NO155622C - Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrido- og isokinolin (1[,2[:1,2) imidazo (5,4-c) rifamycin sv og s derivater. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrido- og isokinolin (1[,2[:1,2) imidazo (5,4-c) rifamycin sv og s derivater.

Info

Publication number
NO155622C
NO155622C NO811731A NO811731A NO155622C NO 155622 C NO155622 C NO 155622C NO 811731 A NO811731 A NO 811731A NO 811731 A NO811731 A NO 811731A NO 155622 C NO155622 C NO 155622C
Authority
NO
Norway
Prior art keywords
isoqinoline
rifamycin
imidazo
derivatives
preparation
Prior art date
Application number
NO811731A
Other languages
English (en)
Norwegian (no)
Other versions
NO155622B (no
NO811731L (no
Inventor
Egido Marchi
Lauretta Montecchi
Original Assignee
Alfa Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Farmaceutici Spa filed Critical Alfa Farmaceutici Spa
Publication of NO811731L publication Critical patent/NO811731L/no
Publication of NO155622B publication Critical patent/NO155622B/no
Publication of NO155622C publication Critical patent/NO155622C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO811731A 1980-05-22 1981-05-21 Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrido- og isokinolin (1[,2[:1,2) imidazo (5,4-c) rifamycin sv og s derivater. NO155622C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03429/80A IT1154655B (it) 1980-05-22 1980-05-22 Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica

Publications (3)

Publication Number Publication Date
NO811731L NO811731L (no) 1981-11-23
NO155622B NO155622B (no) 1987-01-19
NO155622C true NO155622C (no) 1987-04-29

Family

ID=11107198

Family Applications (1)

Application Number Title Priority Date Filing Date
NO811731A NO155622C (no) 1980-05-22 1981-05-21 Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrido- og isokinolin (1[,2[:1,2) imidazo (5,4-c) rifamycin sv og s derivater.

Country Status (25)

Country Link
US (1) US4341785A (sr)
JP (1) JPS5711987A (sr)
AR (1) AR226212A1 (sr)
AT (1) AT373599B (sr)
AU (1) AU537093B2 (sr)
BE (1) BE888895A (sr)
CA (1) CA1142518A (sr)
CH (1) CH648037A5 (sr)
DE (1) DE3120460A1 (sr)
DK (1) DK157876C (sr)
EG (1) EG14891A (sr)
ES (1) ES502906A0 (sr)
FI (1) FI69467C (sr)
FR (1) FR2482967A1 (sr)
GB (1) GB2079270B (sr)
GR (1) GR75640B (sr)
IE (1) IE51204B1 (sr)
IT (1) IT1154655B (sr)
LU (1) LU83376A1 (sr)
NL (1) NL187022C (sr)
NO (1) NO155622C (sr)
PH (2) PH17207A (sr)
PT (1) PT73064B (sr)
SE (1) SE453089B (sr)
ZA (1) ZA813430B (sr)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1199374B (it) * 1984-05-15 1988-12-30 Alfa Farmaceutici Spa Processo per la preparazione di pirido-imidazo-rifamicine
IT1264494B1 (it) * 1993-03-23 1996-09-24 Alfa Wassermann Spa Uso di rifaximin e di formulazioni che la contengono nel trattamento delle dispepsie gastriche originate da helicobacter
US7048906B2 (en) 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
US6861053B1 (en) * 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
US5981522A (en) * 1995-09-01 1999-11-09 Kaneka Corporation Treatment of disease caused by infection of Helicobacter
DE69829905T2 (de) * 1997-02-28 2006-03-09 Kaneka Corp. Heilmittel für durch Helicobacter verursachte Krankheit
CA2465846A1 (en) * 2001-11-21 2003-06-05 Activbiotics, Inc. Targeted therapeutics and uses thereof
WO2003051299A2 (en) * 2001-12-13 2003-06-26 Activbiotics, Inc. Sulfhydryl rifamycins and uses thereof
EP1560566B1 (en) * 2002-11-05 2012-04-11 Fadim S.r.l. Controlled and continued delivery of rifaximin
US7820652B2 (en) * 2003-09-24 2010-10-26 Activbiotics Pharma, Llc Regimen for the administration of rifamycin-class antibiotics
US7902206B2 (en) * 2003-11-07 2011-03-08 Alfa Wassermann, S.P.A. Polymorphic forms α, β and γ of rifaximin
US20080262024A1 (en) * 2003-11-07 2008-10-23 Giuseppe Claudio Viscomi Rifaximin compositions and method of use
US7923553B2 (en) * 2003-11-07 2011-04-12 Alfa Wassermann, S.P.A. Processes for the production of polymorphic forms of rifaximin
US7906542B2 (en) * 2004-11-04 2011-03-15 Alfa Wassermann, S.P.A. Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin
ITMI20032144A1 (it) * 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
US7265107B2 (en) * 2004-03-10 2007-09-04 Cumbre Pharmaceuticals Inc. Rifamycin C-11 oxime cyclo derivatives effective against drug-resistant microbes
US7256187B2 (en) * 2004-03-10 2007-08-14 Cumbre Pharmaceuticals Inc. Rifamycin C-11 oxime derivatives effective against drug-resistant microbes
US7202246B2 (en) * 2004-06-09 2007-04-10 Cumbre Pharmaceuticals Inc. Spiro-rifamycin derivatives targeting RNA polymerase
US20060210492A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Use of rifaximin for treatment and prevention of periodontal conditions
US8003118B2 (en) * 2005-03-02 2011-08-23 Kodsi Robert E Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis
US20060210483A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections
EP1698630B1 (en) 2005-03-03 2014-09-03 ALFA WASSERMANN S.p.A. New polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations
ITBO20050123A1 (it) 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
CA2618741C (en) 2005-08-11 2014-03-25 Targanta Therapeutics Inc. Phosphonated rifamycins and uses thereof for the prevention and treatment of bone and joint infections
KR101398648B1 (ko) 2006-03-09 2014-06-27 샐릭스 파마슈티컬스 인코포레이티드 리팍시민 직장 기능장애 치료 제제
WO2008016708A2 (en) 2006-08-02 2008-02-07 Salix Pharmaceuticals, Inc. Methods for treatment of radiation enteritis
ITMI20061692A1 (it) 2006-09-05 2008-03-06 Alfa Wassermann Spa Uso di polioli per ottenere forme polimorfe stabili di rifaximina
AU2007298733B2 (en) * 2006-09-22 2012-11-08 Cipla Limited Rifaximin
US20080159987A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Restless Legs Syndrome
US20080161337A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Chronic Prostatitis
ITMI20071241A1 (it) * 2007-06-20 2008-12-21 Solmag S P A Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta
PT2011486E (pt) 2007-07-06 2012-08-24 Lupin Ltd Composições farmacêuticas de rifaximina
JP5755878B2 (ja) 2007-07-06 2015-07-29 ルパン リミテッドLupin Limited リファキシミンの薬剤組成物
US7709634B2 (en) * 2007-09-20 2010-05-04 Apotex Pharmachem Inc. Amorphous form of rifaximin and processes for its preparation
US8486956B2 (en) 2008-02-25 2013-07-16 Salix Pharmaceuticals, Ltd Forms of rifaximin and uses thereof
EP2257557A4 (en) * 2008-02-25 2011-06-29 Salix Pharmaceuticals Ltd FORMS OF RIFAXIMINE AND APPLICATIONS THEREOF
ES2727728T3 (es) 2008-02-26 2019-10-18 Salix Pharmaceuticals Ltd Métodos para el tratamiento del síndrome del intestino irritable
US11779571B2 (en) 2008-02-26 2023-10-10 Salix Pharmaceuticals, Inc. Methods for treating irritable bowel syndrome (IBS)
WO2009137672A1 (en) 2008-05-07 2009-11-12 Salix Pharmaceuticals, Ltd. Methods of treating bowel disease by administering a bowel cleanser and an antibiotic
US8524691B2 (en) 2008-08-13 2013-09-03 The Medicines Company Phosphonated rifamycins and uses thereof for the prevention and treatment of bone and joint infections
PT2327407E (pt) 2008-09-26 2014-09-10 Aska Pharm Co Ltd Agentes profiláticos e/ou terapêuticos para desordens gastrointestinais funcionais
US12285414B2 (en) 2008-10-02 2025-04-29 Salix Pharmaceuticals, Inc. Methods of treating hepatic encephalopathy
DK3628319T3 (da) 2008-10-02 2024-03-04 Salix Pharmaceuticals Ltd Behandling af hepatisk encefalopati ved anvendelse af rifaximin
KR20110107806A (ko) 2008-12-10 2011-10-04 시플라 리미티드 리팍시민 복합체
IT1397617B1 (it) * 2009-04-20 2013-01-18 Alfa Wassermann Spa Nuovi derivati della rifamicina
RU2540513C2 (ru) 2009-06-02 2015-02-10 Саликс Фармасьютикалз, Лтд. Способы лечения печеночной энцефалопатии
WO2011032085A1 (en) 2009-09-13 2011-03-17 Salix Pharmaceuticals, Ltd. Methods for treating irritable bowel syndrome (ibs)
SG10201501054TA (en) 2009-10-27 2015-04-29 Lupin Ltd Solid dispersion of rifaximin
AU2010320656B2 (en) 2009-11-23 2015-07-30 Cipla Limited Topical foam composition
WO2011080691A1 (en) 2009-12-28 2011-07-07 Silvio Massimo Lavagna Method for the production of amorphous rifaximin
AU2011218129A1 (en) 2010-02-18 2012-08-23 Board Of Regents Of The University Of Texas System Methods for treating infection
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
US9211258B2 (en) 2010-03-10 2015-12-15 Lupin Limited Rifaximin ready-to-use suspension
WO2012009387A1 (en) 2010-07-12 2012-01-19 Salix Pharmaceuticals, Ltd Formulations of rifaximin and uses thereof
WO2012035544A2 (en) 2010-09-13 2012-03-22 Sequent Scientific Ltd. A novel polymorphic form of rifaximin and process for its preparation
CA2825964A1 (en) 2011-02-11 2012-08-16 Salix Pharmaceuticals, Ltd. Forms of rifaximin and uses thereof
CA2834829A1 (en) 2011-05-02 2012-11-08 Ranbaxy Laboratories Limited Rifaximin dimethylformamide solvate
ITMI20110890A1 (it) 2011-05-19 2012-11-20 A M S A Anonima Materie Sint & Affini S P A Polimorfo di rifaximina e processo per la sua preparazione
ITBO20110461A1 (it) 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
RU2496475C2 (ru) 2011-10-26 2013-10-27 Александр Васильевич Иващенко Фармацевтическая композиция и набор для лечения бактериальных инфекций
ES2986825T3 (es) 2011-11-02 2024-11-12 Salix Pharmaceuticals Inc Rifaximina para la repetición de tratamiento del síndrome del intestino irritable con predominio de diarrea
AU2013212008A1 (en) 2012-01-25 2014-07-10 Alfa Wassermann S.P.A. Rifaximin derivative and uses thereof
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
US9849090B2 (en) 2012-12-12 2017-12-26 Sun Pharmaceutical Industries Limited Pharmaceutical compositions of rifaximin
US20160047819A1 (en) 2013-03-15 2016-02-18 Alfa Wassermann S.P.A. Method for diagnosing vaginal infections
EP2968283A1 (en) 2013-03-15 2016-01-20 ALFA WASSERMANN S.p.A. Rifaximin for use in the treating of vaginal infections.
KR102190173B1 (ko) 2013-04-12 2020-12-14 알파시그마 에스.피.에이. Nsaid 투여 및 관련 조성물, 방법 및 시스템
US9018225B1 (en) 2013-07-26 2015-04-28 Novel Laboratories Rifaximin crystalline forms and methods of preparation thereof
ES2621557T3 (es) 2014-03-31 2017-07-04 Euticals S.P.A. Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas
CA2946101A1 (en) * 2014-04-19 2015-10-22 Granules India Limited An improved process for the preparation of rifamycin derivatives
CN106795192B (zh) 2014-05-04 2020-06-16 萨利克斯药品公司 Ibs微生物群及其用途
EP3143027B1 (en) 2014-05-12 2019-07-10 Alfasigma S.p.A. New solvated crystal form of rifaximin, production, compositions and uses thereof
EP2982764A1 (en) 2014-08-05 2016-02-10 ALFA WASSERMANN S.p.A. Identification of vaginal bacteria
US9988398B2 (en) 2016-06-07 2018-06-05 Cadila Healthcare Limited Crystalline form of rifaximin and process for its preparation
PT3518924T (pt) 2016-09-30 2022-10-27 Salix Pharmaceuticals Inc Formas de dispersão sólidas de rifaximina
IT201700091912A1 (it) * 2017-08-08 2019-02-08 Biofer Spa Nuove pirido-imidazo rifamicine
RU2020102511A (ru) 2017-06-26 2021-07-27 Биофер С.П.А. Соединения пиридо-имидазо рифамицина в качестве антибактериального средства

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE273377C (sr) *
AT273377B (de) * 1967-03-01 1969-08-11 Lepetit Spa Verfahren zur Herstellung von neuen Rifamycinen
AT344898B (de) * 1975-06-13 1978-08-10 Archifar Ind Chim Trentino Verfahren zur herstellung neuer rifamycin-verbindungen
DK345977A (da) * 1976-09-30 1978-03-31 Archifar Ind Chim Trentino G rifamycinforbindelser og fremgangsmaade til deres fremstillin
CH629212A5 (it) * 1976-10-18 1982-04-15 Erba Farmitalia Procedimento per la preparazione di composti di rifamicina.
CH633014A5 (en) * 1978-06-09 1982-11-15 Erba Farmitalia Rifamycin compounds

Also Published As

Publication number Publication date
GR75640B (sr) 1984-08-02
LU83376A1 (fr) 1981-09-11
AR226212A1 (es) 1982-06-15
IT1154655B (it) 1987-01-21
FI69467B (fi) 1985-10-31
GB2079270A (en) 1982-01-20
JPS6123192B2 (sr) 1986-06-04
EG14891A (en) 1985-12-31
IE811139L (en) 1981-11-22
ES8203388A1 (es) 1982-04-01
SE453089B (sv) 1988-01-11
FR2482967B1 (sr) 1985-03-29
CA1142518A (en) 1983-03-08
FI811565L (fi) 1981-11-23
PH18704A (en) 1985-09-05
CH648037A5 (de) 1985-02-28
ES502906A0 (es) 1982-04-01
JPS5711987A (en) 1982-01-21
PT73064A (en) 1981-06-01
ATA222781A (de) 1983-06-15
AU7065581A (en) 1981-11-26
NL187022B (nl) 1990-12-03
DE3120460C2 (sr) 1990-12-13
IT8003429A0 (it) 1980-05-22
DE3120460A1 (de) 1982-03-11
AU537093B2 (en) 1984-06-07
NO155622B (no) 1987-01-19
PH17207A (en) 1984-06-19
AT373599B (de) 1984-02-10
BE888895A (fr) 1981-09-16
FI69467C (fi) 1986-02-10
ZA813430B (en) 1982-06-30
DK157876C (da) 1990-07-30
FR2482967A1 (fr) 1981-11-27
DK157876B (da) 1990-02-26
NL187022C (nl) 1991-05-01
PT73064B (en) 1982-07-05
SE8103216L (sv) 1981-11-23
GB2079270B (en) 1984-01-18
NL8102290A (nl) 1981-12-16
IE51204B1 (en) 1986-10-29
US4341785A (en) 1982-07-27
DK224781A (da) 1981-11-23
NO811731L (no) 1981-11-23

Similar Documents

Publication Publication Date Title
NO155622C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrido- og isokinolin (1[,2[:1,2) imidazo (5,4-c) rifamycin sv og s derivater.
NO157781C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive, nye imidazo(1,2-a)pyridiner.
NO853100L (no) Fremgangsmaate for fremstilling av terapeutisk aktive imidazo-pyridiner.
NO158100C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive imidazo (4,5-c)pyridinderivater.
NO157620C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive imidazo -diazepiner.
NO156752C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 3-(1-piperidinylalkyl)-4hpyrido(1,2-a)pyrimidin-4-0n derivater
NO158099C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive karbostyrilderivater.
NO156373C (no) AnalogifremgangsmŸte for fremstilling av terapeutisk aktive furo-(3,4-c)-pyridinderivater.
NO156864C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive piperinderivater.
NO157819C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazo (1,2-a)-pyridin-2-yl-karbostyrilforbindelser.
NO884231D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive imidazopyridin-derivater.
NO161802C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive furo-(3,4-c)-pyridinderivater.
NO147564C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme 5-benzyol-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrol-1-karboksylsyrederivater
NO161319C (no) Analogifremgangsmaate til fremstilling av terapeutisk virksomme imidazo-(1,5-a)pyridin-derivater.
NO167739C (no) Anologifremgangsmaate for fremstilling av terapeutisk aktive ginkolid-derivater.
NO153137C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte pyrido(1,2-a)pyrimidiner.
NO160512C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive karbostyrilderivater.
NO159276C (no) Analogifremgangsmaate til fremstilling av terapeutisk virksomme imidazo(1,5-a)pyridiner.
NO162617C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive tricykliske imidazolderivater.
NO160442C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive pyrazolo (1,5-a)pyridinderivater.
NO853099L (no) Fremgangsmaate for fremstilling av terapeutisk aktive imidazo-kinoliner.
NO154052C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive kinolon-derivater.
NO162072C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive tienopyridinderivater.
NO854277L (no) Fremgangsmaate for fremstilling av terapeutisk aktive 6-fenetylaminoalkyl-7-hydroksy-furo-(3,4-c)-pyridin-derivater.
NO833770L (no) Fremgangsmaate for fremstilling av terapeutisk aktive (1,2,4) triazolo (4,3-a) kinoksalin-4-amin-derivater