octen (syn-isomer, form e)
ES481998A0 (es) Procedimiento de preparacion de derivados halogenados de la vincamina.
DK124682A (da) Fremgangsmaade til fremstilling af cephalosporinderivater eller syreadditionssalte deraf
DK149891C (da) Analogifremgangsmaade til fremstilling af spirobenzofuranon-forbindelser eller salte deraf med uorganiske eller organiske syrer eller alkalimetaller
DK143846C (da) Analogifremgangsmaade til fremstilling af 2-(indenyloxymethyl)morpholin-derivater eller syreadditionssalte deraf
DK146741C (da) Analogifremgangsmaade til fremstilling af alkylaminopropanolderivater af 2-methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazoler eller fysiologisk acceptable syreadditionssalte eller diastereomere salte deraf
ES512629A0 (es) Procedimiento para preparar una sal de pirimidona.
IL72435A (en) 2-(2-aminothiazol-4-yl)-3-(substituted)propenoic acid derivatives
SE7702735L (sv) Forfarande for framstellning av 7-alkoxi- eller 7-aralkoxi-3-brommetylcefemer
DK149531C (da) Analogifremgangsmaade til fremstilling af 3-(2-(3-oxo-4-morpholinyl)-ethylamino)-4-methyl-6-phenyl-pyridazinderivater eller farmaceutisk acceptable syreadditionssalte deraf

Legal Events

Date Code Title Description
MK1K Patent expired

Free format text: EXPIRED IN NOVEMBER 2002