NL9002366A - Nieuwe isoindoolderivaten en zouten daarvan, werkwijze voor de bereiding ervan en antitumorpreparaten die deze derivaten bevatten. - Google Patents
Nieuwe isoindoolderivaten en zouten daarvan, werkwijze voor de bereiding ervan en antitumorpreparaten die deze derivaten bevatten. Download PDFInfo
- Publication number
- NL9002366A NL9002366A NL9002366A NL9002366A NL9002366A NL 9002366 A NL9002366 A NL 9002366A NL 9002366 A NL9002366 A NL 9002366A NL 9002366 A NL9002366 A NL 9002366A NL 9002366 A NL9002366 A NL 9002366A
- Authority
- NL
- Netherlands
- Prior art keywords
- group
- compound
- general formula
- unsubstituted
- formula
- Prior art date
Links
- 0 C*1C(C)=CC(C(*C2*3)C4C2(C)*=C(CC(O2)=O)C3C2=O)C4C=C1 Chemical compound C*1C(C)=CC(C(*C2*3)C4C2(C)*=C(CC(O2)=O)C3C2=O)C4C=C1 0.000 description 4
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP28554889 | 1989-11-01 | ||
| JP20544390 | 1990-08-02 | ||
| JP2-288069A JP3027599B2 (ja) | 1990-08-02 | 1990-10-25 | 新規なイソインドール誘導体およびその塩 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL9002366A true NL9002366A (nl) | 1991-06-03 |
Family
ID=27328497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL9002366A NL9002366A (nl) | 1989-11-01 | 1990-10-31 | Nieuwe isoindoolderivaten en zouten daarvan, werkwijze voor de bereiding ervan en antitumorpreparaten die deze derivaten bevatten. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5166204A (de) |
| BE (1) | BE1004069A3 (de) |
| CA (1) | CA2028960C (de) |
| CH (1) | CH682151A5 (de) |
| DE (1) | DE4034687C2 (de) |
| DK (1) | DK261890A (de) |
| FR (1) | FR2655345B1 (de) |
| GB (1) | GB2239013B (de) |
| IT (1) | IT1242004B (de) |
| NL (1) | NL9002366A (de) |
| SE (1) | SE509700C2 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9215361D0 (en) * | 1992-07-20 | 1992-09-02 | Wellcome Found | Heterocyclic compounds |
| ES2123873T3 (es) * | 1994-08-04 | 1999-01-16 | Hoffmann La Roche | Pirrolocarbazol. |
| AU4889496A (en) * | 1995-03-09 | 1996-10-02 | Kyowa Hakko Kogyo Co. Ltd. | Pyrrolocarbazole derivatives |
| FR2751655B1 (fr) * | 1996-07-26 | 1998-08-28 | Adir | Nouveaux derives de bis-imides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| DE19744257B4 (de) * | 1997-10-07 | 2004-04-15 | Zentaris Gmbh | Beta-Carboline und deren Verwendung zur Behandlung von malignen und anderen, auf pathologischen Zellproliferationen beruhenden Erkrankungen |
| US20060276497A1 (en) * | 2000-05-09 | 2006-12-07 | Cephalon, Inc. | Novel multicyclic compounds and the use thereof |
| US7122679B2 (en) * | 2000-05-09 | 2006-10-17 | Cephalon, Inc. | Multicyclic compounds and the use thereof |
| EP1464645A1 (de) * | 2001-12-18 | 2004-10-06 | Kyowa Hakko Kogyo Co., Ltd. | Indolderivat |
| CA2483496A1 (en) * | 2002-04-26 | 2003-11-06 | Warner-Lambert Company Llc | Inhibitors of checkpoint kinases (wee1 and chk1) |
| CN100400529C (zh) * | 2003-10-08 | 2008-07-09 | 中国科学院化学研究所 | 含氟芳香族有机四酸二酐及制备方法和用途 |
| JP4857452B2 (ja) | 2004-03-15 | 2012-01-18 | ピーティーシー セラピューティクス，インコーポレーテッド | 血管新生の抑制に有用なカルボリン誘導体 |
| US7767689B2 (en) * | 2004-03-15 | 2010-08-03 | Ptc Therapeutics, Inc. | Carboline derivatives useful in the treatment of cancer |
| US8076352B2 (en) * | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Administration of carboline derivatives useful in the treatment of cancer and other diseases |
| US8940896B2 (en) * | 2004-03-15 | 2015-01-27 | Ptc Therapeutics, Inc. | Tetra-cyclic carboline derivatives useful in the inhibition of angiogenesis |
| US8076353B2 (en) * | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Inhibition of VEGF translation |
| CN101102765A (zh) * | 2004-11-23 | 2008-01-09 | Ptc医疗公司 | 通过翻译控制抑制vegf产生的活性物质四氢咔唑 |
| US8946444B2 (en) * | 2004-11-23 | 2015-02-03 | Ptc Therapeutics, Inc. | Tetrahydrocarbazoles as active agents for inhibiting VEGF production by translational control |
| CN110464722B (zh) * | 2019-06-06 | 2023-05-23 | 暨南大学 | 一类小分子化合物或其药学上可接受的盐在制备抗肿瘤转移药物中的应用 |
| CN115594681B (zh) * | 2022-10-21 | 2024-06-18 | 广州六顺生物科技有限公司 | 一种异吲哚啉-1,3-二酮衍生物及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3752123T2 (de) * | 1987-03-09 | 1998-05-14 | Kyowa Hakko Kogyo Kk | Derivate des physiologisch aktiven mittels k-252 |
| DE3833008A1 (de) * | 1988-09-29 | 1990-04-05 | Goedecke Ag | Pyrrolocarbozol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel |
-
1990
- 1990-10-30 GB GB9023568A patent/GB2239013B/en not_active Expired - Fee Related
- 1990-10-30 US US07/605,430 patent/US5166204A/en not_active Expired - Fee Related
- 1990-10-31 CH CH3464/90A patent/CH682151A5/de not_active IP Right Cessation
- 1990-10-31 DK DK261890A patent/DK261890A/da not_active Application Discontinuation
- 1990-10-31 IT IT48430A patent/IT1242004B/it active IP Right Grant
- 1990-10-31 DE DE4034687A patent/DE4034687C2/de not_active Expired - Fee Related
- 1990-10-31 CA CA002028960A patent/CA2028960C/en not_active Expired - Fee Related
- 1990-10-31 NL NL9002366A patent/NL9002366A/nl not_active Application Discontinuation
- 1990-10-31 FR FR9013552A patent/FR2655345B1/fr not_active Expired - Fee Related
- 1990-10-31 BE BE9001032A patent/BE1004069A3/fr not_active IP Right Cessation
- 1990-10-31 SE SE9003476A patent/SE509700C2/sv not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US5166204A (en) | 1992-11-24 |
| DE4034687C2 (de) | 1999-12-02 |
| CH682151A5 (de) | 1993-07-30 |
| DK261890D0 (da) | 1990-10-31 |
| DE4034687A1 (de) | 1991-05-02 |
| BE1004069A3 (fr) | 1992-09-15 |
| SE509700C2 (sv) | 1999-02-22 |
| IT9048430A1 (it) | 1992-05-01 |
| IT1242004B (it) | 1994-02-02 |
| GB2239013A (en) | 1991-06-19 |
| GB2239013B (en) | 1993-06-02 |
| IT9048430A0 (it) | 1990-10-31 |
| FR2655345A1 (de) | 1991-06-07 |
| SE9003476L (sv) | 1992-05-01 |
| DK261890A (da) | 1991-05-02 |
| CA2028960C (en) | 1999-01-19 |
| SE9003476D0 (sv) | 1990-10-31 |
| FR2655345B1 (de) | 1993-02-26 |
| GB9023568D0 (en) | 1990-12-12 |
| CA2028960A1 (en) | 1991-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AK | Correction of former applications already laid open |
Free format text: IN PAT.BUL.11/91,PAGE 1387:SHOULD BE DELETED |
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| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| BV | The patent application has lapsed |